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Journal Articles

miR-15a/16-1 deletion in activated B cells promotes plasma cell and mature B-cell neoplasms

Blood (2021) 137 (14): 1905–1919.

https://doi.org/10.1182/blood.2020009088

Published: 2021

Includes: Supplemental data

Journal Articles

SYK Inhibitor Entospletinib in Combination with Obinutuzumab Demonstrates Efficacy in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL)

Adam S. Kittai, MD, Scott R Best, BS, Bria Thurlow, BSc, Basak Gokcora, Andrzej Stadnik, MPH, BS, Renee MacKinnon, Taylor Hashiguchi Rowland, BS, Daniel O. Persky, MD, Byung Park, PhD, Stephen E Spurgeon, MD, Alexey Danilov, MD PhD

Blood (2019) 134 (Supplement_1): 4295.

https://doi.org/10.1182/blood-2019-123586

Published: 2019

Journal Articles

Ifitm3 Is Essential for PI(3,4,5)P3-Dependent B-Cell Activation and Leukemogenesis

Jaewoong Lee, PhD, Gang Xiao, PhD, Kadriye Nehir Nehir Cosgun, PhD, Huimin Geng, PhD, Ning Ma, PhD, Lai N Chan, PhD, Kohei Kume, PhD, Matthew Nix, PhD, Zhengshan Chen, MD PhD, Chun-Wei David Chen, PhD, Jianjun Chen, PhD, Vishal Khairnar, PhD, Arun P. Wiita, MD PhD, Andrei Thomas-Tikhonenko, PhD, Michael Farzan, MD PhD, Michael S. Diamond, PhD, Jae U Jung, PhD, Nagarajan Vaidehi, PhD, Markus Müschen, MD PhD

Blood (2019) 134 (Supplement_1): 2782.

https://doi.org/10.1182/blood-2019-127615

Published: 2019

Journal Articles

Integration of Genetic, Transcriptomic, and Immune Profiles Reveals Genomically-Distinct Populations in Low-Grade Lymphomas

Keenan T. Hartert, PhD, Kerstin Wenzl, PhD, Jordan Krull, Michelle Manske, MS, BS, Vivekananda Sarangi, Melissa C Larson, Theodora Anagnostou, MD, Ellen D. McPhail, MD, Brian K. Link, MD, Stephen M Ansell, MD PhD, James R. Cerhan, MD PhD, Dragan Jevremovic, MD PhD, Anne J Novak, PhD

Blood (2019) 134 (Supplement_1): 2764.

https://doi.org/10.1182/blood-2019-128803

Published: 2019

Journal Articles

Secreted Factors Determine Resistance to Idelalisib in Marginal Zone Lymphoma Models of Resistance

Alberto J Arribas, Sara Napoli, Eugenio Gaudio, PhD, Luciano Cascione, PhD, Alessandra Di Veroli, Chiara Tarantelli, PhD, Filippo Spriano, Antonella Zucchetto, Francesca Maria Rossi, PhD, Andrea Rinaldi, Anastasios Stathis, MD, Georg Stuessi, MD, Valter Gattei, MD, Gabriele Cruciani, Emanuele Zucca, MD, Davide Rossi, MD PhD, Francesco Bertoni, MD

Blood (2019) 134 (Supplement_1): 2569.

https://doi.org/10.1182/blood-2019-124299

Published: 2019

Journal Articles

A Phase Ib, Open-Label, Randomized Study to Assess Safety and Preliminary Efficacy of Tafasitamab (MOR208) or Tafasitamab + Lenalidomide in Addition to R-CHOP in Patients with Newly Diagnosed Diffuse Large B-Cell Lymphoma: The First-Mind Trial

John M Burke, MD, Marc André, Bruce D. Cheson, MD, Johannes Duell, MD, Grzegorz Nowakowski, MD, Andreas Rosenwald, MD, Gilles A. Salles, MD PhD, Jeff P. Sharman, MD, Philipp Bernhard Staber, MD PhD, Marek Trněný, MD, Jason R. Westin, MD, Wolfram Brugger, Günter Fingerle-Rowson, MD PhD, Magdalena Klanova, Guido Würth, PhD, Lorenz Truemper, MD

Blood (2019) 134 (Supplement_1): 2877.

https://doi.org/10.1182/blood-2019-128021

Published: 2019

Journal Articles

Transcriptome Sequencing Demonstrates Unique Signature Associated with Durable Clinical Response to DC/AML Fusion Vaccine

Blood (2019) 134 (Supplement_1): 3832.

https://doi.org/10.1182/blood-2019-129451

Published: 2019

Journal Articles

CD47 Regulates Red Blood Cell Alloimmunization in Mice

Ryan Jajosky, MD, Connie Arthur, PhD, Jerry Allen, BS, Megan Fuller, BS, Patricia E Zerra, MD, Cheryl Maier, MD PhD, Sean R. Stowell, MD PhD

Blood (2019) 134 (Supplement_1): 100.

https://doi.org/10.1182/blood-2019-131598

Published: 2019

Journal Articles

Evaluation of the Oral SYK Inhibitor Fostamatinib in Patients after Allogeneic Transplantation for Chronic Graft-Versus-Host Disease

William C. McManigle, MD, Rachel A. DiCioccio, BS, Sarah Anand, MD, Zhiguo Li, PhD, Jonathan C Poe, PhD, Krista R. Nichols, RN, MSN, AOCNS, Amy N. Suthers, PhD, Wei Jia, MD PhD, Kelly Corbet, BS, Megan Covington, BS, Julia Lloyd-Cowden, BS, Richard D. Lopez, MD, Gwynn D. Long, MD, Mitchell E. Horwitz, MD, Cristina Gasparetto, MD, Anthony D. Sung, MD, Nelson J. Chao, MD, David A. Rizzieri, MD, Stefanie Sarantopoulos, MD PhD

Blood (2019) 134 (Supplement_1): 4521.

https://doi.org/10.1182/blood-2019-130742

Published: 2019

Journal Articles

PTBP1 Regulates Alternative Splicing of Apoptotic Protein: Implications in CLL and Ibrutinib Resistance

Huayuan Zhu, Xiaotong Li, Xinqi Zheng, Juejin Wang, Hanning Tang, Wei Xu, MD PhD, Jianyong Li, MD

Blood (2019) 134 (Supplement_1): 1290.

https://doi.org/10.1182/blood-2019-126945

Published: 2019

Journal Articles

First-in-Human Trial of Bcma-CD19 Compound CAR with Remarkable Donor-Specific Antibody Reduction

Fang Liu, MD PhD, Hongyu Zhang, MD PhD, Xiao Wang, MD PhD, Yisong Xiong, PhD, Yuanzhen Cao, Yi Su, MD, Hai Yi, MD PhD, Jia Feng, MD PhD, Wenli Zhang, MD, Yu Ma, Masayuki Wada, PhD, Yupo Ma, MD PhD

Blood (2019) 134 (Supplement_1): 38.

https://doi.org/10.1182/blood-2019-122964

Published: 2019

Journal Articles

Microrna-31 Regulates T-Cell Metabolism Via HIF1α and Promotes Effector Function

Yongxia Wu, PhD MD, Mengmeng Zhang, MD, David Bastian, Mohammed Hanief Sofi, PhD MS, Steven Douglas Schutt, BS, Hee-Jin Choi, PhD, Corey Mealer, Hung D Nguyen, PhD, Linlu Tian, Xue-Zhong Yu, MD MS

Blood (2019) 134 (Supplement_1): 623.

https://doi.org/10.1182/blood-2019-131587

Published: 2019

Journal Articles

IRF4 Is Reciprocally Dysregulated Via NF-Κb-Dependent Expression and Loss-of-Function Mutations in Multiple Myeloma

Yun Dai, MD, Yue Sun, MS, Shaji K. Kumar, MD, Wei Wu, MD, Fengyan Jin, MD PhD

Blood (2019) 134 (Supplement_1): 687.

https://doi.org/10.1182/blood-2019-132051

Published: 2019

Journal Articles

Activated CLL B Cells Variably Modulate microRNA-155 Levels in Naïve CD4 + T Cells, and the Direction and Magnitude of microRNA-155 Change Correlates with Th17 Levels and Clinical Course

Byeongho Jung, BS, Gerardo Ferrer, PhD, Pui Yan Chiu, Rukhsana Aslam, MD, Florencia Palacios, PhD, Barbara Sherry, PhD, Nicholas Chiorazzi, MD

Blood (2018) 132 (Supplement 1): 4402.

https://doi.org/10.1182/blood-2018-99-116505

Published: 2018

Journal Articles

Functional Analysis of HDAC11 in Plasma Cell Development and Multiple Myeloma Survival

AGM Mostofa, PhD, Allison Distler, Mark B. Meads, PhD, Eva Sahakian, PhD, John J. Powers, BS, Tuan Nguyen, Melissa Alsina, MD, Taiga Nishihori, MD, Rachid Baz, MD, Javier Pinilla Ibarz, MD, Eduardo Sotomayor, MD, Kenneth H. Shain, MD PhD, Jason B. Brayer, PhD MD

Blood (2018) 132 (Supplement 1): 3223.

https://doi.org/10.1182/blood-2018-99-119119

Published: 2018

Journal Articles

Tecfidera Modulates Activation of Malignant B-Cells: Correlative Analysis from a Phase 1 Clinical Trial in Patients with Chronic Lymphocytic Leukemia

Christina Wu, PhD, Emanuela M. Ghia, PhD, Fitzgerald Lao, Minya Pu, PhD, Karen Messer, PhD, Laura Z. Rassenti, PhD, Thomas J. Kipps, MD PhD, Dennis A. Carson, MD, Michael Y. Choi, MD

Blood (2018) 132 (Supplement 1): 3143.

https://doi.org/10.1182/blood-2018-99-119292

Published: 2018

Journal Articles

Single-Cell RNA-Sequencing of Peripheral Blood Mononuclear Cells Reveals Changes in Immune Cell Composition and Distinct Inflammatory Gene Expression Profiles during Idiopathic Multicentric Castleman Disease Flare

Ruth-Anne Langan, BA, Dustin Shilling, PhD, Michael Gonzalez, PhD, Charlly Kao, PhD, Hakon Hakonarson, MD PhD, Taku Kambayashi, MD PhD, David C Fajgenbaum, MD MBA, MSc

Blood (2018) 132 (Supplement 1): 2406.

https://doi.org/10.1182/blood-2018-99-110461

Published: 2018

Journal Articles

Novel Form of Alternative Splicing of NFKB1. Its Role in Polycythemia and Adaptation to High Altitude in Andean Aymara

Jihyun Song, PhD, Seonggyun Han, MS, Ricardo Amaru, MD, Teddy Quispe, Msc, Dongwook Kim, MS, Jacob E. Crawford, PhD, Josef Stehlik, MD, Rasmus Nielsen, PhD, Younghee Lee, PhD, Josef T. Prchal, MD

Blood (2018) 132 (Supplement 1): 2316.

https://doi.org/10.1182/blood-2018-99-117463

Published: 2018

Journal Articles

Most CD5 + B Lymphocytes Secrete IL-10 in Autoimmune Hemolytic Anemia/Evans Syndrome Patients

Limin Xing, Manjun Zhao, Hongli Zhu, Zonghong Shao, MD

Blood (2018) 132 (Supplement 1): 4887.

https://doi.org/10.1182/blood-2018-99-114395

Published: 2018

Journal Articles

The non-canonical NF-kappaB Signaling Pathway Contributes to the Expansion and Lymphomagenesis of CD40-activated B Cells

Laura Bernhardine Kuhn, MSc, Stefanie Zapf, Dr., Djermanovic Kristina, Dr., Daniel C. Strobl, BSc., Falk Weih, Dr., Helmut Blum, Dr., Oliver Weigert, MD, Lothar J. Strobl, Dr., Zimber-Strobl Ursula, Dr.

Blood (2018) 132 (Supplement 1): 1340.

https://doi.org/10.1182/blood-2018-99-113793

Published: 2018

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miR-15a/16-1 deletion in activated B cells promotes plasma cell and mature B-cell neoplasms

SYK Inhibitor Entospletinib in Combination with Obinutuzumab Demonstrates Efficacy in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL)

Ifitm3 Is Essential for PI(3,4,5)P3-Dependent B-Cell Activation and Leukemogenesis

Integration of Genetic, Transcriptomic, and Immune Profiles Reveals Genomically-Distinct Populations in Low-Grade Lymphomas

Secreted Factors Determine Resistance to Idelalisib in Marginal Zone Lymphoma Models of Resistance

A Phase Ib, Open-Label, Randomized Study to Assess Safety and Preliminary Efficacy of Tafasitamab (MOR208) or Tafasitamab + Lenalidomide in Addition to R-CHOP in Patients with Newly Diagnosed Diffuse Large B-Cell Lymphoma: The First-Mind Trial

Transcriptome Sequencing Demonstrates Unique Signature Associated with Durable Clinical Response to DC/AML Fusion Vaccine

CD47 Regulates Red Blood Cell Alloimmunization in Mice

Evaluation of the Oral SYK Inhibitor Fostamatinib in Patients after Allogeneic Transplantation for Chronic Graft-Versus-Host Disease

PTBP1 Regulates Alternative Splicing of Apoptotic Protein: Implications in CLL and Ibrutinib Resistance

First-in-Human Trial of Bcma-CD19 Compound CAR with Remarkable Donor-Specific Antibody Reduction

Microrna-31 Regulates T-Cell Metabolism Via HIF1α and Promotes Effector Function

IRF4 Is Reciprocally Dysregulated Via NF-Κb-Dependent Expression and Loss-of-Function Mutations in Multiple Myeloma

Activated CLL B Cells Variably Modulate microRNA-155 Levels in Naïve CD4 + T Cells, and the Direction and Magnitude of microRNA-155 Change Correlates with Th17 Levels and Clinical Course

Functional Analysis of HDAC11 in Plasma Cell Development and Multiple Myeloma Survival

Tecfidera Modulates Activation of Malignant B-Cells: Correlative Analysis from a Phase 1 Clinical Trial in Patients with Chronic Lymphocytic Leukemia

Single-Cell RNA-Sequencing of Peripheral Blood Mononuclear Cells Reveals Changes in Immune Cell Composition and Distinct Inflammatory Gene Expression Profiles during Idiopathic Multicentric Castleman Disease Flare

Novel Form of Alternative Splicing of NFKB1. Its Role in Polycythemia and Adaptation to High Altitude in Andean Aymara

Most CD5 + B Lymphocytes Secrete IL-10 in Autoimmune Hemolytic Anemia/Evans Syndrome Patients

The non-canonical NF-kappaB Signaling Pathway Contributes to the Expansion and Lymphomagenesis of CD40-activated B Cells

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