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Journal Articles

CSF2RB Mutations Result in Cytokine-Dependent Gain-of-Function Phenotypes in Classic Hodgkin Lymphoma

Shinya Rai, Tomohiro Aoki, Gerben Duns, Aixiang Jiang, Andrew Lytle, Yifan Yin, Makoto Kishida, Michael Yu Li, Denise Smorra, Cecilia Lee, Katy Milne, Adele Telenius, Luke O'Brien, Katsuyoshi Takata, Tomoko Miyata-Takata, Merrill Boyle, Susana Ben-Neriah, Andrew P. Weng, Andrew Roth, Brad H NelsonH, Laura K. Hilton, Pedro Farinha, Kerry J. Savage, David W. Scott, Christian Steidl
Journal: Blood
Blood (2024) 144 (Supplement 1): 855.
https://doi.org/10.1182/blood-2024-199981
Published: 2024
Journal Articles

Multiomic Profiling Reveals Pleiotropic Effects of Somatic IRF4-C99R Mutations in Primary Mediastinal Large B-Cell Lymphomas

Shinya Rai, Gerben Duns, Fabian Frontzek, Jasper Wong, Yifan Yin, Shannon Healy, Michael Yu Li, Makoto Kishida, Elena Viganò, Manabu Fujisawa, Bruce Woolcock, Adele Telenius, Barbara Meissner, Merrill Boyle, Hisae Nakamura, Luke O'Brien, Andrew Lytle, Pedro Farinha, Graham W. Slack, Laura K. Hilton, Ryan Morin, Leandro Venturutti, Tomohiro Aoki, Kerry J. Savage, David W. Scott, Christian Steidl
Journal: Blood
Blood (2024) 144 (Supplement 1): 2966.
https://doi.org/10.1182/blood-2024-199227
Published: 2024
Journal Articles

Genomic, Transcriptional, and Immunological Validation of Distinct Molecular Subtypes of Classic Hodgkin Lymphoma through Tissue-Based and Noninvasive Methods

Stefan K. Alig, Mohammad Shahrokh Esfahani, Andrea Garofalo, Michael Yu Li, Cédric Rossi, Timothy Flerlage, Jamie E. Flerlage, Ragini Adams, Michael S. Binkley, Navika Shukla, Michael Jin, Mari Olsen, Adele Telenius, Jurik A Mutter, Joseph Schroers-Martin, Brian J. Sworder, Shinya Rai, Daniel King, Andre Schultz, Jan Lukas Bögeholz, Shengqin Su, Karan R Kathuria, Chih Long Liu, Xiaoman Kang, Deanna M. Langfitt, Kristine Faye Pobre-Piza, Feng Tian, Maya J. Strohband, Valeria Spina, Thomas Tousseyn, Lieselot Buedts, Luc-Matthieu Fornecker, Sharon M. Castellino, Ranjana H. Advani, Davide Rossi, Ryan C Lynch, Herve Ghesquieres, Olivier Casasnovas, David M. Kurtz, Lianna J. Marks, Michael P. Link, Marc Andre, Peter Vandenberghe, Christian Steidl, Maximilian Diehn, Ash A. Alizadeh
Journal: Blood
Blood (2023) 142 (Supplement 1): 177.
https://doi.org/10.1182/blood-2023-186810
Published: 2023
Journal Articles

Multi-Dimensional Molecular and Tumor-Microenvironment Analysis of Classic Hodgkin Lymphoma

Tomohiro Aoki, Gerben Duns, Shinya Rai, Andrew Lytle, Yifan Yin, Clementine Sarkozy, Stacy Hung, Katy Milne, Adele Telenius, Luke O'Brien, Celia Strong, Talia Goodyear, Shaocheng Wu, Katsuyoshi Takata, Tomoko Miyata-Takata, Merrill Boyle, Susana Ben-Neriah, Andrew P. Weng, Andrew Roth, Anca Prica, Robert Kridel, Brad Nelson, Pedro Farinha, Kerry J. Savage, David W. Scott, Christian Steidl
Journal: Blood
Blood (2023) 142 (Supplement 1): 172.
https://doi.org/10.1182/blood-2023-174139
Published: 2023
Journal Articles

TRAF3 Loss-of-Function Reveals the Non-Canonical NF-Κb Pathway As a Therapeutic Target in Diffuse Large B-Cell Lymphoma

Michael Y. Li, Lauren C. Chong, Bruce W Woolcock, Adèle Telenius, Susana Ben-Neriah, Graham W Slack, Vivian Lam, Aixiang Jiang, Elena Viganò, Tomohiro Aoki, Shannon Healy, Gerald Krystal, Leandro Venturutti, David W. Scott, Christian Steidl
Journal: Blood
Blood (2022) 140 (Supplement 1): 2042–2043.
https://doi.org/10.1182/blood-2022-159679
Published: 2022
Journal Articles

Spatial Tumor Microenvironment Characterization and Outcome of Relapsed/Refractory Classic Hodgkin Lymphoma

Tomohiro Aoki, Aixiang Jiang, Alexander Xu, Alicia Gamboa, Yifan Yin, Katy Milne, Celia Strong, Talia Goodyear, Shaocheng Wu, Lauren C. Chong, Katsuyoshi Takata, Elizabeth Chavez, Tomoko Miyata-Takata, Anthony R. Colombo, Monirath Hav, Adele Telenius, Susana Ben-Neriah, Andrew P. Weng, Kerry J. Savage, David W. Scott, Andrew Roth, Pedro Farinha, Brad H Nelson, Akil Merchant, Christian Steidl
Journal: Blood
Blood (2022) 140 (Supplement 1): 170–171.
https://doi.org/10.1182/blood-2022-158709
Published: 2022
Journal Articles

Distinct Molecular Subtypes of Classic Hodgkin Lymphoma Identified By Comprehensive Noninvasive Profiling

Stefan K. Alig, Mohammad Shahrokh Esfahani, Michael Y. Li, Ragini Malika Adams, Andrea Garofalo, Michael C. Jin, Mari Olsen, Adèle Telenius, Brian Sworder, Joseph Schroers-Martin, Daniel A. King, Cédric Rossi, Andre Schultz, Karan R. Kathuria, Chih Long Liu, Valeria Spina, Lieselot Buedts, Jamie E. Flerlage, Sharon M. Castellino, Ranjana H. Advani, Davide Rossi, Ryan C. Lynch, Olivier Casasnovas, David M. Kurtz, Lianna J. Marks, Michael P. Link, Marc André, Peter Vandenberghe, Christian Steidl, Maximilian Diehn, Ash A. Alizadeh
Journal: Blood
Blood (2022) 140 (Supplement 1): 1295–1296.
https://doi.org/10.1182/blood-2022-164744
Published: 2022
Journal Articles

A gene expression–based model predicts outcome in children with intermediate-risk classical Hodgkin lymphoma

Clinical Trials & Observations Brief Report
Rebecca L. Johnston, Anja Mottok, Fong Chun Chan, Aixiang Jiang, Arjan Diepstra, Lydia Visser, Adèle Telenius, Randy D. Gascoyne, Debra L. Friedman, Cindy L. Schwartz, Kara M. Kelly, David W. Scott, Terzah M. Horton, Christian Steidl
Journal: Blood
Blood (2022) 139 (6): 889–893.
https://doi.org/10.1182/blood.2021011941
Published: 2022
Includes: Supplemental data
Journal Articles

Mutational landscape of gray zone lymphoma

Clémentine Sarkozy, Stacy S. Hung, Elizabeth A. Chavez, Gerben Duns, Katsuyoshi Takata, Lauren C. Chong, Tomohiro Aoki, Aixiang Jiang, Tomoko Miyata-Takata, Adèle Telenius, Graham W. Slack, Thierry Jo Molina, Susana Ben-Neriah, Pedro Farinha, Peggy Dartigues, Diane Damotte, Anja Mottok, Gilles A. Salles, Rene-Olivier Casasnovas, Kerry J. Savage, Camille Laurent, David W. Scott, Alexandra Traverse-Glehen, Christian Steidl
Journal: Blood
Blood (2021) 137 (13): 1765–1776.
https://doi.org/10.1182/blood.2020007507
Published: 2021
Includes: Supplemental data
Journal Articles

Nfkbiz 3′ UTR Mutations Confer Selective Growth Advantage and Affect Drug Response in Diffuse Large B-Cell Lymphoma

Sarah E Arthur, BSc, Nicole Thomas, BSc, Christopher Rushton, BSc, Jeffrey Tang, Miguel Alcaide, PhD, Shannon Healy, PhD, Adele Telenius, Anja Mottok, MD PhD, David W. Scott, MBChB, PhD, Christian Steidl, MD, Ryan D Morin, PhDBSc,MSc
Journal: Blood
Blood (2020) 136 (Supplement 1): 31.
https://doi.org/10.1182/blood-2020-137700
Published: 2020
Journal Articles

Single Cell Profiling Reveals Unique CXCL13 Positive T Cell Subsets in the Tumor Microenvironment of Lymphocyte Rich Classic Hodgkin Lymphoma

Tomohiro Aoki, MD PhD, Lauren C. Chong, MSc, Katsuyoshi Takata, MD PhD, Katy Milne, Elizabeth Chavez, BSc, Cg RT, Tomoko Miyata-Takata, MD PhD, Susana Ben-Neriah, BSc, Doria Unrau, Adele Telenius, Merrill Boyle, BSc, Pedro Farinha, MD PhD, Andrew P. Weng, MD, Kerry J. Savage, MDMSc, David W. Scott, MBChB, PhD, Sohrab P Shah, Brad H. Nelson, Christian Steidl, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 32–33.
https://doi.org/10.1182/blood-2020-134929
Published: 2020
Journal Articles

The Tumor Associated Antigen PRAME Exhibits Dualistic Functions That Are Targetable in Diffuse Large B-Cell Lymphoma

Katsuyoshi Takata, MD PhD, Lauren C. Chong, MSc, Daisuke Ennishi, MD PhD, Avinash Thakur, PhD, Shannon Healy, PhD, Elena Viganò, PhD, Tao Dao, MD PhD, Julie S Nielsen, Susana Ben-Neriah, BSc, Tomohiro Aoki, MD PhD, Ethan Tse, Stacy Hung, Michael Y. Li, BS, Merrill Boyle, BSc, Sung Soo Mun, Christopher Bourne, Bruce W Woolcock, Adele Telenius, Allen Zhang, Ali Bashashati, Saeed Saberi, Gianluca D' Antonio, Brad H Nelson, Sohrab P Shah, Pamela Hoodless, Ari Melnick, MD, Randy D. Gascoyne, MD, Joseph M Connors, MD, David A. Scheinberg, MD PhD, Wendy Béguelin, PhD, David W. Scott, MBChB, PhD, Christian Steidl, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34.
https://doi.org/10.1182/blood-2020-141168
Published: 2020
Journal Articles

TRAF3 Loss Drives Alternative NF-κB Pathway Activation in Diffuse Large B-Cell Lymphoma

Michael Y. Li, BS, Lauren C. Chong, MSc, Elizabeth Chavez, BSc, Cg RT, Bruce W Woolcock, Adele Telenius, Vivian Lam, Gerald Krystal, PhD, David W. Scott, MBChB, PhD, Elena Viganò, PhD, Shannon Healy, PhD, Christian Steidl, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 22–23.
https://doi.org/10.1182/blood-2020-141126
Published: 2020
Journal Articles

Mutational Landscape of Grey Zone Lymphoma

Clementine Sarkozy, MD, Stacy Hung, Katsuyoshi Takata, MD PhD, Elizabeth Chavez, BSc, Cg RT, Tomohiro Aoki, MD PhD, Gerben Duns, PhD, Graham W Slack, MD PhD, Adele Telenius, Tomoko Miyata-Takata, Elena Viganò, PhD, Thierry Jo Molina, MDPhD, Diane Damotte, MDPhD, Susana Ben-Neriah, BSc, Christiane Copie-Bergman, MD PhD, Camille Laurent, MD PhD, Anja Mottok, MD PhD, Gilles Salles, MD PhD, Kerry J Savage, BSc, MD MSc, David W. Scott, MBChB, PhD, Alexandra Traverse-Glehen, MD PhD, Christian Steidl, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 21.
https://doi.org/10.1182/blood-2019-127375
Published: 2019
Journal Articles

Integrative genomic analysis identifies key pathogenic mechanisms in primary mediastinal large B-cell lymphoma

Anja Mottok, Stacy S. Hung, Elizabeth A. Chavez, Bruce Woolcock, Adèle Telenius, Lauren C. Chong, Barbara Meissner, Hisae Nakamura, Christopher Rushton, Elena Viganò, Clementine Sarkozy, Randy D. Gascoyne, Joseph M. Connors, Susana Ben-Neriah, Andrew Mungall, Marco A. Marra, Reiner Siebert, David W. Scott, Kerry J. Savage, Christian Steidl
Journal: Blood
Blood (2019) 134 (10): 802–813.
https://doi.org/10.1182/blood.2019001126
Published: 2019
Includes: Supplemental data
Journal Articles

Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 As a Therapeutic Target for Restoring MHC Expression in Diffuse Large B-Cell Lymphoma

Daisuke Ennishi, MDPhD, Katsuyoshi Takata, MD PhD, Wendy Béguelin, PhD, Gerben Duns, PhD, Anja Mottok, Pedro Farinha, MD PhD, Ali Bashashati, David Scott, Merrill Boyle, BSc, Barbara Meissner, PhD, Susana Ben-Neriah, BSc, Bruce W Woolcock, Adele Telenius, Daniel Lai, Matthew R Teater, PhD, Robert Kridel, PhD MD, Kerry J Savage, BSc, MD MSc, Laurie H Sehn, MD MPH, Ryan D. Morin, PhD BSc MSc, Marco A. Marra, PhD, Sohrab P Shah, Joseph M. Connors, MD, Randy D. Gascoyne, MD, David W. Scott, PhD MD FRACP FRCPA, Ari M Melnick, MD, Christian Steidl, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1560.
https://doi.org/10.1182/blood-2018-99-112010
Published: 2018
Journal Articles

UBR5 Mutations in Mantle Cell Lymphoma Lead to Increased Proliferation through a Cyclin D1-Dependent Mechanism

Olga Kutovaya, PhD, Stacy Hung, Elena Viganò, PhD, Adele Telenius, Bruce W Woolcock, Barbara Meissner, PhD, Shane Colborne, BSc, Randy D. Gascoyne, MD, Diego Villa, MD, Ryan D. Morin, PhD, BSc, MSc, David W. Scott, PhD MD, FRACP, FRCPA, Gregg B Morin, PhD, Christian Steidl, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2849.
https://doi.org/10.1182/blood-2018-99-118524
Published: 2018
Journal Articles

Somatic IL4R mutations in primary mediastinal large B-cell lymphoma lead to constitutive JAK-STAT signaling activation

Elena Viganò, Jay Gunawardana, Anja Mottok, Tessa Van Tol, Katina Mak, Fong Chun Chan, Lauren Chong, Elizabeth Chavez, Bruce Woolcock, Katsuyoshi Takata, David Twa, Hennady P. Shulha, Adèle Telenius, Olga Kutovaya, Stacy S. Hung, Shannon Healy, Susana Ben-Neriah, Karen Leroy, Philippe Gaulard, Arjan Diepstra, Robert Kridel, Kerry J. Savage, Lisa Rimsza, Randy Gascoyne, Christian Steidl
Journal: Blood
Blood (2018) 131 (18): 2036–2046.
https://doi.org/10.1182/blood-2017-09-808907
Published: 2018
Includes: Supplemental data
Journal Articles

Divergent Modes of Tumor Evolution Underlie Histological Transformation and Early Progression of Follicular Lymphoma

Fong Chun Chan, Robert Kridel, Anja Mottok, Merrill Boyle, Pedro Farinha, King Tan, Barbara Meissner, Ali Bashashati, Andrew McPherson, PhD, Andrew Roth, PhD, Karey Shumansky, Damian Yap, PhD, Susana Ben-Neriah, Jamie Rosner, Maia A. Smith, Cydney Nielsen, PhD, Adele Telenius, Daisuke Ennishi, Andrew J. Mungall, Richard Moore, PhD, Ryan D. Morin, Nathalie A. Johnson, Laurie H Sehn, MD, Joseph M. Connors, David W Scott, MBChB, PhD, Christian Steidl, Marco A. Marra, PhD, Randy D Gascoyne, MD, Sohrab P. Shah
Journal: Blood
Blood (2016) 128 (22): 1091.
https://doi.org/10.1182/blood.V128.22.1091.1091
Published: 2016
Journal Articles

Cell of origin of transformed follicular lymphoma

Robert Kridel, Anja Mottok, Pedro Farinha, Susana Ben-Neriah, Daisuke Ennishi, Yvonne Zheng, Elizabeth A. Chavez, Hennady P. Shulha, King Tan, Fong Chun Chan, Merrill Boyle, Barbara Meissner, Adele Telenius, Laurie H. Sehn, Marco A. Marra, Sohrab P. Shah, Christian Steidl, Joseph M. Connors, David W. Scott, Randy D. Gascoyne
Journal: Blood
Blood (2015) 126 (18): 2118–2127.
https://doi.org/10.1182/blood-2015-06-649905
Published: 2015
Includes: Supplemental data