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Journal Articles

Enhancer Hijacking of BCL11B Defines a Subtype of Lineage Ambiguous Acute Leukemia

Free
Lindsey Montefiori, PhD, Sonja Seliger, MS, Zhaohui Gu, PhD, Xiaotu Ma, PhD, Beisi Xu, PhD, Xiaolong Chen, PhD, Kirsten Dickerson, BS, Tamara Westover, BS, Anna Stengel, PhD, Ilaria Iacobucci, PhD, Shunsuke Kimura, MD PhD, Chunxu Qu, PhD, Jing Ma, PhD, Marc Valentine, BA, Wolfgang Kern, MD, Torsten Haferlach, MD, Gang Wu, PhD, Jeffery M. Klco, MD PhD, Claudia Haferlach, MD, Charles G Mullighan, MBBS, MD
Journal: Blood
Blood (2020) 136 (Supplement_2): LBA-3.
https://doi.org/10.1182/blood-2020-143881
Published: 2020
Journal Articles

TRAF3 Loss Drives Alternative NF-κB Pathway Activation in Diffuse Large B-Cell Lymphoma

Free
Michael Y. Li, BS, Lauren C. Chong, MSc, Elizabeth Chavez, BSc, Cg RT, Bruce W Woolcock, Adele Telenius, Vivian Lam, Gerald Krystal, PhD, David W. Scott, MBChB, PhD, Elena Viganò, PhD, Shannon Healy, PhD, Christian Steidl, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 22–23.
https://doi.org/10.1182/blood-2020-141126
Published: 2020
Journal Articles

Impact of Comorbidities on Outcomes of Peripheral T Cell Lymphoma in Elderly Patients: An International Retrospective Study

Free
Monica Mead, MD BS, Henrik Cederleuf, MD, Thomas Relander, MD PhD, Mats Jerkeman, MD PhD, Fredrik Ellin, MD PhD, Daria Gaut, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 27–28.
https://doi.org/10.1182/blood-2020-134814
Published: 2020
Journal Articles

Xeno-MCL: Genomic, Transcriptomic and Pathologic Landscape Associated with Disease Progression, Clonal Evolution and Tissue Tropism in Patient-Derived Xenografts of Mantle Cell Lymphoma

Free
Vivian Changying Jiang, PhD, Shaojun Zhang, PhD, Shuangtao Zhao, PhD, Yang Liu, PhD, Joseph McIntosh, BS, Linghua Wang, MDPhDMS, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 20.
https://doi.org/10.1182/blood-2020-140878
Published: 2020
Journal Articles

Global Transcriptional States of Follicular Lymphoma B Cells Highlight Distinct Groups of Tumor Identity Associated with Somatic Alterations and Tumor Microenvironment

Free
Jordan Krull, BS, Kerstin Wenzl, PhD, Michelle Manske, MS, BS, Melissa Hopper, MSc, Melissa C. Larson, MS, Vivekananda Sarangi, Matthew J. Maurer, MS, Zhi-Zhang Yang, PhD, Lisa M. Rimsza, MD, Brian K. Link, MD, Thomas M. Habermann, MD, Stephen M. Ansell, MD PhD, Rebecca L. King, MD, James R. Cerhan, MD PhD, Anne J. Novak, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 21–22.
https://doi.org/10.1182/blood-2020-142744
Published: 2020
Journal Articles

Combination of Ibrutinib with Rituximab (IR) in Previously Untreated Older Patients with Mantle Cell Lymphoma (MCL) - a Phase II Clinical Trial

Free
Preetesh Jain, MBBS,MDDM,PhD, Yixin Yao, PhD, Shuangtao Zhao, PhD, Yang Liu, PhD, Holly Hill, Yuxuan Che, Yijing Li, MS, Alexa A Jordan, BS, Joseph McIntosh, BS, Hun Ju Lee, MD, Raphael Eric Steiner, MD, Felipe Samaniego, MD, Jason Westin, MD, Loretta J. Nastoupil, MD, Ranjit Nair, Sairah Ahmed, MD, Chi Young Ok, MD, Rashmi Kanagal-Shamanna, MD, Onyeka Oriabure, Guofang Xu, MD, Wendy Chen, Omar Moghrabi, Chloe Marie McClain, Maria Badillo, MSN, RN, OCN, CCRP, Selvi Thirumurthi, David Santos, Cezar Iliescu, MD, C. Cameron Yin, MD PhD, Shaoying Li, MD, Guilin Tang, MD, Francisco Vega, MDPhD, Sattva S. Neelapu, MD, Christopher Flowers, MDMS, Linghua Wang, PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 41–42.
https://doi.org/10.1182/blood-2020-137167
Published: 2020
Journal Articles

Shifting Treatment Patterns and Clinical Outcomes in Veterans Diagnosed with Waldenstrom Macroglobulinemia from 2006 to 2018

Free
Hsu-Chih Chien, PhD MSc, Deborah Kay Morreall, BS, Vikas Patil, MS, Kelli M Rasmussen, BSc,MS, Christina Yong, MA, Catherine Li, PhD, Zachary R Burningham, PhD, Brian C Sauer, PhD, Ahmad S Halwani, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 12.
https://doi.org/10.1182/blood-2020-141427
Published: 2020
Journal Articles

Long-Term Safety and Efficacy of Orelabrutinib Monotherapy in Chinese Patients with Relapsed or Refractory Mantle Cell Lymphoma: A Multicenter, Open-Label, Phase II Study

Free
Yuqin Song, MD PhD, Yongping Song, MD, Lihong Liu, MD, Mingzhi Zhang, MD, Zhiming Li, MD PhD, Chunyan Ji, MD, Wei Xu, MD PhD, Ting Liu, MD PhD, Bing Xu, MD PhD, Xin Wang, MDPhD, Sujun Gao, Huilai Zhang, MD PhD, Yu Hu, MD, Yan Li, Ying Cheng, Haiyan Yang, MD PhD, Junning Cao, Zunmin Zhu, MD, Jianda Hu, MDPhD, Wei Zhang, Hongmei Jing, MD PhD, Kaiyang Ding, Zhengguang Lu, Bin Zhang, PhD, Renbin Zhao, PhD, Zhixin Xu, MD PhD, Jun Zhu, BS
Journal: Blood
Blood (2020) 136 (Supplement 1): 1.
https://doi.org/10.1182/blood-2020-141781
Published: 2020
Journal Articles

R-Nanochop Incorporating a TFR1-Targeted Doxorubicin Nanocarrier Is Superior to R-CHOP in a PDX Model of Diffuse Large B-Cell Lymphoma

Free
Artavazd Arumov, BSc, Piumi Y. Liyanage, PhD, Asaad Trabolsi, MD, Evan R. Roberts, BS, Braulio C. L. B. Ferreira, BS, Austin D. Newsam, BS, Daniel Bilbao, PhD, Roger M. Leblanc, PhD, Jonathan H. Schatz, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 43.
https://doi.org/10.1182/blood-2020-133482
Published: 2020
Journal Articles

Triple Gene-Modified iPSC-Derived NK Cells Combined with Daratumumab for Targeted Immunotherapy Against AML

Free
Frank Cichocki, PhD, Ryan Bjordahl, PhD, Karrune Woan, MD PhD, Zachary Davis, PhD BS, Greg Bonello, Sajid Mahmood, PhD, Paul Rogers, PhD, Moyar Q. Ge, PhD, Tom Lee, PhD, Martin Felices, PhD, Bruce Walcheck, PhD, Bruce R. Blazar, MD, Bahram Valamehr, PhD, Jeffrey S. Miller, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 57–58.
https://doi.org/10.1182/blood-2020-137138
Published: 2020
Journal Articles

AZD4320 Is a Novel and Potent BCL-2/X L Dual Inhibitor in Targeting Aggressive Mantle Cell Lymphoma

Free
Yijing Li, MS, Yang Liu, PhD, Joseph McIntosh, BS, Alexa A Jordan, BS, Angela Leeming, Courtney L Andersen, PhD, Justin Cidado, PhD, Vivian Changying Jiang, PhD, Michael Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 44.
https://doi.org/10.1182/blood-2020-140775
Published: 2020
Journal Articles

Interim Analysis from a Prospective Multicenter Study of Next-Generation Sequencing Minimal Residual Disease Assessment and CT Monitoring for Surveillance after Frontline Treatment in Diffuse Large B-Cell Lymphoma

Free
Anita Kumar, MD, Jason Westin, MD, Stephen J Schuster, MD, Grzegorz S. Nowakowski, MD, Izidore S. Lossos, MD, Connie Lee Batlevi, MDPhD, Philip Caron, MD PhD, Pamela Drullinsky, MD, John Gerecitano, MD PhD, Audrey Hamilton, MD, Paul A. Hamlin, MD, Steven M. Horwitz, MD, Allison P. Jacob, Erel Joffe, MD MSc, Ashlee Joseph, Gottfried R. von Keudell, MD PhD, Leana Laraque, BA, Oscar B Lahoud, MD, Matthew J Matasar, MD, Craig H. Moskowitz, MD, Chelsea D Mullins, BS, Ariela Noy, MD, Colette Owens, MD, Maria Lia Palomba, Carol S. Portlock, MD, Ildefonso Rodriguez-Rivera, MD, Gilles Salles, MDPhD, Venkatraman Seshan, PhD, David J. Straus, MD, Shreya Vemuri, Anas Younes, Andrew D Zelenetz, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 46–47.
https://doi.org/10.1182/blood-2020-138889
Published: 2020
Journal Articles

Ktx-120, a Novel Irakimid Degrader of IRAK4 and IMiD Substrates Shows Preferential Activity and Induces Regressions in MYD88-Mutant DLBCL CDX and PDX Models

Free
Duncan Walker, PhD, Michele Mayo, Christine Klaus, BS, Dapeng Chen, PhD, Samyabrata Bhaduri, PhD, Kirti Sharma, Scott Rusin, Alice McDonald, PhD, Jared Gollob, PhD MD, Nello Mainolfi, PhD, Matt Weiss, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 41.
https://doi.org/10.1182/blood-2020-137750
Published: 2020
Journal Articles

Metabolically Flexible CAR T Cells (mfCAR-T), with Constitutive Expression of PGC-1α Resistant to Post Translational Modifications, Exhibit Superior Survival and Function in Vitro

Free
Reginald M Atkins, PhD, Meghan A Menges, Alexis Bauer, BS, Joel G. Turner, PhD, Frederick L. Locke, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30.
https://doi.org/10.1182/blood-2020-143217
Published: 2020
Journal Articles

Improved Utilization Amongst Adult Sickle Cell Disease Patients: A Multi-Disciplinary Medical Home Approach

Free
Daniel Sop, BS,MS, Shirley Johnson, BA, LSW, Benjamin Jaworowski, BS, Wally R Smith, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 22–23.
https://doi.org/10.1182/blood-2020-143001
Published: 2020
Journal Articles

Patient Reported Outcomes Among Systemic Mastocytosis (SM) Patients in Routine Clinical Practice: Results from the TouchStone Survey

Free
Ruben A. Mesa, MD FACP, Erin M. Sullivan, PhD, David Dubinsky, MBA, BS, Brittany Carroll, MBA, Valerie M. Slee, RN, BSN, Susan Jennings, PhD, Celeste Finnerty, PhD, Linda Bohannon, RN, BSN, MSM, Susan Mathias, MPH, Mariana Castells, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37.
https://doi.org/10.1182/blood-2020-137480
Published: 2020
Journal Articles

Diabetes Mellitus and Risk of Plasma Cell and Lymphoproliferative Disorders: A Population Based Study Including 94,579 Cases and 368,348 Matched Controls

Free
Urvi A Shah, MD, Sæmundur Rögnvaldsson, BS, Andriy Derkach, PhD, Magnus Björkholm, MD PhD, Ingemar Turesson, MD PhD, Yael David, PhD, Malin Hultcrantz, MD PhD, Carlyn Tan, MD, Hani Hassoun, MD, Neha Korde, MD, Alexander M. Lesokhin, MD, Sham Mailankody, MBBS, Sigurður Yngvi Kristinsson, MD PhD, Ola Landgren, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 44–45.
https://doi.org/10.1182/blood-2020-141597
Published: 2020
Journal Articles

Impaired Sars-Cov-2 Specific Antibody Responses in Patients Treated with Anti-CD20 Antibodies

Free
Alessandra Sottini, BS, Luisa Imberti, MD, Simone Paghera, BS, Vanessa Previcini, BS, Chiara Cattaneo, Eugenia Quiros-Roldan, MD, Ruggero Capra, MD, Giuseppe Rossi, MD, Kerry Dobbs, BS, Elana Shaw, BS, Luigi D. Notarangelo, MD, Peter Burbelo, PhD, Jeffrey Cohen, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 47–48.
https://doi.org/10.1182/blood-2020-141234
Published: 2020
Journal Articles

PD-L1/PD-1 Pattern of Distribution within Bone Marrow Microenvironment Cells in Patients with Smoldering Myeloma and Active Multiple Myeloma

Free
Federica Costa, Rosanna Vescovini, PhD, Laura Notarfranchi, Paola Storti, PhD, Valentina Marchica, MS, Anna Benedetta Dalla Palma, MD, Cristina Manferdini, BS, Denise Toscani, PhD, Rosalba Eufemiese, MS, Jessica Burroughs, PhD, Gina Lisignoli, PhD, Nicola Giuliani
Journal: Blood
Blood (2020) 136 (Supplement 1): 49–50.
https://doi.org/10.1182/blood-2020-139275
Published: 2020
Journal Articles

Gene Body Methylation and Transcriptional Activity in ASXL1-Mutant Chronic Myelomonocytic Leukemia

Free
Moritz Binder, MDMPH, Ryan M. Carr, MD PhD, Terra Lasho, PhD, Christy Finke, BS, Abhishek A. Mangaonkar, MBBS, Christopher Pin, PhD, Kurt Berger, Tamas Ordog, MD, Bonnie Alver, PhD, Keith Robertson, PhD, David Marks, PhD, Martin Fernandez-Zapico, MD, Alexandre Gaspar Maia, PhD, Mrinal M. Patnaik, MDMBBS
Journal: Blood
Blood (2020) 136 (Supplement 1): 31–32.
https://doi.org/10.1182/blood-2020-134964
Published: 2020