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Journal Articles

Real-world use of thrombopoietin receptor agonists in older patients with primary immune thrombocytopenia

Free
Clinical Trials & Observations
Francesca Palandri, Elena Rossi, Daniela Bartoletti, Antonietta Ferretti, Marco Ruggeri, Elisa Lucchini, Valentina Carrai, Wilma Barcellini, Andrea Patriarca, Elena Rivolti, Ugo Consoli, Silvia Cantoni, Esther Natalie Oliva, Federico Chiurazzi, Giovanni Caocci, Gaetano Giuffrida, Alessandra Borchiellini, Giuseppe Auteri, Erminia Baldacci, Giuseppe Carli, Daniela Nicolosi, Emanuele Sutto, Monica Carpenedo, Michele Cavo, Maria Gabriella Mazzucconi, Francesco Zaja, Valerio De Stefano, Francesco Rodeghiero, Nicola Vianelli
Journal: Blood
Blood (2021) 138 (7): 571–583.
https://doi.org/10.1182/blood.2021010735
Published: 2021
Includes: Supplemental data
Journal Articles

MPL mutations in essential thrombocythemia uncover a common path of activation with eltrombopag dependent on W491

Free
Brief Report
Gabriel Levy, Serge Carillo, Benjamin Papoular, Bruno Cassinat, Jean-Marc Zini, Emilie Leroy, Leila N. Varghese, Ilyas Chachoua, Jean-Philippe Defour, Steven O. Smith, Stefan N. Constantinescu
Journal: Blood
Blood (2020) 135 (12): 948–953.
https://doi.org/10.1182/blood.2019003240
Published: 2020
Includes: Supplemental data
Journal Articles

Eltrombopag for immune thrombocytopenia secondary to chronic lymphoproliferative disorders: a phase 2 multicenter study

Free
Clinical Trials & Observations Brief Report
Carlo Visco, Francesco Rodeghiero, Alessandra Romano, Federica Valeri, Michele Merli, Giulia Quaresimini, Stefano Volpetti, Roberto M. Santi, Giuseppe Carli, Elisa Lucchini, Francesco Passamonti, Alessandro Rambaldi, Giovanna Motta, Alessandra Borchiellini, Emanuele S. G. d’Amore, Marco Ruggeri
Journal: Blood
Blood (2019) 134 (20): 1708–1711.
https://doi.org/10.1182/blood.2019001617
Published: 2019
Includes: Supplemental data
Journal Articles

Influence of Age on Treatment with Thrombopoietin Receptor Agonists in Patients with Immune Thrombocytopenia; A Retrospective Multicenter Study

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Maria Luisa Lozano, MD PhD, Maria Eva Mingot-Castellano, PhD MD, María Perera, MD, Isidro Jarque, Rosa Maria Campos, Tomás José González-López, MD, Gonzalo Carreño Gomez-Tarragona, Nuria Bermejo, MD, Maria Fernanda Lopez Fernandez, Aurora de Andrés, David Valcarcel, MD, Felipe Casado, Teresa Álvarez Roman, María Isabel Orts, MD, Silvana Novelli, MD, Jose Ramon González-Porras, MD PhD, Estefanía Bolaños, Manuel Rodríguez López, MD, Elisa Orna, Vicente Vicente Garcia, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2361.
https://doi.org/10.1182/blood-2019-122237
Published: 2019
Journal Articles

No Increased Risk of Cataract in Immune Thrombocytopenia Adult Patients Treated with Eltrombopag. a French Nationwide Nested Case-Control Study

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Margaux Lafaurie, PharmD, Bérangère Baricault, Vincent Soler, MD PhD, Myriam Cassagne, MD PhD, Laurent Sailler, MD PhD, Maryse Lapeyre-Mestre, MD PhD, Agnès Sommet, MD PhD, Guillaume Moulis, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2363.
https://doi.org/10.1182/blood-2019-124729
Published: 2019
Journal Articles

Eltrombopag: More Than Just a Thrombopoietin Receptor Agonist (TPO-RA) in Immune Thrombocytopenia (ITP)

Free
Anwar A. Sayed, MBBS, MSc, PhD, Amna Malik, PhD, Grace Ayoola, BSc., Elisa Lucchini, MD, Sasfia Candrianita, MD, Michelle H Tan, BSc, Camelia Vladescu, MSc, Deena Paul, Alice C J Hart, MBBS, BSc, MRCP, FRCPath(Haem), Ahmad Khoder, MD PhD MRCP, ASCP, Nesrina Imami, PhD, Nichola Cooper, MD MRCP
Journal: Blood
Blood (2019) 134 (Supplement_1): 2364.
https://doi.org/10.1182/blood-2019-122848
Published: 2019
Journal Articles

A Phase 3 Study of Eltrombopag Vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia in Children

Free
Kristin A. Shimano, MD, Rachael F. Grace, MD, Carolyn M. Bennett, MDMSc, Robert J Klaassen, MD FRCPC, Cindy Neunert, MD, Ellis J. Neufeld, MD, Clement Ma, PhD, Wendy B. London, PhD, Jenny M. Despotovic, DO, MS
Journal: Blood
Blood (2019) 134 (Supplement_1): 2369.
https://doi.org/10.1182/blood-2019-125487
Published: 2019
Journal Articles

Predictive Factors for Thrombopoietin Receptor Agonist Free Responses in Chronic ITP Patients: A Multicenter Retrospective Study with Long-Term Follow-up

Free
Maria Luisa Lozano, MD PhD, Maria Eva Mingot-Castellano, PhD MD, María Perera, MD, Isidro Jarque, Rosa Maria Campos, Tomás José González-López, MD, Gonzalo Carreño Gomez-Tarragona, Nuria Bermejo, MD, Maria Fernanda Lopez Fernandez, Aurora de Andrés, David Valcarcel, Felipe Casado, Teresa Álvarez Roman, María Isabel Orts, MD, Silvana Novelli, MD, Nuria Revilla, MD, Jose Ramon González-Porras, MD PhD, Estefanía Bolaños, Manuel Rodríguez López, MD, Elisa Orna, Vicente Vicente Garcia, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2370.
https://doi.org/10.1182/blood-2019-125580
Published: 2019
Journal Articles

Eltrombopag for Immune Thrombocytopenia Adult Patients in the Real-Life Practice in France. Interim Results of the Elextra Study

Free
Guillaume Moulis, MD PhD, Manuela Rueter, MSc, Margaux Lafaurie, PharmD, Maryse Lapeyre-Mestre, MD PhD, Carmen investigators Group
Journal: Blood
Blood (2019) 134 (Supplement_1): 2372.
https://doi.org/10.1182/blood-2019-126000
Published: 2019
Journal Articles

Long Term Discontinuation of Eltrombopag after Remission in Primary Immune Thrombocytopenia: 8-Year Follow-up Data from 15 Spanish Centers

Free
Tomas Jose Gonzalez-Lopez, Fernando Fernandez-Fuertes, Maria Cristina Pascual Izquierdo, PhD MD, Isabel Caparros, Silvia Bernat, Carmen Pastoriza, Maria Paz Martínez-Badas, Pável E Olivera, MD, Gonzalo Caballero, MD, Jose Angel Hernandez-Rivas, MD PhD, Daniel Martínez-Carballeira, MD, Inmaculada Soto Ortega, Gloria Perez Segura, Isabel Regalado, Blanca Sánchez-González, Isidro Jarque, Luis Javier garcia Frade, MD, Miguel A. Sanz
Journal: Blood
Blood (2019) 134 (Supplement_1): 2352.
https://doi.org/10.1182/blood-2019-129274
Published: 2019
Journal Articles

Reduced Intensity Conditioning for Haploidentical Transplantation Using Double Source of Hematopoietic Stem Cells and Post-Transplant Cyclophosphamide for Severe Aplastic Anemia

Free
Ana Rojas Fonseca, Vivian Aparecida Zanao, MD, Katya Parisio, MD, José Salvador Rodrigues de Oliveira, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5745.
https://doi.org/10.1182/blood-2019-131578
Published: 2019
Journal Articles

Spectrum and Clinical Significance of HLA Class I Alleles and Their Somatic Mutations in Immune Aplastic Anemia

Free
Yoshitaka Zaimoku, MD PhD, Sharon D. Adams, MT, CHS (ABHI), Bhavisha A Patel, MD, Audrey Ai Chin Lee, MS, CHT (ABHI), Sachiko Kajigaya, PhD, Xingmin Feng, PhD, Olga Rios, RN, Holly DiFebo, RN, Lemlem Alemu, BS, Diego Quinones Raffo, MSc, Emma M. Groarke, MD, Willy A. Flegel, MD, Neal S. Young, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3738.
https://doi.org/10.1182/blood-2019-127359
Published: 2019
Journal Articles

Long-Term Durability of Eltrombopag Clinical Benefit for Advanced Myelodysplastic Syndromes or Acute Myeloid Leukemia and Severe Thrombocytopenia (ASPIRE Part 3)

Free
Moshe Mittelman, MD, Uwe Platzbecker, MD, Boris Afanasyev, MD PhD, Sebastian Grosicki, MD PhD, Maria Socorro O Portella, MD MBA, Zewen Zhu, Dominik Selleslag, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3740.
https://doi.org/10.1182/blood-2019-130309
Published: 2019
Journal Articles

Phase II Study of Eltrombopag in Subjects with Fanconi Anemia

Free
Daisuke Araki, MD, Ma Evette Barranta, Fariba Chinian, MS, Julie Erb-Alvarez, MPH, Thomas Winkler, MD, Neelam Giri, MD, Andre Larochelle, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3753.
https://doi.org/10.1182/blood-2019-123151
Published: 2019
Journal Articles

Comparing the Risk of Complications for Second-Line Treatments of Immune Thrombocytopenia in Veterans: A U.S. National Study

Free
Natalia Ruiz-Negron, PharmD, Jacob Crook, MStat, Matthew T. Rondina, MD, Pallavi Patwardhan, PhD, Qayyim Said, PhD, Isha Desai, MPH, Richard Nelson, PhD, Joanne LaFleur, PharmD, MSPH
Journal: Blood
Blood (2019) 134 (Supplement_1): 85.
https://doi.org/10.1182/blood-2019-121894
Published: 2019
Journal Articles

UM171 Regulates the Hematopoietic Differentiation of Human Acquired Aplastic Anemia-Derived Induced Pluripotent Stem Cells

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Tellechea Maria Florencia, MSc, Flavia S. Donaires, PhD, Tiago C. Silva, PhD, Lilian F. Moreira, PhD, Yordanka Armenteros, PhD, Rodrigo T. Calado, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2500.
https://doi.org/10.1182/blood-2019-127466
Published: 2019
Journal Articles

Dose-Dependent Iron Chelating Effects of Eltrombopag on in Vitro Human Megakaryopoiesis

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Zhi-Jian Liu, PhD, Emoke Deschmann, MD, Haley E. Ramsey, PhDMSc, Henry Feldman, Bethan Psaila, MD PhD, Nichola Cooper, MD MRCP, Evangelia Vlachodimtropoulou Koumoutsea, MBBS,PhDBSc, John B. Porter, MA MDFRCP FRCPath, James B. Bussel, MD, Michael Georgieff, MD, Martha Sola-Visner, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2475.
https://doi.org/10.1182/blood-2019-131895
Published: 2019
Journal Articles

Long-Term Response Rates in Patients with Chronic Immune Thrombocytopenia Treated with Avatrombopag: Additional Analyses from a Phase 3 Study and Its Extension Phase

Free
Hanny Al-Samkari, MD, Kavita Aggarwal, PharmD, Michael Vredenburg, PhD, Wei Tian, PhD, Lee F. Allen, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2356.
https://doi.org/10.1182/blood-2019-131215
Published: 2019
Journal Articles

A Single Arm, Phase II Study of Eltrombopag to Enhance Platelet Count Recovery in Older Patients with Acute Myeloid Leukemia (AML) Undergoing Remission Induction Therapy

Free
Sudipto Mukherjee, MD PhD MPH, Hong Li, Brian P. Hobbs, PhD, Aaron T. Gerds, MD MS, Anjali S. Advani, MD, Hetty E. Carraway, MD MBA, Aziz Nazha, MD, Samjhana Bogati, RN, Eric Parsons, RN, Benjamin Pannell, Matt Kalaycio, MD, Yogenthiran Saunthararajah, MD, Jaroslaw P. Maciejewski, MD PhD, Mikkael A. Sekeres, MD MS
Journal: Blood
Blood (2019) 134 (Supplement_1): 2595.
https://doi.org/10.1182/blood-2019-132178
Published: 2019
Journal Articles

Long Term Effects of Eltrombopag Treatment Versus Placebo for Low-Risk Myelodysplastic Syndromes with Thrombocytopenia (EQoL-MDS): Interim Results of a Single-Blind, Randomised, Controlled, Phase 2 Superiority Trial

Free
Esther Natalie Oliva, MD, Caterina Alati, MD, Valeria Santini, MD, Antonella Poloni, PhD MD, Marta Riva, MD, Pasquale Niscola, MD PhD, Valentina Giai, MD, Grazia Sanpaolo, MD, Enrico Balleari, Elena Crisà, MD, Dario Ferrero, MD, Ulrich Germing, MD, Pierre Fenaux, MD PhD, Giuseppe A. Palumbo, MD PhD, Prassede Salutari, MD, Stefana Impera, MD, Isabella Capodanno, MD, Gianluigi Reda, MD, Anna Marina Liberati, Alfredo Molteni, MD, Giorgina Specchia, MD, Francesco Buccisano, MD, Maria Teresa Voso, MD, Stefano Mancini, MD, Monica Bocchia, Anna Candoni, MD, Bruno Martino, MD, Patrizia Cufari, Maria Grazia D'Errigo, Gina Zini, MD PhD, Roberto Latagliata
Journal: Blood
Blood (2019) 134 (Supplement_1): 3000.
https://doi.org/10.1182/blood-2019-126744
Published: 2019