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Floris P. J. van Alphen
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Journal Articles

N-glycan–mediated shielding of ADAMTS13 prevents binding of pathogenic autoantibodies in immune-mediated TTP

Brief Report
Bogac Ercig, Nuno A. G. Graça, Kadri Kangro, Tom Arfman, Kanin Wichapong, Johana Hrdinová, Paul Kaijen, Floris P. J. van Alphen, Maartje van den Biggelaar, Karen Vanhoorelbeke, Agnès Veyradier, Paul Coppo, Chris Reutelingsperger, Gerry A. F. Nicolaes, Andres Männik, Jan Voorberg
Journal: Blood
Blood (2021) 137 (19): 2694–2698.
https://doi.org/10.1182/blood.2020007972
Published: 2021
Includes: Multimedia, Supplemental data
Journal Articles

Factor VIII–driven changes in activated factor IX explored by hydrogen-deuterium exchange mass spectrometry

Nadia Freato, Eduard H. T. M. Ebberink, Josse van Galen, Caroline Fribourg, Mariëtte Boon-Spijker, Floris P. J. van Alphen, Alexander B. Meijer, Maartje van den Biggelaar, Koen Mertens
Journal: Blood
Blood (2020) 136 (23): 2703–2714.
https://doi.org/10.1182/blood.2020005593
Published: 2020
Includes: Supplemental data
Journal Articles

MKL1 deficiency results in a severe neutrophil motility defect due to impaired actin polymerization

Evelien G. G. Sprenkeler, Stefanie S. V. Henriet, Anton T. J. Tool, Iris C. Kreft, Ivo van der Bijl, Cathelijn E. M. Aarts, Michel van Houdt, Paul J. J. H. Verkuijlen, Koen van Aerde, Gerald Jaspers, Arno van Heijst, Wouter Koole, Thatjana Gardeitchik, Judy Geissler, Martin de Boer, Simon Tol, Christine W. Bruggeman, Floris P. J. van Alphen, Han J. M. P. Verhagen, Emile van den Akker, Hans Janssen, Robin van Bruggen, Timo K. van den Berg, Kian D. Liem, Taco W. Kuijpers
Journal: Blood
Blood (2020) 135 (24): 2171–2181.
https://doi.org/10.1182/blood.2019002633
Published: 2020
Includes: Multimedia, Supplemental data