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Journal Articles

The Inherited Platelet Disorder of RUNX1 Haploinsufficiency (Familial Platelet Disorder with Associated Myeloid Malignancy (FPDMM)) Has a Marked Deficiency of Megakaryocyte-Biased Hematopoietic Progenitor Cells: Mechanistic Studies and Drug Correction

Brian Estevez, PhD, Sara Borst, BS, Danuta Jadwiga Jarocha, PhD, Varun Sudunagunta, Michael Gonzalez, PhD, Peng Gao, Kai Tan, Deborah L French, PhD, Paul Gadue, PhD, Mortimer Poncz, MD

Blood (2019) 134 (Supplement_1): 220.

https://doi.org/10.1182/blood-2019-124851

Published: 2019

Journal Articles

Transcriptional and Spatial Heterogeneity of Mouse Megakaryocytes at Single-Cell Resolution

Shu Sun, BS, Chen Jin, PhD, Yueying Li, MD, Jia Si, Yueli Cui, Matthew T. Rondina, MD, Fuchou Tang, PhD, Qian-fei Wang, PhD

Blood (2019) 134 (Supplement_1): 275.

https://doi.org/10.1182/blood-2019-129471

Published: 2019

Journal Articles

Lung-Resident Megakaryocytes Display Distinct Transcriptional and Functional Properties

Anthony K Yeung, BS, Carlos Villacorta-Martin, MSc, Stephanie Hon, MD, Todd W Dowrey, BS, George J Murphy, PhD

Blood (2019) 134 (Supplement_1): 4999.

https://doi.org/10.1182/blood-2019-127200

Published: 2019

Journal Articles

Cross-Strain Platelet Immunization in Selected Mouse Strains Recapitulates Clinical and Serologic Findings Typical of Post-Transfusion Purpura (PTP)

Daniel W. Bougie, PhD, Jessica Sutton, Richard H. Aster, MD

Blood (2019) 134 (Supplement_1): 2349.

https://doi.org/10.1182/blood-2019-126815

Published: 2019

Journal Articles

Dose-Dependent Iron Chelating Effects of Eltrombopag on in Vitro Human Megakaryopoiesis

Zhi-Jian Liu, PhD, Emoke Deschmann, MD, Haley E. Ramsey, PhDMSc, Henry Feldman, Bethan Psaila, MD PhD, Nichola Cooper, MD MRCP, Evangelia Vlachodimtropoulou Koumoutsea, MBBS,PhDBSc, John B. Porter, MA MDFRCP FRCPath, James B. Bussel, MD, Michael Georgieff, MD, Martha Sola-Visner, MD

Blood (2019) 134 (Supplement_1): 2475.

https://doi.org/10.1182/blood-2019-131895

Published: 2019

Journal Articles

Altered Megakaryocytes Are Associated with Development of Pulmonary Fibrosis in Mice Carrying the Hypomorphic Gata1 low Mutation

Barbara Bacci, PhD, Francesca Gobbo, Mariana Roccaro, Angelo Peli, PhD, Maria Zingariello, PhD, Fabrizio Martelli, PhD, Paola Verachi, Claudio Bardelli, PhD, Maria Mazzarini, Giuseppe Sarli, PhD, Anna Rita Migliaccio, PhD

Blood (2019) 134 (Supplement_1): 2336.

https://doi.org/10.1182/blood-2019-123994

Published: 2019

Journal Articles

A Novel Platelet-Targeting Fibrinolytic Strategy: Endocytosed Urokinase By Megakaryocytes Is Stored in α-Granules and Is Functional In Vivo in a Murine Model of Thrombosis

Hyunsook Ahn, MSc, John Tkaczynski, BS, Khalil Bdeir, PhD, Victoria Stepanova, Douglas B. Cines, MD, Mortimer Poncz, MD, Sergei Zaitsev

Blood (2019) 134 (Supplement_1): 3627.

https://doi.org/10.1182/blood-2019-124501

Published: 2019

Journal Articles

Sialic Acid Content on Platelet Surface Glycoproteins Modulates Thrombin-Induced Activation

Alexander Prete, Alexander Urtula, Renata Grozovsky, PhD

Blood (2018) 132 (Supplement 1): 3730.

https://doi.org/10.1182/blood-2018-99-119303

Published: 2018

Journal Articles

A Novel Anti-Glycoprotein (GP) Iba-Targeting Chimeric Fibrinolytic Agent Demonstrates In Vivo Efficacy Against Human Platelet-Enriched Thrombi in Mice

Randolph Lyde, PhD, Hyunsook Ahn, Vincent Hayes, Sergei Zaistev, PhD, Shu-Wha Lin, PhD, Zaverio M. Ruggeri, MD, Renhao Li, PhD, Vladimir Muzykantov, Douglas B. Cines, MD, Mortimer Poncz, MD

Blood (2018) 132 (Supplement 1): 990.

https://doi.org/10.1182/blood-2018-99-115262

Published: 2018

Journal Articles

Role of Somatic Mutations and Clonal Thrombopoiesis in Immune Thrombocytopenia

Sami Ibrahimi, MD, James George, MD, Patrick M Gaffney, MD, Sara K. Vesely, PhD MPH, Adam S. Asch, MD

Blood (2018) 132 (Supplement 1): 130.

https://doi.org/10.1182/blood-2018-99-111413

Published: 2018

Journal Articles

Aberrant Expression of MicroRNAs in CD4 + Cells May Contribute to the Imbalance of Th17/Treg Cells in Primary Immune Thrombocytopenia

Mingqiang Hua, Qi Feng, Ju Li, Yu Hou, Shuwen Wang, Anli Liu, Jun Peng, MDPhD, Ming Hou, MDPhD

Blood (2018) 132 (Supplement 1): 1140.

https://doi.org/10.1182/blood-2018-99-115569

Published: 2018

Journal Articles

Platelets Promote Activation of the Complement System in Ovarian Cancer

Omayra Gonzalez Pagan, MD, Min Soon Cho, PhD, Vahid Afshar-Kharghan, MD

Blood (2018) 132 (Supplement 1): 4970.

https://doi.org/10.1182/blood-2018-99-116752

Published: 2018

Journal Articles

Antiplatelet Antibody Testing in Immune Thrombocytopenia and Evans Syndrome: Longitudinal Serologic Evolution and Relation to Clinical Features

Hanny Al-Samkari, MD, David J. Kuter, MD DPhil

Blood (2018) 132 (Supplement 1): 1137.

https://doi.org/10.1182/blood-2018-99-118403

Published: 2018

Journal Articles

Novel Antibodies Against Glycoprotein Ibα Inhibit Pulmonary Metastasis By Affecting Vwf-Gpibα Interaction

Qi Yingxue, Wenchun Chen, PhD, Ke Xu, Fengying Wu, Xuemei Fan, Shengxiang Ren, Junling Liu, Wei Deng, PhD, Jun Zhang, Renhao Li, PhD, Jianwen Liu, Xin Liang, PhD

Blood (2018) 132 (Supplement 1): 1133.

https://doi.org/10.1182/blood-2018-99-117613

Published: 2018

Journal Articles

14-3-3 proteins in platelet biology and glycoprotein Ib-IX signaling

Yunfeng Chen, Zaverio M. Ruggeri, Xiaoping Du

Blood (2018) 131 (22): 2436–2448.

https://doi.org/10.1182/blood-2017-09-742650

Published: 2018

Journal Articles

Mechanisms of platelet clearance and translation to improve platelet storage

M. Edward Quach, Wenchun Chen, Renhao Li

Blood (2018) 131 (14): 1512–1521.

https://doi.org/10.1182/blood-2017-08-743229

Published: 2018

Journal Articles

Fc-independent immune thrombocytopenia via mechanomolecular signaling in platelets

M. Edward Quach, Matthew A. Dragovich, Wenchun Chen, Anum K. Syed, Wenpeng Cao, Xin Liang, Wei Deng, Simon F. De Meyer, Guangheng Zhu, Jun Peng, Heyu Ni, Carolyn M. Bennett, Ming Hou, Jerry Ware, Hans Deckmyn, X. Frank Zhang, Renhao Li

Blood (2018) 131 (7): 787–796.

https://doi.org/10.1182/blood-2017-05-784975

Published: 2018

Includes: Supplemental data

Journal Articles

Multi-Phase Ex Vivo Generation of Platelet-like Particles from CD34 + Cord Blood Cell-Derived Megakaryocytes

Jia J. Wu, BS, Darryl A. Abbott, BS, Meryem K. Terzioglu, MD, Rajeev Ranjan, PhD, Dolores Mahmud, PhD, Hasan Issa, MBBch, Neda Bagheri, PhD, Nadim Mahmud, MBBS, PhD, William M. Miller, PhD

Blood (2017) 130 (Supplement 1): 3196.

https://doi.org/10.1182/blood.V130.Suppl_1.3196.3196

Published: 2017

Journal Articles

Sequestration Pattern in ITP Liver/Spleen Scan Correlates with the Presence of Anti-Glycoprotein V Antibodies in ITP Patients

Sufia N. Amini, MD, Annemieke Sobels, MSc, Christianne Duchateau, MD, Masja De Haas, MD PhD, Leendert Porcelijn, MD, Roger Schutgens, MD PhD, Jaap Jan Zwaginga, MD PhD, Martin R. Schipperus, MD PhD

Blood (2017) 130 (Supplement 1): 1046.

https://doi.org/10.1182/blood.V130.Suppl_1.1046.1046

Published: 2017

Journal Articles

High-Throughput Sequencing of IgG B-Cell Receptors Reveals the Frequent Usage of the Rearranged IGHV4-28//IGHJ4 Gene in Primary Immune Thrombocytopenia in Adults

Naohito Fujishima, MD, Masaru Togashi, MD PhD, Ryo Hasegawa, MD, Ken Watanabe, MD, Akiko Saga, MD PhD, Ayumi Omokawa, MD PhD, Tomoo Saga, MD PhD, Shigeharu Ueki, MD PhD, Naoto Takahashi, Kazutaka Kitaura, DVM, PhD, Ryuji Suzuki, DVM, PhD, Makoto Hirokawa, MD PhD

Blood (2017) 130 (Supplement 1): 3582.

https://doi.org/10.1182/blood.V130.Suppl_1.3582.3582

Published: 2017

NARROW

The Inherited Platelet Disorder of RUNX1 Haploinsufficiency (Familial Platelet Disorder with Associated Myeloid Malignancy (FPDMM)) Has a Marked Deficiency of Megakaryocyte-Biased Hematopoietic Progenitor Cells: Mechanistic Studies and Drug Correction

Transcriptional and Spatial Heterogeneity of Mouse Megakaryocytes at Single-Cell Resolution

Lung-Resident Megakaryocytes Display Distinct Transcriptional and Functional Properties

Cross-Strain Platelet Immunization in Selected Mouse Strains Recapitulates Clinical and Serologic Findings Typical of Post-Transfusion Purpura (PTP)

Dose-Dependent Iron Chelating Effects of Eltrombopag on in Vitro Human Megakaryopoiesis

Altered Megakaryocytes Are Associated with Development of Pulmonary Fibrosis in Mice Carrying the Hypomorphic Gata1 low Mutation

A Novel Platelet-Targeting Fibrinolytic Strategy: Endocytosed Urokinase By Megakaryocytes Is Stored in α-Granules and Is Functional In Vivo in a Murine Model of Thrombosis

Sialic Acid Content on Platelet Surface Glycoproteins Modulates Thrombin-Induced Activation

A Novel Anti-Glycoprotein (GP) Iba-Targeting Chimeric Fibrinolytic Agent Demonstrates In Vivo Efficacy Against Human Platelet-Enriched Thrombi in Mice

Role of Somatic Mutations and Clonal Thrombopoiesis in Immune Thrombocytopenia

Aberrant Expression of MicroRNAs in CD4 + Cells May Contribute to the Imbalance of Th17/Treg Cells in Primary Immune Thrombocytopenia

Platelets Promote Activation of the Complement System in Ovarian Cancer

Antiplatelet Antibody Testing in Immune Thrombocytopenia and Evans Syndrome: Longitudinal Serologic Evolution and Relation to Clinical Features

Novel Antibodies Against Glycoprotein Ibα Inhibit Pulmonary Metastasis By Affecting Vwf-Gpibα Interaction

14-3-3 proteins in platelet biology and glycoprotein Ib-IX signaling

Mechanisms of platelet clearance and translation to improve platelet storage

Fc-independent immune thrombocytopenia via mechanomolecular signaling in platelets

Multi-Phase Ex Vivo Generation of Platelet-like Particles from CD34 + Cord Blood Cell-Derived Megakaryocytes

Sequestration Pattern in ITP Liver/Spleen Scan Correlates with the Presence of Anti-Glycoprotein V Antibodies in ITP Patients

High-Throughput Sequencing of IgG B-Cell Receptors Reveals the Frequent Usage of the Rearranged IGHV4-28//IGHJ4 Gene in Primary Immune Thrombocytopenia in Adults

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American Society of Hematology

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American Society of Hematology

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