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Journal Articles

Clonal Hematopoiesis and Inflammation in the Vasculature (CHIVE), a Prospective, Longitudinal Clonal Hematopoiesis Cohort and Biorepository

Jonathan Heimlich, Morgan Shannon, Sydney Olson, Alexander J Silver, Ariana Debevec, Zachary Copeland, Caitlyn Vlasschaert, Christina Snider, Ashwin Kishtagari, Donovan J Brown, Travis Spaulding, Manasa R Bhatta, Kelly Pugh, Shannon S Stockton, Jessica Ulloa, Yaomin Xu, Muhamed Baljevic, Sanjay Mohan, Javid J. Moslehi, Eiman Jahangir, Brent Ferrell, Jr., David Slosky, Alexander G. Bick, Michael R. Savona
Journal: Blood
Blood (2023) 142 (Supplement 1): 5594.
https://doi.org/10.1182/blood-2023-189808
Published: 2023
Journal Articles

Transcranial Doppler Screening of Children with Sickle Cell Disease for a Large, Multinational Interventional Study: Experience from the Phase 3 HOPE-Kids 2 Trial Investigating the Effect of Voxelotor Treatment on Transcranial Doppler Flow Velocity

Halima Bello-Manga, Videlis Nduba, Shehu Umar Abdullahi, Jessie Githanga, Bernhards Ogutu, Amal M. El-Beshlawy, Hoda MA Hassab, Mohamed Badr, Azza Tantawy, Biobele J Brown, Vivian Paintsil, Adeseye Michael Akinsete, Catherine I. Segbefia, Iheanyi Okpala, Yasser Wali, Mohammed Essa, Jason Farthing, Jennifer Doss, Sandy Dixon, Clark Brown, Fenella Kirkham
Journal: Blood
Blood (2023) 142 (Supplement 1): 3871.
https://doi.org/10.1182/blood-2023-188677
Published: 2023
Journal Articles

DNMT3A R882H Exhibits Greater Inflammatory Potential Than R882C in Primary Hematopoietic Stem and Progenitor Cell Knock-in Model and Population Data

Alexander J Silver, Donovan J Brown, Caitlyn Vlasschaert, Pawan Bhat, Fabio Puddu, Joseph C Van Amburg, Matthew T Villaume, Melissa A Fischer, Maria P Arrate, Yu Wang, Jamie Scotcher, Kristy Stengel, Brianna Nicole Smith, Brian Sharber, Chad R Potts, Mark Consugar, Jonathan Brett Heimlich, Yaomin Xu, P. Brent Ferrell, Jr., Alexander G. Bick, Michael R. Savona
Journal: Blood
Blood (2023) 142 (Supplement 1): 815.
https://doi.org/10.1182/blood-2023-187244
Published: 2023
Journal Articles

Nonsteroidal anti-inflammatory drugs as a targeted therapy for bone marrow failure in Ghosal hematodiaphyseal dysplasia

Clinical Trials & Observations Brief Report
Timothy J. Brown, Neil Barrett, Hu Meng, Emanuela Ricciotti, Ciara McDonnell, Andrew Dancis, Julianne Qualtieri, Garret A. FitzGerald, Melanie Cotter, Daria V. Babushok
Journal: Blood
Blood (2023) 141 (13): 1553–1559.
https://doi.org/10.1182/blood.2022018667
Published: 2023
Includes: Supplemental data
Journal Articles

Combined Single-Cell Transcriptomics and Mitochondrial Lineage Tracing Identify IL-6 Signaling Responses in TET2 Clonal Hematopoiesis of Indeterminate Potential

Pawan Bhat, J. Brett Heimlich, Alyssa Parker, Matthew T. Jenkins, Chad R. Potts, Jessica Ulloa, Alexander J. Silver, Donovan J. Brown, Peter Van Galen, Michael R. Savona, Alexander G. Bick, Brent Ferrell
Journal: Blood
Blood (2022) 140 (Supplement 1): 2891–2892.
https://doi.org/10.1182/blood-2022-167850
Published: 2022
Journal Articles

Primary HSPC-Derived Monocytes with DNMT3A p.R882H Exhibit Activated Myeloid Cell Gene Signatures

Alexander J. Silver, Donovan J. Brown, Maria P. Arrate, Yu Wang, Melissa A. Fischer, Pawan Bhat, J. Brett Heimlich, Alexander G. Bick, P. Brent Ferrell, Yaomin Xu, Michael R. Savona
Journal: Blood
Blood (2022) 140 (Supplement 1): 2885–2886.
https://doi.org/10.1182/blood-2022-170803
Published: 2022
Journal Articles

Lactate Utilization Provides a Metabolic Escape to Resist the Antileukemic Activity of BET Inhibition in Acute Myeloid Leukemia

Andrew J. Monteith, Haley E. Ramsey, Dalton Greenwood, Maria P. Arrate, Londa Fuller, Agnieszka E. Gorska, Alexander J. Silver, Donovan J. Brown, Sarah D. Olmstead, Jackson Watke, Matthew J. Stubbs, Jeffrey C. Rathmell, Michael R. Savona
Journal: Blood
Blood (2022) 140 (Supplement 1): 8709–8710.
https://doi.org/10.1182/blood-2022-164701
Published: 2022
Journal Articles

Long-term results of PET-guided radiation in patients with advanced-stage diffuse large B-cell lymphoma treated with R-CHOP

Clinical Trials & Observations
Ciara L. Freeman, Kerry J. Savage, Diego R. Villa, David W. Scott, Line Srour, Alina S. Gerrie, Maura J. Brown, Graham W. Slack, Pedro Farinha, Brian Skinnider, James Morris, François Bénard, Christina Aquino-Parsons, Andrea Lo, Tom Pickles, Don C. Wilson, Petter Tonseth, Joseph M. Connors, Laurie H. Sehn
Journal: Blood
Blood (2021) 137 (7): 929–938.
https://doi.org/10.1182/blood.2020005846
Published: 2021
Includes: Supplemental data
Journal Articles

An epitope-based approach of HLA-matched platelets for transfusion: a noninferiority crossover randomized trial

CME Clinical Trials & Observations
Judith C. Marsh, Simon J. Stanworth, Laura A. Pankhurst, Delordson Kallon, Adeline Z. Gilbertson, Collette Pigden, Alison J. Deary, Ana S. Mora, Joanne Brown, Emma S. Laing, Louise L. Choo, Renate Hodge, Charlotte A. Llewelyn, Kay Harding, Deborah Sage, Aleksandar Mijovic, Ghulam J. Mufti, Cristina V. Navarrete, Colin J. Brown
Journal: Blood
Blood (2021) 137 (3): 310–322.
https://doi.org/10.1182/blood.2020007199
Published: 2021
Includes: Supplemental data
Journal Articles

Overall Survival of HIV-Positive Patients with HLH

Timothy J Brown, MD, Bonnie C Prokesch, MD, Srikanth Nagalla, MBBS, MS, Christian Wysocki, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4957.
https://doi.org/10.1182/blood-2018-99-116479
Published: 2018
Journal Articles

Long-Term Results of PET-Guided Radiation Therapy in Patients with Advanced-Stage Diffuse Large B-Cell Lymphoma Treated with R-CHOP in British Columbia

Ciara Louise Freeman, MRCP, MD, Kerry J Savage, BSc, MD MSc, Diego Villa, MD, David W. Scott, MD PhD FRACP, FRCPA, Line Srour, MD, Alina S Gerrie, MD, Maura J Brown, Graham W Slack, MD, Pedro Farinha, Brian Skinnider, Christina Aquino Parsons, Tom Pickles, MD FRCPC, Pete Tonseth, Don Wilson, Joseph M Connors, MD, Laurie H. Sehn, MDMPH
Journal: Blood
Blood (2017) 130 (Supplement 1): 823.
https://doi.org/10.1182/blood.V130.Suppl_1.823.823
Published: 2017
Journal Articles

Ex vivo drug response profiling detects recurrent sensitivity patterns in drug-resistant acute lymphoblastic leukemia

e-blood
Viktoras Frismantas, Maria Pamela Dobay, Anna Rinaldi, Joelle Tchinda, Samuel H. Dunn, Joachim Kunz, Paulina Richter-Pechanska, Blerim Marovca, Orrin Pail, Silvia Jenni, Ernesto Diaz-Flores, Bill H. Chang, Timothy J. Brown, Robert H. Collins, Sebastian Uhrig, Gnana P. Balasubramanian, Obul R. Bandapalli, Salome Higi, Sabrina Eugster, Pamela Voegeli, Mauro Delorenzi, Gunnar Cario, Mignon L. Loh, Martin Schrappe, Martin Stanulla, Andreas E. Kulozik, Martina U. Muckenthaler, Vaskar Saha, Julie A. Irving, Roland Meisel, Thomas Radimerski, Arend Von Stackelberg, Cornelia Eckert, Jeffrey W. Tyner, Peter Horvath, Beat C. Bornhauser, Jean-Pierre Bourquin
Journal: Blood
Blood (2017) 129 (11): e26–e37.
https://doi.org/10.1182/blood-2016-09-738070
Published: 2017
Includes: Supplemental data
Journal Articles

Ischemic Stroke in Children and Young Adults with Sickle Cell Disease (SCD) in the Post-STOP Era

Janet L. Kwiatkowski, MD MSCE, Julie Kanter, MD, Heather J. Fullerton, MD, Jenifer Voeks, Ellen Debenham, RN, David G Brown, Lynette J Brown, Robert J. Adams, MD MS
Journal: Blood
Blood (2015) 126 (23): 68.
https://doi.org/10.1182/blood.V126.23.68.68
Published: 2015
Journal Articles

Impact of TCD Screening Protocol on the Incidence of Hemorrhagic Stroke in Children and Young Adults with Sickle Cell Disease

Julie Kanter, MD, Janet Kwiatkowski, MD, Heather J. Fullerton, MD, Jenifer Voeks, Ellen Debenham, RN, Lynette J Brown, Robert J. Adams, MD MS
Journal: Blood
Blood (2015) 126 (23): 3402.
https://doi.org/10.1182/blood.V126.23.3402.3402
Published: 2015
Journal Articles

Circulatory hepcidin is associated with the anti-inflammatory response but not with iron or anemic status in childhood malaria

Florence Burté, Biobele J. Brown, Adebola E. Orimadegun, Wasiu A. Ajetunmobi, Nathaniel K. Afolabi, Francis Akinkunmi, Olayinka Kowobari, Samuel Omokhodion, Kikelomo Osinusi, Felix O. Akinbami, Wuraola A. Shokunbi, Olugbemiro Sodeinde, Delmiro Fernandez-Reyes
Journal: Blood
Blood (2013) 121 (15): 3016–3022.
https://doi.org/10.1182/blood-2012-10-461418
Published: 2013
Includes: Supplemental data
Journal Articles

Identification of FOXP1 Transcriptional Targets in Diffuse Large B Cell Lymphoma

Emily T Camilleri, Hons, PhD Student, Carlos A Aya-Bonilla, MSc, PhD student, Philip J Brown, PhD, Alison Banham, DPhil, Paula Marlton, MBBS, FRACP, FRCPA, Maher K Gandhi, PhD, FRACP, FRCPath, FRCP, Lyn R Griffiths, Hons, PhD
Journal: Blood
Blood (2012) 120 (21): 5119.
https://doi.org/10.1182/blood.V120.21.5119.5119
Published: 2012
Journal Articles

Enhancing Ceramide Cytotoxicity in Acute Myelogenous Leukemia

Timothy J Brown, B.S., Brian Barth, Ph.D., David F. Claxton, MD
Journal: Blood
Blood (2012) 120 (21): 4905.
https://doi.org/10.1182/blood.V120.21.4905.4905
Published: 2012
Journal Articles

Perspectives Among Primary Care Providers and Hematologist/Oncologists in the Coordination of Care for Patients with Hematologic Malignancies

Haleh Kadkhoda, Clare Karten, MS, Kevin C. Oeffinger, MD, Kanti R. Rai, M.D., S. Frieda Pearce, PhD, Margaret Miller, Jennifer J. Brown, PhD, Nancy Roepke, MS, Ryan Palmore, MA, MS, Jennifer Garick
Journal: Blood
Blood (2011) 118 (21): 3156.
https://doi.org/10.1182/blood.V118.21.3156.3156
Published: 2011
Journal Articles

Impaired FcϵRI stability, signaling, and effector functions in murine mast cells lacking glycosylphosphatidylinositol-anchored proteins

Wouter L. W. Hazenbos, Ping Wu, Jeffrey Eastham-Anderson, Taroh Kinoshita, Eric J. Brown
Journal: Blood
Blood (2011) 118 (16): 4377–4383.
https://doi.org/10.1182/blood-2011-02-338053
Published: 2011
Journal Articles

Low-dose radiation augments vasculogenesis signaling through HIF-1–dependent and –independent SDF-1 induction

Oren Z. Lerman, Matthew R. Greives, Sunil P. Singh, Vishal D. Thanik, Christopher C. Chang, Natalie Seiser, Daniel J. Brown, Denis Knobel, Robert J. Schneider, Silvia C. Formenti, Pierre B. Saadeh, Jamie P. Levine
Journal: Blood
Blood (2010) 116 (18): 3669–3676.
https://doi.org/10.1182/blood-2009-03-213629
Published: 2010