Page 1 | Search Results | Blood | American Society of Hematology

1-20 of 180

Sort by

Sort Order Select

Journal Articles

Functional Evaluation and Mechanism Study of Kel As an Oncogenic Driver in Acute Erythroleukemia

Hui Jin, Jianyong Li, MD, Zijuan Wu, Handong Sun, Wenjie Liu, MD, Yanfeng Liu, PhD, Ming Hong, MD PhD, Sixuan Qian, Wei Xu, MD PhD

Blood (2019) 134 (Supplement_1): 1246.

https://doi.org/10.1182/blood-2019-124607

Published: 2019

Journal Articles

Depletion of the Long Non-Coding RNA MALAT1 primes Chronic Myelomonocytic Leukemia (CMML) for Differentiation Therapy with All- Trans retinoic Acid (ATRA) through the Transcription Factor CREB

Blood (2019) 134 (Supplement_1): 1692.

https://doi.org/10.1182/blood-2019-128573

Published: 2019

Journal Articles

Cyclic-AMP Is an Actionable Novel Regulator of PD-L1 Expression in Untransformed Lymphocytes and Diffuse Large B Cell Lymphomas

Binu Sasi, PhD, Zhijun Qiu, PhD, Shoulei Jiang, PhD, An-Ping Lin, MD, Ricardo Aguiar, MD PhD

Blood (2019) 134 (Supplement_1): 3962.

https://doi.org/10.1182/blood-2019-123155

Published: 2019

Journal Articles

CCS1477: A Novel Small Molecule Inhibitor of p300/CBP Bromodomain for the Treatment of Acute Myeloid Leukaemia and Multiple Myeloma

Nigel Brooks, PhD, Meera Raja, PhD, Barbara W Young, PhD, Gary J Spencer, PhD, Tim CP Somervaille, MD PhD, Neil A Pegg, PhD

Blood (2019) 134 (Supplement_1): 2560.

https://doi.org/10.1182/blood-2019-124707

Published: 2019

Journal Articles

Diffuse Large B Cell Lymphoma (DLBCL) Expresses ROR1 and a ROR1 Small Molecule Inhibitor (KAN0441571C) Induced Significant Apoptosis of Tumor Cells

Mohammad Hojjat-Farsangi, MSc,PhD, Amineh Ghaderi, MSc, AmirHossein Daneshmanesh, MD PhD, Jemina Lehto, MSc, Ali Moshfegh, MSc,PhD, Parviz Kokhaei, MSc,PhD, Jan Vågberg, MSc,PhD, Elisabeth Olsson, MSc,PhD, Charlotta Löfberg, MSc,PhD, Charlotta Carina Norström, MSc,PhD, Johan Schultz, MSc,PhD, Martin Norin, MSc,PhD, Thomas Olin, MSc,PhD, Elias Drakos, MD PhD Prof., George Z. Rassidakis, MD PhD Prof., Anders Österborg, MD PhD, Håkan Mellstedt, MD PhD Prof.

Blood (2019) 134 (Supplement_1): 2565.

https://doi.org/10.1182/blood-2019-126801

Published: 2019

Journal Articles

P38α/JNK Signaling Restrains Erythropoiesis By Suppressing Ezh2-Mediated Epigenetic Silencing of Bim

Ping Hu, MD PhD, Angel Nebreda, PhD, Helmut Hanenberg, MD, Garrett Kinnebrew, MD, Mircea Ivan, MD PhD, Mervin C. Yoder, MD, Marie-Dominique Filippi, PhD, Hal E. Broxmeyer, PhD, Reuben Kapur, PhD

Blood (2018) 132 (Supplement 1): 3837.

https://doi.org/10.1182/blood-2018-99-117098

Published: 2018

Journal Articles

Prostaglandin E2 Stimulates CREB-Mediated Modification of Histone Variant Nucleosomes at Enhancers to Promote Hematopoietic Stem Cell Fate

Audrey Sporrij, MSc, Eva M. Fast, PhD, Brejnev Muhire, PhD, Margot Manning, BA, Marian Kalocsay, PhD, Robert E. Kingston, PhD, Michael Y. Tolstorukov, PhD, Leonard I. Zon, MD

Blood (2018) 132 (Supplement 1): 530.

https://doi.org/10.1182/blood-2018-99-115232

Published: 2018

Journal Articles

Targeting Both BET and Crebbp/EP300 Proteins with the Novel Dual Inhibitor NEO2734 Leads to More Preclinical Anti-Tumor Activity in Diffuse Large B Cell Lymphomathan with Single BET or Crebbp/EP300 Inhibitors

Filippo Spriano, Eugenio Gaudio, PhD, Chiara Tarantelli, PhD, Gaetanina Golino, Luciano Cascione, PhD, Emanuele Zucca, Anastasios Stathis, MD, Francis J. Giles, MD FRCPI, FRCPath, Francesco Bertoni, MD

Blood (2018) 132 (Supplement 1): 4174.

https://doi.org/10.1182/blood-2018-99-114900

Published: 2018

Journal Articles

Pyrvinium Pamoate Overcomes Cabozantinib-Resistance of FLT3 -ITD AML Cells through Modulating the Mitochondria Functions and Signaling Pathways

Yu-Hsuan Fu, BS, Wen-Hui Lu, MS, Pei-Qi Lan, MS, Chung-Yi Hu, PhD, Chien-Yuan Chen, MD, PhD, Da-Liang Ou, PhD, Hwei-Fang Tien, MD, PhD, Liang-In Lin, PhD

Blood (2018) 132 (Supplement 1): 4683.

https://doi.org/10.1182/blood-2018-99-118476

Published: 2018

Journal Articles

Therapeutic Disassembly of Leukemogenic Enhancer Complexes

Lauren Forbes, BS, MS, Krasnopolsky Isaac, BA, Gerard Minuesa Dinares, PhD, Michael G. Kharas, PhD, Alex Kentsis, MD PhD

Blood (2018) 132 (Supplement 1): 1352.

https://doi.org/10.1182/blood-2018-99-118807

Published: 2018

Journal Articles

G-CSF Signaling Counteracts TGF-β—PAI-1-Dependent Retention of Hematopoietic Stem Cells in the Niche

Takashi Yahata, PhD, Abd Aziz Ibrahim, PhD, Toshio Miyata, MD, PhD, Kiyoshi Ando, MD PhD

Blood (2017) 130 (Supplement 1): 1133.

https://doi.org/10.1182/blood.V130.Suppl_1.1133.1133

Published: 2017

Journal Articles

Aberrant HCK Survival Signaling By Mutated MYD88 Requires PAX5 in Waldenstrom's Macroglobulinemia and ABC DLBCL Cells

Xia Liu, MD, Jiaji Chen, BS, Manit Munshi, MS, Lian Xu, Nickolas Tsakmaklis, BA, Maria Demos, BS, Amanda Kofides, BS, Maria Luisa Guerrera, MD, Gloria Chan, MS, Christopher Patterson, MAcc, Joshua Gustine, Jorge J. Castillo, MD, Zachary Hunter, PhD, Steven P Treon, MDPhDFRCP, Guang Yang, PhD

Blood (2017) 130 (Supplement 1): 1199.

https://doi.org/10.1182/blood.V130.Suppl_1.1199.1199

Published: 2017

Journal Articles

Overexpression of BRD4 Is an Adverse Prognostic Factor in Acute Myeloid Leukemia

Hima Bansal, Steven Kornblau, MD, Qiu Yihua, Kevin R Coombes, Subbarayalu Panneerdoss, Anand Karnad, MD, Steven Weitman, MD PhD, Gail Tomlinson, MD PhD, Sanjay Bansal, Swami P. Iyer, MD

Blood (2017) 130 (Supplement 1): 3794.

https://doi.org/10.1182/blood.V130.Suppl_1.3794.3794

Published: 2017

Journal Articles

Examining the CREB Transcriptional Program in Erythropoiesis

Jacky Chung, PhD, Barry H. Paw, MD PhD, Harvey Lodish, PhD, Alireza Ghamari, PhD, Alan B. Cantor, MD, PhD

Blood (2017) 130 (Supplement 1): 933.

https://doi.org/10.1182/blood.V130.Suppl_1.933.933

Published: 2017

Journal Articles

Distinct Signaling Centers Define Stages of Human Erythropoiesis and Harbor Common Variations of Red Blood Cell Traits

Avik Choudhuri, PhD, Eirini Trompouki, PhD, Brian J Abraham, PhD, William Mallard, Min-Lee Yang, PhD, Alireza Ghamari, PhD, Kanen Hoi, Barbara Hummel, Sonja Boatman, Victoria Chan, Teresa V. Bowman, PhD, Song Yang, Yi Zhou, Sinichiro Takahashi, MD PhD, Alan B. Cantor, MD, PhD, Santhi Ganesh, MD, John Rinn, PhD, Richard A. Young, PhD, Leonard I. Zon, MD

Blood (2017) 130 (Supplement 1): 773.

https://doi.org/10.1182/blood.V130.Suppl_1.773.773

Published: 2017

Journal Articles

Glia Maturation Factor-Gamma Modulates M2 Activation of Macrophage Via Suppression of Mitochondria Function

Wulin Aerbajinai, MD PhD, Jie Liu, Chutima Kumkhaek, Jianqiong Zhu, Kyung Chin, Griffin Rodgers, MD

Blood (2017) 130 (Supplement 1): 998.

https://doi.org/10.1182/blood.V130.Suppl_1.998.998

Published: 2017

Journal Articles

First-in-Class Oral Small Molecule Against the Tyrosine Kinase ROR1 (KAN0439834) Induced Significant Apoptosis of Chronic Lymphocytic Leukemia Cells

Mohammad Hojjat-Farsangi, MSc, PhD Assist. Prof., Amir Hossein Daneshmanesh, MD PhD, Fariba Mozaffari, MSc, PhD, Lotta Hansson, Jan Vågberg, PhD, Styrbjörn Byström, PhD, Elisabeth Olsson, PhD, Charlotta Löfberg, PhD, Charlotta Carina Norström, PhD, Johan Schultz, PhD, Martin Norin, PhD, Thomas Olin, PhD, Anders Österborg, MD PhD Prof., Ali Moshfegh, PhD, Hakan Mellstedt, MD PhD Prof.

Blood (2017) 130 (Supplement 1): 4320.

https://doi.org/10.1182/blood.V130.Suppl_1.4320.4320

Published: 2017

Journal Articles

Dehydropeptidase 1 Promoted Survival and Cell Cycle Progression through Regulation of CREB and P53 Pathways in B-Cell ALL

Jia-Min Zhang, MD, Shu-Juan Wang, Wen-Yi Lu, MD, Jiao Zhou, MD, Jing Zhang, MD, Xiao-Jun Huang, MD, Kai-Yan Liu, Guorui Ruan

Blood (2017) 130 (Supplement 1): 2719.

https://doi.org/10.1182/blood.V130.Suppl_1.2719.2719

Published: 2017

Journal Articles

Dysregulation of Follistatin Promotes Leukemogenesis in Acute Myeloid Leukemia

Alex Bai-Liang He, PhD, Nelson Ka Lam Ng, BA, Chae Yin Cher, Alan WL To, Chunxiao Zhang, Stephen SY Lam, Anskar Leung, MD PhD

Blood (2017) 130 (Supplement 1): 4982.

https://doi.org/10.1182/blood.V130.Suppl_1.4982.4982

Published: 2017

Journal Articles

Distinct signaling programs control human hematopoietic stem cell survival and proliferation

David J. H. F. Knapp, Colin A. Hammond, Nima Aghaeepour, Paul H. Miller, Davide Pellacani, Philip A. Beer, Karen Sachs, Wenlian Qiao, WeiJia Wang, R. Keith Humphries, Guy Sauvageau, Peter W. Zandstra, Sean C. Bendall, Garry P. Nolan, Carl Hansen, Connie J. Eaves

Blood (2017) 129 (3): 307–318.

https://doi.org/10.1182/blood-2016-09-740654

Published: 2017

Includes: Supplemental data

NARROW

Functional Evaluation and Mechanism Study of Kel As an Oncogenic Driver in Acute Erythroleukemia

Depletion of the Long Non-Coding RNA MALAT1 primes Chronic Myelomonocytic Leukemia (CMML) for Differentiation Therapy with All- Trans retinoic Acid (ATRA) through the Transcription Factor CREB

Cyclic-AMP Is an Actionable Novel Regulator of PD-L1 Expression in Untransformed Lymphocytes and Diffuse Large B Cell Lymphomas

CCS1477: A Novel Small Molecule Inhibitor of p300/CBP Bromodomain for the Treatment of Acute Myeloid Leukaemia and Multiple Myeloma

Diffuse Large B Cell Lymphoma (DLBCL) Expresses ROR1 and a ROR1 Small Molecule Inhibitor (KAN0441571C) Induced Significant Apoptosis of Tumor Cells

P38α/JNK Signaling Restrains Erythropoiesis By Suppressing Ezh2-Mediated Epigenetic Silencing of Bim

Prostaglandin E2 Stimulates CREB-Mediated Modification of Histone Variant Nucleosomes at Enhancers to Promote Hematopoietic Stem Cell Fate

Targeting Both BET and Crebbp/EP300 Proteins with the Novel Dual Inhibitor NEO2734 Leads to More Preclinical Anti-Tumor Activity in Diffuse Large B Cell Lymphomathan with Single BET or Crebbp/EP300 Inhibitors

Pyrvinium Pamoate Overcomes Cabozantinib-Resistance of FLT3 -ITD AML Cells through Modulating the Mitochondria Functions and Signaling Pathways

Therapeutic Disassembly of Leukemogenic Enhancer Complexes

G-CSF Signaling Counteracts TGF-β—PAI-1-Dependent Retention of Hematopoietic Stem Cells in the Niche

Aberrant HCK Survival Signaling By Mutated MYD88 Requires PAX5 in Waldenstrom's Macroglobulinemia and ABC DLBCL Cells

Overexpression of BRD4 Is an Adverse Prognostic Factor in Acute Myeloid Leukemia

Examining the CREB Transcriptional Program in Erythropoiesis

Distinct Signaling Centers Define Stages of Human Erythropoiesis and Harbor Common Variations of Red Blood Cell Traits

Glia Maturation Factor-Gamma Modulates M2 Activation of Macrophage Via Suppression of Mitochondria Function

First-in-Class Oral Small Molecule Against the Tyrosine Kinase ROR1 (KAN0439834) Induced Significant Apoptosis of Chronic Lymphocytic Leukemia Cells

Dehydropeptidase 1 Promoted Survival and Cell Cycle Progression through Regulation of CREB and P53 Pathways in B-Cell ALL

Dysregulation of Follistatin Promotes Leukemogenesis in Acute Myeloid Leukemia

Distinct signaling programs control human hematopoietic stem cell survival and proliferation

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only