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Journal Articles

Loss of Dnmt3a Dysregulates Hematopoietic Homeostasis and Myeloid Skewing Via the PI3Kinase Pathway: PI3Kα/β Inhibition Corrects Extramedullary Hematopoiesis and Myeloid Skewing Due to Loss of Dnmt3a

Lakshmi Reddy Palam, PhD, Baskar Ramdas, PhD, Katelyn Pickerell, Reuben Kapur, PhD

Blood (2019) 134 (Supplement_1): 723.

https://doi.org/10.1182/blood-2019-131036

Published: 2019

Journal Articles

Temporal and Spatially Regulated Oncogenic KIT Expression and Loss of Dnmt3a Cooperate to Drive MPN Development: Role of PI3Kinase in Dnmt3a Loss Induced Hyperproliferation in Myeloid Cells

Lakshmi Reddy Palam, PhD, Baskar Ramdas, PhD, Sridhar reddy Srivatsan, MS, Sarath Chandra Janga, PhD, Axel Roers, PhD, Alexander Gerbaulet, Reuben Kapur, PhD

Blood (2018) 132 (Supplement 1): 3055.

https://doi.org/10.1182/blood-2018-99-118721

Published: 2018

Journal Articles

Integrated Analysis of Global DNA Methylation and Transcription Reveals a Leukemia Subtype with Extreme Hypermethylation Associated with Silencing of Regulators of Differentiation

Claudia Gebhard, PhD, Roger Mulet-Lazaro, B.Sc., Lucia Schwarzfischer, Dagmar Glatz, Margit Nuetzel, Daniel Heudobler, MD, Sandra Pohl, Wolfgang Herr, MD, Gerhard Ehninger, MD, Claudia Erpelinck-Verschueren, B.Sc., Stanley van Herk, B.Sc., B.J. Wouters, Christian Thiede, MD, Ruud Delwel, PhD, Michael Rehli, PhD

Blood (2018) 132 (Supplement 1): 2608.

https://doi.org/10.1182/blood-2018-99-118521

Published: 2018

Journal Articles

tfec controls the hematopoietic stem cell vascular niche during zebrafish embryogenesis

Christopher B. Mahony, Richard J. Fish, Corentin Pasche, Julien Y. Bertrand

Blood (2016) 128 (10): 1336–1345.

https://doi.org/10.1182/blood-2016-04-710137

Published: 2016

Includes: Multimedia, Supplemental data

Journal Articles

Genomic-Wide Analysis By High Resolution SNP Array Identifies Novel Genomic Alteration in Acute Myeloid Leukemia

Blood (2015) 126 (23): 2600.

https://doi.org/10.1182/blood.V126.23.2600.2600

Published: 2015

Journal Articles

CD26 Is a Novel Target for the Treatment of Tumor Progression and Its Related Osteolytic Bone Disease in Multiple Myeloma

Hiroko Nishida, MD, PhD, Hiroko Madokoro, Hiroshi Suzuki, Mutsumi Hayashi, MD, PhD, Chikao Morimoto, MD, PhD, Michiie Sakamoto, MD, PhD, Taketo Yamada, MD, PhD

Blood (2015) 126 (23): 1809.

https://doi.org/10.1182/blood.V126.23.1809.1809

Published: 2015

Journal Articles

Novel Functional Roles for Ten-Eleven-Translocation 2 (Tet2) in Normal and Leukemic Growth of Mast Cells

Raghuveer Mali, PhD, Holly Rene Martin, PhD, Baskar Ramdas, PhD, Lakshmi Palam, PhD, Valeria Visconte, PhD, Tiu Ramon, MD, Helmut Hanenberg, MD, Mingjiang Xu, MD PhD, Reuben Kapur, PhD

Blood (2015) 126 (23): 775.

https://doi.org/10.1182/blood.V126.23.775.775

Published: 2015

Journal Articles

BCR-ABL Tyrosine Kinase Inhibitors Interfere with the PI3K/Akt Signalling Pathway and Activate the Microphthalmia-Associated Transcription Factor (MITF) in Human Dendritic Cells

Daniela Doerfel, MD, Michael Gutknecht, Melanie Märklin, Lothar Kanz, MD, Helmut R. Salih, MD, Frank Gruenebach, Martin R Müller, MD PhD, Susanne M Rittig, MD

Blood (2014) 124 (21): 1416.

https://doi.org/10.1182/blood.V124.21.1416.1416

Published: 2014

Journal Articles

Humanized Anti-CD26 Monoclonal Antibody Inhibits Osteoclast Bone Resorption Activity Via Blockade Of P38MAPK Signaling In Multiple Myeloma

Hiroko Nishida, M.D., Ph.D., Hiroko Madokoro, Hiroshi Suzuki, Michiie Sakamoto, M.D., Ph.D., Chikao Morimoto, M.D., Ph.D., Taketo Yamada, M.D., Ph.D

Blood (2013) 122 (21): 1918.

https://doi.org/10.1182/blood.V122.21.1918.1918

Published: 2013

Journal Articles

Ikaros limits basophil development by suppressing C/EBP-α expression

Kavitha N. Rao, Craig Smuda, Gregory D. Gregory, Booki Min, Melissa A. Brown

Blood (2013) 122 (15): 2572–2581.

https://doi.org/10.1182/blood-2013-04-494625

Published: 2013

Includes: Supplemental data

Journal Articles

A novel role of BMP4 in adult hematopoietic stem and progenitor cell homing via Smad independent regulation of integrin-α4 expression

Satish Khurana, Shannon Buckley, Sarah Schouteden, Stephen Ekker, Anna Petryk, Michel Delforge, An Zwijsen, Catherine M. Verfaillie

Blood (2013) 121 (5): 781–790.

https://doi.org/10.1182/blood-2012-07-446443

Published: 2013

Includes: Supplemental data

Journal Articles

Targeting CD26 with Humanized Monoclonal Antibody, As a Novel Approach to Inhibit Human Osteoclast Differentiation and Subsequent Bone Resorption

Hiroko Nishida, MD., PhD., Hiroko Madokoro, Hiroshi Suzuki, Michiie Sakamoto, M.D., Ph.D., Chikao Morimoto, M.D., Ph.D., Taketo Yamada, MD, PhD

Blood (2012) 120 (21): 1348.

https://doi.org/10.1182/blood.V120.21.1348.1348

Published: 2012

Journal Articles

Molecular Characterization of the Leukemic Niche in Chronic Myeloid Leukemia (CML) and Evaluation of a Leukemia / Niche Cross-Talk

Djamel Aggoune, Nathalie Sorel, PhD, Sanaa El Marsafy, MD, PhD, Marie Laure Bonnet, Denis Clay, Marie Claude Meunier, Karin Tarte, Olivier Herault, MD, PhD, Jorge Domenech, MD, PhD, Agnès Guerci, MD, Jean-Claude Chomel, PharmD, PhD, Ali G Turhan, M.D., PhD

Blood (2012) 120 (21): 908.

https://doi.org/10.1182/blood.V120.21.908.908

Published: 2012

Journal Articles

A Novel Osteoclastic Network Determines In Vitro Niche for Mouse and Human Hematopoietic Stem Cells

Eric Deneault, PhD, Brian T Wilhelm, PhD, Frederic Barabe, MD, Guy Sauvageau, MD, PhD

Blood (2011) 118 (21): 1325.

https://doi.org/10.1182/blood.V118.21.1325.1325

Published: 2011

Journal Articles

The PI3K pathway drives the maturation of mast cells via microphthalmia transcription factor

Peilin Ma, Raghuveer Singh Mali, Veerendra Munugalavadla, Subha Krishnan, Baskar Ramdas, Emily Sims, Holly Martin, Joydeep Ghosh, Shuo Li, Rebecca J. Chan, Gerald Krystal, Andrew W. Craig, Clifford Takemoto, Reuben Kapur

Blood (2011) 118 (13): 3459–3469.

https://doi.org/10.1182/blood-2011-04-351809

Published: 2011

Journal Articles

KIT signaling regulates MITF expression through miRNAs in normal and malignant mast cell proliferation

Youl-Nam Lee, Stephanie Brandal, Pierre Noel, Erik Wentzel, Joshua T. Mendell, Michael A. McDevitt, Reuben Kapur, Melody Carter, Dean D. Metcalfe, Clifford M. Takemoto

Blood (2011) 117 (13): 3629–3640.

https://doi.org/10.1182/blood-2010-07-293548

Published: 2011

Includes: Supplemental data

Journal Articles

PIAS3 negatively regulates RANKL-mediated osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblasts

Tomohiro Hikata, Hironari Takaishi, Jiro Takito, Akihiro Hakozaki, Mitsuru Furukawa, Shinichi Uchikawa, Tokuhiro Kimura, Yasunori Okada, Masahito Matsumoto, Akihiko Yoshimura, Riko Nishimura, Sakamuri V. Reddy, Hiroshi Asahara, Yoshiaki Toyama

Blood (2009) 113 (10): 2202–2212.

https://doi.org/10.1182/blood-2008-06-162594

Published: 2009

Includes: Supplemental data

Journal Articles

Differential context-dependent effects of friend of GATA-1 (FOG-1) on mast-cell development and differentiation

Daijiro Sugiyama, Makoto Tanaka, Kenji Kitajima, Jie Zheng, Hilo Yen, Tomotaka Murotani, Atsushi Yamatodani, Toru Nakano

Blood (2008) 111 (4): 1924–1932.

https://doi.org/10.1182/blood-2007-08-104489

Published: 2008

Includes: Supplemental data

Journal Articles

MafB negatively regulates RANKL-mediated osteoclast differentiation

Kabsun Kim, Jung Ha Kim, Junwon Lee, Hye Mi Jin, Hyun Kook, Kyung Keun Kim, Soo Young Lee, Nacksung Kim

Blood (2006) 109 (8): 3253–3259.

https://doi.org/10.1182/blood-2006-09-048249

Published: 2006

Includes: Supplemental data

Journal Articles

Kit Signaling Regulates Mitf Expression in Mastocytosis.

Youl-Nam Lee, PhD, Pierre Noel, M.D., Amir Shahlaee, M.D., Melody Carter, M.D., Reuben Kapur, Ph.D., Alan Wayne, M.D., Dean D. Metcalfe, M.D., Clifford Takemoto, M.D.

Blood (2006) 108 (11): 3601.

https://doi.org/10.1182/blood.V108.11.3601.3601

Published: 2006

NARROW

Loss of Dnmt3a Dysregulates Hematopoietic Homeostasis and Myeloid Skewing Via the PI3Kinase Pathway: PI3Kα/β Inhibition Corrects Extramedullary Hematopoiesis and Myeloid Skewing Due to Loss of Dnmt3a

Temporal and Spatially Regulated Oncogenic KIT Expression and Loss of Dnmt3a Cooperate to Drive MPN Development: Role of PI3Kinase in Dnmt3a Loss Induced Hyperproliferation in Myeloid Cells

Integrated Analysis of Global DNA Methylation and Transcription Reveals a Leukemia Subtype with Extreme Hypermethylation Associated with Silencing of Regulators of Differentiation

tfec controls the hematopoietic stem cell vascular niche during zebrafish embryogenesis

Genomic-Wide Analysis By High Resolution SNP Array Identifies Novel Genomic Alteration in Acute Myeloid Leukemia

CD26 Is a Novel Target for the Treatment of Tumor Progression and Its Related Osteolytic Bone Disease in Multiple Myeloma

Novel Functional Roles for Ten-Eleven-Translocation 2 (Tet2) in Normal and Leukemic Growth of Mast Cells

BCR-ABL Tyrosine Kinase Inhibitors Interfere with the PI3K/Akt Signalling Pathway and Activate the Microphthalmia-Associated Transcription Factor (MITF) in Human Dendritic Cells

Humanized Anti-CD26 Monoclonal Antibody Inhibits Osteoclast Bone Resorption Activity Via Blockade Of P38MAPK Signaling In Multiple Myeloma

Ikaros limits basophil development by suppressing C/EBP-α expression

A novel role of BMP4 in adult hematopoietic stem and progenitor cell homing via Smad independent regulation of integrin-α4 expression

Targeting CD26 with Humanized Monoclonal Antibody, As a Novel Approach to Inhibit Human Osteoclast Differentiation and Subsequent Bone Resorption

Molecular Characterization of the Leukemic Niche in Chronic Myeloid Leukemia (CML) and Evaluation of a Leukemia / Niche Cross-Talk

A Novel Osteoclastic Network Determines In Vitro Niche for Mouse and Human Hematopoietic Stem Cells

The PI3K pathway drives the maturation of mast cells via microphthalmia transcription factor

KIT signaling regulates MITF expression through miRNAs in normal and malignant mast cell proliferation

PIAS3 negatively regulates RANKL-mediated osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblasts

Differential context-dependent effects of friend of GATA-1 (FOG-1) on mast-cell development and differentiation

MafB negatively regulates RANKL-mediated osteoclast differentiation

Kit Signaling Regulates Mitf Expression in Mastocytosis.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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