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Journal Articles

IAP and HDAC inhibitors interact synergistically in myeloma cells through noncanonical NF-κB– and caspase-8–dependent mechanisms

Liang Zhou, Yu Zhang, Mark B. Meads, Yun Dai, Yanxia Ning, Xiaoyan Hu, Lin Li, Kanika Sharma, Jewel Nkwocha, Rebecca Parker, Danny Bui, Jacquelyn McCarter, Lora Kramer, Cullen Purcell, Praneeth R. Sudalagunta, Rafael R. Canevarolo, Maria D. Coelho Siqueira Silva, Gabriel De Avila, Raghunandan Reddy Alugubelli, Ariosto S. Silva, Maciej Kmeiciak, Andrea Ferreira-Gonzalez, Kenneth H. Shain, Steven Grant
Journal: Blood Advances
Blood Adv (2021) 5 (19): 3776–3788.
https://doi.org/10.1182/bloodadvances.2020003597
Published: 2021
Includes: Supplemental data
Journal Articles

RPS15 mutations rewire RNA translation in chronic lymphocytic leukemia

Stavroula Ntoufa, Marina Gerousi, Stamatia Laidou, Fotis Psomopoulos, Georgios Tsiolas, Theodoros Moysiadis, Nikos Papakonstantinou, Larry Mansouri, Achilles Anagnostopoulos, Niki Stavrogianni, Sarka Pospisilova, Karla Plevova, Antonios M. Makris, Richard Rosenquist, Kostas Stamatopoulos
Journal: Blood Advances
Blood Adv (2021) 5 (13): 2788–2792.
https://doi.org/10.1182/bloodadvances.2020001717
Published: 2021
Includes: Supplemental data
Journal Articles

G9a/GLP targeting in MM promotes autophagy-associated apoptosis and boosts proteasome inhibitor–mediated cell death

Eva De Smedt, Julie Devin, Catharina Muylaert, Nicolas Robert, Guilhem Requirand, Philip Vlummens, Laure Vincent, Guillaume Cartron, Ken Maes, Jerome Moreaux, Elke De Bruyne
Journal: Blood Advances
Blood Adv (2021) 5 (9): 2325–2338.
https://doi.org/10.1182/bloodadvances.2020003217
Published: 2021
Includes: Supplemental data
Journal Articles

ESRRB regulates glucocorticoid gene expression in mice and patients with acute lymphoblastic leukemia

Kayleigh M. Gallagher, Justine E. Roderick, Shi Hao Tan, Tze King Tan, Leonard Murphy, Jun Yu, Rui Li, Kevin W. O’Connor, Julie Zhu, Michael R. Green, Takaomi Sanda, Michelle A. Kelliher
Journal: Blood Advances
Blood Adv (2020) 4 (13): 3154–3168.
https://doi.org/10.1182/bloodadvances.2020001555
Published: 2020
Includes: Supplemental data
Journal Articles

Germline heterozygous mutations in Nxf1 perturb RNA metabolism and trigger thrombocytopenia and lymphopenia in mice

Stéphane Chappaz, Charity W. Law, Mark R. Dowling, Kirstyn T. Carey, Rachael M. Lane, Linh H. Ngo, Vihandha O. Wickramasinghe, Gordon K. Smyth, Matthew E. Ritchie, Benjamin T. Kile
Journal: Blood Advances
Blood Adv (2020) 4 (7): 1270–1283.
https://doi.org/10.1182/bloodadvances.2019001323
Published: 2020
Includes: Supplemental data
Journal Articles

The stem cell–specific long noncoding RNA HOXA10-AS in the pathogenesis of KMT2A -rearranged leukemia

Sina Al-Kershi, Raj Bhayadia, Michelle Ng, Lonneke Verboon, Stephan Emmrich, Lucie Gack, Adrian Schwarzer, Till Strowig, Dirk Heckl, Jan-Henning Klusmann
Journal: Blood Advances
Blood Adv (2019) 3 (24): 4252–4263.
https://doi.org/10.1182/bloodadvances.2019032029
Published: 2019
Includes: Supplemental data
Journal Articles

Sptlc1 is essential for myeloid differentiation and hematopoietic homeostasis

Velayoudame Parthibane, Diwash Acharya, Sargur Madabushi Srideshikan, Jing Lin, Dru G. Myerscough, Thiruvaimozhi Abimannan, Nagampalli Vijaykrishna, Daniel Blankenberg, Lavanya Bondada, Kimberly D. Klarmann, Stephen D. Fox, Thorkell Andresson, Lino Tessarollo, Usha Acharya, Jonathan R. Keller, Jairaj K. Acharya
Journal: Blood Advances
Blood Adv (2019) 3 (22): 3635–3649.
https://doi.org/10.1182/bloodadvances.2019000729
Published: 2019
Includes: Supplemental data
Journal Articles

Large-scale in vitro production of red blood cells from human peripheral blood mononuclear cells

Steven Heshusius, Esther Heideveld, Patrick Burger, Marijke Thiel-Valkhof, Erica Sellink, Eszter Varga, Elina Ovchynnikova, Anna Visser, Joost H. A. Martens, Marieke von Lindern, Emile van den Akker
Journal: Blood Advances
Blood Adv (2019) 3 (21): 3337–3350.
https://doi.org/10.1182/bloodadvances.2019000689
Published: 2019
Includes: Supplemental data
Journal Articles

Transcriptome analysis offers a comprehensive illustration of the genetic background of pediatric acute myeloid leukemia

Norio Shiba, Kenichi Yoshida, Yusuke Hara, Genki Yamato, Yuichi Shiraishi, Hidemasa Matsuo, Yusuke Okuno, Kenichi Chiba, Hiroko Tanaka, Taeko Kaburagi, Masanobu Takeuchi, Kentaro Ohki, Masashi Sanada, Jun Okubo, Daisuke Tomizawa, Tomohiko Taki, Akira Shimada, Manabu Sotomatsu, Keizo Horibe, Takashi Taga, Souichi Adachi, Akio Tawa, Satoru Miyano, Seishi Ogawa, Yasuhide Hayashi
Journal: Blood Advances
Blood Adv (2019) 3 (20): 3157–3169.
https://doi.org/10.1182/bloodadvances.2019000404
Published: 2019
Includes: Supplemental data
Journal Articles

Dynamins 2 and 3 control the migration of human megakaryocytes by regulating CXCR4 surface expression and ITGB1 activity

Praveen K. Suraneni, Seth J. Corey, Michael J. Hession, Rameez Ishaq, Arinola Awomolo, Shirin Hasan, Chirag Shah, Hui Liu, Amittha Wickrema, Najet Debili, John D. Crispino, Elizabeth A. Eklund, Yolande Chen
Journal: Blood Advances
Blood Adv (2018) 2 (23): 3540–3552.
https://doi.org/10.1182/bloodadvances.2018021923
Published: 2018
Includes: Multimedia, Supplemental data
Journal Articles

Transient loss of detectable HIV-1 RNA following brentuximab vedotin anti-CD30 therapy for Hodgkin lymphoma

Clinical Trials & Observations
Chia-Ching Wang, Cassandra Thanh, Erica A. Gibson, Maya Ball-Burack, Louise E. Hogan, Benjamin Descours, Norman Jones, Alexander B. Carvidi, Sadie Munter, Sonia Bakkour, Michael P. Busch, Jeffrey M. Milush, Steven G. Deeks, Timothy J. Henrich
Journal: Blood Advances
Blood Adv (2018) 2 (23): 3479–3482.
https://doi.org/10.1182/bloodadvances.2018024364
Published: 2018
Includes: Supplemental data
Journal Articles

The kinases IKBKE and TBK1 regulate MYC-dependent survival pathways through YB-1 in AML and are targets for therapy

Suhu Liu, Anna E. Marneth, Gabriela Alexe, Sarah R. Walker, Helen I. Gandler, Darwin Q. Ye, Katherine Labella, Radhika Mathur, Patricia A. Toniolo, Michelle Tillgren, Prafulla C. Gokhale, David Barbie, Ann Mullally, Kimberly Stegmaier, David A. Frank
Journal: Blood Advances
Blood Adv (2018) 2 (23): 3428–3442.
https://doi.org/10.1182/bloodadvances.2018016733
Published: 2018
Includes: Supplemental data
Journal Articles

HoxA9 transforms murine myeloid cells by a feedback loop driving expression of key oncogenes and cell cycle control genes

Xiaoxia Zhong, Andreas Prinz, Julia Steger, Maria-Paz Garcia-Cuellar, Markus Radsak, Abderrazzak Bentaher, Robert K. Slany
Journal: Blood Advances
Blood Adv (2018) 2 (22): 3137–3148.
https://doi.org/10.1182/bloodadvances.2018025866
Published: 2018
Includes: Supplemental data
Journal Articles

Mechanisms of establishment and functional significance of DNA demethylation during erythroid differentiation

Boris Bartholdy, Julien Lajugie, Zi Yan, Shouping Zhang, Rituparna Mukhopadhyay, John M. Greally, Masako Suzuki, Eric E. Bouhassira
Journal: Blood Advances
Blood Adv (2018) 2 (15): 1833–1852.
https://doi.org/10.1182/bloodadvances.2018015651
Published: 2018
Includes: Supplemental data
Journal Articles

Expression profiling of snoRNAs in normal hematopoiesis and AML

Wayne A. Warner, David H. Spencer, Maria Trissal, Brian S. White, Nichole Helton, Timothy J. Ley, Daniel C. Link
Journal: Blood Advances
Blood Adv (2018) 2 (2): 151–163.
https://doi.org/10.1182/bloodadvances.2017006668
Published: 2018
Includes: Supplemental data
Journal Articles

The human IL-15 superagonist ALT-803 directs SIV-specific CD8 + T cells into B-cell follicles

Gabriela M. Webb, Shengbin Li, Gwantwa Mwakalundwa, Joy M. Folkvord, Justin M. Greene, Jason S. Reed, Jeffery J. Stanton, Alfred W. Legasse, Theodore Hobbs, Lauren D. Martin, Byung S. Park, James B. Whitney, Emily K. Jeng, Hing C. Wong, Douglas F. Nixon, R. Brad Jones, Elizabeth Connick, Pamela J. Skinner, Jonah B. Sacha
Journal: Blood Advances
Blood Adv (2018) 2 (2): 76–84.
https://doi.org/10.1182/bloodadvances.2017012971
Published: 2018
Includes: Supplemental data
Journal Articles

Innate transcriptional effects by adjuvants on the magnitude, quality, and durability of HIV envelope responses in NHPs

Joseph R. Francica, Daniel E. Zak, Caitlyn Linde, Emilio Siena, Carrie Johnson, Michal Juraska, Nicole L. Yates, Bronwyn Gunn, Ennio De Gregorio, Barbara J. Flynn, Nicholas M. Valiante, Padma Malyala, Susan W. Barnett, Pampi Sarkar, Manmohan Singh, Siddhartha Jain, Margaret Ackerman, Munir Alam, Guido Ferrari, Andres Salazar, Georgia D. Tomaras, Derek T. O’Hagan, Alan Aderem, Galit Alter, Robert A. Seder
Journal: Blood Advances
Blood Adv (2017) 1 (25): 2329–2342.
https://doi.org/10.1182/bloodadvances.2017011411
Published: 2017
Includes: Supplemental data
Journal Articles

CD86 regulates myeloma cell survival

Catherine M. Gavile, Benjamin G. Barwick, Scott Newman, Paola Neri, Ajay K. Nooka, Sagar Lonial, Kelvin P. Lee, Lawrence H. Boise
Journal: Blood Advances
Blood Adv (2017) 1 (25): 2307–2319.
https://doi.org/10.1182/bloodadvances.2017011601
Published: 2017
Includes: Supplemental data
Journal Articles

A phase 2 study of panobinostat with lenalidomide and weekly dexamethasone in myeloma

Clinical Trials & Observations
Ajai Chari, Hearn J. Cho, Amishi Dhadwal, Gillian Morgan, Lisa La, Katarzyna Zarychta, Donna Catamero, Erika Florendo, Nadege Stevens, Daniel Verina, Elaine Chan, Violetta Leshchenko, Alessandro Laganà, Deepak Perumal, Anna Huo-Chang Mei, Kaity Tung, Jami Fukui, Sundar Jagannath, Samir Parekh
Journal: Blood Advances
Blood Adv (2017) 1 (19): 1575–1583.
https://doi.org/10.1182/bloodadvances.2017007427
Published: 2017
Includes: Supplemental data
Journal Articles

Accurate, simple, and inexpensive assays to diagnose F8 gene inversion mutations in hemophilia A patients and carriers

Debargh Dutta, Devi Gunasekera, Margaret V. Ragni, Kathleen P. Pratt
Journal: Blood Advances
Blood Adv (2016) 1 (3): 231–239.
https://doi.org/10.1182/bloodadvances.2016001651
Published: 2016