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Manfred Nairz
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Journal Articles

A fully human anti-BMP6 antibody reduces the need for erythropoietin in rodent models of the anemia of chronic disease

Verena Petzer, Piotr Tymoszuk, Malte Asshoff, Joana Carvalho, Jonathan Papworth, Cecilia Deantonio, Luke Bayliss, Matthew Stephen Wake, Markus Seifert, Natascha Brigo, Lara Valente de Souza, Richard Hilbe, Philipp Grubwieser, Egon Demetz, Stefanie Dichtl, Chiara Volani, Sylvia Berger, Felix Böhm, Alexander Hoffmann, Christa Pfeifhofer-Obermair, Laura von Raffay, Sieghart Sopper, Stephanie Arndt, Anja Bosserhoff, Léon Kautz, Prunelle Perrier, Manfred Nairz, Dominik Wolf, Guenter Weiss, Volker Germaschewski, Igor Theurl
Journal: Blood
Blood (2020) 136 (9): 1080–1090.
https://doi.org/10.1182/blood.2019004653
Published: 2020
Includes: Supplemental data
Journal Articles

Momelotinib inhibits ACVR1/ALK2, decreases hepcidin production, and ameliorates anemia of chronic disease in rodents

Malte Asshoff, Verena Petzer, Matthew R. Warr, David Haschka, Piotr Tymoszuk, Egon Demetz, Markus Seifert, Wilfried Posch, Manfred Nairz, Pat Maciejewski, Peter Fowles, Christopher J. Burns, Gregg Smith, Kay-Uwe Wagner, Guenter Weiss, J. Andrew Whitney, Igor Theurl
Journal: Blood
Blood (2017) 129 (13): 1823–1830.
https://doi.org/10.1182/blood-2016-09-740092
Published: 2017
Includes: Supplemental data
Journal Articles

Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice

Susanna Canali, Kimberly B. Zumbrennen-Bullough, Amanda B. Core, Chia-Yu Wang, Manfred Nairz, Richard Bouley, Filip K. Swirski, Jodie L. Babitt
Journal: Blood
Blood (2017) 129 (4): 405–414.
https://doi.org/10.1182/blood-2016-06-721571
Published: 2017
Includes: Supplemental data
Journal Articles

The Jak1/Jak2 Inhibitor Momelotinib Inhibits Alk2, Decreases Hepcidin Production and Ameliorates Anemia of Chronic Disease (ACD) in Rodents

Malte Asshoff, MD, Matthew Warr, PhD, David Haschka, MD, Piotr Tymoszuk, PhD, Verena Petzer, Egon Demetz, PhD, Pat Maciejewski, PhD, Markus Seifert, Manfred Nairz, MDPhD, Wilfried Posch, PhD, Peter Fowles, Guenter Weiss, MD, Andy Whitney, Igor Theurl, MDPhD
Journal: Blood
Blood (2015) 126 (23): 538.
https://doi.org/10.1182/blood.V126.23.538.538
Published: 2015
Journal Articles

Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats

Igor Theurl, Andrea Schroll, Thomas Sonnweber, Manfred Nairz, Milan Theurl, Wolfgang Willenbacher, Kathrin Eller, Dominik Wolf, Markus Seifert, Chia Chi Sun, Jodie L. Babitt, Charles C. Hong, Tracey Menhall, Patrick Gearing, Herbert Y. Lin, Guenter Weiss
Journal: Blood
Blood (2011) 118 (18): 4977–4984.
https://doi.org/10.1182/blood-2011-03-345066
Published: 2011
Includes: Supplemental data
Journal Articles

Absence of functional Hfe protects mice from invasive Salmonella enterica Serovar Typhimurium infection via induction of lipocalin-2

Manfred Nairz, Igor Theurl, Andrea Schroll, Milan Theurl, Gernot Fritsche, Ewald Lindner, Markus Seifert, Marie-Laure V. Crouch, Klaus Hantke, Shizuo Akira, Ferric C. Fang, Günter Weiss
Journal: Blood
Blood (2009) 114 (17): 3642–3651.
https://doi.org/10.1182/blood-2009-05-223354
Published: 2009
Includes: Supplemental data
Journal Articles

Regulation of iron homeostasis in anemia of chronic disease and iron deficiency anemia: diagnostic and therapeutic implications

Igor Theurl, Elmar Aigner, Milan Theurl, Manfred Nairz, Markus Seifert, Andrea Schroll, Thomas Sonnweber, Lukas Eberwein, Derrick R. Witcher, Anthony T. Murphy, Victor J. Wroblewski, Eva Wurz, Christian Datz, Guenter Weiss
Journal: Blood
Blood (2009) 113 (21): 5277–5286.
https://doi.org/10.1182/blood-2008-12-195651
Published: 2009
Includes: Supplemental data
Journal Articles

Autocrine formation of hepcidin induces iron retention in human monocytes

Igor Theurl, Milan Theurl, Markus Seifert, Sabine Mair, Manfred Nairz, Holger Rumpold, Heinz Zoller, Rosa Bellmann-Weiler, Harald Niederegger, Heribert Talasz, Günter Weiss
Journal: Blood
Blood (2008) 111 (4): 2392–2399.
https://doi.org/10.1182/blood-2007-05-090019
Published: 2008