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Journal Articles

Interferon-Activated Gene Signatures Associate with Chemotherapy Resistance and Sensitivity to JAK-Inhibition in Refractory ETP-ALL

Jason Xu, Jonathan Sussman, Austin Yang, Satoshi Yoshimura, Changya Chen, Omar Elghawy, Tiffaney Vincent, Caroline Diorio, Shovik Bandyopadyay, Jianzhong Hu, Alexander Lai Li, Gregory M. Chen, Chia-Hui Chen, Rawan Shraim, Haley Newman, Yang Ding, Elizabeth Li, Wenbao Yu, Anusha Thadi, Kyung Jin Ahn, Petri Pölönen, Abdelrahman Elsayed, David Frank, Elizabeth A. Raetz, Mignon L. Loh, Brent L. Wood, Stuart S. Winter, Kimberly P. Dunsmore, Meenakshi Devidas, Chunxu Qu, Stanley Pounds, Stephen P. Hunger, Charles G. Mullighan, Jun J. Yang, Kai Tan, David T. Teachey
Journal: Blood
Blood (2024) 144 (Supplement 1): 1464.
https://doi.org/10.1182/blood-2024-211090
Published: 2024
Journal Articles

In Vivo Persistence and Function of CAR19 T-Cell Products for Pediatric B-Cell Acute Lymphoblastic Leukemia Are Impacted By Media, Cytokine Supplementation and Metabolite Bioavailability during Ex Vivo Manufacturing

Caitlin R. Hopkins, Amanda M. DiNofia, Shannon L. Maude, Gregory M. Chen, Kwame Attah M. Boateng-Antwi, Jessica Perazzelli, Andres F. Mendez Corea, Alexander Shestov, Mercy Gohil, Yimei Li, Wei-Ting Hwang, Bakir Valentić, Shannon Christensen, Julie Jadlowsky, Regina M. Myers, Caroline Diorio, Megan M. Davis, Theresa Colligon, Gabriela Plesa, Don L. Siegel, Bruce Levine, Carl H. June, Roddy S. O'Connor, Stephan A. Grupp, Joseph A. Fraietta
Journal: Blood
Blood (2024) 144 (Supplement 1): 3473.
https://doi.org/10.1182/blood-2024-210324
Published: 2024
Journal Articles

Endothelial Cell Activation Enhances Thromboinflammation in Vitt

Alexander Dupuy, Xiaoming Liu, Jessica Tieng, Bede Johnston, Arian Nasser, Paul Coleman, Yingqi Zhang, Lining Arnold Ju, Huyen Tran, Vivien M Chen, Elizabeth E. Gardiner, Freda H. Passam
Journal: Blood
Blood (2022) 140 (Supplement 1): 1656–1657.
https://doi.org/10.1182/blood-2022-168441
Published: 2022
Journal Articles

TMEM16E Regulates Endothelial Cell Procoagulant Activity and Thrombosis

Alec A Schmaier, Papa Freduah Anderson, Siyu M Chen, Emale Darzi, Kelsey Sack, Criss Hartzell, Robert Flaumenhaft, Samir Parikh, Sol Schulman
Journal: Blood
Blood (2022) 140 (Supplement 1): 1654–1655.
https://doi.org/10.1182/blood-2022-159639
Published: 2022
Journal Articles

The Clinicalpathological Features of Vaccine-Induced Immune Thrombocytopenia and Thrombosis (VITT) Following ChAdOx1 (AstraZeneca AZD1222) Vaccination and Case Outcomes in Australia

Huyen Tran, Lucy Deng, Nicholas Wood, Vivien M Chen
Journal: Blood
Blood (2022) 140 (Supplement 1): 5654–5655.
https://doi.org/10.1182/blood-2022-168844
Published: 2022
Journal Articles

Early Clinical Evaluation of Potential Synergy of Targeted Radiotherapy with Lintuzumab-Ac225 and Venetoclax in Relapsed/Refractory AML

Gary J. Schiller, Laura Finn, Mohamed M. Hegazi, Johnnie J. Orozco, Avinash Desai, Mary M Chen, Gail J. Roboz
Journal: Blood
Blood (2022) 140 (Supplement 1): 3336–3337.
https://doi.org/10.1182/blood-2022-157588
Published: 2022
Journal Articles

Lintuzumab-Ac225 with Combination with Intensive Chemotherapy Yields High Response Rate and MRD Negativity in R/R AML with Adverse Features

Sameem Abedin, Guru Subramanian Guru Murthy, Aniko Szabo, Mehdi Hamadani, Laura C. Michaelis, Karen-Sue Carlson, Lyndsey Runaas, Katelyn Gauger, Avinash G Desai, Mary M Chen, Alexandra M. Harrington, Ehab L. Atallah
Journal: Blood
Blood (2022) 140 (Supplement 1): 157–158.
https://doi.org/10.1182/blood-2022-157827
Published: 2022
Journal Articles

Early Clinical Evaluation of Potential Synergy of Targeted Radiotherapy with Lintuzumab-Ac225 and Venetoclax in Relapsed/Refractory AML

Gary J. Schiller, Laura Finn, Gail J. Roboz, Johnnie J. Orozco, Tiffany Lin, Mary M Chen, Mohamed M. Hegazi
Journal: Blood
Blood (2021) 138 (Supplement 1): 3412.
https://doi.org/10.1182/blood-2021-146018
Published: 2021
Journal Articles

Decade-Long Remissions of Leukemia Sustained By the Persistence of Activated CD4+ CAR T-Cells

J. Joseph Melenhorst, Gregory M Chen, Meng Wang, David L. Porter, Peng Gao, Shovik Bandyopadhyay, Iulian Pruteanu-Malinici, Christopher L Nobles, Sayantan Maji, Noelle V Frey, Saar Gill, Lifeng Tian, Irina Kulikovskaya, Megan M Davis, Joseph A Fraietta, Jennifer L Brogdon, Regina Young, David E Ambrose, Anne Chew, Bruce L Levine, Don L. Siegel, Cécile Alanio, E. John Wherry, Frederic D. Bushman, Simon F Lacey, Kai Tan, Carl H June
Journal: Blood
Blood (2021) 138 (Supplement 1): 166.
https://doi.org/10.1182/blood-2021-152664
Published: 2021
Journal Articles

The clinical and functional effects of TERT variants in myelodysplastic syndrome

Christopher R. Reilly, Mikko Myllymäki, Robert Redd, Shilpa Padmanaban, Druha Karunakaran, Valerie Tesmer, Frederick D. Tsai, Christopher J. Gibson, Huma Q. Rana, Liang Zhong, Wael Saber, Stephen R. Spellman, Zhen-Huan Hu, Esther H. Orr, Maxine M. Chen, Immaculata De Vivo, Daniel J. DeAngelo, Corey Cutler, Joseph H. Antin, Donna Neuberg, Judy E. Garber, Jayakrishnan Nandakumar, Suneet Agarwal, R. Coleman Lindsley
Journal: Blood
Blood (2021) 138 (10): 898–911.
https://doi.org/10.1182/blood.2021011075
Published: 2021
Includes: Supplemental data
Journal Articles

Short telomere length predicts nonrelapse mortality after stem cell transplantation for myelodysplastic syndrome

Clinical Trials & Observations
Mikko Myllymäki, Robert Redd, Christopher R. Reilly, Wael Saber, Stephen R. Spellman, Christopher J. Gibson, Zhen-Huan Hu, Tao Wang, Esther H. Orr, Jaclyn G. Grenier, Maxine M. Chen, David P. Steensma, Corey Cutler, Immaculata De Vivo, Joseph H. Antin, Donna Neuberg, Suneet Agarwal, R. Coleman Lindsley
Journal: Blood
Blood (2020) 136 (26): 3070–3081.
https://doi.org/10.1182/blood.2020005397
Published: 2020
Includes: Supplemental data
Journal Articles

High E-Selectin Ligand Expression Contributes to Chemotherapy-Resistance in Poor Risk Relapsed and Refractory (R/R) Acute Myeloid Leukemia (AML) Patients and Can be Overcome with the Addition of Uproleselan

Daniel J. DeAngelo, MD PhD, Brian A Jonas, MD PhD, Jane L. Liesveld, MD, Dale L. Bixby, MD, Anjali S. Advani, MD, Paula Marlton, MBBS (Hons), FRACP, FRCPA, Michael E O'Dwyer, MD, William E. Fogler, PhD, John L. Magnani, PhD, Mary M Chen, MD PhD, Eric J. Feldman, MD, Helen M Thackray, MD, Pamela S. Becker, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2690.
https://doi.org/10.1182/blood-2019-123744
Published: 2019
Journal Articles

A Double-Blind, Placebo-Controlled, Phase 3 Registration Trial to Evaluate the Efficacy of Uproleselan (GMI-1271) with Standard Salvage Chemotherapy in Patients with Relapsed/Refractory (R/R) Acute Myeloid Leukemia

Daniel J. DeAngelo, MD PhD, Harry P. Erba, MD PhD, Brian A Jonas, MD PhD, Michael E O'Dwyer, MD, Paula Marlton, MBBS (Hons), FRACP, FRCPA, Gerwin Huls, MD PhD, Jane L. Liesveld, MD, Brenda Cooper, MD, Bhavana Bhatnagar, DO, Geoffrey L. Uy, MD, Gavin Cull, MB, BS, FRACP, FRCPA, Michael B. Armstrong, MD PhD, William E. Fogler, PhD, Mary M Chen, MD PhD, John L. Magnani, PhD, Helen M Thackray, MD, Eric J. Feldman, MD, Anjali S. Advani, MD, Pamela S. Becker, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2650.
https://doi.org/10.1182/blood-2019-123816
Published: 2019
Journal Articles

Telomere Length and Telomerase Complex Mutations Predict Fatal Treatment Toxicity after Stem Cell Transplantation in Patients with Myelodysplastic Syndrome

Mikko Myllymaki, MD PhD, Robert A. Redd, MS, Corey S. Cutler, MD MPH, Wael Saber, MD MS, Zhen-Huan Hu, MPH, Tao Wang, PhD, Stephen R. Spellman, Christopher J. Gibson, MD, Maxine M Chen, Esther Orr, David P. Steensma, MD, Joseph H. Antin, MD, Immaculata De Vivo, Donna S Neuberg, ScD, Suneet Agarwal, MDPhD, R. Coleman Lindsley, MD, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 796.
https://doi.org/10.1182/blood-2018-99-117031
Published: 2018
Journal Articles

Cisplatin Fails To Stimulate Production Of Reactive Oxygen Species and Release Of Neutrophil Extracellular Traps By Human Neutrophils In Vitro

Leonardo Pasalic, MBBS, Campbell Heather, BSc, Shane Thomas, PhD, Vivien M Chen, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4714.
https://doi.org/10.1182/blood.V122.21.4714.4714
Published: 2013
Journal Articles

Procoagulant Role Of Necrotic Platelets Demonstrated Using Novel Platelet Necrosis Marker

Minh Hua, MBBS, Leonardo Pasalic, MBBS, Robert Lindeman, MBBS, Philip Hogg, PhD, Vivien M Chen, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3512.
https://doi.org/10.1182/blood.V122.21.3512.3512
Published: 2013
Journal Articles

Laser-induced endothelial cell activation supports fibrin formation

Ben T. Atkinson, Reema Jasuja, Vivien M. Chen, Prathima Nandivada, Bruce Furie, Barbara C. Furie
Journal: Blood
Blood (2010) 116 (22): 4675–4683.
https://doi.org/10.1182/blood-2010-05-283986
Published: 2010
Journal Articles

A Phase I/II Trial of the Kinesin Spindle Protein (KSP) Inhibitor SB-743921 Dosed Q14D without and with Prophylactic G-CSF in Non-Hodgkin (NHL) or Hodgkin Lymphoma (HL).

Owen A O'Connor, J. Gerecitano, H. Van Deventer, B. Afanasyev, J. Hainsworth, M. Chen, K. Saikali, J. Seroogy, R. Escandon, A. Wolff, MG. Conlan
Journal: Blood
Blood (2009) 114 (22): 1673.
https://doi.org/10.1182/blood.V114.22.1673.1673
Published: 2009
Journal Articles

A Phase I/II Trial of the Kinesin Spindle Protein (KSP) Inhibitor SB- 743921 Administered on Days 1 and 15 Every 28 Days without and with Prophylactic G-CSF in Non-Hodgkin or Hodgkin Lymphoma.

John Gerecitano, O. O’Connor, H. Van Deventer, J. Hainsworth, J. Leonard, A. Goy, B. Afanasyev, M. Chen, K. Saikali, M. G Conlan, R Escandon, A Wolff
Journal: Blood
Blood (2008) 112 (11): 1563.
https://doi.org/10.1182/blood.V112.11.1563.1563
Published: 2008
Journal Articles

YRRL motifs in the cytoplasmic domain of the thrombopoietin receptor regulate receptor internalization and degradation

Ian S. Hitchcock, Maximus M. Chen, Jennifer R. King, Kenneth Kaushansky
Journal: Blood
Blood (2008) 112 (6): 2222–2231.
https://doi.org/10.1182/blood-2008-01-134049
Published: 2008