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Bruno C Medeiros
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Journal Articles

Activity of eftozanermin alfa plus venetoclax in preclinical models and patients with acute myeloid leukemia

Clinical Trials & Observations
Stephen K. Tahir, Emiliano Calvo, Benedito A. Carneiro, Junichiro Yuda, Aditya Shreenivas, Mojca Jongen-Lavrencic, Eelke Gort, Kenichi Ishizawa, Daniel Morillo, Carla Biesdorf, Morey Smith, Dong Cheng, Monica Motwani, David Sharon, Tamar Uziel, Dimple A. Modi, Fritz G. Buchanan, Susan Morgan-Lappe, Bruno C. Medeiros, Darren C. Phillips
Journal: Blood
Blood (2023) 141 (17): 2114–2126.
https://doi.org/10.1182/blood.2022017333
Published: 2023
Includes: Supplemental data
Journal Articles

An 8-year pragmatic observation evaluation of the benefits of allogeneic HCT in older and medically infirm patients with AML

Clinical Trials & Observations
Mohamed L. Sorror, Ted A. Gooley, Barry E. Storer, Aaron T. Gerds, Mikkael A. Sekeres, Bruno C. Medeiros, Eunice S. Wang, Paul J. Shami, Kehinde Adekola, Selina Luger, Maria R. Baer, David A. Rizzieri, Tanya M. Wildes, Jamie Koprivnikar, Julie Smith, Mitchell Garrison, Kiarash Kojouri, Tammy A. Schuler, Wendy M. Leisenring, Lynn E. Onstad, Pamela S. Becker, Jeannine S. McCune, Stephanie J. Lee, Brenda M. Sandmaier, Frederick R. Appelbaum, Elihu H. Estey
Journal: Blood
Blood (2023) 141 (3): 295–308.
https://doi.org/10.1182/blood.2022016916
Published: 2023
Includes: Supplemental data
Journal Articles

CD25 Targeting Eliminates Regulatory T Cells and CD25+ Blasts in Acute Myeloid Leukemia

Laurene Pousse, Bruno C. Medeiros, Koorosh Korfi, Marco Berrera, Nadine Kumpesa, Vera Griesser, Jan Eckmann, Vaios Karanikas, Christian Klein, Maria Amann
Journal: Blood
Blood (2022) 140 (Supplement 1): 6291–6292.
https://doi.org/10.1182/blood-2022-158189
Published: 2022
Journal Articles

Novel Data Analytics Identify Predictors of Quality-of-Life Trajectories in Patients with AML or High-Risk Myeloid Neoplasms

Jordan Gauthier, Bianca Furtuna, Jacopo Mangiavacchi, Shahrzad Gholami, Juan Lavista Ferres, Rahul Dodhia, Amir T. Fathi, Andrew M. Brunner, Aaron T. Gerds, Mikkael A. Sekeres, Bruno C. Medeiros, Eunice S. Wang, Paul J Shami, Kehinde Adekola, Selina M. Luger, Maria R. Baer, David A Rizzieri, Tanya Wildes, Jamie L. Koprivnikar, Julie Smith, Mitchell A. Garrison, Kiarash Kojouri, Frederick R. Appelbaum, Mary-Elizabeth M. Percival, Stephanie J. Lee, Mohamed L. Sorror
Journal: Blood
Blood (2022) 140 (Supplement 1): 5254–5257.
https://doi.org/10.1182/blood-2022-165437
Published: 2022
Journal Articles

Multisite 11-year experience of less-intensive vs intensive therapies in acute myeloid leukemia

Clinical Trials & Observations
Mohamed L. Sorror, Barry E. Storer, Amir T. Fathi, Andrew Brunner, Aaron T. Gerds, Mikkael A. Sekeres, Sudipto Mukherjee, Bruno C. Medeiros, Eunice S. Wang, Pankit Vachhani, Paul J. Shami, Esteban Peña, Mahmoud Elsawy, Kehinde Adekola, Selina Luger, Maria R. Baer, David Rizzieri, Tanya M. Wildes, Jamie Koprivnikar, Julie Smith, Mitchell Garrison, Kiarash Kojouri, Wendy Leisenring, Lynn Onstad, Jennifer E. Nyland, Pamela S. Becker, Jeannine S. McCune, Stephanie J. Lee, Brenda M. Sandmaier, Frederick R. Appelbaum, Elihu H. Estey
Journal: Blood
Blood (2021) 138 (5): 387–400.
https://doi.org/10.1182/blood.2020008812
Published: 2021
Includes: Supplemental data
Journal Articles

Impact of NPM1 / FLT3 -ITD genotypes defined by the 2017 European LeukemiaNet in patients with acute myeloid leukemia

Clinical Trials & Observations
Konstanze Döhner, Christian Thiede, Nikolaus Jahn, Ekaterina Panina, Agnes Gambietz, Richard A. Larson, Thomas W. Prior, Guido Marcucci, Dan Jones, Jürgen Krauter, Michael Heuser, Maria Teresa Voso, Tiziana Ottone, Josep F. Nomdedeu, Sumithra J. Mandrekar, Rebecca B. Klisovic, Andrew H. Wei, Jorge Sierra, Miguel A. Sanz, Joseph M. Brandwein, Theo de Witte, Joop H. Jansen, Dietger Niederwieser, Frederick R. Appelbaum, Bruno C. Medeiros, Martin S. Tallman, Richard F. Schlenk, Arnold Ganser, Hubert Serve, Gerhard Ehninger, Sergio Amadori, Insa Gathmann, Axel Benner, Celine Pallaud, Richard M. Stone, Hartmut Döhner, Clara D. Bloomfield
Journal: Blood
Blood (2020) 135 (5): 371–380.
https://doi.org/10.1182/blood.2019002697
Published: 2020
Includes: Supplemental data
Journal Articles

Genomic landscape of neutrophilic leukemias of ambiguous diagnosis

Haijiao Zhang, Beth Wilmot, Daniel Bottomly, Kim-Hien T. Dao, Emily Stevens, Christopher A. Eide, Vishesh Khanna, Angela Rofelty, Samantha Savage, Anna Reister Schultz, Nicola Long, Libbey White, Amy Carlos, Rachel Henson, Chenwei Lin, Robert Searles, Robert H. Collins, Daniel J. DeAngelo, Michael W. Deininger, Tamara Dunn, Than Hein, Marlise R. Luskin, Bruno C. Medeiros, Stephen T. Oh, Daniel A. Pollyea, David P. Steensma, Richard M. Stone, Brian J. Druker, Shannon K. McWeeney, Julia E. Maxson, Jason R. Gotlib, Jeffrey W. Tyner
Journal: Blood
Blood (2019) 134 (11): 867–879.
https://doi.org/10.1182/blood.2019000611
Published: 2019
Includes: Supplemental data
Journal Articles

Prognostic Impact of Insertion Site in Acute Myeloid Leukemia (AML) with FLT3 Internal Tandem Duplication: Results from the Ratify Study (Alliance 10603)

Frank G. Rücker, MD, Ling Du, PhD, Tamara J. Blätte, MSc, Axel Benner, Julia Krzykalla, MSc, Insa Gathmann, Richard A. Larson, MD, Francesco Lo-Coco, MD, Sergio Amadori, MD, Thomas W Prior, MD, Joseph M. Brandwein, MD, Frederick R. Appelbaum, MD, Bruno C. Medeiros, MD, Martin S. Tallman, MD, Michelle Geddes, MD, Jorge Sierra, MD, Eva Tiecke, PhD, Celine Pallaud, PhD, Miguel A. Sanz, MD, Theo M de Witte, MD, Dietger Niederwieser, MD, Gerhard Ehninger, MD, Michael Heuser, MD, Arnold Ganser, MD, Lars Bullinger, MD, Clara D. Bloomfield, MD, Richard M. Stone, MD, Hartmut Döhner, MD, Christian Thiede, MD, Konstanze Dohner, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 435.
https://doi.org/10.1182/blood-2018-99-116149
Published: 2018
Journal Articles

Single-Cell Mutational Profiling of Clonal Evolution in De Novo AML during Therapy and Relapse

Alexey Aleshin, MD MBA, Robert Durruthy-Durruthy, PhD, M. Ryan Corces, PhD, Melissa Stafford, Michaela Liedtke, MD, Bruno C. Medeiros, MD, Dennis J. Eastburn, PhD, Ravindra Majeti, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1469.
https://doi.org/10.1182/blood-2018-99-118089
Published: 2018
Journal Articles

Comprehensive Molecular Profiling of FLT3 -Mutated Acute Myeloid Leukemia (AML) Patients Treated within the Ratify Trial (Alliance C10603)

Nikolaus Jahn, MD, Ekaterina Panina, MD, Lars Bullinger, MD, Anna Dolnik, PhD, Julia Herzig, PhD, Tamara J. Blätte, MSc, Axel Benner, Julia Krzykalla, MSc, Insa Gathmann, Richard A. Larson, MD, Francesco Lo-Coco, MD, Sergio Amadori, MD, Thomas W Prior, MD, Joseph M. Brandwein, MD, Frederick R. Appelbaum, MD, Bruno C. Medeiros, MD, Martin S. Tallman, MD, Eva Tiecke, PhD, Celine Pallaud, PhD, Gerhard Ehninger, MD, Michael Heuser, MD, Arnold Ganser, MD, Richard M. Stone, MD, Christian Thiede, MD, Hartmut Döhner, MD, Clara D. Bloomfield, MD, Konstanze Döhner, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1534.
https://doi.org/10.1182/blood-2018-99-115842
Published: 2018
Journal Articles

Longer Distance to a Specialized Treatment Center Does Not Adversely Affect Access to Treatment or Outcome in Acute Myeloid Leukemia: A National Population-Based Cohort Study

Michael Buch Tostesen, MD, Jan M. Norgaard, MD PhD, Mette Nørgaard, MD PhD, Bruno C. Medeiros, MD, Claus Werenberg Marcher, MD PhD, Ulrik Malthe Overgaard, MD, Claudia Schöllkopf, MD PhD, Marianne Tang Severinsen, MD PhD, Lene Sofie Granfeldt Oestgaard, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 613.
https://doi.org/10.1182/blood-2018-99-110922
Published: 2018
Journal Articles

Real-World Treatment Patterns and Comparative Effectiveness Among a Population of Elderly Patients with Acute Myeloid Leukemia (AML)

Bruno C. Medeiros, MD, Sacha Satram-Hoang, Faiyaz Momin, Monika Parisi
Journal: Blood
Blood (2018) 132 (Supplement 1): 835.
https://doi.org/10.1182/blood-2018-99-111267
Published: 2018
Journal Articles

Dynamic BH3 Profiling Predicts for Clinical Response to Lenalidomide Plus Chemotherapy in Relapsed Acute Myeloid Leukemia

Jacqueline S Garcia, MD, Shruti Bhatt, PhD, Geoffrey Fell, PhD, Traci M. Blonquist, MS, Jack Taw, David Iberri, MD, Anthony Letai, MD PhD, Bruno C. Medeiros, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4058.
https://doi.org/10.1182/blood-2018-99-117428
Published: 2018
Journal Articles

Augmentation of the Acute Myeloid Leukemia-Composite Model (AML-CM) with Performance Status and Secondary Leukemia

Sarah Elsayed, MD, Barry E. Storer, PhD, Bruno C. Medeiros, MD, Mona Ahmed Asslan, MSc, Ylinne Lynch, MD, Jennifer E. Nyland, PhD, Pamela S. Becker, MD, Mary-Elizabeth M. Percival, MD, Elihu H. Estey, MD, Mohamed L. Sorror, MD MSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 3992.
https://doi.org/10.1182/blood-2018-99-117415
Published: 2018
Journal Articles

The Relationship between Age and Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in a Cohort of Older Patients with Acute Myeloid Leukemia (AML)

Bruno C. Medeiros, MD, Sacha Satram-Hoang, Faiyaz Momin, Monika Parisi
Journal: Blood
Blood (2018) 132 (Supplement 1): 3588.
https://doi.org/10.1182/blood-2018-99-111274
Published: 2018
Journal Articles

Increase in Chemotherapy Use and Associated Survival Benefit Among Medicare-Aged Patients with Acute Myeloid Leukemia (AML)

Bruno C. Medeiros, MD, Sacha Satram-Hoang, Faiyaz Momin, Monika Parisi
Journal: Blood
Blood (2018) 132 (Supplement 1): 3591.
https://doi.org/10.1182/blood-2018-99-111281
Published: 2018
Journal Articles

Ratify (Alliance 10603): Prognostic Impact of FLT3 tyrosine Kinase Domain (TKD) and NPM1 Mutation Status in Patients with Newly Diagnosed Acute Myeloid Leukemia (AML) Treated with Midostaurin or Placebo Plus Standard Chemotherapy

Maria Teresa Voso, Richard A. Larson, MD, Thomas Prior, Guido Marcucci, Dan Jones, MD PhD, Jürgen Krauter, MD, Michael Heuser, MD, Serena Lavorgna, PhD, Josep Nomdedeu, MD PhD, Susan M. Geyer, PhD, Rebecca Klisovic, MD, Andrew H Wei, MBBS, PhD, Jorge Sierra, MD, Miguel A. Sanz, MD, Joseph M. Brandwein, MD FRCPC, Theo M de Witte, MD, Joop H. Jansen, Dietger Niederweiser, Frederick R. Appelbaum, MD, Bruno C. Medeiros, MD, Martin S. Tallman, MD, Richard F. Schlenk, MD, Arnold Ganser, MD, Sergio Amadori, MD, Yuan Cheng, PhD, Insa Gathmann, Eva Tiecke, PhD, Christian Thiede, MD, Konstanze Döhner, MD, Hartmut Döhner, MD, Richard M. Stone, MD, Clara D. Bloomfield, MD, Francesco Lo-Coco, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2668.
https://doi.org/10.1182/blood-2018-99-114318
Published: 2018
Journal Articles

Limitations to Receiving Allogeneic Hematopoietic Cell Transplantation for Treatment of Acute Myeloid Leukemia: A Large Multi-Center Prospective Longitudinal Observational Study

Mohamed L. Sorror, MD MSc, Barry E. Storer, PhD, Aaron T. Gerds, MDMS, Bruno C. Medeiros, MD, Paul J Shami, MD, John P. Galvin, MDMS,MPH, Kehinde U. Adekola, MBBS,MS, Selina Luger, MD, Maria R. Baer, MD, David A. Rizzieri, MD, Tanya M. Wildes, MD MSCI, Eunice S. Wang, MD, Stefan Faderl, MD, Jamie L. Koprivnikar, MD, Mikkael A. Sekeres, MD MS, Sudipto Mukherjee, MDPhDMPH, Julie Smith, MD, Mitchell Garrison, MD, Kiarash Kojouri, MD, Jennifer E. Nyland, PhD, Rachelle R. Moore, BS, Sophie L. Fleuret, BS, Ylinne Lynch, MD, Pamela S. Becker, MD, Mary-Elizabeth M. Percival, MD, Brenda M. Sandmaier, MD, Frederick R. Appelbaum, MD, Elihu H. Estey, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1388.
https://doi.org/10.1182/blood-2018-99-112672
Published: 2018
Journal Articles

Single-Cell Mutational Profiling Describes the Molecular Heterogeneity of Clonal Evolution in MDS during Therapy and Relapse

Alexey Aleshin, MD MBA, Robert Durruthy-Durruthy, PhD, Bruno C. Medeiros, MD, Dennis J. Eastburn, PhD, Peter L Greenberg, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5503.
https://doi.org/10.1182/blood-2018-99-120368
Published: 2018
Journal Articles

PD-L1 Blockade with Atezolizumab in Higher-Risk Myelodysplastic Syndrome: An Initial Safety and Efficacy Analysis

Aaron T. Gerds, MDMS, Bart L Scott, MD, Peter L Greenberg, MD, Samer K. Khaled, MD, Tara L Lin, MD, Daniel A Pollyea, MD, Amit Verma, MD, Monique Dail, Cherie Green, Connie Ma, Bruno C Medeiros, Patrick Phuong, Michael Wenger, Mark Yan, William B. Donnellan, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 466.
https://doi.org/10.1182/blood-2018-99-118577
Published: 2018