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Journal Articles

A Prospective Study of Clonal Evolution in Follicular Lymphoma: Circulating Tumor DNA Correlates with Overall Tumor Burden and Fluctuates over Time without Therapy

Blood (2021) 138 (Supplement 1): 1328.

https://doi.org/10.1182/blood-2021-151096

Published: 2021

Journal Articles

A CK1δ/CK1ε Regulated Metabolic Circuit Is a Therapeutic Vulnerability for Multiple Myeloma

Karen L Burger, PhD, Mark B. Meads, PhD, Anders Berglund, Paula S. Oliveira, Allison Distler, Praneeth Reddy Sudalagunta, PhD, Timothy Jacobson, Jamie Teer, PhD, Eric A. Welsh, PhD, Hongyue Dai, PhD, John M. Koomen, PhD, Alugubelli Raghunandan Reddy, Gabriel De Avila, Alexandre Tungesvik, MD, William Roush, PhD, Ariosto Siqueira Silva, PhD, Kenneth H. Shain, MD PhD, John Cleveland, PhD

Blood (2019) 134 (Supplement_1): 5537.

https://doi.org/10.1182/blood-2019-130830

Published: 2019

Journal Articles

Functional Analysis of HDAC11 in Plasma Cell Development and Multiple Myeloma Survival

AGM Mostofa, PhD, Allison Distler, Mark B. Meads, PhD, Eva Sahakian, PhD, John J. Powers, BS, Tuan Nguyen, Melissa Alsina, MD, Taiga Nishihori, MD, Rachid Baz, MD, Javier Pinilla Ibarz, MD, Eduardo Sotomayor, MD, Kenneth H. Shain, MD PhD, Jason B. Brayer, PhD MD

Blood (2018) 132 (Supplement 1): 3223.

https://doi.org/10.1182/blood-2018-99-119119

Published: 2018

Journal Articles

Identification of Target Pathways of Acquired IMiD and Proteasome Inhibitor Resistance in Multiple Myeloma

Mark B. Meads, PhD, Paula Oliveira, Bin Fang, Praneeth Sudalagunta, PhD, Maria D Coelho Siqueira Silva, MSc, Tuan Nguyen, Allison Distler, Salah-Eddin Komrokji, Aunshka Collins, Hongyue Dai, PhD, John M. Koomen, Ariosto Siqueira Silva, PhD, Kenneth H Shain, MD PhD

Blood (2017) 130 (Supplement 1): 4411.

https://doi.org/10.1182/blood.V130.Suppl_1.4411.4411

Published: 2017

Journal Articles

HDAC11 Is a Candidate Therapeutic Target in Multiple Myeloma

Jason B. Brayer, PhDMD, Allison Distler, Mark B. Meads, PhD, Eva Sahakian, PhD, John J. Powers, BS, Tuan Nguyen, Melissa Alsina, MD, Taiga Nishihori, MD, Rachid Baz, MD, Javier Pinilla-Ibarz, MD PhD, Eduardo Martin Sotomayor, MD, Ken H Shain, MD PhD

Blood (2017) 130 (Supplement 1): 1800.

https://doi.org/10.1182/blood.V130.Suppl_1.1800.1800

Published: 2017

Journal Articles

A CK1δ/CK1ε-to-β-Catenin Circuit Is a Therapeutic Vulnerability for Primary and Drug Resistant Multiple Myeloma

Karen L Burger, PhD, Mark B. Meads, PhD, Ariosto Siqueira Silva, PhD, Paula Oliveira, Tuan Nguyen, Allison Distler, Maria Coelho Siqueira Silva, Timothy Jacobson, Jamie Teer, PhD, Hongyue Dai, PhD, William Roush, PhD, John Cleveland, PhD, Kenneth H Shain, MD PhD

Blood (2017) 130 (Supplement 1): 591.

https://doi.org/10.1182/blood.V130.Suppl_1.591.591

Published: 2017

Journal Articles

Identification of Target Pathways Induced By the Multiple Myeloma Tumor Microenvironment Using Activity-Based Protein Profiling and Ex Vivo Protein Kinase Inhibitor Screening

Mark B Meads, PhD, Paula Oliveira, BS, Allison Distler, B.S., Maria Silva, M.Sc, Karen Burger, PhD, Bin Fang, PhD, Aunshka Collins, BS, John L. Cleveland, PhD, John M. Koomen, PhD, Ariosto Silva, PhD, Dmitri Rebatchouk, PhD, Kenneth H. Shain, MD PhD, William R. Roush, PhD

Blood (2016) 128 (22): 3288.

https://doi.org/10.1182/blood.V128.22.3288.3288

Published: 2016

Journal Articles

a Combination of Ex Vivo and Computational Models Predicts Clinical Response in MM Treatment Combinations of Proteasome Inhibitors, Imids, Nuclear Export Inhibitors and Alkylating Agents

Ariosto Silva, PhD, Maria Silva, M.Sc, Timothy Jacobson, B.S., Mark B Meads, PhD, Allison Distler, B.S., Aunshka Collins, BS, Chris Cubitt, PhD, Lia E Perez, MD, Rachid Baz, MD, Dmitri Rebatchouk, PhD, Robert Gatenby, MD, PhD, Kenneth H. Shain, MD PhD

Blood (2016) 128 (22): 3291.

https://doi.org/10.1182/blood.V128.22.3291.3291

Published: 2016

Journal Articles

A CK1δ/CK1ε-to-Wnt/β-Catenin Circuit Is a Therapeutic Vulnerability in Primary and Drug Resistant Multiple Myeloma

Karen L. Burger, PhD, Mark B Meads, PhD, Ariosto Silva, PhD, Allison Distler, B.S., Maria Coelho Siqueira Silva, Timothy Jacobson, B.S., Jamie K Teer, PhD, William R. Roush, PhD, Kenneth H. Shain, MD PhD, John L. Cleveland, PhD

Blood (2016) 128 (22): 2094.

https://doi.org/10.1182/blood.V128.22.2094.2094

Published: 2016

Journal Articles

A Multidisciplinary Model Predicts Clinical Response in Relapsed Multiple Myeloma

Kenneth H. Shain, MD PhD, Ariosto Silva, PhD, Mark B Meads, PhD, Allison Distler, B.S., Timothy Jacobson, B.S., Robert Gatenby, MD, PhD, Rachid Baz, Maria Silva, M.Sc, Dmitri Rebatchouk, PhD, Chris Cubitt, PhD

Blood (2015) 126 (23): 501.

https://doi.org/10.1182/blood.V126.23.501.501

Published: 2015

Journal Articles

A Novel Role for Histone Deacetylase 11 (HDAC11) in B Cell Lymphopoiesis and Plasma Cell Survival in Multiple Myeloma

Jason B. Brayer, MDPhD, Eva Sahakian, PhD, John Powers, M.S., Mark B Meads, PhD, Susan Deng, Allison Distler, Melissa Alsina, MD, Taiga Nishihori, MD, Rachid Baz, MD, Alejandro Villagra, PhD, Javier Pinilla-Ibarz, MD PhD, Eduardo M. Sotomayor, MD, Kenneth H. Shain, MD PhD

Blood (2014) 124 (21): 4715.

https://doi.org/10.1182/blood.V124.21.4715.4715

Published: 2014

Journal Articles

Histone Deacetylase 11 (HDAC11) As a Novel Transcriptional Regulator of C/EBP-β, in Immature Myeloid Cell to Myeloid Derived Suppressor Cell Transition

Jie Chen, MA, Eva Sahakian, PhD, John J. Powers, B.S., Maritza LienlafMoreno, BS, Limin Xing, PhD, Susan Deng, Allison Distler, Fengdong Cheng, MD, Alejandro Villagra, PhD, Pedro Horna, MD, Eduardo M. Sotomayor, MD, Javier Pinilla-Ibarz, MD PhD

Blood (2014) 124 (21): 225.

https://doi.org/10.1182/blood.V124.21.225.225

Published: 2014

Journal Articles

A Novel Role For Histone Deacetylase 11 (HDAC11) As a Regulator Of Neutrophil Function and Differentiation In Normal and Malignant Hematopoesis

Eva Sahakian, Ph.D, John Powers, B.S., Jie Chen, M.A., Allison Distler, B.S., Jennifer Rock-Klotz, B.S., Susan Deng, B.S., Sheng Wei, MD, Eduardo M. Sotomayor, MD, Javier Pinilla-Ibarz, M.D. Ph.D., Pedro Horna, M.D.

Blood (2013) 122 (21): 2267.

https://doi.org/10.1182/blood.V122.21.2267.2267

Published: 2013

Journal Articles

A Novel Role For Histone Deacetylase 11 (HDAC11) In Plasma Cell Differentation and Survival

Eva Sahakian, Ph.D, Jason B. Brayer, MD, PhD, John Powers, B.S., Mark Meads, PhD, Allison Distler, Susan Deng, Melissa Alsina, MD, Taiga Nishihori, MD, Rachid Baz, MD, Javier Pinilla-Ibarz, MD, PhD, Eduardo M. Sotomayor, MD, Kenneth Shain, MD, PhD

Blood (2013) 122 (21): 1907.

https://doi.org/10.1182/blood.V122.21.1907.1907

Published: 2013

Journal Articles

Histone Deacetylase 11 (HDAC11) Is a Novel Regulator In The Expansion Of MDSCs Via The Transcription Factor C/EBP-β

Jie Chen, M.A., John Powers, B.S., Jennifer Rock-Klotz, B.S., Susan Deng, B.S., Allison Distler, B.S., Fengdong Cheng, MD, Alejandro Villagra, PhD, Eduardo M. Sotomayor, MD, Eva Sahakian, Ph.D, Javier Pinilla-Ibarz, MD, PhD

Blood (2013) 122 (21): 4887.

https://doi.org/10.1182/blood.V122.21.4887.4887

Published: 2013

NARROW

A Prospective Study of Clonal Evolution in Follicular Lymphoma: Circulating Tumor DNA Correlates with Overall Tumor Burden and Fluctuates over Time without Therapy

A CK1δ/CK1ε Regulated Metabolic Circuit Is a Therapeutic Vulnerability for Multiple Myeloma

Functional Analysis of HDAC11 in Plasma Cell Development and Multiple Myeloma Survival

Identification of Target Pathways of Acquired IMiD and Proteasome Inhibitor Resistance in Multiple Myeloma

HDAC11 Is a Candidate Therapeutic Target in Multiple Myeloma

A CK1δ/CK1ε-to-β-Catenin Circuit Is a Therapeutic Vulnerability for Primary and Drug Resistant Multiple Myeloma

Identification of Target Pathways Induced By the Multiple Myeloma Tumor Microenvironment Using Activity-Based Protein Profiling and Ex Vivo Protein Kinase Inhibitor Screening

a Combination of Ex Vivo and Computational Models Predicts Clinical Response in MM Treatment Combinations of Proteasome Inhibitors, Imids, Nuclear Export Inhibitors and Alkylating Agents

A CK1δ/CK1ε-to-Wnt/β-Catenin Circuit Is a Therapeutic Vulnerability in Primary and Drug Resistant Multiple Myeloma

A Multidisciplinary Model Predicts Clinical Response in Relapsed Multiple Myeloma

A Novel Role for Histone Deacetylase 11 (HDAC11) in B Cell Lymphopoiesis and Plasma Cell Survival in Multiple Myeloma

Histone Deacetylase 11 (HDAC11) As a Novel Transcriptional Regulator of C/EBP-β, in Immature Myeloid Cell to Myeloid Derived Suppressor Cell Transition

A Novel Role For Histone Deacetylase 11 (HDAC11) As a Regulator Of Neutrophil Function and Differentiation In Normal and Malignant Hematopoesis

A Novel Role For Histone Deacetylase 11 (HDAC11) In Plasma Cell Differentation and Survival

Histone Deacetylase 11 (HDAC11) Is a Novel Regulator In The Expansion Of MDSCs Via The Transcription Factor C/EBP-β

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American Society of Hematology

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American Society of Hematology

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