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Journal Articles

Monocytic Leukemia Cell Resistance to Ferroptosis Is Overcome By Iron Chelation

Zachariah A.H. Fenniri, Sarah Lane, Juergen Ehlting, Patrick B Walter

Blood (2024) 144 (Supplement 1): 7468.

https://doi.org/10.1182/blood-2024-211689

Published: 2024

Journal Articles

Increased Environmental Temperature Damages DNA and Is an Emerging Health Risk That Correlates with Rates of Acute Lymphoblastic Leukemia (ALL) in Europe

Serena Jilani, Risha Rohilla, Helen Ross, Clayton Craig, Daniel Brendle-Moczuk, Juergen Ehlting, Mark Lewis, Patrick B Walter

Blood (2024) 144 (Supplement 1): 1430.

https://doi.org/10.1182/blood-2024-211538

Published: 2024

Journal Articles

Iron-Chelating Potential of Novel Phytochemicals in Poplar and Cedar Trees

Sarah Lane, BSc, Juergen Ehlting, MSc, PhD, Patrick B Walter, MSc, PhD

Blood (2019) 134 (Supplement_1): 4806.

https://doi.org/10.1182/blood-2019-127259

Published: 2019

Journal Articles

The Potential of Plant-Based Compounds As Iron Chelators

Sarah Lane, Farzam Viand, Kayla Bolduc, Juergen Ehlting, MSc, PhD, Patrick B Walter, MSc, PhD

Blood (2018) 132 (Supplement 1): 3631.

https://doi.org/10.1182/blood-2018-99-117528

Published: 2018

Journal Articles

Isolation and Chelation Activity of Plant Phenolic Root Exudates As Potential Clinical Iron Chelators

Sarah Lane, Maia Skowron, BSc, Alixandra Wong, BSc, Kevin Yongblah, MSc, Jürgen Ehlting, MSc, PhD, Patrick B Walter, MSc, PhD

Blood (2017) 130 (Supplement 1): 3505.

https://doi.org/10.1182/blood.V130.Suppl_1.3505.3505

Published: 2017

Journal Articles

Systemic Biomarkers Show Elevated Oxidative Stress and Chronic Inflammation in Two Disorders of Neurodegeneration with Brain Iron Accumulation (NBIA)

Michael Minkley, BSc, Nancy Sweeters, PNP, Shiva Kasravi, BS, Jennifer Ferguson, BS MS, Annie Higa, BS, Angela Jackson, BSc MSc, Derek Smith, BS MS, Christoph Borchers, PhD, Raad Nashmi, PhD, Patrick Macleod, MD, Lynne D. Neumayr, MD, Elliott Vichinsky, MD, Patrick B Walter, MSc, PhD

Blood (2017) 130 (Supplement 1): 943.

https://doi.org/10.1182/blood.V130.Suppl_1.943.943

Published: 2017

Journal Articles

Immunoassay for human serum erythroferrone

Tomas Ganz, Grace Jung, Arash Naeim, Yelena Ginzburg, Zahra Pakbaz, Patrick B. Walter, Léon Kautz, Elizabeta Nemeth

Blood (2017) 130 (10): 1243–1246.

https://doi.org/10.1182/blood-2017-04-777987

Published: 2017

Includes: Supplemental data

Journal Articles

Implications of Low Zinc and Copper Levels As Well As Altered Iron Trafficking Proteins on Oxidant Stress in Patients with Transfusion Dependant Thalassemia

Patrick B Walter, PhD, Michael Minkley, BS, Caitlin Curtis, BS, Hodge Maeve, BS, Razavi Morty, PhD, Sarah Ewing, BS, Ashutosh Lal, MD, Anne Higa, BS, David Killilea, PhD, Terry Pearson, PhD, Ellen B. Fung, PhD RD, CCD

Blood (2016) 128 (22): 1289.

https://doi.org/10.1182/blood.V128.22.1289.1289

Published: 2016

Journal Articles

The Effects of Glutamine Supplementation on Markers of Autophagy and Apoptosis in Peripheral Blood Mononuclear Cells from Patients with Sickle Cell Disease

Patrick B Walter, PhD, Leah Hohman, BS, Andrew Rokeby, BS, Julian Lum, PhD, Robert Hagar, MD, Melinee Stewart, BS, Lisa Lavrisha, BS, Elliott Vichinsky, MD, Claudia R. Morris, MD

Blood (2015) 126 (23): 3412.

https://doi.org/10.1182/blood.V126.23.3412.3412

Published: 2015

Journal Articles

Iron Level and Monocyte Morphology Predict TLR4 Expression and Reactive Oxygen Species Production Which Influences Chronic Inflammation in β-Thalassemia

Patrick B. Walter, PhD, Nick Slater, BS, Paul Harmatz, MD, Annie Higa, BS, Vivian Ng, BS, Marcels Weyhmiller, Patricia Evans, PhD, John B Porter, Nancy Sweeters, Jackson Price, BS, David Killilea, PhD, Lynne Neumayr, MD, Ashutosh Lal, MD, Elliott Vichinsky, MD

Blood (2015) 126 (23): 950.

https://doi.org/10.1182/blood.V126.23.950.950

Published: 2015

Journal Articles

Association Of Cardiac Iron By T2* With Innate Immune Markers In Transfusion-Dependent Thalassemia Patients Undergoing Combined Chelation Therapy

Patrick B Walter, PhD, Annie Higa, BS, Vivian Ng, B.S., Marcela G Weyhmiller, PhD, Nick R Slater, Patricia Evans, PhD, John B Porter, MD, Nancy Sweeters, RN, PNP, Jackson Price, B.S., Alisha Manji, B.S., David Killilea, PhD, Ashutosh Lal, MD, Elliott Vichinsky, MD

Blood (2013) 122 (21): 3450.

https://doi.org/10.1182/blood.V122.21.3450.3450

Published: 2013

Journal Articles

Determinants Of Tissue Iron Loading In Transfused and Non-Transfused β-Thalassemia and Sickle Cell Disease Patients – Biomarkers Of Iron Regulation and Inflammation

Patrick B Walter, PhD, Zahra Pakbaz, MD, Elizabeta Nemeth, PhD, Tomas Ganz, MD, PhD, John B Porter, MD, Patricia Evans, PhD, Kelsey M Houston, Roland Fischer, PhD, Marcela G Weyhmiller, PhD, Matt Herz, Bs, Jeffery L Miller, MD, Robert Hagar, MD, Lynne D Neumayr, MD, Elliott Vichinsky, MD, Paul Harmatz, MD

Blood (2013) 122 (21): 1017.

https://doi.org/10.1182/blood.V122.21.1017.1017

Published: 2013

Journal Articles

Inflammatory and Vitamin Bio-Markers Of Iron Trafficking and Distribution In Transfusional Overload: Insights From Comparing Diamond Blackfan Anemia With Sickle Cell Disease and Thalassemia (MCSIO PILOT Study)

John Porter, MD, Patrick B Walter, PhD, Lynne D Neumayr, MD, Patricia Evans, PhD, Marcela G Weyhmiller, PhD, Paul Harmatz, MD, John C. Wood, MD, PhD, Jeffery L Miller, MD, Guenter Weiss, MD, Quing Yuan, PhD, Zhiyue J Wang, PhD, Regine Grosse, MD, Bjoern P Schoennagel, MD, Joerg Meerpohl, MD, Roland Fischer, PhD, Peter Nielsen, MD, Markus Seifert, BSc, Elliott Vichinsky, MD

Blood (2013) 122 (21): 1014.

https://doi.org/10.1182/blood.V122.21.1014.1014

Published: 2013

Journal Articles

Innate Immune Cell Expression of Pattern Recognition Receptors From β-Thalassemia Patients During Intensive Combination Chelation Therapy

Patrick B Walter, PhD, Paul Harmatz, MD, Annie Higa, B.S., Vivian Ng, B.S., Marcela G Weyhmiller, PhD, Patricia Evans, PhD, John B. Porter, MD, Nancy Sweeters, RN, PNP, Jackson Price, B.S., Alisha Manji, B.S., David Killilea, PhD, Ashutosh Lal, MD, Elliott Vichinsky, MD

Blood (2012) 120 (21): 1025.

https://doi.org/10.1182/blood.V120.21.1025.1025

Published: 2012

Journal Articles

Iron Trafficking and Distribution in Transfusional Overload: Insights From Comparing Diamond Blackfan Anemia with Sickle Cell Disease and Thalassemia

John B. Porter, MD, Patrick B Walter, PhD, Lynne D Neumayr, MD, Patricia Evans, PhD, Marcela G Weyhmiller, PhD, Paul Harmatz, MD, John C Wood, MD, Ph.D, Jeffery L. Miller, Guenter Weiss, MD, Qing Yuan, Zhiyue J Wang, Regine Grosse, MD, Bjoern P Schoennagel, Joerg Meerpohl, Roland Fischer, PhD, Elliott Vichinsky, MD

Blood (2012) 120 (21): 995.

https://doi.org/10.1182/blood.V120.21.995.995

Published: 2012

Journal Articles

Iron Overload Diminishes the Effectiveness of the Innate Immune Response in Thalassemia Major: a Possible Mechanism for Increased Infection Risk.

Patrick B Walter, PhD, Paul R Harmatz, Annie Higa, B.S., David Killilea, PhD, Nancy Sweeters, RN, PNP, Elliott P Vichinsky, MD

Blood (2009) 114 (22): 4071.

https://doi.org/10.1182/blood.V114.22.4071.4071

Published: 2009

Journal Articles

Increased Nucleosomal DNA Fragmentation in Leukocytes of Thalassemia Patients.

Patrick B Walter, PhD, John B Porter, MD, Patricia Evans, PhD, Janet Kwiatkowski, MD, Ellis J. Neufeld, MD, PhD, Thomas D. Coates, MD, Patricia Giardina, MD, Robert jW Grady, PhD, Elliott Vichinsky, MD, Nancy F. Olivieri, MD, Felicia Trachtenberg, PhD, Daniele Alberti, MD, Ellen Fung, PhD, Bruce Ames, PhD, Annie Lui, BS, Paul Harmatz, MD

Blood (2008) 112 (11): 1868.

https://doi.org/10.1182/blood.V112.11.1868.1868

Published: 2008

Journal Articles

Leukocyte Apoptosis and Mitochondrial Dysfunction in β-Thalassemia Patients Treated with Deferasirox or Deferoxamine.

Patrick B. Walter, PhD, John Porter, MD, Patricia Evans, PhD, Janet L. Kwiatkowski, MD, Ellis J. Neufeld, MD, Thomas Coates, MD, Patricia J. Giardina, MD, Robert W. Grady, PhD, Elliott Vichinsky, MD, Nancy F. Olivieri, MD, Felicia Trachtenberg, PhD, Daniele Alberti, MD, Jaymes Holland, PhD, Ellen Fung, PhD, Bruce Ames, PhD, Annie Lui, BS, Paul Harmatz, MD

Blood (2007) 110 (11): 2773.

https://doi.org/10.1182/blood.V110.11.2773.2773

Published: 2007

Journal Articles

Leukocyte Apoptosis and Inflammation in Iron-Overloaded Patients with Sickle Cell Disease or β-Thalassemia: A Mechanism for Increased Stroke and Disease Severity in Sickle Cell Disease.

Patrick B. Walter, PhD, David W. Killilea, PhD, Ellen B. Fung, PhD, Annie Lui, BS, Jacqueline Madden, PNP, John Porter, MD, Patricia Evans, PhD, Bruce N. Ames, PhD, Elliott Vichinsky, MD, Paul Harmatz, MD

Blood (2006) 108 (11): 1233.

https://doi.org/10.1182/blood.V108.11.1233.1233

Published: 2006

Journal Articles

Toxic Unbound Iron and Membrane Injury in b-Thalassemia and Sickle Cell Disease: Elevated Non-Transferrin Bound Iron (NTBI) and Malondialdehyde (MDA).

Patrick B. Walter, PhD, Ellen Fung, PhD, David W. Killilea, PhD, Qing Jiang, PhD, Bruce N. Ames, PhD, Jacqueline Madden, PNP, Ellen Butensky, PhD, John Porter, MD, Patricia Evans, PhD, Paul Harmatz, MD, Elliott P. Vichinsky, MD

Blood (2004) 104 (11): 3608.

https://doi.org/10.1182/blood.V104.11.3608.3608

Published: 2004

NARROW

Monocytic Leukemia Cell Resistance to Ferroptosis Is Overcome By Iron Chelation

Increased Environmental Temperature Damages DNA and Is an Emerging Health Risk That Correlates with Rates of Acute Lymphoblastic Leukemia (ALL) in Europe

Iron-Chelating Potential of Novel Phytochemicals in Poplar and Cedar Trees

The Potential of Plant-Based Compounds As Iron Chelators

Isolation and Chelation Activity of Plant Phenolic Root Exudates As Potential Clinical Iron Chelators

Systemic Biomarkers Show Elevated Oxidative Stress and Chronic Inflammation in Two Disorders of Neurodegeneration with Brain Iron Accumulation (NBIA)

Immunoassay for human serum erythroferrone

Implications of Low Zinc and Copper Levels As Well As Altered Iron Trafficking Proteins on Oxidant Stress in Patients with Transfusion Dependant Thalassemia

The Effects of Glutamine Supplementation on Markers of Autophagy and Apoptosis in Peripheral Blood Mononuclear Cells from Patients with Sickle Cell Disease

Iron Level and Monocyte Morphology Predict TLR4 Expression and Reactive Oxygen Species Production Which Influences Chronic Inflammation in β-Thalassemia

Association Of Cardiac Iron By T2* With Innate Immune Markers In Transfusion-Dependent Thalassemia Patients Undergoing Combined Chelation Therapy

Determinants Of Tissue Iron Loading In Transfused and Non-Transfused β-Thalassemia and Sickle Cell Disease Patients – Biomarkers Of Iron Regulation and Inflammation

Inflammatory and Vitamin Bio-Markers Of Iron Trafficking and Distribution In Transfusional Overload: Insights From Comparing Diamond Blackfan Anemia With Sickle Cell Disease and Thalassemia (MCSIO PILOT Study)

Innate Immune Cell Expression of Pattern Recognition Receptors From β-Thalassemia Patients During Intensive Combination Chelation Therapy

Iron Trafficking and Distribution in Transfusional Overload: Insights From Comparing Diamond Blackfan Anemia with Sickle Cell Disease and Thalassemia

Iron Overload Diminishes the Effectiveness of the Innate Immune Response in Thalassemia Major: a Possible Mechanism for Increased Infection Risk.

Increased Nucleosomal DNA Fragmentation in Leukocytes of Thalassemia Patients.

Leukocyte Apoptosis and Mitochondrial Dysfunction in β-Thalassemia Patients Treated with Deferasirox or Deferoxamine.

Leukocyte Apoptosis and Inflammation in Iron-Overloaded Patients with Sickle Cell Disease or β-Thalassemia: A Mechanism for Increased Stroke and Disease Severity in Sickle Cell Disease.

Toxic Unbound Iron and Membrane Injury in b-Thalassemia and Sickle Cell Disease: Elevated Non-Transferrin Bound Iron (NTBI) and Malondialdehyde (MDA).

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American Society of Hematology

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American Society of Hematology

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