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Issue Archive

Volume 125, Issue 24
June 11 2015
Issue Cover

Table of Contents

INSIDE BLOOD COMMENTARIES

INSIDE BLOOD COMMENTARY
Following aggressive B-cell lymphoma
John W. Sweetenham
View Articletitled, Following aggressive B-cell lymphoma
INSIDE BLOOD COMMENTARY
Time to tune the treatment of Ph+ ALL
Clinical Trials & Observations
Masamitsu Yanada
View Articletitled, Time to tune the treatment of Ph+ ALL
INSIDE BLOOD COMMENTARY
Improving survival for Fanconi anemia patients
Eliane Gluckman
View Articletitled, Improving survival for Fanconi anemia patients
INSIDE BLOOD COMMENTARY
Special delivery: microparticles convey heme
Gregory M. Vercellotti
View Articletitled, Special delivery: microparticles convey heme

PLENARY PAPER

PLENARY PAPER
Noninvasive monitoring of diffuse large B-cell lymphoma by immunoglobulin high-throughput sequencing
Clinical Trials & Observations
David M. Kurtz,Michael R. Green,Scott V. Bratman,Florian Scherer,Chih Long Liu,Christian A. Kunder,Kazuhiro Takahashi,Cynthia Glover,Colm Keane,Shingo Kihira,Brendan Visser,Jason Callahan,Katherine A. Kong,Malek Faham,Karen S. Corbelli,David Miklos,Ranjana H. Advani,Ronald Levy,Rodney J. Hicks,Mark Hertzberg,Robert S. Ohgami,Maher K. Gandhi,Maximilian Diehn,Ash A. Alizadeh
View Articletitled, Noninvasive monitoring of diffuse large B-cell lymphoma by immunoglobulin high-throughput sequencing
Supplemental data

BLOOD SPOTLIGHT

Rationale for targeting the pre–B-cell receptor signaling pathway in acute lymphoblastic leukemia
Markus Müschen
View Articletitled, Rationale for targeting the pre–B-cell receptor signaling pathway in acute lymphoblastic leukemia

REVIEW ARTICLE

α-Globin as a molecular target in the treatment of β-thalassemia
Sachith Mettananda,Richard J. Gibbons,Douglas R. Higgs
View Articletitled, α-Globin as a molecular target in the treatment of β-thalassemia

HOW I TREAT

How I treat acute lymphoblastic leukemia in older adolescents and young adults
Clinical Trials & Observations
Emily Curran,Wendy Stock
View Articletitled, How I treat acute lymphoblastic leukemia in older adolescents and young adults

CLINICAL TRIALS AND OBSERVATIONS

Randomized study of reduced-intensity chemotherapy combined with imatinib in adults with Ph-positive acute lymphoblastic leukemia
Clinical Trials & Observations
Yves Chalandon,Xavier Thomas,Sandrine Hayette,Jean-Michel Cayuela,Claire Abbal,Françoise Huguet,Emmanuel Raffoux,Thibaut Leguay,Philippe Rousselot,Stéphane Lepretre,Martine Escoffre-Barbe,Sébastien Maury,Céline Berthon,Emmanuelle Tavernier,Jean-François Lambert,Marina Lafage-Pochitaloff,Véronique Lhéritier,Sylvie Chevret,Norbert Ifrah,Hervé Dombret,for the Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL)
View Articletitled, Randomized study of reduced-intensity chemotherapy combined with imatinib in adults with Ph-positive acute lymphoblastic leukemia
Supplemental data

IMMUNOBIOLOGY

Altered lymphopoiesis and immunodeficiency in miR-142 null mice
Nicholas J. Kramer,Wei-Le Wang,Estefany Y. Reyes,Bijender Kumar,Ching-Cheng Chen,Chandran Ramakrishna,Edouard M. Cantin,Steven L. Vonderfecht,Konstantin D. Taganov,Nelson Chau,Mark P. Boldin
View Articletitled, Altered lymphopoiesis and immunodeficiency in <em>miR-142</em> null mice
Supplemental data

LYMPHOID NEOPLASIA

Overexpression of the shortest isoform of histone demethylase LSD1 primes hematopoietic stem cells for malignant transformation
Taeko Wada,Daisuke Koyama,Jiro Kikuchi,Hiroaki Honda,Yusuke Furukawa
View Articletitled, Overexpression of the shortest isoform of histone demethylase LSD1 primes hematopoietic stem cells for malignant transformation
Supplemental data
Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A
Francesca Zonta,Mario Angelo Pagano,Livio Trentin,Elena Tibaldi,Federica Frezzato,Valentina Trimarco,Monica Facco,Giuseppe Zagotto,Valeria Pavan,Giovanni Ribaudo,Luciana Bordin,Gianpietro Semenzato,Anna Maria Brunati
View Articletitled, Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A
Supplemental data
Evidence of an epigenetic origin for high-risk 1q21 copy number aberrations in multiple myeloma
Brief Report
Jeffrey R. Sawyer,Erming Tian,Christoph J. Heuck,Donald J. Johann,Joshua Epstein,Charles M. Swanson,Janet L. Lukacs,Regina Lichti Binz,Marian Johnson,Gael Sammartino,Maurizio Zangari,Faith E. Davies,Frits van Rhee,Gareth J. Morgan,Bart Barlogie
View Articletitled, Evidence of an epigenetic origin for high-risk 1q21 copy number aberrations in multiple myeloma
Supplemental data

MYELOID NEOPLASIA

RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates fasudil as an antileukemic drug
Martin Wermke,Aylin Camgoz,Maciej Paszkowski-Rogacz,Sebastian Thieme,Malte von Bonin,Andreas Dahl,Uwe Platzbecker,Mirko Theis,Gerhard Ehninger,Sebastian Brenner,Martin Bornhäuser,Frank Buchholz
View Articletitled, RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates fasudil as an antileukemic drug
Supplemental data

PLATELETS AND THROMBOPOIESIS

Podoplanin and CLEC-2 drive cerebrovascular patterning and integrity during development
Kate L. Lowe,Brenda A. Finney,Carsten Deppermann,René Hägerling,Salomé L. Gazit,Jon Frampton,Christopher Buckley,Eric Camerer,Bernhard Nieswandt,Friedemann Kiefer,Steve P. Watson
View Articletitled, Podoplanin and CLEC-2 drive cerebrovascular patterning and integrity during development
Supplemental data

TRANSPLANTATION

Myxoma virus suppresses proliferation of activated T lymphocytes yet permits oncolytic virus transfer to cancer cells
Nancy Y. Villa,Clive H. Wasserfall,Amy M. Meacham,Elizabeth Wise,Winnie Chan,John R. Wingard,Grant McFadden,Christopher R. Cogle
View Articletitled, Myxoma virus suppresses proliferation of activated T lymphocytes yet permits oncolytic virus transfer to cancer cells
Supplemental data
Idiopathic pneumonia syndrome after hematopoietic cell transplantation: evidence of occult infectious etiologies
Clinical Trials & Observations
Sachiko Seo,Christian Renaud,Jane M. Kuypers,Charles Y. Chiu,Meei-Li Huang,Erik Samayoa,Hu Xie,Guixia Yu,Cynthia E. Fisher,Ted A. Gooley,Steven Miller,Robert C. Hackman,David Myerson,Ruth H. Sedlak,Yae-Jean Kim,Takahiro Fukuda,David N. Fredricks,David K. Madtes,Keith R. Jerome,Michael Boeckh
View Articletitled, Idiopathic pneumonia syndrome after hematopoietic cell transplantation: evidence of occult infectious etiologies
Supplemental data
Alternative donor hematopoietic cell transplantation for Fanconi anemia
Margaret L. MacMillan,Todd E. DeFor,Jo-Anne H. Young,Kathryn E. Dusenbery,Bruce R. Blazar,Arne Slungaard,Heather Zierhut,Daniel J. Weisdorf,John E. Wagner
View Articletitled, Alternative donor hematopoietic cell transplantation for Fanconi anemia

VASCULAR BIOLOGY

Circulating cell membrane microparticles transfer heme to endothelial cells and trigger vasoocclusions in sickle cell disease
Stéphane M. Camus,João A. De Moraes,Philippe Bonnin,Paul Abbyad,Sylvain Le Jeune,François Lionnet,Laurent Loufrani,Linda Grimaud,Jean-Christophe Lambry,Dominique Charue,Laurent Kiger,Jean-Marie Renard,Claire Larroque,Hervé Le Clésiau,Alain Tedgui,Patrick Bruneval,Christina Barja-Fidalgo,Antigoni Alexandrou,Pierre-Louis Tharaux,Chantal M. Boulanger,Olivier P. Blanc-Brude
View Articletitled, Circulating cell membrane microparticles transfer heme to endothelial cells and trigger vasoocclusions in sickle cell disease
Supplemental data

BLOOD WORK

Misleading acute promyelocytic leukemia morphology
Soraya Wuillème,Yannick Le Bris
View Articletitled, Misleading acute promyelocytic leukemia morphology

CORRESPONDENCE

Reflections on the FranceCoag report on inhibitory antibodies to factor VIII in patients with severe hemophilia A
Clinical Trials & Observations
Erik Berntorp,Alfonso Iorio
View Articletitled, Reflections on the FranceCoag report on inhibitory antibodies to factor VIII in patients with severe hemophilia A
Response: Confounding by indication is unlikely to explain the higher inhibitor incidence in boys treated with a recombinant FVIII product
Clinical Trials & Observations
Thierry Calvez,Hervé Chambost,Patrick Lutz,Chantal Rothschild,Jenny Goudemand
View Articletitled, Response: Confounding by indication is unlikely to explain the higher inhibitor incidence in boys treated with a recombinant FVIII product
Supplemental data
Risk of inhibitors in previously untreated patients with hemophilia: a meta-analysis of literature studies
Clinical Trials & Observations
Matteo Nicola Dario Di Minno,Emanuela Marchesini,Lelia Valdrè
View Articletitled, Risk of inhibitors in previously untreated patients with hemophilia: a meta-analysis of literature studies
Lactate dehydrogenase isoenzyme 3 and hemolysis in sickle cell anemia: a possible correlation?
Grazielle Mecabo,Mihoko Yamamoto,Thais Priscila Biassi,Maria Stella Figueiredo
View Articletitled, Lactate dehydrogenase isoenzyme 3 and hemolysis in sickle cell anemia: a possible correlation?

ERRATA

Rivetti di Val Cervo P, Tucci P, Majid A, et al. p73, miR106b, miR34a, and Itch in chronic lymphocytic leukemia. Blood. 2009;113(25):6498-6499.
View Articletitled, Rivetti di Val Cervo P, Tucci P, Majid A, et al. p73, miR106b, miR34a, and Itch in chronic lymphocytic leukemia. <em>Blood</em>. 2009;113(25):6498-6499.
Yao H, Duan M, Buch S. Cocaine-mediated induction of platelet-derived growth factor: implication for increased vascular permeability. Blood. 2011;117(8):2538-2547.
View Articletitled, Yao H, Duan M, Buch S. Cocaine-mediated induction of platelet-derived growth factor: implication for increased vascular permeability. <em>Blood</em>. 2011;117(8):2538-2547.
Bishton MJ, Harrison SJ, Martin BP, et al. Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor–induced thrombocytopenia. Blood. 2011;117(13):3658-3668.
View Articletitled, Bishton MJ, Harrison SJ, Martin BP, et al. Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor–induced thrombocytopenia. <em>Blood</em>. 2011;117(13):3658-3668.
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