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Journal Articles

PRMT5 Inhibition Modulates E2F1 Methylation and Gene Regulatory Networks Leading to Therapeutic Efficacy in JAK2VF Mutant MPN

Blood (2019) 134 (Supplement_1): 473.

https://doi.org/10.1182/blood-2019-127122

Published: 2019

Journal Articles

Phase I Study of Cord Blood Transplantation with Intra-Bone Marrow Injection of Mesenchymal Stem Cells

Tatsunori Goto, MD, Makoto Murata, MD PhD, Tetsuya Nishida, MD PhD, Seitaro Terakura, MD PhD, Sonoko Kamoshita, MD, Yuichi Ishikawa, MD PhD, Yoko Ushijima, MD PhD, Yoshiya Adachi, MD PhD, Katsuyoshi Kato, PhD, Akihiro Hirakawa, PhD, Satoshi Nishiwaki, MD PhD, Nobuhiro Nishio, MD PhD, Yoshiyuki Takahashi, MD PhD, Yoshihisa Kodera, MD, Tadashi Matsushita, Hitoshi Kiyoi, MD PhD

Blood (2019) 134 (Supplement_1): 2004.

https://doi.org/10.1182/blood-2019-122101

Published: 2019

Journal Articles

CRISPR-Cas9 Genome Editing of γ-Globin Promoters in Human Hematopoietic Stem Cells to Induce Erythrocyte Fetal Hemoglobin for Treatment of β-Hemoglobinopathies

Blood (2019) 134 (Supplement_1): 2066.

https://doi.org/10.1182/blood-2019-131318

Published: 2019

Journal Articles

Proof of Concept for Repair of Sickle Cell Disease By Non-Myeloablative MHC Disparate T Cell Depleted HSCT Combined with Donor-Derived Veto Cells

Aloukick Kumar Singh, PhD, Elias Schetzen, PhD, Esther BACHAR Lustig, PhD, Wei-Hsin Liu, M.Sc, Raj Kumar Yadav, PhD, Sandeep Kumar Yadav, PhD, Kathryn McGinnis, M.Sc, Yair Reisner, PhD

Blood (2019) 134 (Supplement_1): 1919.

https://doi.org/10.1182/blood-2019-124594

Published: 2019

Journal Articles

Rate of Sickle Hemoglobin Recovery in Sickle Cell Disease Patients Undergoing Red Blood Cell (RBC) Exchange Transfusion Is Associated with Age of Patients and Number of RBC Units Transfused

John Chinawaeze Aneke, MBBS, Aliraza Rajabali, Nafanta Fadiga, Stéphanie Forté, MD MSc, FRCPC, George A. Tomlinson, PhD BSc, MSc, Christine M. Cserti-Gazdewich, BSc, MD FRCPC, Christopher J. Patriquin, MDFRCPC,MSc, Richard Ward, MSc, MRCP, FRCPath, Jacob Pendergrast, MDFRCPC, David Barth, MD FRCPC, Kevin H. M. Kuo, MDMSc,FRCPC

Blood (2019) 134 (Supplement_1): 2170.

https://doi.org/10.1182/blood-2019-122072

Published: 2019

Journal Articles

ATG4A is a Novel Regulator of Mitophagy during Human Erythropoiesis

Massiel Chavez Stolla, PhD, Neele Thom, B.S., Andreea Reilly, Courtnee Clough, Janis L. Abkowitz, MD, Sergei Doulatov, PhD

Blood (2019) 134 (Supplement_1): 3522.

https://doi.org/10.1182/blood-2019-130567

Published: 2019

Journal Articles

Hematological Changes in Chronic Sustained Hypoxia and Chronic Intermittent Hypoxia in a Mouse Model

Jihyun Song, PhD, Krishna M Sundar, MD, John Hoidal, MD, Josef T. Prchal, MD

Blood (2019) 134 (Supplement_1): 3525.

https://doi.org/10.1182/blood-2019-131309

Published: 2019

Journal Articles

Disbalanced Erythroid Ferroportin Expression Contributes to Ineffective Erythroid Output in Anemia of Chronic Disease

Verena Petzer, MD, Piotr Tymoszuk, PhD, Markus Seifert, Natascha Brigo, MSc, Philipp Grubwieser, Sylvia Berger, Richard Hilbe, Egon Demetz, PhD, Lara Valente de Souza, MD, Günter Weiss, Univ. Prof. Dr., Dominik Wolf, Univ. Prof. Dr., Igor Theurl, MD PhD

Blood (2019) 134 (Supplement_1): 3533.

https://doi.org/10.1182/blood-2019-131202

Published: 2019

Journal Articles

Abnormal Cytokine Production By Mast Cell Cultures from Sickle Cell Anemia Patients in Response to Inflammatory Stimuli and to Co-Culture with Eosinophils

Myriam Salazar-Terreros, PhDMSc, Kleber Yotsumoto Fertrin, MD PhD, Nicolas Moreno Reyes, PhD, Fernando Ferreira Costa, MD PhD, Carla F. Franco-Penteado, BSc, PhD

Blood (2019) 134 (Supplement_1): 3566.

https://doi.org/10.1182/blood-2019-129509

Published: 2019

Journal Articles

CELL-Derived Microparticles and Sickle CELL Disease Chronic Vasculopathy in Sub-Saharan Africa

Abdoul Karim Dembele, MD, Claudine Lapoumeroulie, PhD, Mor Diaw, PhD, Oumar Tessougué, MD, Lucile Offredo, MS, Dapa Aly Diallo, MD, Saliou Diop, MD MSc, Jacques Elion, MD PhD, Yves Colin Aronovicz, Pierre Louis Tharaux, MD PhD, Xavier Jouven, MD PhD, Marc Romana, PhD, Brigitte Ranque, MD PhD, Caroline Le Van Kim, PhD

Blood (2019) 134 (Supplement_1): 3568.

https://doi.org/10.1182/blood-2019-121334

Published: 2019

Journal Articles

Regulation of Iron Homeostasis By PTG-300 Improves Disease Parameters in Mouse Models for Beta-Thalassemia and Hereditary Hemochromatosis

Roopa Taranath, PhD, Gregory Bourne, PhD, Li Zhao, MD PhD, Brian Frederick, MS, Chelsea King, BA, David Liu, PhD

Blood (2019) 134 (Supplement_1): 3540.

https://doi.org/10.1182/blood-2019-129309

Published: 2019

Journal Articles

Normal Hemoglobin Concentrations in Obstructive Sleep Apnea and Associated Neocytolysis-Mediated Hemolysis and Inflammation Mediated Suppression of Expected Elevated Hemoglobin

Jihyun Song, PhD, Krishna M Sundar, MD, Monika Horvathova, MSc, PhD, Tsewang Tashi, MD, Carsten Lundby, PhD, Tomas Ganz, MD PhD, Josef T. Prchal, MD

Blood (2019) 134 (Supplement_1): 3507.

https://doi.org/10.1182/blood-2019-131269

Published: 2019

Journal Articles

Long-Term Safety and Efficacy of Mitapivat (AG-348), a Pyruvate Kinase Activator, in Patients with Pyruvate Kinase Deficiency: The DRIVE PK Study

Rachael F. Grace, MD, D. Mark Layton, MB BS, FRCP, FRCPCH, Frédéric Galactéros, MD PhD, Wilma Barcellini, MD, Eduard J. van Beers, MD PhD, Hassan M. Yaish, MD, Yaddanapudi Ravindranath, MBBS, Kevin H. M. Kuo, MDMSc,FRCPC, Sujit Sheth, MD, Janet L. Kwiatkowski, MD MSCE, Lei Hua, PhD, Peter F. Hawkins, PhD, Chris Mix, MD, Bertil Glader, MD PhD

Blood (2019) 134 (Supplement_1): 3512.

https://doi.org/10.1182/blood-2019-123406

Published: 2019

Journal Articles

A Phase 2 Open-Label Study of Danicopan (ACH-0144471) in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have an Inadequate Response to Eculizumab Monotherapy

Austin Kulasekararaj, MBBS MDMRCP FRCPath, Antonio M. Risitano, MD PhD, Jaroslaw P. Maciejewski, MD PhD, Rosario Notaro, MD, Peter Browett, BMedSci, MBChB, FRACP, FRCPA, Jong-Wook Lee, MD, Mingjun Huang, PhD, Michael Geffner, MD, Robert A. Brodsky, MD

Blood (2019) 134 (Supplement_1): 3514.

https://doi.org/10.1182/blood-2019-124748

Published: 2019

Journal Articles

Predictors of Response to Erythropoietin in Autoimmune Hemolytic Anemia

Bruno Fattizzo, MD, Marc Michel, Laetitia Languille, Juri Giannotta, MD, Henrik Frederiksen, MD Prof, Francesca Romana Mauro, MD, Bernd Jilma, Elisa Lucchini, MD, Andrea Patriarca, MD, Francesco Zaja, MD, Anita Hill, MD PhD, Sigbjorn Berentsen, MD PhD, Wilma Barcellini

Blood (2019) 134 (Supplement_1): 3516.

https://doi.org/10.1182/blood-2019-125524

Published: 2019

Journal Articles

Deciphering the Causal Diagnosis of Hydrops Fetalis or Unexplained Fetal Anemia Using Targeted Next Generation and Exome Sequencing

Julie Galimand, Helene Bourdeau, Odile Fenneteau, Sophie Dreux, Nathalie Couque, PharmD, Severine Drunat, PharmD, PhD, Serge Pissard, PhD, Thierry Leblanc, MD, Anne Lambilliotte, MD, Catherine Thong Vanh, Caroline Alby, jelena-Hélène martinovic-Bouriel, Chloé Quelin, Mohandas Narla, DSc, Anne Cortey, Lydie Da Costa

Blood (2019) 134 (Supplement_1): 3519.

https://doi.org/10.1182/blood-2019-127432

Published: 2019

Journal Articles

Effects of Targeting the Interleukin-1 Receptor in a Murine Model of Sickle Cell Disease

Jessica Venugopal, PhD, Jintao Wang, PhD, Chiao Guo, Daniel Eitzman, MD

Blood (2019) 134 (Supplement_1): 2259.

https://doi.org/10.1182/blood-2019-128980

Published: 2019

Journal Articles

Improvement in Red Blood Cell Physiology in Children with Sickle Cell Anemia Receiving Voxelotor

Satheesh Chonat, MD, Earl Fields, Hannah Baratz, Amanda Watt, Mira Pochron, PhD, Sandy Dixon, Margaret Tonda, PharmD, Joshua Lehrer-Graiwer, MD MPhil, FACC, Clark Brown, MD PhD, David R. Archer, PhD

Blood (2019) 134 (Supplement_1): 2281.

https://doi.org/10.1182/blood-2019-129351

Published: 2019

Journal Articles

Hypoxia Dependent and Independent Dysregulation of the Transcriptome in Sickle Cell Anemia

Xu Zhang, PhD, Jihyun Song, PhD, Binal N. Shah, Taif Hassan, Galina Miasnikova, MD, Adelina Sergueeva, MD, Josef T. Prchal, MD, Victor R Gordeuk, MD

Blood (2019) 134 (Supplement_1): 2262.

https://doi.org/10.1182/blood-2019-132078

Published: 2019

Journal Articles

High Natural Killer Cell Count at Diagnosis Predicts a Good Response to Immunosuppressive Therapy in Aplastic Anemia

Atsushi Narita, Hideki Muramatsu, MD PhD, Yinyan Xu, Motoharu Hamada, MD PhD, Daisuke Ichikawa, MD, Eri Nishikawa, MD PhD, Nozomu Kawashima, MD, Yusuke Okuno, MD PhD, Nobuhiro Nishio, MD PhD, Hirohito Yamazaki, MD PhD, Shinji Nakao, MD PhD, Seiji Kojima, MD PhD, Yoshiyuki Takahashi, MD PhD

Blood (2019) 134 (Supplement_1): 2505.

https://doi.org/10.1182/blood-2019-124945

Published: 2019

NARROW

PRMT5 Inhibition Modulates E2F1 Methylation and Gene Regulatory Networks Leading to Therapeutic Efficacy in JAK2VF Mutant MPN

Phase I Study of Cord Blood Transplantation with Intra-Bone Marrow Injection of Mesenchymal Stem Cells

CRISPR-Cas9 Genome Editing of γ-Globin Promoters in Human Hematopoietic Stem Cells to Induce Erythrocyte Fetal Hemoglobin for Treatment of β-Hemoglobinopathies

Proof of Concept for Repair of Sickle Cell Disease By Non-Myeloablative MHC Disparate T Cell Depleted HSCT Combined with Donor-Derived Veto Cells

Rate of Sickle Hemoglobin Recovery in Sickle Cell Disease Patients Undergoing Red Blood Cell (RBC) Exchange Transfusion Is Associated with Age of Patients and Number of RBC Units Transfused

ATG4A is a Novel Regulator of Mitophagy during Human Erythropoiesis

Hematological Changes in Chronic Sustained Hypoxia and Chronic Intermittent Hypoxia in a Mouse Model

Disbalanced Erythroid Ferroportin Expression Contributes to Ineffective Erythroid Output in Anemia of Chronic Disease

Abnormal Cytokine Production By Mast Cell Cultures from Sickle Cell Anemia Patients in Response to Inflammatory Stimuli and to Co-Culture with Eosinophils

CELL-Derived Microparticles and Sickle CELL Disease Chronic Vasculopathy in Sub-Saharan Africa

Regulation of Iron Homeostasis By PTG-300 Improves Disease Parameters in Mouse Models for Beta-Thalassemia and Hereditary Hemochromatosis

Normal Hemoglobin Concentrations in Obstructive Sleep Apnea and Associated Neocytolysis-Mediated Hemolysis and Inflammation Mediated Suppression of Expected Elevated Hemoglobin

Long-Term Safety and Efficacy of Mitapivat (AG-348), a Pyruvate Kinase Activator, in Patients with Pyruvate Kinase Deficiency: The DRIVE PK Study

A Phase 2 Open-Label Study of Danicopan (ACH-0144471) in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have an Inadequate Response to Eculizumab Monotherapy

Predictors of Response to Erythropoietin in Autoimmune Hemolytic Anemia

Deciphering the Causal Diagnosis of Hydrops Fetalis or Unexplained Fetal Anemia Using Targeted Next Generation and Exome Sequencing

Effects of Targeting the Interleukin-1 Receptor in a Murine Model of Sickle Cell Disease

Improvement in Red Blood Cell Physiology in Children with Sickle Cell Anemia Receiving Voxelotor

Hypoxia Dependent and Independent Dysregulation of the Transcriptome in Sickle Cell Anemia

High Natural Killer Cell Count at Diagnosis Predicts a Good Response to Immunosuppressive Therapy in Aplastic Anemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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