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Journal Articles

RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates fasudil as an antileukemic drug

Martin Wermke, Aylin Camgoz, Maciej Paszkowski-Rogacz, Sebastian Thieme, Malte von Bonin, Andreas Dahl, Uwe Platzbecker, Mirko Theis, Gerhard Ehninger, Sebastian Brenner, Martin Bornhäuser, Frank Buchholz
Journal: Blood
Blood (2015) 125 (24): 3760–3768.
https://doi.org/10.1182/blood-2014-07-590646
Published: 2015
Includes: Supplemental data
Journal Articles

A Genome Wide shRNA Screen In Primary Human AML Cells Identifies ROCK1 As a Novel Therapeutic Target

Martin Wermke, MD, Aylin Camgoz, Maciej Paszkowski-Rogacz, PhD, Sebastian Thieme, PhD, Malte von Bonin, MD, Andreas Dahl, PhD, Mirko Theis, PhD, Gerhard Ehninger, MD, Sebastian Brenner, MD, Martin Bornhäuser, MD, Frank Buchholz, PhD
Journal: Blood
Blood (2013) 122 (21): 170.
https://doi.org/10.1182/blood.V122.21.170.170
Published: 2013
Journal Articles

Runx1 is essential at two stages of early murine B-cell development

Birte Niebuhr, Neele Kriebitzsch, Meike Fischer, Kira Behrens, Thomas Günther, Malik Alawi, Ulla Bergholz, Ursula Müller, Susanne Roscher, Marion Ziegler, Frank Buchholz, Adam Grundhoff, Carol Stocking
Journal: Blood
Blood (2013) 122 (3): 413–423.
https://doi.org/10.1182/blood-2013-01-480244
Published: 2013
Includes: Supplemental data
Journal Articles

The histone demethylase UTX regulates stem cell migration and hematopoiesis

Sebastian Thieme, Tobias Gyárfás, Cornelia Richter, Günes Özhan, Jun Fu, Dimitra Alexopoulou, Michael H. Muders, Irene Michalk, Christiane Jakob, Andreas Dahl, Barbara Klink, Joanna Bandoła, Michael Bachmann, Evelin Schröck, Frank Buchholz, A. Francis Stewart, Gilbert Weidinger, Konstantinos Anastassiadis, Sebastian Brenner
Journal: Blood
Blood (2013) 121 (13): 2462–2473.
https://doi.org/10.1182/blood-2012-08-452003
Published: 2013
Includes: Supplemental data
Journal Articles

Polycomb group ring finger 1 cooperates with Runx1 in regulating differentiation and self-renewal of hematopoietic cells

Katharina Ross, Anna K. Sedello, Gabriele Putz Todd, Maciej Paszkowski-Rogacz, Alexander W. Bird, Li Ding, Tatyana Grinenko, Kira Behrens, Nina Hubner, Matthias Mann, Claudia Waskow, Carol Stocking, Frank Buchholz
Journal: Blood
Blood (2012) 119 (18): 4152–4161.
https://doi.org/10.1182/blood-2011-09-382390
Published: 2012
Includes: Supplemental data
Journal Articles

The Role of RUNX1 DNA-Binding Mutations in Acute Myeloid Leukemia.

Jorg Cammenga, MD, Gabriela Putz, PhD, Birte Niebuhr, MS/BS, Stefan Horn, PhD, Ulla Bergholz, Frank Buchholz, PhD, Carol Stocking, PhD
Journal: Blood
Blood (2005) 106 (11): 1373.
https://doi.org/10.1182/blood.V106.11.1373.1373
Published: 2005