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Journal Articles

Novel CD4 + CD8 + Umbilical Cord Blood Regulatory T Cells

Meixian Huang, Amit Verma, MBBS, Ke Zeng, MD PhD, Mi-Ae Lyu, PhD, Mitsutaka Nishimoto, MD PhD, Hongbing Ma, MD PhD, Zheng Yin, PhD, Swaminathan P. Iyer, MD, Simrit Parmar, MBBS

Blood (2019) 134 (Supplement_1): 4446.

https://doi.org/10.1182/blood-2019-131948

Published: 2019

Journal Articles

Lessons from Nature: A Novel Class of TET Inhibitors for TET2 Mutant Associated Diseases

Yihong Guan, Anand D. Tiwari, PhD, Metis Hasipek, PhD, Dale Grabowski, BS, Yvonne Parker, Cassandra M. Hirsch, Amy C Graham, BS, MS, Yasunobu Nagata, Bartlomiej P. Przychodzen, Aziz Nazha, Daniel Lindner, MD PhD, Tomas Radivoyevitch, PhD, James G Phillips, PhD, Jaroslaw P. Maciejewski, Babal K. Jha

Blood (2018) 132 (Supplement 1): 4345.

https://doi.org/10.1182/blood-2018-99-117186

Published: 2018

Journal Articles

Polycomb Group Proteins Recruit TET1 to Remove Aberrant DNA Methylation in Murine Embryonic Stem Cells

Yong Lei, PhD, Margaret A. Goodell, PhD

Blood (2018) 132 (Supplement 1): 2571.

https://doi.org/10.1182/blood-2018-99-116841

Published: 2018

Journal Articles

Pharmacologic LSD1 Inhibition Preserves Human Granulocytic While Expanding Monocytic Progenitors

Karlotta E Kahmann, Stefanie Kesper, Marco Luciani, Michael Möllmann, Hugh Y. Rienhoff, Jr., MD, Ulrich Dührsen, Prof, MD PhD, Joachim R Göthert, MD

Blood (2018) 132 (Supplement 1): 2645.

https://doi.org/10.1182/blood-2018-99-113887

Published: 2018

Journal Articles

Epigenetic Control of Foxp3, CAMTA1 and FUT7 Genes in Human Regulatory T Cells

Ekaterina Minskaia, PhD, Barbara C Saraiva, Maria Soares, PhD, Ana I.S. Vieira, MSc, Joao F Lacerda, MD PhD

Blood (2017) 130 (Supplement 1): 1004.

https://doi.org/10.1182/blood.V130.Suppl_1.1004.1004

Published: 2017

Journal Articles

Single-Cell Methylome and Transcriptome High-Resolution Maps Define the Effects of Epigenetic Modifiers on the Landscape of Hematopoietic Differentiation

Franco Izzo, PhD, Asaf Poran, Stanley Chun-Wei Lee, PhD, Ronan Chaligne, PhD, Federico Gaiti, PhD, Steven Kothen-Hill, MS, Rafael Schulman, BS, Michelle Ki, Kenigsberg Ephraim, PhD, Omar Abdel-Wahab, MD, Dan A. Landau, MD PhD

Blood (2017) 130 (Supplement 1): 559.

https://doi.org/10.1182/blood.V130.Suppl_1.559.559

Published: 2017

Journal Articles

Acute Deletion of Tet2 or Tet3 Transiently Dysregulate Murine Erythropoiesis

Aishwarya Swaminathan, PhD, Daniel Hidalgo, MA, Hien Nguyen, Scott Shaffer, Maria Figueroa, Jian Xu, PhD, Merav Socolovsky, MBBS, PhD

Blood (2017) 130 (Supplement 1): 11.

https://doi.org/10.1182/blood.V130.Suppl_1.11.11

Published: 2017

Journal Articles

TET2 and MSH6: A Novel Role for MMR in the Pathogenesis of Myeloid Malignancies

Edward F Greenberg, MD, Cassandra M. Hirsch, BS, Feng Pan, PhD, Babal K Jha, PhD, Yihong Guan, PhD, Valeria Visconte, PhD, Dewen You, PhD, Guangbo Qu, PhD, Amy Graham, Bartlomiej P. Przychodzen, MSc, Thomas Laframboise, PhD, Hideki Makishima, MD PhD, Daniel Gackowski, PhD, Ryszard Ólinski, Professor, Yu-Wei Cheng, PhD, Mikkael A. Sekeres, MD MS, Mingjiang Xu, MDPhD, Jaroslaw P. Maciejewski, PhD MD FACP

Blood (2017) 130 (Supplement 1): 1668.

https://doi.org/10.1182/blood.V130.Suppl_1.1668.1668

Published: 2017

Journal Articles

De Novo DNA Methylation Is Associated with Granulopoiesis and Megakaryopoiesis but Not Erythropoiesis

Jens Lichtenberg, PhD, Elisabeth F. Heuston, PhD, Stacie M. Anderson, NIH Intramural Sequencing Center, Cheryl A. Keller, PhD, Ross C. Hardison, PhD, David M. Bodine, PhD

Blood (2016) 128 (22): 3868.

https://doi.org/10.1182/blood.V128.22.3868.3868

Published: 2016

Journal Articles

Association Analysis Between Oncogenic Genes and the Efficacy of Demethylation Drug

Bianhong Wang

Blood (2016) 128 (22): 5255.

https://doi.org/10.1182/blood.V128.22.5255.5255

Published: 2016

Journal Articles

Tet2 Deficiency Leads to an Increased Inflammatory Phenotype in Murine Macrophages

Alyssa Cull, MSc, Brooke Snetsinger, MSc, Michael J. Rauh, MD PhD

Blood (2016) 128 (22): 708.

https://doi.org/10.1182/blood.V128.22.708.708

Published: 2016

Journal Articles

Distinct Regulatory Networks Govern Human Hematopoietic Stem Cell Across Development

Sasan Zandi, MDPhD, John E. Dick, PhD, Faiyaz Notta, Naoya Takayama

Blood (2015) 126 (23): 2375.

https://doi.org/10.1182/blood.V126.23.2375.2375

Published: 2015

Journal Articles

Multivariate Analysis Identifies Significant Correlations Between Baseline Biomarkers, DNA Demethylation and Clinical Responses in 122 Patients Treated in a Phase 1/2, Study of Guadecitabine (SGI-110), in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia (r/r AML)

Srikanth Gottipati, PhD, Shashank Rohatagi, PhD, Woonbok Chung, PhD, Pietro Taverna, PhD, Hagop M. Kantarjian, MD, Gail J. Roboz, MD, Patricia L. Kropf, MD, Mohammad Azab, MD, Jean-Pierre Issa, MD

Blood (2015) 126 (23): 2594.

https://doi.org/10.1182/blood.V126.23.2594.2594

Published: 2015

Journal Articles

Combination Treatment of AML Cells with Dnmt and HDAC Inhibitors: Synergistic Target Gene Downregulation Associated with Gene Body Demethylation

Nadja Blagitko-Dorfs, Pascal Schlosser, Dietmar Pfeifer, Michael Lübbert

Blood (2015) 126 (23): 2432.

https://doi.org/10.1182/blood.V126.23.2432.2432

Published: 2015

Journal Articles

GFI1 Snag Domain Methylation Directs LSD1 Recruitment to Control Transcription and Cell Fate Determination in Hematopoiesis

Matthew E Velinder, BS, Jason Singer, PhD, Jessica Meznarich, MD, Emily R Theisen, PhD, James Fulcher, BS, Christopher Tracy, PhD, Sarah Franklin, PhD, Sunil Sharma, MD, Michael E Engel, MD PhD

Blood (2015) 126 (23): 46.

https://doi.org/10.1182/blood.V126.23.46.46

Published: 2015

Journal Articles

Reactivation of the X-Chromosome Genes within PV Clone

Soo Jin Kim, MS, Jaroslav Jelinek, MD PhD, Jean-Pierre J Issa, MD, Josef T. Prchal, MD, Sabina Swierczek, PhD

Blood (2015) 126 (23): 4086.

https://doi.org/10.1182/blood.V126.23.4086.4086

Published: 2015

Journal Articles

Inflammaging-Associated Metabolic Alterations Foster Development of the MDS Genotype

Sheng Wei, MD, Erika Adriana Eksioglu, PhD MS, Xianghong Chen, PhD, Thomas Cluzeau, MDPhD, Ashley Basiorka, Alexis Burnette, Max Wei, Kathy L McGraw, PhD, Eric Padron, MD, Alan F. List, MD

Blood (2015) 126 (23): 144.

https://doi.org/10.1182/blood.V126.23.144.144

Published: 2015

Journal Articles

Histone deacetylase inhibition regulates inflammation and enhances Tregs after allogeneic hematopoietic cell transplantation in humans

Sung Won Choi, Erin Gatza, Guoqing Hou, Yaping Sun, Joel Whitfield, Yeohan Song, Katherine Oravecz-Wilson, Isao Tawara, Charles A. Dinarello, Pavan Reddy

Blood (2015) 125 (5): 815–819.

https://doi.org/10.1182/blood-2014-10-605238

Published: 2015

Includes: Supplemental data

Journal Articles

Molecular Background of BCP-ALL Cases with an Early Switch to Monocytic Lineage

Karel Fier, Lucie Slámová, Alena Dobiáová, Júlia Starková, Eva Froňková, Markéta Aliová, Kamila Polgárová, Maria E Figueroa, Tomá Kalina, Jan Zuna, Jan Trka, Jan Starý, Ondřej Hruák, Ester Mejstříková

Blood (2014) 124 (21): 3562.

https://doi.org/10.1182/blood.V124.21.3562.3562

Published: 2014

Journal Articles

PDGFR-Mediated Cytomegalovirus Infection of Megakaryocytes Induces Thrombocytopenia Via Demethylation of AML1 and IEX-1 in the TPO/c-Mpl Signaling Pathway Following Allo-HSCT

Xiao-Hui Zhang, MD, PhD, Feng Fei-er, Qian-ming Wang, Xiao-lu Zhu, Lan-ping Xu, Xiao Jun Huang

Blood (2014) 124 (21): 3937.

https://doi.org/10.1182/blood.V124.21.3937.3937

Published: 2014

NARROW

Novel CD4 + CD8 + Umbilical Cord Blood Regulatory T Cells

Lessons from Nature: A Novel Class of TET Inhibitors for TET2 Mutant Associated Diseases

Polycomb Group Proteins Recruit TET1 to Remove Aberrant DNA Methylation in Murine Embryonic Stem Cells

Pharmacologic LSD1 Inhibition Preserves Human Granulocytic While Expanding Monocytic Progenitors

Epigenetic Control of Foxp3, CAMTA1 and FUT7 Genes in Human Regulatory T Cells

Single-Cell Methylome and Transcriptome High-Resolution Maps Define the Effects of Epigenetic Modifiers on the Landscape of Hematopoietic Differentiation

Acute Deletion of Tet2 or Tet3 Transiently Dysregulate Murine Erythropoiesis

TET2 and MSH6: A Novel Role for MMR in the Pathogenesis of Myeloid Malignancies

De Novo DNA Methylation Is Associated with Granulopoiesis and Megakaryopoiesis but Not Erythropoiesis

Association Analysis Between Oncogenic Genes and the Efficacy of Demethylation Drug

Tet2 Deficiency Leads to an Increased Inflammatory Phenotype in Murine Macrophages

Distinct Regulatory Networks Govern Human Hematopoietic Stem Cell Across Development

Multivariate Analysis Identifies Significant Correlations Between Baseline Biomarkers, DNA Demethylation and Clinical Responses in 122 Patients Treated in a Phase 1/2, Study of Guadecitabine (SGI-110), in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia (r/r AML)

Combination Treatment of AML Cells with Dnmt and HDAC Inhibitors: Synergistic Target Gene Downregulation Associated with Gene Body Demethylation

GFI1 Snag Domain Methylation Directs LSD1 Recruitment to Control Transcription and Cell Fate Determination in Hematopoiesis

Reactivation of the X-Chromosome Genes within PV Clone

Inflammaging-Associated Metabolic Alterations Foster Development of the MDS Genotype

Histone deacetylase inhibition regulates inflammation and enhances Tregs after allogeneic hematopoietic cell transplantation in humans

Molecular Background of BCP-ALL Cases with an Early Switch to Monocytic Lineage

PDGFR-Mediated Cytomegalovirus Infection of Megakaryocytes Induces Thrombocytopenia Via Demethylation of AML1 and IEX-1 in the TPO/c-Mpl Signaling Pathway Following Allo-HSCT

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American Society of Hematology

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American Society of Hematology

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