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Journal Articles

Inflammation-Driven NFκB Signaling Represses Ferroportin Transcription in Macrophages Via HDAC 1 and 3

Oriana Marques, Natalie Horvat, Laura Zechner, Silvia Colucci, Richard Sparla, Stefan Zimmermann, Christopher Neufeldt, Sandro Altamura, Qiu Ruiyue, Katja Müdder, Guenter Weiss, Matthias Hentze, Martina U. Muckenthaler
Journal: Blood
Blood (2024) 144 (Supplement 1): 9.
https://doi.org/10.1182/blood-2024-210131
Published: 2024
Journal Articles

A fully human anti-BMP6 antibody reduces the need for erythropoietin in rodent models of the anemia of chronic disease

Verena Petzer, Piotr Tymoszuk, Malte Asshoff, Joana Carvalho, Jonathan Papworth, Cecilia Deantonio, Luke Bayliss, Matthew Stephen Wake, Markus Seifert, Natascha Brigo, Lara Valente de Souza, Richard Hilbe, Philipp Grubwieser, Egon Demetz, Stefanie Dichtl, Chiara Volani, Sylvia Berger, Felix Böhm, Alexander Hoffmann, Christa Pfeifhofer-Obermair, Laura von Raffay, Sieghart Sopper, Stephanie Arndt, Anja Bosserhoff, Léon Kautz, Prunelle Perrier, Manfred Nairz, Dominik Wolf, Guenter Weiss, Volker Germaschewski, Igor Theurl
Journal: Blood
Blood (2020) 136 (9): 1080–1090.
https://doi.org/10.1182/blood.2019004653
Published: 2020
Includes: Supplemental data
Journal Articles

Anemia of inflammation

Clinical Trials & Observations
Guenter Weiss, Tomas Ganz, Lawrence T. Goodnough
Journal: Blood
Blood (2019) 133 (1): 40–50.
https://doi.org/10.1182/blood-2018-06-856500
Published: 2019
Journal Articles

Momelotinib inhibits ACVR1/ALK2, decreases hepcidin production, and ameliorates anemia of chronic disease in rodents

Malte Asshoff, Verena Petzer, Matthew R. Warr, David Haschka, Piotr Tymoszuk, Egon Demetz, Markus Seifert, Wilfried Posch, Manfred Nairz, Pat Maciejewski, Peter Fowles, Christopher J. Burns, Gregg Smith, Kay-Uwe Wagner, Guenter Weiss, J. Andrew Whitney, Igor Theurl
Journal: Blood
Blood (2017) 129 (13): 1823–1830.
https://doi.org/10.1182/blood-2016-09-740092
Published: 2017
Includes: Supplemental data
Journal Articles

Preclinical Modeling of ACVR1-Dependent Hepcidin Production and Anemia By Momelotinib

Matthew Warr, Malte Asshoff, Jim Zheng, Shringi Sharma, Pat Maciejewski, Guenter Weiss, Igor Theurl, J. Andrew Whitney
Journal: Blood
Blood (2016) 128 (22): 1967.
https://doi.org/10.1182/blood.V128.22.1967.1967
Published: 2016
Journal Articles

The Jak1/Jak2 Inhibitor Momelotinib Inhibits Alk2, Decreases Hepcidin Production and Ameliorates Anemia of Chronic Disease (ACD) in Rodents

Malte Asshoff, MD, Matthew Warr, PhD, David Haschka, MD, Piotr Tymoszuk, PhD, Verena Petzer, Egon Demetz, PhD, Pat Maciejewski, PhD, Markus Seifert, Manfred Nairz, MDPhD, Wilfried Posch, PhD, Peter Fowles, Guenter Weiss, MD, Andy Whitney, Igor Theurl, MDPhD
Journal: Blood
Blood (2015) 126 (23): 538.
https://doi.org/10.1182/blood.V126.23.538.538
Published: 2015
Journal Articles

Inflammatory and Vitamin Bio-Markers Of Iron Trafficking and Distribution In Transfusional Overload: Insights From Comparing Diamond Blackfan Anemia With Sickle Cell Disease and Thalassemia (MCSIO PILOT Study)

John Porter, MD, Patrick B Walter, PhD, Lynne D Neumayr, MD, Patricia Evans, PhD, Marcela G Weyhmiller, PhD, Paul Harmatz, MD, John C. Wood, MD, PhD, Jeffery L Miller, MD, Guenter Weiss, MD, Quing Yuan, PhD, Zhiyue J Wang, PhD, Regine Grosse, MD, Bjoern P Schoennagel, MD, Joerg Meerpohl, MD, Roland Fischer, PhD, Peter Nielsen, MD, Markus Seifert, BSc, Elliott Vichinsky, MD
Journal: Blood
Blood (2013) 122 (21): 1014.
https://doi.org/10.1182/blood.V122.21.1014.1014
Published: 2013
Journal Articles

Iron Trafficking and Distribution in Transfusional Overload: Insights From Comparing Diamond Blackfan Anemia with Sickle Cell Disease and Thalassemia

John B. Porter, MD, Patrick B Walter, PhD, Lynne D Neumayr, MD, Patricia Evans, PhD, Marcela G Weyhmiller, PhD, Paul Harmatz, MD, John C Wood, MD, Ph.D, Jeffery L. Miller, Guenter Weiss, MD, Qing Yuan, Zhiyue J Wang, Regine Grosse, MD, Bjoern P Schoennagel, Joerg Meerpohl, Roland Fischer, PhD, Elliott Vichinsky, MD
Journal: Blood
Blood (2012) 120 (21): 995.
https://doi.org/10.1182/blood.V120.21.995.995
Published: 2012
Journal Articles

Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats

Igor Theurl, Andrea Schroll, Thomas Sonnweber, Manfred Nairz, Milan Theurl, Wolfgang Willenbacher, Kathrin Eller, Dominik Wolf, Markus Seifert, Chia Chi Sun, Jodie L. Babitt, Charles C. Hong, Tracey Menhall, Patrick Gearing, Herbert Y. Lin, Guenter Weiss
Journal: Blood
Blood (2011) 118 (18): 4977–4984.
https://doi.org/10.1182/blood-2011-03-345066
Published: 2011
Includes: Supplemental data
Journal Articles

Regulation of iron homeostasis in anemia of chronic disease and iron deficiency anemia: diagnostic and therapeutic implications

Igor Theurl, Elmar Aigner, Milan Theurl, Manfred Nairz, Markus Seifert, Andrea Schroll, Thomas Sonnweber, Lukas Eberwein, Derrick R. Witcher, Anthony T. Murphy, Victor J. Wroblewski, Eva Wurz, Christian Datz, Guenter Weiss
Journal: Blood
Blood (2009) 113 (21): 5277–5286.
https://doi.org/10.1182/blood-2008-12-195651
Published: 2009
Includes: Supplemental data
Journal Articles

Response: Monocyte hepcidin and the anemia of chronic disease

Guenter Weiss, Igor Theurl
Journal: Blood
Blood (2008) 111 (7): 3902–3903.
https://doi.org/10.1182/blood-2008-01-134163
Published: 2008
Journal Articles

Altered Immune Response in Severe Malaria Anemia in Children.

Victor R. Gordeuk, MD, Ishmael Kasvosve, PhD, Janneke van Dijk, MD, Guenter Weiss, MD, Zufan Debebe, MS, Sergei Nekhai, PhD, Thea Kuddo, MD, Philip E. Thuma, MD
Journal: Blood
Blood (2006) 108 (11): 1303.
https://doi.org/10.1182/blood.V108.11.1303.1303
Published: 2006