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Journal Articles

Factor VIII–driven changes in activated factor IX explored by hydrogen-deuterium exchange mass spectrometry

Nadia Freato, Eduard H. T. M. Ebberink, Josse van Galen, Caroline Fribourg, Mariëtte Boon-Spijker, Floris P. J. van Alphen, Alexander B. Meijer, Maartje van den Biggelaar, Koen Mertens

Blood (2020) 136 (23): 2703–2714.

https://doi.org/10.1182/blood.2020005593

Published: 2020

Includes: Supplemental data

Journal Articles

The Macrophage-Specific CD163 Is an Endocytic Receptor for Von Willebrand Factor (VWF) Cleaving Protease ADAMTS13

Fabian Verbij, MSc, Nicoletta Sorvillo, PhD, Paul Kaijen, Johana Hrdinova, MSc, Rob Fijnheer, MD PhD, Anja ten Brinke, PhD, Alexander B. Meijer, PhD, Floris P. van Alphen, BSc, Timo K. van der Berg, Dr., Jonas H. Graversen, Soren K. Moestrup, MD PhD, Jan Voorberg, PhD

Blood (2016) 128 (22): 17.

https://doi.org/10.1182/blood.V128.22.17.17

Published: 2016

Journal Articles

Label Free Quantitative Mass Spectrometry Identifies Processes Linked to Platelet Degranulation As Early Events during Platelet Storage

Maaike Rijkers, Floris P. van Alphen, BSc, Pieter F. van der Meer, PhD, Dirk de Korte, PhD, Frank W.G. Leebeek, MD PhD, Alexander B. Meijer, PhD, Jan Voorberg, PhD, Gerard AJG Jansen, MD PhD

Blood (2016) 128 (22): 2638.

https://doi.org/10.1182/blood.V128.22.2638.2638

Published: 2016

Journal Articles

Megakaryocyte Expansion and Platelet CD34 Expression Observed in GFI1B Q287* -Related Bleeding and Platelet Disorder Is Caused By Quenching of the Lysine Specific Demethylase LSD1/KDM1A

Rinske van Oorschot, MSc, Anna E. Marneth, MSc, Marten Hansen, BSc, Saskia M. Bergevoet, Alexander B. Meijer, PhD, Britta A.P. Laros-van-Gorkom, MD PhD, Joop H. Jansen, PhD, Marieke Von Lindern, PhD, Emile van den Akker, PhD, Bert A. van der Reijden, PhD

Blood (2016) 128 (22): 363.

https://doi.org/10.1182/blood.V128.22.363.363

Published: 2016

Journal Articles

Identification of glycans on plasma-derived ADAMTS13

Fabian C. Verbij, Eva Stokhuijzen, Paul H. P. Kaijen, Floris van Alphen, Alexander B. Meijer, Jan Voorberg

Blood (2016) 128 (21): e51–e58.

https://doi.org/10.1182/blood-2016-06-720912

Published: 2016

Includes: Supplemental data

Journal Articles

Quantitative phosphoproteomics unveils temporal dynamics of thrombin signaling in human endothelial cells

Maartje van den Biggelaar, Juan Ramon Hernández-Fernaud, Bart L. van den Eshof, Lisa J. Neilson, Alexander B. Meijer, Koen Mertens, Sara Zanivan

Blood (2014) 123 (12): e22–e36.

https://doi.org/10.1182/blood-2013-12-546036

Published: 2014

Includes: Supplemental data

Journal Articles

Defects in neutrophil granule mobilization and bactericidal activity in familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) syndrome caused by STXBP2/Munc18-2 mutations

Xi Wen Zhao, Roel P. Gazendam, Agata Drewniak, Michel van Houdt, Anton T. J. Tool, John L. van Hamme, Iwan Kustiawan, Alexander B. Meijer, Hans Janssen, David G. Russell, Lisette van de Corput, Kiki Tesselaar, Jaap J. Boelens, Ingrid Kuhnle, Jutte Van Der Werff Ten Bosch, Taco W. Kuijpers, Timo K. van den Berg

Blood (2013) 122 (1): 109–111.

https://doi.org/10.1182/blood-2013-03-494039

Published: 2013

Includes: Supplemental data

Journal Articles

Preferential HLA-DRB1*11–dependent presentation of CUB2-derived peptides by ADAMTS13-pulsed dendritic cells

Nicoletta Sorvillo, Simon D. van Haren, Paul H. Kaijen, Anja ten Brinke, Rob Fijnheer, Alexander B. Meijer, Jan Voorberg

Blood (2013) 121 (17): 3502–3510.

https://doi.org/10.1182/blood-2012-09-456780

Published: 2013

Includes: Supplemental data

Journal Articles

Factor VIII Region 1811–1818 Is Involved in Factor IXa Binding and Factor VIIIa Stability

Esther Bloem, Msc, Henriet Meems, PhD, Maartje van den Biggelaar, PhD, Koen Mertens, PhD, Alexander B Meijer, PhD

Blood (2012) 120 (21): 3357.

https://doi.org/10.1182/blood.V120.21.3357.3357

Published: 2012

Journal Articles

Preferential HLA-DRB1*11 Dependent Presentation of CUB2 Derived Peptides by ADAMTS13 Pulsed Dendritic Cells

Nicoletta Sorvillo, Simon D. van Haren, Paul H. Kaijen, Anja ten Brinke, PhD, Rob Fijnheer, Alexander B. Meijer, Jan Voorberg, PhD

Blood (2012) 120 (21): 489.

https://doi.org/10.1182/blood.V120.21.489.489

Published: 2012

Journal Articles

Factors VIII and V swap fatty feet

Koen Mertens, Alexander B. Meijer

Blood (2012) 120 (9): 1761–1763.

https://doi.org/10.1182/blood-2012-07-434027

Published: 2012

Journal Articles

Modification of an exposed loop in the C1 domain reduces immune responses to factor VIII in hemophilia A mice

Aleksandra Wroblewska, Simon D. van Haren, Eszter Herczenik, Paul Kaijen, Aleksandra Ruminska, Sheng-Yu Jin, X. Long Zheng, Maartje van den Biggelaar, Anja ten Brinke, Alexander B. Meijer, Jan Voorberg

Blood (2012) 119 (22): 5294–5300.

https://doi.org/10.1182/blood-2011-11-391680

Published: 2012

Includes: Supplemental data

Journal Articles

The N-Terminal Amino Acid Residues Ser764 and Lys773 of the D' Domain of Von Willebrand Factor Contribute to Factor VIII Binding

Lydia Castro-Núñez, Esther Bloem, Carmen van der Zwaan, Koen Mertens, PhD, Alexander B Meijer

Blood (2011) 118 (21): 2248.

https://doi.org/10.1182/blood.V118.21.2248.2248

Published: 2011

Journal Articles

C-Type Lectin Receptor Mediated Immune Recognition of ADAMTS13 Promotes HLA-DRB1*11 Dependent Presentation of CUB1-2 Derived Peptides by Dendritic Cells

Nicoletta Sorvillo, Simon D van Haren, Wouter Pos, Eszter Herczenik, Rob Fijnheer, Luisa Martinez-Pomares, Teunis B Geijtenbeek, Alexander B Meijer, Jan Voorberg

Blood (2011) 118 (21): 196.

https://doi.org/10.1182/blood.V118.21.196.196

Published: 2011

Journal Articles

Factor VII Activating Protease (FSAP): Functional Implications of the “Marburg-1” Polymorphism.

Fabian Stavenuiter, Alexander B Meijer, Erica Sellink, Koen Mertens

Blood (2009) 114 (22): 2126.

https://doi.org/10.1182/blood.V114.22.2126.2126

Published: 2009

Journal Articles

Factor VIII C1 domain residues Lys 2092 and Phe 2093 contribute to membrane binding and cofactor activity

Henriët Meems, Alexander B. Meijer, David B. Cullinan, Koen Mertens, Gary E. Gilbert

Blood (2009) 114 (18): 3938–3946.

https://doi.org/10.1182/blood-2009-01-197707

Published: 2009

Journal Articles

Intracellular cotrafficking of factor VIII and von Willebrand factor type 2N variants to storage organelles

Maartje van den Biggelaar, Alexander B. Meijer, Jan Voorberg, Koen Mertens

Blood (2009) 113 (13): 3102–3109.

https://doi.org/10.1182/blood-2008-05-159699

Published: 2009

Journal Articles

Factor VIII C1 Domain Residues 2092–2093 Participate in Membrane Binding

Henriet Meems, Alexander B Meijer, Dave Cullinan, Koen Mertens, PhD, Gary E. Gilbert

Blood (2008) 112 (11): 587.

https://doi.org/10.1182/blood.V112.11.587.587

Published: 2008

Journal Articles

PEGylation or Polysialylation Reduces FVIII Binding to LRP Resulting in Prolonged Half-Life in Murine Models.

Hanspeter Rottensteiner, Peter L. Turecek, PhD, Rona Pendu, Alexander B. Meijer, Peter Lenting, Koen Mertens, PhD, Eva-Maria Muchitsch, DVM, Hartmut Ehrlich, MD, Hans Peter Schwarz, MD

Blood (2007) 110 (11): 3150.

https://doi.org/10.1182/blood.V110.11.3150.3150

Published: 2007

Journal Articles

Somatic Mutations in Factor VIII Inhibitors Determine Their Factor VIII Binding and Inhibitory Properties.

Koen Mertens, PhD, David Gestel, Gunny van Stempvoort, Vincent Limburg, Ed E. Moret, PhD, Alexander B. Meijer, PhD

Blood (2007) 110 (11): 1762.

https://doi.org/10.1182/blood.V110.11.1762.1762

Published: 2007

NARROW

Factor VIII–driven changes in activated factor IX explored by hydrogen-deuterium exchange mass spectrometry

The Macrophage-Specific CD163 Is an Endocytic Receptor for Von Willebrand Factor (VWF) Cleaving Protease ADAMTS13

Label Free Quantitative Mass Spectrometry Identifies Processes Linked to Platelet Degranulation As Early Events during Platelet Storage

Megakaryocyte Expansion and Platelet CD34 Expression Observed in GFI1B Q287* -Related Bleeding and Platelet Disorder Is Caused By Quenching of the Lysine Specific Demethylase LSD1/KDM1A

Identification of glycans on plasma-derived ADAMTS13

Quantitative phosphoproteomics unveils temporal dynamics of thrombin signaling in human endothelial cells

Defects in neutrophil granule mobilization and bactericidal activity in familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) syndrome caused by STXBP2/Munc18-2 mutations

Preferential HLA-DRB1*11–dependent presentation of CUB2-derived peptides by ADAMTS13-pulsed dendritic cells

Factor VIII Region 1811–1818 Is Involved in Factor IXa Binding and Factor VIIIa Stability

Preferential HLA-DRB1*11 Dependent Presentation of CUB2 Derived Peptides by ADAMTS13 Pulsed Dendritic Cells

Factors VIII and V swap fatty feet

Modification of an exposed loop in the C1 domain reduces immune responses to factor VIII in hemophilia A mice

The N-Terminal Amino Acid Residues Ser764 and Lys773 of the D' Domain of Von Willebrand Factor Contribute to Factor VIII Binding

C-Type Lectin Receptor Mediated Immune Recognition of ADAMTS13 Promotes HLA-DRB1*11 Dependent Presentation of CUB1-2 Derived Peptides by Dendritic Cells

Factor VII Activating Protease (FSAP): Functional Implications of the “Marburg-1” Polymorphism.

Factor VIII C1 domain residues Lys 2092 and Phe 2093 contribute to membrane binding and cofactor activity

Intracellular cotrafficking of factor VIII and von Willebrand factor type 2N variants to storage organelles

Factor VIII C1 Domain Residues 2092–2093 Participate in Membrane Binding

PEGylation or Polysialylation Reduces FVIII Binding to LRP Resulting in Prolonged Half-Life in Murine Models.

Somatic Mutations in Factor VIII Inhibitors Determine Their Factor VIII Binding and Inhibitory Properties.

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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