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Randomized trial comparing liposomal daunorubicin with idarubicin as induction for pediatric acute myeloid leukemia: results from Study AML-BFM 2004
Defects in neutrophil granule mobilization and bactericidal activity in familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) syndrome caused by STXBP2/Munc18-2 mutations
Issue Archive
July 4 2013
In this Issue
Table of Contents
EDITORIAL
INSIDE BLOOD
BLOOD WORK
PLENARY PAPER
BLOOD SPOTLIGHT
REVIEW ARTICLE
CLINICAL TRIALS AND OBSERVATIONS
Randomized trial comparing liposomal daunorubicin with idarubicin as induction for pediatric acute myeloid leukemia: results from Study AML-BFM 2004
Clinical Trials & Observations
Ursula Creutzig,Martin Zimmermann,Jean-Pierre Bourquin,Michael N. Dworzak,Gudrun Fleischhack,Norbert Graf,Thomas Klingebiel,Bernhard Kremens,Thomas Lehrnbecher,Christine von Neuhoff,Jörg Ritter,Annette Sander,André Schrauder,Arend von Stackelberg,Jan Starý,Dirk Reinhardt
HEMATOPOIESIS AND STEM CELLS
IMMUNOBIOLOGY
LYMPHOID NEOPLASIA
Outcomes of patients with POEMS syndrome treated initially with radiation
Michael S. Humeniuk,Morie A. Gertz,Martha Q. Lacy,Robert A. Kyle,Thomas E. Witzig,Shaji K. Kumar,Prashant Kapoor,John A. Lust,Suzanne R. Hayman,Francis K. Buadi,S. Vincent Rajkumar,Steven R. Zeldenrust,Stephen J. Russell,David Dingli,Yi Lin,Nelson Leung,Angela Dispenzieri
MYELOID NEOPLASIA
The level of residual disease based on mutant NPM1 is an independent prognostic factor for relapse and survival in AML
Nona Shayegi,Michael Kramer,Martin Bornhäuser,Markus Schaich,Johannes Schetelig,Uwe Platzbecker,Christoph Röllig,Caroline Heiderich,Olfert Landt,Gerhard Ehninger,Christian Thiede,on behalf of the Study Alliance Leukemia (SAL)
Clonal evolution in relapsed NPM1-mutated acute myeloid leukemia
Jan Krönke,Lars Bullinger,Veronica Teleanu,Florian Tschürtz,Verena I. Gaidzik,Michael W. M. Kühn,Frank G. Rücker,Karlheinz Holzmann,Peter Paschka,Silke Kapp-Schwörer,Daniela Späth,Thomas Kindler,Marcus Schittenhelm,Jürgen Krauter,Arnold Ganser,Gudrun Göhring,Brigitte Schlegelberger,Richard F. Schlenk,Hartmut Döhner,Konstanze Döhner
PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS
Defects in neutrophil granule mobilization and bactericidal activity in familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) syndrome caused by STXBP2/Munc18-2 mutations
Brief Report
Xi Wen Zhao,Roel P. Gazendam,Agata Drewniak,Michel van Houdt,Anton T. J. Tool,John L. van Hamme,Iwan Kustiawan,Alexander B. Meijer,Hans Janssen,David G. Russell,Lisette van de Corput,Kiki Tesselaar,Jaap J. Boelens,Ingrid Kuhnle,Jutte Van Der Werff Ten Bosch,Taco W. Kuijpers,Timo K. van den Berg
RED CELLS, IRON, AND ERYTHROPOIESIS
A novel syndrome of congenital sideroblastic anemia, B-cell immunodeficiency, periodic fevers, and developmental delay (SIFD)
Daniel H. Wiseman,Alison May,Stephen Jolles,Philip Connor,Colin Powell,Matthew M. Heeney,Patricia J. Giardina,Robert J. Klaassen,Pranesh Chakraborty,Michael T. Geraghty,Nathalie Major-Cook,Caroline Kannengiesser,Isabelle Thuret,Alexis A. Thompson,Laura Marques,Stephen Hughes,Denise K. Bonney,Sylvia S. Bottomley,Mark D. Fleming,Robert F. Wynn
THROMBOSIS AND HEMOSTASIS
Diabetes is associated with posttranslational modifications in plasminogen resulting in reduced plasmin generation and enzyme-specific activity
Ramzi A. Ajjan,Toby Gamlen,Kristina F. Standeven,Salihah Mughal,Katharina Hess,Kerrie A. Smith,Emma J. Dunn,M. Maqsud Anwar,Naila Rabbani,Paul J. Thornalley,Helen Philippou,Peter J. Grant
VASCULAR BIOLOGY
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Cover Image
Cover Image
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Perls stained bone marrow aspirate particle from a child with sideroblastic anemia, B-cell immunodeficiency, fevers, and developmental delay (SIFD): a newly-described syndromic form of congenital sideroblastic anemia. Particle shows gross iron overload, with higher power magnification revealing >50% of erythroid precursors as ring sideroblasts. The child also displayed hypogammaglobulinemia, B-lymphopenia, periodic inflammatory episodes, and developmental delay. See the article by Wiseman et al on page 112.
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