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Severe chronic primary neutropenia in adults: report on a series of 108 patients
A multicenter randomized controlled trial of intravenous magnesium for sickle cell pain crisis in children
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Table of Contents
INSIDE BLOOD COMMENTARIES
CLINICAL TRIALS AND OBSERVATIONS
Severe chronic primary neutropenia in adults: report on a series of 108 patients
Clinical Trials & Observations
Flore Sicre de Fontbrune,for the French Severe Chronic Neutropenia Registry,Aline Moignet,for the French Severe Chronic Neutropenia Registry,Blandine Beaupain,for the French Severe Chronic Neutropenia Registry,Felipe Suarez,for the French Severe Chronic Neutropenia Registry,Lionel Galicier,for the French Severe Chronic Neutropenia Registry,Gérard Socié,for the French Severe Chronic Neutropenia Registry,Bruno Varet,for the French Severe Chronic Neutropenia Registry,Paul Coppo,for the French Severe Chronic Neutropenia Registry,Marc Michel,for the French Severe Chronic Neutropenia Registry,Cécile Pautas,for the French Severe Chronic Neutropenia Registry,Eric Oksenhendler,for the French Severe Chronic Neutropenia Registry,Etienne Lengline,for the French Severe Chronic Neutropenia Registry,Louis Terriou,for the French Severe Chronic Neutropenia Registry,Philippe Moreau,for the French Severe Chronic Neutropenia Registry,Sylvain Chantepie,for the French Severe Chronic Neutropenia Registry,Nicole Casadevall,for the French Severe Chronic Neutropenia Registry,Jean Marie Michot,for the French Severe Chronic Neutropenia Registry,Martine Gardembas,for the French Severe Chronic Neutropenia Registry,Mauricette Michallet,for the French Severe Chronic Neutropenia Registry,Laure Croisille,for the French Severe Chronic Neutropenia Registry,Marie Audrain,for the French Severe Chronic Neutropenia Registry,Christine Bellanné-Chantelot,for the French Severe Chronic Neutropenia Registry,Jean Donadieu,for the French Severe Chronic Neutropenia Registry,Thierry Lamy,for the French Severe Chronic Neutropenia Registry
A multicenter randomized controlled trial of intravenous magnesium for sickle cell pain crisis in children
Clinical Trials & Observations
David C. Brousseau,for the Pediatric Emergency Care Applied Research Network (PECARN),J. Paul Scott,for the Pediatric Emergency Care Applied Research Network (PECARN),Oluwakemi Badaki-Makun,for the Pediatric Emergency Care Applied Research Network (PECARN),Deepika S. Darbari,for the Pediatric Emergency Care Applied Research Network (PECARN),Corrie E. Chumpitazi,for the Pediatric Emergency Care Applied Research Network (PECARN),Gladstone E. Airewele,for the Pediatric Emergency Care Applied Research Network (PECARN),Angela M. Ellison,for the Pediatric Emergency Care Applied Research Network (PECARN),Kim Smith-Whitley,for the Pediatric Emergency Care Applied Research Network (PECARN),Prashant Mahajan,for the Pediatric Emergency Care Applied Research Network (PECARN),Sharada A. Sarnaik,for the Pediatric Emergency Care Applied Research Network (PECARN),T. Charles Casper,for the Pediatric Emergency Care Applied Research Network (PECARN),Lawrence J. Cook,for the Pediatric Emergency Care Applied Research Network (PECARN),J. Michael Dean,for the Pediatric Emergency Care Applied Research Network (PECARN),Julie Leonard,for the Pediatric Emergency Care Applied Research Network (PECARN),Monica L. Hulbert,for the Pediatric Emergency Care Applied Research Network (PECARN),Elizabeth C. Powell,for the Pediatric Emergency Care Applied Research Network (PECARN),Robert I. Liem,for the Pediatric Emergency Care Applied Research Network (PECARN),Robert Hickey,for the Pediatric Emergency Care Applied Research Network (PECARN),Lakshmanan Krishnamurti,for the Pediatric Emergency Care Applied Research Network (PECARN),Cheryl A. Hillery,for the Pediatric Emergency Care Applied Research Network (PECARN),Mark Nimmer,for the Pediatric Emergency Care Applied Research Network (PECARN),Julie A. Panepinto,for the Pediatric Emergency Care Applied Research Network (PECARN)
IMMUNOBIOLOGY
Omenn syndrome associated with a functional reversion due to a somatic second-site mutation in CARD11 deficiency
Sebastian Fuchs,Anne Rensing-Ehl,Ulrich Pannicke,Myriam R. Lorenz,Paul Fisch,Yogesh Jeelall,Jan Rohr,Carsten Speckmann,Thomas Vraetz,Susan Farmand,Annette Schmitt-Graeff,Marcus Krüger,Brigitte Strahm,Philipp Henneke,Anselm Enders,Keisuke Horikawa,Christopher Goodnow,Klaus Schwarz,Stephan Ehl
LYMPHOID NEOPLASIA
MYELOID NEOPLASIA
PLATELETS AND THROMBOPOIESIS
THROMBOSIS AND HEMOSTASIS
Platelet-derived VWF is not essential for normal thrombosis and hemostasis but fosters ischemic stroke injury in mice
Sebastien Verhenne,Frederik Denorme,Sarah Libbrecht,Aline Vandenbulcke,Inge Pareyn,Hans Deckmyn,Antoon Lambrecht,Bernhard Nieswandt,Christoph Kleinschnitz,Karen Vanhoorelbeke,Simon F. De Meyer
TRANSPLANTATION
Low urinary indoxyl sulfate levels early after transplantation reflect a disrupted microbiome and are associated with poor outcome
Daniela Weber,Peter J. Oefner,Andreas Hiergeist,Josef Koestler,André Gessner,Markus Weber,Joachim Hahn,Daniel Wolff,Frank Stämmler,Rainer Spang,Wolfgang Herr,Katja Dettmer,Ernst Holler
BLOOD WORK
CORRESPONDENCE
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Cover Image
Cover Image
Representative image of megakaryocytes deficient in the anaphase-promoting complex/cyclosome (APC/C) subunit Cdc20. In the absence of Cdc20, these giant cells arrest in mitosis with condensed chromosomes (as shown by phosphorylation of histone H3; magenta) and multipolar spindles (bright green within the magenta areas). DNA is shown in blue and tubulin is shown in green. The authors describe how megakaryocytes display a functional mitotic checkpoint that senses spindle aberrations leading to mitotic arrest. See the article by Trakala et al on page 1707.
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