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Journal Articles

SASH3 variants cause a novel form of X-linked combined immunodeficiency with immune dysregulation

Clinical Trials & Observations
Ottavia M. Delmonte, Jenna R. E. Bergerson, Tomoki Kawai, Hye Sun Kuehn, David H. McDermott, Irene Cortese, Michael T. Zimmermann, A. Kerry Dobbs, Marita Bosticardo, Danielle Fink, Shamik Majumdar, Boaz Palterer, Francesca Pala, Nikita R. Dsouza, Marie Pouzolles, Naomi Taylor, Katherine R. Calvo, Stephen R. Daley, Daniel Velez, Anahita Agharahimi, Katherine Myint-Hpu, Lesia K. Dropulic, Jonathan J. Lyons, Steven M. Holland, Alexandra F. Freeman, Rajarshi Ghosh, Morgan B. Similuk, Julie E. Niemela, Jennifer Stoddard, Douglas B. Kuhns, Raul Urrutia, Sergio D. Rosenzweig, Magdalena A. Walkiewicz, Philip M. Murphy, Luigi D. Notarangelo
Journal: Blood
Blood (2021) 138 (12): 1019–1033.
https://doi.org/10.1182/blood.2020008629
Published: 2021
Includes: Supplemental data
Journal Articles

Development and survival of MYC-driven lymphomas require the MYC antagonist MNT to curb MYC-induced apoptosis

Hai Vu Nguyen, Cassandra J. Vandenberg, Ashley P. Ng, Mikara R. Robati, Natasha S. Anstee, Joel Rimes, Edwin D. Hawkins, Suzanne Cory
Journal: Blood
Blood (2020) 135 (13): 1019–1031.
https://doi.org/10.1182/blood.2019003014
Published: 2020
Includes: Supplemental data
Journal Articles

Single-Cell RNA Sequencing Reveals a Distinct Transcriptome Signature of Hematopoiesis in GATA2 Deficiency

Zhijie Wu, MD PhD, Shouguo Gao, PhD, Sachiko Kajigaya, PhD, Jinguo Chen, PhD, Rongye Shi, BS, Carrie Diamond, MD, Cindy Palmer, BSN, Amy P. Hsu, Katherine R. Calvo, MD PhD, Dennis D. Hickstein, MD, Steven M. Holland, MD, Neal S. Young, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3735.
https://doi.org/10.1182/blood-2019-124774
Published: 2019
Journal Articles

Preclinical Evaluation of ALLO-819, an Allogeneic CAR T Cell Therapy Targeting FLT3 for the Treatment of Acute Myeloid Leukemia

Cesar Sommer, PhD, Hsin-Yuan Cheng, PhD, Yik Andy Yeung, PhD, Duy Nguyen, Janette Sutton, Zea Melton, Julien Valton, PhD, Kris Poulsen, Ivana Djuretic, PhD, Thomas Van Blarcom, PhD, Javier Chaparro-Riggers, PhD, Barbra Sasu, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3921.
https://doi.org/10.1182/blood-2019-129025
Published: 2019
Journal Articles

Targeting Unique Synthetic Lethal Interactions between PI3K and MYC in B-ALL

Gang Xiao, PhD, Kohei Kume, PhD, Huimin Geng, PhD, Than Than Han, MS, Lars Klemm, MS, Markus Müschen, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3785.
https://doi.org/10.1182/blood-2019-128719
Published: 2019
Journal Articles

Preliminary Results from a Phase I Study of SHC014748M in Patients with Relapsed or Refractory Indolent B-Cell Lymphomas

Wei Xu, MD PhD, Jie Jin, MD PhD, Keshu Zhou, MD, Li Wang, MD, Huayuan Zhu, Jiejing Qian, Jianying Huang, Fuling Zhou, MD, Xiaohong Xu, Zhiqiang Wang, Wei Guo, Jianyong Li, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4000.
https://doi.org/10.1182/blood-2019-126707
Published: 2019
Journal Articles

Final Results of a Phase II Biomarker-Driven Study of Ruxolitinib in Relapsed and Refractory T-Cell Lymphoma

Alison J. Moskowitz, MD, Paola Ghione, MD, Eric D Jacobsen, MD, Jia Ruan, MD PhD, Jonathan H. Schatz, MD, Sarah Noor, MD, Patricia Myskowski, Helen Hancock, ANP, Theresa Davey, MMSc, PA-C, Obadi Obadi, Carlissa Onwasigwe, MPH, Nivetha Ganesan, MPH, Lauren Pomerantz, BS, Christine Jarjies, MS, Priyadarshini Kumar, Allison Sigler, Mark B. Geyer, MD, Ariela Noy, MD, David J. Straus, MD, Travis Hollmann, MD, Ahmet Dogan, MD PhD, Natasha Galasso, Giorgio Inghirami, MD, David M. Weinstock, MD, Steven M. Horwitz, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4019.
https://doi.org/10.1182/blood-2019-125017
Published: 2019
Journal Articles

Splenic Marginal Zone Lymphoma: Risk of Transformation, Clinico-Biological Features at Transformation and Prognosis

Gabriela Bastidas, MD, Silvia Bea, PhD, Alba Navarro, Eva Gine, MD, Julio Delgado, Tycho Baumann, Alfredo Rivas-Delgado, MD, Laura Magnano, MD, Neus Villamor, Dolors Costa, MD, Colomer Dolors, Monica Lopez-Guerra, María Rozman, MD, Daniel Martínez, MD, Balagué Olga, Maria Joao Baptista, PhD PharmD, Miguel Alcoceba, Lourdes Escoda, MD, Andrew Wotherspoon, MB BCh, Elias Campo, Armando Lopez-Guillermo, Estella Matutes, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4015.
https://doi.org/10.1182/blood-2019-127199
Published: 2019
Journal Articles

Imatinib in Children with Chronic Myeloid Leukemia in Chronic Phase: Long-Term Results of the French National Phase IV Trial

Hélène Deutsch, MD, Andre Baruchel, Joelle Guilhot, PhD, Arnaud Petit, MD PhD, Thierry Leblanc, MD, Yves Bertrand, MD, Brigitte Nelken, MD, Catherine Paillard, MD PhD, Cécile Verite, MD, Yves Réguerre, MD, Francoise Mechinaud, MD FRACP, Francois Guilhot, MD, Frederic Millot
Journal: Blood
Blood (2019) 134 (Supplement_1): 4147.
https://doi.org/10.1182/blood-2019-124060
Published: 2019
Journal Articles

Preliminary Results from a Phase 2 Trial of Brentuximab Vedotin Plus Cyclophosphamide, Doxorubicin, Etoposide, and Prednisone (CHEP-BV) Followed By BV Consolidation in Patients with CD30-Positive Peripheral T-Cell Lymphomas

Alex F. Herrera, MD, Jasmine Zain, MD, Kerry J Savage, BSc, MD MSc, Tatyana A. Feldman, MD, Jonathan E Brammer, MD, Lu Chen, PhD, Leslie L. Popplewell, MD FRCPA, Lihua E Budde, MD PhD, Lacolle Peters, Yaira Kurtzman, Stephen J Forman, MD, Steven Rosen, MD, Larry W Kwak, MD PhD, Swaminathan P. Iyer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4023.
https://doi.org/10.1182/blood-2019-123166
Published: 2019
Journal Articles

Outcomes of First-Line Treatment (FL) of Classical Hodgkin Lymphoma (cHL) in Argentina: A Real Life Multicenter Retrospective Study

Victoria Otero, MD, Carolina Valeria Mahuad, MD PhD, Laura Korin, MD, Enriqueta Martinez, MD, Fernando Warley, MSc, MD, Hernán García Rivello, Nancy Cristaldo, MD, Dana Kohan, Marta Zerga, MD, Gonzalo Martin Garate, MD, Maria De Los Angeles Vicente Reparaz, Maria Florencia Aizpurua, MD, Erica Rojas Bilbao, Susana Cerana, Maria Eugenia Funes, Iliana Plaza, Maria Cecilia Foncuberta, MD, Anahí Vijnovich Baron, MD, Santiago Cranco, MD, Adriana Vitriu, MD, Mariela Gomez, Justina Lavalle, Claudia Casali, MD, Manuela Clavijo, Luciana Melillo, MD, Maria Cecilia Cabral Lorenzo, Augusto Miroli, MD PhD, Laura Fishman, Maximiliano J. Pavlove, MD PhD, Marcela Miodosky, Silvana Cugliari
Journal: Blood
Blood (2019) 134 (Supplement_1): 4046.
https://doi.org/10.1182/blood-2019-126314
Published: 2019
Journal Articles

Phase 2 Study of E7777, a Diphtheria Toxin Fragment-Interleukin-2 Fusion Protein, in Japanese Patients with Relapsed or Refractory Peripheral and Cutaneous T-Cell Lymphoma

Dai Maruyama, MD PhD, Kiyoshi Ando, Kazuhito Yamamoto, Eiji Kiyohara, MD, Yasuhito Terui, MD PhD, Noriko Fukuhara, MD PhD, Tomomitsu Miyagaki, MD PhD, Hidetsugu Kawai, MD, Yoshiki Tokura, MD PhD, Mamiko Sakata-Yanagimoto, MD PhD, Tadahiko Igarashi, MD PhD, Junya Kuroda, MD PhD, Jiro Fujita, MD PhD, Toshiki Uchida, MD PhD, Takayuki Ishikawa, MD PhD, Kentaro Yonekura, MD PhD, Koji Kato, MD PhD, Tadashi Nakanishi, Kenya Nakai, Risa Matsunaga, Kensei Tobinai, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4032.
https://doi.org/10.1182/blood-2019-121723
Published: 2019
Journal Articles

Glucocorticoids Regulate the Splicing Factor MBNL1, a Potential Control Point for B-Cell Specification

Miles A. Pufall, PhD, Mimi Fang, Robert K. Bradley, PhD, Chew Guo-Liang, Ross Lanier, Sarah K. Tasian, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2478.
https://doi.org/10.1182/blood-2019-131322
Published: 2019
Journal Articles

A Phase 1b/2 Study of Chidamide Combined with CHOP in Previously Untreated Patients with Peripheral T-Cell Lymphoma (PTCL)

Yuankai Shi, MD, Lin Gui, MD, Junning Cao, MD, Huilai Zhang, MD, Jun Zhu, MD PhD, Dongmei Ji, MD PhD, Qian Fan, MD, Yuqin Song, MD PhD, Weina Shen, MM, Guiying Bai, MM, Ming-Zhe Han, MD, Shiyu Jiang
Journal: Blood
Blood (2019) 134 (Supplement_1): 2840.
https://doi.org/10.1182/blood-2019-128078
Published: 2019
Journal Articles

Clinical Response in Relapsed/Refractory (R/R) B-NHL Treated with the CD19-Directed CAR T-Cell Product JWCAR029

Zhitao Ying, MD PhD, Pengpeng Xu, MD, Li Wang, MD PhD, Shu Cheng, MD PhD, Wen Wu, MD PhD, Wen Wang, MD PhD, Ming Hao, PhD, Su Yang, Harry Lam, PhD, James Li, Hongxia Zheng, MD PhD, Weili Zhao, MD PhD, Yuqin Song, MD PhD, Jun Zhu, BS
Journal: Blood
Blood (2019) 134 (Supplement_1): 2876.
https://doi.org/10.1182/blood-2019-127751
Published: 2019
Journal Articles

Safety and Efficacy of Mitoxantrone Hydrochloride Liposome in Patients with Relapsed or Refractory Peripheral T-Cell Lymphoma and Extranodal NK/T-Cell Lymphoma: A Multicenter, Single-Arm, Open-Label, Phase 2 Clinical Trial

Hui-qiang Huang, Yunhong Huang, MD PhD, Gao Yan, Haiyan Yang, Qingyuan Zhang, Runxiang Yang, Min Zhou, PhD, Yufu Li, Yan Li, Lihong Liu, Hui Zhou, MD PhD, Hongmei Jing, Zhigang Peng, MD, Ding Yu, Rong yan Zhang, Bing Xu, Xiaohong Zhang, Junyuan Qi, Liping MA, MD, Shan Chen, Jianfei Xue
Journal: Blood
Blood (2019) 134 (Supplement_1): 2838.
https://doi.org/10.1182/blood-2019-126481
Published: 2019
Journal Articles

Prognostic Value of Lymphopenia and Lymphocytosis after Peripheral Blood Haplo-Identical Stem Cell Transplantation

Yannick LE Bris, PharmD, Thierry Guillaume, MD PhD, Camille Debord, PharmD, Pierre Peterlin, Soraya Wuilleme, PharmD, PhD, Céline Bressollette, MD PhD, Amandine Le Bourgeois, MD, Alice Garnier, MD, Aurélie Fantou, PharmD, Marie Audrain, MD PhD, Audrey Ménard, Nelly Robillard, PhD, Marion Eveillard, Steven Le Gouill, Berthe Marie Imbert, PharmD, PhD, Marie C Bene, PharmSciD, PhD, Patrice Chevallier, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3319.
https://doi.org/10.1182/blood-2019-122093
Published: 2019
Journal Articles

Combination Chemotherapy with Carfilzomib, Bendamustine and Dexamethasone Is Highly Active for Therapy of Newly Diagnosed Multiple Myeloma-Results of Single Center Phase I/II Study

Divaya Bhutani, MD, Siyang Leng, MD, Samuel Pan, Amer Assal, MD, Alexander Wei, Julia Gould, BA, Markus Y. Mapara, MD PhD, Suzanne Lentzsch, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3196.
https://doi.org/10.1182/blood-2019-130207
Published: 2019
Journal Articles

Safety Analysis of Five Randomized Controlled Studies of Daratumumab in Patients with Multiple Myeloma

Samer Al Hadidi, MDMSc, Rammurti Kamble, MD, Courtney Nicole Miller-Chism, MD, Martha P. Mims, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3175.
https://doi.org/10.1182/blood-2019-126341
Published: 2019
Journal Articles

A Phase 1/2 Study to Assess Safety and Dose of Ixazomib in Combination with Cyclophosphamide and Dexamethasone in Newly Diagnosed Patients with Light Chain (AL) Amyloidosis

Larysa Sanchez, MD, Heather J Landau, MD, Cara A. Rosenbaum, MD, Alex Abrahams, Cindy Chin, Brielle Liotta, BS, Natalie Agudo, RN, Sheetal Ramnath, Elizabeth Hoover, BS, Hafsa Rahman, Umut Ozbek, PhD, Oscar B Lahoud, MD, Hani Hassoun, MD, Keren Osman, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3128.
https://doi.org/10.1182/blood-2019-126023
Published: 2019