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Journal Articles

Preclinical Evaluation for Engraftment of Gene-Edited CD34+ Cells with a Sickle Cell Disease Mutation in a Rhesus Transplantation Model

Naoya Uchida, MD, Linhong Li, PhD, Tina Nassehi, Morgan Yapundich, Jackson Gamer, Claire Drysdale, Juan J. Haro-Mora, PhD, Selami Demirci, PhD, Aylin Bonifacino, MS, Allen Krouse, Nathaniel S. Linde, Cornell Allen, MS, Suk See De Ravin, MD, PhD, Robert E. Donahue, VMD, Harry L. Malech, MD, Madhusudan Peshwa, PhD, John F. Tisdale, MD

Blood (2019) 134 (Supplement_1): 609.

https://doi.org/10.1182/blood-2019-122727

Published: 2019

Journal Articles

AAV8-Specific Immune Adsorption Column: A Treatment Option for Patients with Pre-Existing Anti-AAV8 Neutralizing Antibodies

Anita Kruzik, PhD, Roland Raim, PhD, Dirk Voelkel, PhD, Markus Weiller, PhD, Werner Hoellriegl, PhD, Friedrich Scheiflinger, Hanspeter Rottensteiner, Birgit M Reipert, PhD, Maurus de la Rosa

Blood (2019) 134 (Supplement_1): 5922.

https://doi.org/10.1182/blood-2019-126730

Published: 2019

Journal Articles

Truncated Erythropoietin Receptors Confer an In Vivo Selective Advantage in Gene-Modified Erythroid Cells Expressing Fetal Hemoglobin Due to BCL11A Interference

Naoya Uchida, MD, Claire Drysdale, Morgan Yapundich, Jackson Gamer, Tina Nassehi, Matthew Wielgosz, Francesca Ferrara, PhD, Juan J. Haro-Mora, PhD, Selami Demirci, PhD, Aylin Bonifacino, MS, Allen Krouse, Nathaniel S. Linde, Robert E. Donahue, VMD, Byoung Y. Ryu, PhD, John F. Tisdale, MD

Blood (2019) 134 (Supplement_1): 2063.

https://doi.org/10.1182/blood-2019-122770

Published: 2019

Journal Articles

Preclinical Development of an Actinium-225-Labeled Antibody Radio-Conjugate Directed Against CD45 for Targeted Conditioning and Radioimmunotherapy

Dale Ludwig, PhD BS, Ruth Bryan, Wojciech Dawicki, PhD, Eileen M Geoghegan, Qing Liang, PhD, Sandesh Seth, MS, MBA, Mamata Gokhale, Mark S. Berger, MD, Vijay Reddy, MD PhD, Ravendra Garg, Kevin Allen, PhD, Ekaterina Dadachova

Blood (2019) 134 (Supplement_1): 5601.

https://doi.org/10.1182/blood-2019-128678

Published: 2019

Journal Articles

Durable and Robust Fetal Globin Induction without Anemia in Rhesus Monkeys Following Autologous Hematopoietic Stem Cell Transplant with BCL11A Erythroid Enhancer Editing

Blood (2019) 134 (Supplement_1): 4632.

https://doi.org/10.1182/blood-2019-129394

Published: 2019

Journal Articles

Targeting a Specific Glycosylated Epitope of CD43 with a New Humanized Monoclonal Antibody for the Treatment of Pediatric and Adult T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Cirino Botta, MD, Giuseppe Gaipa, PhD, Maria Eugenia Gallo Cantafio, PhD, Chiara Buracchi, PhD, Maria Anna Siciliano, MD, Caterina Riillo, MD, Katia Grillone, PhD, Alessandro Gulino, Maria Cucè, Nicoletta Staropoli, Andrea Ghelli Luserna Di Rora, Franca Maria Tuccillo, Maria Teresa Di Martino, Claudio Tripodo, MD, Marco Rossi, MD, Giovanni Martinelli, Andrea Biondi, MD, Pierosandro Tagliaferri, Pierfrancesco Tassone, MD

Blood (2018) 132 (Supplement 1): 1418.

https://doi.org/10.1182/blood-2018-99-118572

Published: 2018

Journal Articles

Modeling Human Paroxysmal Nocturnal Hemoglobinuria Via CRISPR/Cas9 HSPC Gene Editing in Non-Human Primate

Taehoon Shin, PhD, Eun Jung Baek, MD, Marcus A.F. Corat, PhD, Shirley Chen, BS, Robert E. Donahue, VMD, Kyung-Rok Yu, PhD, Cynthia E. Dunbar, MD

Blood (2018) 132 (Supplement 1): 1309.

https://doi.org/10.1182/blood-2018-99-111984

Published: 2018

Journal Articles

The impact of aging on primate hematopoiesis as interrogated by clonal tracking

Kyung-Rok Yu, Diego A. Espinoza, Chuanfeng Wu, Lauren Truitt, Tae-Hoon Shin, Shirley Chen, Xing Fan, Idalia M. Yabe, Sandhya Panch, So Gun Hong, Samson Koelle, Rong Lu, Aylin Bonifacino, Allen Krouse, Mark Metzger, Robert E. Donahue, Cynthia E. Dunbar

Blood (2018) 131 (11): 1195–1205.

https://doi.org/10.1182/blood-2017-08-802033

Published: 2018

Includes: Supplemental data

Journal Articles

A Non-Human Primate CRISPR/Cas9 Model of Clonal Hematopoiesis of Indeterminate Potential Demonstrates Expansion of TET2-Disrupted Clones

Kyung-Rok Yu, PhD, Cynthia E Dunbar, MD, Marcus Corat, Shirley Chen, Aisha Aljanahi, Eun Jung Baek, Jean-Yves Metais, Hannah Natanson, Thomas Winkler, MD, Robert E Donahue, VMD

Blood (2017) 130 (Supplement 1): 117.

https://doi.org/10.1182/blood.V130.Suppl_1.117.117

Published: 2017

Journal Articles

Aberrant Clonal Hematopoiesis of the Erythroid and Myeloid Lineages in a Lentivirally Barcoded Rhesus Macaque

Diego A Espinoza, BA, Chuanfeng Wu, MD, Xing Fan, MD, Di Yang, MD, Idalia Montano Yabe, MS, Selami Demirci, PhD, So Gun Hong, PhD, Aylin Bonifacino, MS, Allen Krouse, Mark Metzger, Rong Lu, PhD, Katherine R Calvo, MD PhD, John F Tisdale, MD, Xiaolin Wu, PhD, Suk See De Ravin, MD PhD, Harry L Malech, MD, Robert E Donahue, VMD, Cynthia E Dunbar, MD

Blood (2017) 130 (Supplement 1): 606.

https://doi.org/10.1182/blood.V130.Suppl_1.606.606

Published: 2017

Journal Articles

Clonal Tracking of the Source of Red Cell and Platelet Production in Rhesus Macaques

Xing Fan, MD, Chuanfeng Wu, MD, Diego Espinoza, Stephanie Sellers, Aylin Bonifacino, MS, Robert E Donahue, VMD, Luca Schifanella, Genoveffa Franchini, Cynthia E Dunbar, MD

Blood (2017) 130 (Supplement 1): 932.

https://doi.org/10.1182/blood.V130.Suppl_1.932.932

Published: 2017

Journal Articles

Strict tropism for CD71 + /CD234 + human reticulocytes limits the zoonotic potential of Plasmodium cynomolgi

Varakorn Kosaisavee, Rossarin Suwanarusk, Adeline C. Y. Chua, Dennis E. Kyle, Benoit Malleret, Rou Zhang, Mallika Imwong, Rawiwan Imerbsin, Ratawan Ubalee, Hugo Sámano-Sánchez, Bryan K. S. Yeung, Jessica J. Y. Ong, Eric Lombardini, François Nosten, Kevin S. W. Tan, Pablo Bifani, Georges Snounou, Laurent Rénia, Bruce Russell

Blood (2017) 130 (11): 1357–1363.

https://doi.org/10.1182/blood-2017-02-764787

Published: 2017

Includes: Supplemental data

Journal Articles

Phylogenetic Analysis Identifies a Subset of ADAMTS13 Domains That Are Highly Conserved and Essential for Allosteric Regulation

Joshua Muia, PhD, Jian Zhu, PhD, Suellen Greco, DVM, Karen Vanhoorelbeke, PhD, Louis Deforche, PhD, Lisa Westfield, Garima Tyagi, PhD, J. Evan Sadler, MD PhD

Blood (2016) 128 (22): 1385.

https://doi.org/10.1182/blood.V128.22.1385.1385

Published: 2016

Journal Articles

Hematopoietic Stem Cell Infected with HTLV-1 Functions As a Viral Reservoir In Vivo

Jun-ichirou Yasunaga, MDPhD, Rie Furuta, Michi Miura, Kenji Sugata, Akatsuki Saito, Akari Hirofumi, Takaharu Ueno, Norihiro Takenouchi, Jun-ichi Fujisawa, Masakazu Shimizu, Fumihiko Matsuda, MD PhD, Anat Melamed, Charles R. M. Bangham, Masao Matsuoka, MD PhD

Blood (2016) 128 (22): 1343.

https://doi.org/10.1182/blood.V128.22.1343.1343

Published: 2016

Journal Articles

Clonal Expansion and Long-Term Persistence of Rhesus Macaque NK Cells with an Adaptive Phenotype

Chuanfeng Wu, MDPhD, Diego A Espinoza, Samson J. Koelle, BA, Di Yang, MD, Heinrich Schlums, Jan K. Davidson-Moncada, MD PhD, Rong Lu, Amitinder Kaur, Hammer Quirin, Brian Li, Sandhya R. Panch, MD MPH, Robert E Donahue, Richard W. Childs, Chiara Romagnani, Yenan Bryceson, Cynthia E. Dunbar, MD

Blood (2016) 128 (22): 549.

https://doi.org/10.1182/blood.V128.22.549.549

Published: 2016

Journal Articles

Coupling Therapeutics to Human Erythrocytes Demonstrates Target-Dependent Effects on Red Cell Physiology While Preserving Efficacy

Carlos Hipolito Villa, MD PhD, Daniel Pan, PhD, Ian Johnston, BS, Colin F Greineder, MD PhD, Marion E. Reid, PhD, Douglas B. Cines, MD, Mortimer Poncz, MD, Don L. Siegel, MD, PhD,, Vladimir R Muzykantov, MD PhD

Blood (2016) 128 (22): 701.

https://doi.org/10.1182/blood.V128.22.701.701

Published: 2016

Journal Articles

Long-term multilineage engraftment of autologous genome-edited hematopoietic stem cells in nonhuman primates

Christopher W. Peterson, Jianbin Wang, Krystin K. Norman, Zachary K. Norgaard, Olivier Humbert, Collette K. Tse, Jenny J. Yan, Richard G. Trimble, David A. Shivak, Edward J. Rebar, Philip D. Gregory, Michael C. Holmes, Hans-Peter Kiem

Blood (2016) 127 (20): 2416–2426.

https://doi.org/10.1182/blood-2015-09-672337

Published: 2016

Includes: Supplemental data

Journal Articles

Adeno-Associated Viral Vector Delivery of Optimized Human Factor VIII Achieves Therapeutic Factor VIII Levels in Non-Human Primates

Xavier M. Anguela, PhD, Liron Elkouby, PhD, Raffaella Toso, PhD, Marti DiPietro, MS, Robert J. Davidson, Katherine A. High, MD, Denise E. Sabatino, PhD

Blood (2015) 126 (23): 199.

https://doi.org/10.1182/blood.V126.23.199.199

Published: 2015

Journal Articles

The Impact of Aging of Hematopoietic Stem and Progenitor Cells (HSPCs) in Non-Human Primates As Interrogated By Genetic Barcode Clonal Tracking

Kyung-Rok Yu, PhD, Chuanfeng Wu, PhD, Diego Espinoza, Idalia Yabe, Sandhya R. Panch, MD MPH, So Gun Hong, PhD, Samson Jonathan Koelle, BA, Rong Lu, Aylin Bonifacino, Alan Krouse, Mark Metzger, Robert Donahue, VMD, Cynthia E. Dunbar, MD

Blood (2015) 126 (23): 1151.

https://doi.org/10.1182/blood.V126.23.1151.1151

Published: 2015

Journal Articles

Maintenance of Leukocyte Telomere Length after Transplant and Chemoselection in Macaques with Polyclonal Gene Modified Cell Engraftment

Jennifer E Adair, PhD, Christopher R Burtner, PhD, Hans-Peter Kiem, MD

Blood (2015) 126 (23): 3236.

https://doi.org/10.1182/blood.V126.23.3236.3236

Published: 2015

NARROW

Preclinical Evaluation for Engraftment of Gene-Edited CD34+ Cells with a Sickle Cell Disease Mutation in a Rhesus Transplantation Model

AAV8-Specific Immune Adsorption Column: A Treatment Option for Patients with Pre-Existing Anti-AAV8 Neutralizing Antibodies

Truncated Erythropoietin Receptors Confer an In Vivo Selective Advantage in Gene-Modified Erythroid Cells Expressing Fetal Hemoglobin Due to BCL11A Interference

Preclinical Development of an Actinium-225-Labeled Antibody Radio-Conjugate Directed Against CD45 for Targeted Conditioning and Radioimmunotherapy

Durable and Robust Fetal Globin Induction without Anemia in Rhesus Monkeys Following Autologous Hematopoietic Stem Cell Transplant with BCL11A Erythroid Enhancer Editing

Targeting a Specific Glycosylated Epitope of CD43 with a New Humanized Monoclonal Antibody for the Treatment of Pediatric and Adult T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Modeling Human Paroxysmal Nocturnal Hemoglobinuria Via CRISPR/Cas9 HSPC Gene Editing in Non-Human Primate

The impact of aging on primate hematopoiesis as interrogated by clonal tracking

A Non-Human Primate CRISPR/Cas9 Model of Clonal Hematopoiesis of Indeterminate Potential Demonstrates Expansion of TET2-Disrupted Clones

Aberrant Clonal Hematopoiesis of the Erythroid and Myeloid Lineages in a Lentivirally Barcoded Rhesus Macaque

Clonal Tracking of the Source of Red Cell and Platelet Production in Rhesus Macaques

Strict tropism for CD71 + /CD234 + human reticulocytes limits the zoonotic potential of Plasmodium cynomolgi

Phylogenetic Analysis Identifies a Subset of ADAMTS13 Domains That Are Highly Conserved and Essential for Allosteric Regulation

Hematopoietic Stem Cell Infected with HTLV-1 Functions As a Viral Reservoir In Vivo

Clonal Expansion and Long-Term Persistence of Rhesus Macaque NK Cells with an Adaptive Phenotype

Coupling Therapeutics to Human Erythrocytes Demonstrates Target-Dependent Effects on Red Cell Physiology While Preserving Efficacy

Long-term multilineage engraftment of autologous genome-edited hematopoietic stem cells in nonhuman primates

Adeno-Associated Viral Vector Delivery of Optimized Human Factor VIII Achieves Therapeutic Factor VIII Levels in Non-Human Primates

The Impact of Aging of Hematopoietic Stem and Progenitor Cells (HSPCs) in Non-Human Primates As Interrogated By Genetic Barcode Clonal Tracking

Maintenance of Leukocyte Telomere Length after Transplant and Chemoselection in Macaques with Polyclonal Gene Modified Cell Engraftment

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American Society of Hematology

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American Society of Hematology

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