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Journal Articles

Molecular and cellular features of CTLA-4 blockade for relapsed myeloid malignancies after transplantation

Clinical Trials & Observations Brief Report
Livius Penter, Yi Zhang, Alexandra Savell, Teddy Huang, Nicoletta Cieri, Emily M. Thrash, Seunghee Kim-Schulze, Aashna Jhaveri, Jingxin Fu, Srinika Ranasinghe, Shuqiang Li, Wandi Zhang, Emma S. Hathaway, Matthew Nazzaro, Haesook T. Kim, Helen Chen, Magdalena Thurin, Scott J. Rodig, Mariano Severgnini, Carrie Cibulskis, Stacey Gabriel, Kenneth J. Livak, Corey Cutler, Joseph H. Antin, Sarah Nikiforow, John Koreth, Vincent T. Ho, Philippe Armand, Jerome Ritz, Howard Streicher, Donna Neuberg, F. Stephen Hodi, Sacha Gnjatic, Robert J. Soiffer, X. Shirley Liu, Matthew S. Davids, Pavan Bachireddy, Catherine J. Wu
Journal: Blood
Blood (2021) 137 (23): 3212–3217.
https://doi.org/10.1182/blood.2021010867
Published: 2021
Includes: Supplemental data
Journal Articles

T-cell activation profiles distinguish hemophagocytic lymphohistiocytosis and early sepsis

Vandana Chaturvedi, Rebecca A. Marsh, Adi Zoref-Lorenz, Erika Owsley, Vijaya Chaturvedi, Trung C. Nguyen, Jordana R. Goldman, Michael M. Henry, Jay N. Greenberg, Stephan Ladisch, Michelle L. Hermiston, Michael Jeng, Ahmed Naqvi, Carl E. Allen, Hector R. Wong, Michael B. Jordan
Journal: Blood
Blood (2021) 137 (17): 2337–2346.
https://doi.org/10.1182/blood.2020009499
Published: 2021
Includes: Supplemental data
Journal Articles

A T-cell–redirecting bispecific G-protein–coupled receptor class 5 member D x CD3 antibody to treat multiple myeloma

Kodandaram Pillarisetti, Suzanne Edavettal, Mark Mendonça, Yingzhe Li, Mark Tornetta, Alexander Babich, Nate Majewski, Matt Husovsky, Dara Reeves, Eileen Walsh, Diana Chin, Leopoldo Luistro, Jocelin Joseph, Gerald Chu, Kathryn Packman, Shoba Shetty, Yusri Elsayed, Ricardo Attar, François Gaudet
Journal: Blood
Blood (2020) 135 (15): 1232–1243.
https://doi.org/10.1182/blood.2019003342
Published: 2020
Includes: Supplemental data
Journal Articles

Supercharging your CAR

Sneha Ramakrishna, Kara L. Davis
Journal: Blood
Blood (2020) 135 (9): 593–594.
https://doi.org/10.1182/blood.2019004469
Published: 2020
Journal Articles

Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease

Govindarajan Thangavelu, Jing Du, Katelyn G. Paz, Michael Loschi, Michael C. Zaiken, Ryan Flynn, Patricia A. Taylor, Andrew Kemal Kirchmeier, Angela Panoskaltsis-Mortari, Leo Luznik, Kelli P. MacDonald, Geoffrey R. Hill, Ivan Maillard, David H. Munn, Jonathan S. Serody, William J. Murphy, David Miklos, Corey S. Cutler, John Koreth, Joseph H. Antin, Robert J. Soiffer, Jerome Ritz, Carol Dahlberg, Andrew T. Miller, Bruce R. Blazar
Journal: Blood
Blood (2020) 135 (1): 28–40.
https://doi.org/10.1182/blood.2019000032
Published: 2020
Includes: Supplemental data
Journal Articles

Blinatumomab-Induced T Cell Activation at Single Cell Transcriptome Resolution

Hong Yin, MD PhD, Yi Huo, PhD, Zhen Sheng, PhD, Chi-Ming Li, PhD, Daniel C Ellwanger, PhD, Daniel Lu, PhD, Oliver Homann, PhD, Songli Wang, MD PhD, Ruibao Ren, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3886.
https://doi.org/10.1182/blood-2019-124636
Published: 2019
Journal Articles

Mesothelin Targeting Bites for Pediatric AML: In Vivo Efficacy and Specificity

Anilkumar Gopalakrishnapillai, PhD, Colin Correnti, PhD, Anne Kisielewski, BS, Allison Kaeding, MD, Soheil Meshinchi, MD PhD, E. Anders Kolb, MD, Sonali Barwe, PhD MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 3925.
https://doi.org/10.1182/blood-2019-130941
Published: 2019
Journal Articles

Population Pharmacokinetics and Novel Exposure-Response Analyses to Inform Optimal Biologic Dose Selection for CD20-TCB, a T-Cell-Engaging Bispecific Antibody, in Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Nassim Djebli, PhD PharmD, Felix Jaminion, MSc, Johann Laurent, MSc, Francois Mercier, PhD, Nicole A Kratochwil, PhD, Ann-Marie E Bröske, PhD, Natalie Dimier, PhD, Cristiano Ferlini, MD, Tom Moore, MBChB, Martin Weisser, MD, Peter N Morcos, PharmD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3799.
https://doi.org/10.1182/blood-2019-123712
Published: 2019
Journal Articles

VISTA Is a Novel Regulator of Macrophage Biology

Parth Shah, MD, Mohamed Eltanbouly, BSc, Nicole Smits, Aurelien Sarde, Randolph Noelle, Rodwell Mabaera, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2320.
https://doi.org/10.1182/blood-2019-131310
Published: 2019
Journal Articles

Cold Plasma with Immunomodulatory Properties Has Significant Anti-Lymphoma Activities in Vitro and In Vivo

Fengdong Cheng, MD, Dayun Yan, PhD, Jie Chen, PhD, Michael Keidar, PhD, Eduardo Sotomayor, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5307.
https://doi.org/10.1182/blood-2019-131065
Published: 2019
Journal Articles

A Novel Revcar Platform for Switchable and Gated Tumor Targeting

Anja Feldmann, PhD, Anja Hoffmann, Enrico Kittel-Boselli, Ralf Bergmann, PhD, Stefanie Koristka, PhD, Nicole Berndt, PhD, Claudia Arndt, PhD, Liliana Raquel Loureiro, PhD, Nicola Mitwasi, Justyna Jureczek, Martin Bornhaeuser, MD, Michael Bachmann, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5611.
https://doi.org/10.1182/blood-2019-128436
Published: 2019
Journal Articles

Development of Novel Anti-CD10 Target Modules for Redirection of Universal CAR T Cells Against CD10-Positive Malignancies

Anja Feldmann, PhD, Stefanie Koristka, PhD, Claudia Arndt, PhD, Liliana Raquel Loureiro, PhD, Ralf Bergmann, PhD, Nicole Berndt, PhD, Anja Hoffmann, Justyna Jureczek, Nicola Mitwasi, Martin Bornhaeuser, MD, Václav Hořejší, Michael Bachmann, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5612.
https://doi.org/10.1182/blood-2019-128193
Published: 2019
Journal Articles

Itolizumab As a Potential Therapeutic for the Prevention and Treatment of Graft Vs Host Disease

Cherie Tracy Ng, PhD MPH, Jeanette Ampudia, BSc, Robert J. Soiffer, MD, Jerome Ritz, MD, Stephen Connelly, PhD MBA
Journal: Blood
Blood (2019) 134 (Supplement_1): 5603.
https://doi.org/10.1182/blood-2019-122787
Published: 2019
Journal Articles

Eomes and IL-10 Regulate Anti-Tumor Activity of T Cells in Chronic Lymphocytic Leukemia

Laura Llaó Cid, M.Sc, Philipp M Rößner, MD, Ekaterina Lupar, PhD, Bola S Hanna, PhD, Jérôme Paggetti, PhD, Etienne Moussay, PhD, Dolors Colomer, PhD, Sascha Dietrich, MD, Stephan Stilgenbauer, MD, Ana Izcue, PhD, Martina Seiffert, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4288.
https://doi.org/10.1182/blood-2019-128465
Published: 2019
Journal Articles

Investigation of Cell-Contact Dependent Alterations in Immune Synapse Formation between T Cells and BCP-ALL Cells

Britta Wenske, PhD, Lothar Marischen, PhD, Julia Welzenbach, André Heimbach, PhD, Per Hoffmann, PhD, Selim Corbacioglu, MD, David A Williams, MD, Anja Troeger, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2754.
https://doi.org/10.1182/blood-2019-128835
Published: 2019
Journal Articles

A Phase 1 Study of Flotetuzumab, a CD123 x CD3 DART ® Protein, Combined with MGA012, an Anti-PD-1 Antibody, in Patients with Relapsed or Refractory Acute Myeloid Leukemia

Andrew H. Wei, PhD FRACP, FRCPA, MBBS, Chun Yew Fong, MBBS,PhDFRACP,FRCPA, Pau Montesinos, MD PhD, Maria Calbacho, MD, Jordi Sierra Gil, MD PhD, Jaime Perez De Oteyza, MD PhD, Jacob M. Rowe, MB, BS, Ofir Wolach, MD, Yishai Ofran, MD, Yakir Moshe, MD, Jichao Sun, PhD, Jan Baughman, MPH, Eileen McNulty, MS, Ezio Bonvini, MD, Jon M. Wigginton, MD, Jan K Davidson-Moncada, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2662.
https://doi.org/10.1182/blood-2019-125966
Published: 2019
Journal Articles

The Role of Protein Tyrosine Phosphatase PTP4A3 in T-Cell Acute Lymphoblastic Leukemia Progression

Min Wei, MSc, Jessica Blackburn, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2539.
https://doi.org/10.1182/blood-2019-126256
Published: 2019
Journal Articles

Phase 1 Results of CNCT19: CD19 CAR Constructed of a New Anti-CD19 Chimeric Antigen Receptor in Relapsed or Refractory Acute Lymphoblastic Leukemia

Runxia Gu, Fang Liu, Dehui Zou, MD, Bingcheng Liu, Wei Liu, Xiaojuan Chen, MD, Kaiqi Liu, Ye Guo, MD, Xiaoyuan Gong, Rui Lv, Xia Chen, Chunlin Zhou, Mengjun Zhong, Yingxi Xu, Huijun Wang, Hui Wei, MD, Yingchang Mi, MD, Lugui Qiu, MD PhD, Lulu Lv, Min Wang, MD, Ying Wang, MD, Xiaofan Zhu, MD, Jianxiang Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2622.
https://doi.org/10.1182/blood-2019-125342
Published: 2019
Journal Articles

CD3xCD19 Dart Treatment Is Efficient in Venetoclax Resistant CLL and Reverses T Cell Dysfunction

Anne W. J. Martens, MSc, Susanne R. Janssen, MSc, Ingrid A.M. Derks, Sanne Tonino, MD PhD, Eric Eldering, Gerritje J. W. van der Windt, Arnon P. Kater, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3043.
https://doi.org/10.1182/blood-2019-123350
Published: 2019
Journal Articles

Redirecting T-Cells Against AML in a Multidimensional Targeting Space Using T-Cell Engaging Antibody Circuits (TEAC)

Eleanor Minogue, BSc, David Millar, PhD, Yan Chuan, PhD, Songfa Zhang, MD PhD, Korneel Grauwet, PhD, Mei Guo, Adam Langenbucher, Cyril H Benes, James Heather, PhD, Jeremy Minshull, PhD, Michael S. Lawrence, PhD, Rupa Narayan, David M. Langenau, PhD, Timothy A. Graubert, MD, Mark Cobbold
Journal: Blood
Blood (2019) 134 (Supplement_1): 2653.
https://doi.org/10.1182/blood-2019-127634
Published: 2019