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Journal Articles

AAV-mediated expression of an ADAMTS13 variant prevents shigatoxin-induced thrombotic thrombocytopenic purpura

Brief Report
Sheng-Yu Jin, Juan Xiao, Jialing Bao, Shangzhen Zhou, J. Fraser Wright, X. Long Zheng
Journal: Blood
Blood (2013) 121 (19): 3825–3829.
https://doi.org/10.1182/blood-2013-02-486779
Published: 2013
Includes: Supplemental data
Journal Articles

Ectopic Expression of ADAMTS13 in Platelets As a Novel Therapeutic Approach for Arterial Thrombosis

Brandy Pickens, PhD, Sheng-Yu Jin, MD, PhD, Dengju Li, MD, PhD, X. Long Zheng, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 491.
https://doi.org/10.1182/blood.V120.21.491.491
Published: 2012
Journal Articles

Modification of an exposed loop in the C1 domain reduces immune responses to factor VIII in hemophilia A mice

Aleksandra Wroblewska, Simon D. van Haren, Eszter Herczenik, Paul Kaijen, Aleksandra Ruminska, Sheng-Yu Jin, X. Long Zheng, Maartje van den Biggelaar, Anja ten Brinke, Alexander B. Meijer, Jan Voorberg
Journal: Blood
Blood (2012) 119 (22): 5294–5300.
https://doi.org/10.1182/blood-2011-11-391680
Published: 2012
Includes: Supplemental data
Journal Articles

Gain-of-function ADAMTS13 variants that are resistant to autoantibodies against ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura

Cui Jian, Juan Xiao, Lingjie Gong, Christopher G. Skipwith, Sheng-Yu Jin, Hau C. Kwaan, X. Long Zheng
Journal: Blood
Blood (2012) 119 (16): 3836–3843.
https://doi.org/10.1182/blood-2011-12-399501
Published: 2012
Includes: Multimedia, Supplemental data
Journal Articles

Gain-of-Function ADAMTS13 Variants Resistant to Anti-ADAMTS13 Autoantibody Inhibition: A Potential Novel Therapy for Acquired Autoimmune Thrombotic Thrombocytopenic Purpura

Cui Jian, M.S., Juan (Jenny) Xiao, M.D., Ph.D., Lingjie Gong, M.D., Christopher G. Skipwith, Sheng-Yu Jin, M.D., Ph.D., Hau C. Kwaan, M.D., Ph.D., X. Long Zheng, M.D., Ph.D.
Journal: Blood
Blood (2011) 118 (21): 1188.
https://doi.org/10.1182/blood.V118.21.1188.1188
Published: 2011
Journal Articles

Multiple Carboxyl-Terminal Domains of ADAMTS13 Are Required for Systemic Anti-Arterial Thrombosis In Vivo

Juan (Jenny) Xiao, M.D., Ph.D., Sheng-Yu Jin, M.D., Ph.D., X. Long Zheng, M.D., Ph.D.
Journal: Blood
Blood (2010) 116 (21): 24.
https://doi.org/10.1182/blood.V116.21.24.24
Published: 2010
Journal Articles

Correction of ADAMTS13 Deficiency by AAV-Mediated Gene Transfer of a C-Terminal Truncated ADAMTS13 Variant In a Murine Model

Sheng-Yu Jin, M.D., Ph.D., Juan (Jenny) Xiao, M.D., Ph.D., J. Fraser Wright, Ph.D., X. Long Zheng, M.D., Ph.D.
Journal: Blood
Blood (2010) 116 (21): 251.
https://doi.org/10.1182/blood.V116.21.251.251
Published: 2010
Journal Articles

Amino acid residues Arg 659 , Arg 660 , and Tyr 661 in the spacer domain of ADAMTS13 are critical for cleavage of von Willebrand factor

Sheng-Yu Jin, Christopher G. Skipwith, X. Long Zheng
Journal: Blood
Blood (2010) 115 (11): 2300–2310.
https://doi.org/10.1182/blood-2009-07-235101
Published: 2010