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Journal Articles

The hepatokine FGL1 regulates hepcidin and iron metabolism during anemia in mice by antagonizing BMP signaling

Ugo Sardo, Prunelle Perrier, Kevin Cormier, Manon Sotin, Jean Personnaz, Thanina Medjbeur, Aurore Desquesnes, Lisa Cannizzo, Marc Ruiz-Martinez, Julie Thevenin, Benjamin Billoré, Grace Jung, Elise Abboud, Carole Peyssonnaux, Elizabeta Nemeth, Yelena Z. Ginzburg, Tomas Ganz, Léon Kautz

Blood (2024) 143 (13): 1282–1292.

https://doi.org/10.1182/blood.2023022724

Published: 2024

Includes: Supplemental data

Journal Articles

A fully human anti-BMP6 antibody reduces the need for erythropoietin in rodent models of the anemia of chronic disease

Blood (2020) 136 (9): 1080–1090.

https://doi.org/10.1182/blood.2019004653

Published: 2020

Includes: Supplemental data

Journal Articles

Immunoassay for human serum erythroferrone

Tomas Ganz, Grace Jung, Arash Naeim, Yelena Ginzburg, Zahra Pakbaz, Patrick B. Walter, Léon Kautz, Elizabeta Nemeth

Blood (2017) 130 (10): 1243–1246.

https://doi.org/10.1182/blood-2017-04-777987

Published: 2017

Includes: Supplemental data

Journal Articles

Erythroferrone Regulates Hepcidin Expression Independently of Matriptase 2

Leon Kautz, PhD, Sharraya Aschemeyer, Victoria Gabayan, Tomas Ganz, PhD MD, Elizabeta Nemeth, PhD

Blood (2016) 128 (22): 3616.

https://doi.org/10.1182/blood.V128.22.3616.3616

Published: 2016

Journal Articles

Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia

Léon Kautz, Grace Jung, Xin Du, Victoria Gabayan, Justin Chapman, Marc Nasoff, Elizabeta Nemeth, Tomas Ganz

Blood (2015) 126 (17): 2031–2037.

https://doi.org/10.1182/blood-2015-07-658419

Published: 2015

Includes: Supplemental data

Journal Articles

Erythroferrone Represses Hepcidin Expression in a Mouse Model of Malaria

Leon Kautz, PhD, Chloe Latour, Wlodarczyk Myriam, PhD, Nicolas Blanchard, Tomas Ganz, MD PhD, Marie Paule Roth, MD, Helene Coppin, PhD

Blood (2014) 124 (21): 4022.

https://doi.org/10.1182/blood.V124.21.4022.4022

Published: 2014

Journal Articles

Erythron to the Liver: Send Iron

Elizabeta Nemeth, PhD, Tomas Ganz, MD PhD, Léon Kautz, PhD

Blood (2014) 124 (21): SCI-37.

https://doi.org/10.1182/blood.V124.21.SCI-37.SCI-37

Published: 2014

Journal Articles

Role of Erythroferrone in the Pathophysiology of Common Anemias

Leon Kautz, PhD, Grace Jung, MS, Elizabeta Nemeth, PhD, Tomas Ganz, MD PhD

Blood (2014) 124 (21): 213.

https://doi.org/10.1182/blood.V124.21.213.213

Published: 2014

Journal Articles

Erythroferrone contributes to recovery from anemia of inflammation

Léon Kautz, Grace Jung, Elizabeta Nemeth, Tomas Ganz

Blood (2014) 124 (16): 2569–2574.

https://doi.org/10.1182/blood-2014-06-584607

Published: 2014

Includes: Supplemental data

Journal Articles

Molecular liaisons between erythropoiesis and iron metabolism

Leon Kautz, Elizabeta Nemeth

Blood (2014) 124 (4): 479–482.

https://doi.org/10.1182/blood-2014-05-516252

Published: 2014

Journal Articles

The Erythroid Factor Erythroferrone and Its Role In Iron Homeostasis

Léon Kautz, PhD, Grace Jung, MS, Elizabeta Nemeth, PhD, Tomas Ganz, MD, PhD

Blood (2013) 122 (21): 4.

https://doi.org/10.1182/blood.V122.21.4.4

Published: 2013

Journal Articles

Inactivating Hfe Totally Abolishes Hepcidin Production and Further Aggravates Iron Overload In Bmp6-Deficient Mice

Chloe Latour, Celine Besson-Fournier, Nelly Rouquie, Léon Kautz, PhD, Patricia Aguilar-Martinez, Marie-Paule Roth, MD, Helene Coppin

Blood (2013) 122 (21): 178.

https://doi.org/10.1182/blood.V122.21.178.178

Published: 2013

Journal Articles

Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis

Emilio Ramos, Piotr Ruchala, Julia B. Goodnough, Léon Kautz, Gloria C. Preza, Elizabeta Nemeth, Tomas Ganz

Blood (2012) 120 (18): 3829–3836.

https://doi.org/10.1182/blood-2012-07-440743

Published: 2012

Includes: Supplemental data

Journal Articles

Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling

Céline Besson-Fournier, Chloé Latour, Léon Kautz, Jessica Bertrand, Tomas Ganz, Marie-Paule Roth, Hélène Coppin

Blood (2012) 120 (2): 431–439.

https://doi.org/10.1182/blood-2012-02-411470

Published: 2012

Includes: Supplemental data

Journal Articles

Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6

Anne Lenoir, Jean-Christophe Deschemin, Léon Kautz, Andrew J. Ramsay, Marie-Paule Roth, Carlos Lopez-Otin, Sophie Vaulont, Gaël Nicolas

Blood (2011) 117 (2): 647–650.

https://doi.org/10.1182/blood-2010-07-295147

Published: 2011

Journal Articles

BMP/Smad signaling is not enhanced in Hfe -deficient mice despite increased Bmp6 expression

Léon Kautz, Delphine Meynard, Céline Besson-Fournier, Valérie Darnaud, Talal Al Saati, Hélène Coppin, Marie-Paule Roth

Blood (2009) 114 (12): 2515–2520.

https://doi.org/10.1182/blood-2009-02-206771

Published: 2009

Includes: Supplemental data

Journal Articles

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1 , and Atoh8 in the mouse liver

Léon Kautz, Delphine Meynard, Annabelle Monnier, Valérie Darnaud, Régis Bouvet, Rui-Hong Wang, Chiuxia Deng, Sophie Vaulont, Jean Mosser, Hélène Coppin, Marie-Paule Roth

Blood (2008) 112 (4): 1503–1509.

https://doi.org/10.1182/blood-2008-03-143354

Published: 2008

Includes: Supplemental data

NARROW

The hepatokine FGL1 regulates hepcidin and iron metabolism during anemia in mice by antagonizing BMP signaling

A fully human anti-BMP6 antibody reduces the need for erythropoietin in rodent models of the anemia of chronic disease

Immunoassay for human serum erythroferrone

Erythroferrone Regulates Hepcidin Expression Independently of Matriptase 2

Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia

Erythroferrone Represses Hepcidin Expression in a Mouse Model of Malaria

Erythron to the Liver: Send Iron

Role of Erythroferrone in the Pathophysiology of Common Anemias

Erythroferrone contributes to recovery from anemia of inflammation

Molecular liaisons between erythropoiesis and iron metabolism

The Erythroid Factor Erythroferrone and Its Role In Iron Homeostasis

Inactivating Hfe Totally Abolishes Hepcidin Production and Further Aggravates Iron Overload In Bmp6-Deficient Mice

Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis

Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling

Iron-deficiency anemia from matriptase-2 inactivation is dependent on the presence of functional Bmp6

BMP/Smad signaling is not enhanced in Hfe -deficient mice despite increased Bmp6 expression

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1 , and Atoh8 in the mouse liver

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American Society of Hematology

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ASH Publications

American Society of Hematology

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