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Journal Articles

Genomic analyses of PMBL reveal new drivers and mechanisms of sensitivity to PD-1 blockade

Bjoern Chapuy, Chip Stewart, Andrew J. Dunford, Jaegil Kim, Kirsty Wienand, Atanas Kamburov, Gabriel K. Griffin, Pei-Hsuan Chen, Ana Lako, Robert A. Redd, Claire M. Cote, Matthew D. Ducar, Aaron R. Thorner, Scott J. Rodig, Gad Getz, Margaret A. Shipp

Blood (2019) 134 (26): 2369–2382.

https://doi.org/10.1182/blood.2019002067

Published: 2019

Includes: Supplemental data

Journal Articles

Transcriptional Regulation of Hematopoietic Stem Cells in Aging and Myelodysplastic Syndrome Reveals DDIT3 As a Potential Driver of Transformation

Blood (2019) 134 (Supplement_1): 3764.

https://doi.org/10.1182/blood-2019-122686

Published: 2019

Journal Articles

CD20-TCB, a Novel T-Cell-Engaging Bispecific Antibody, Can be Safely Combined with the Anti-PD-L1 Antibody Atezolizumab in Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Martin Hutchings, MD PhD, Giuseppe Gritti, MD PhD, Anna Sureda, MD PhD, Maria Jose Terol, Martin JS Dyer, DPhil, Gloria Iacoboni, MD, William Townsend, MRCP,MDFRCPath, Marina Bacac, PhD, Ann-Marie E Bröske, PhD, Natalie Dimier, PhD, Cristiano Ferlini, MD, Abiraj Keelara, PhD, Angelika Lahr, PhD, Katharina Lechner, MD, Tom Moore, MBChB, Peter N Morcos, PharmD, Anesh Panchal, MSc, Martin Weisser, MD, Ciel De Vriendt

Blood (2019) 134 (Supplement_1): 2871.

https://doi.org/10.1182/blood-2019-123978

Published: 2019

Journal Articles

Characterization of Mechanisms of Acquired Venetoclax-Insensitivity in B-Cell Precursor Acute Lymphoblastic Leukemia

Alexandra Niedermayer, MSc, Stefanie Enzenmüller, PhD, Eugen Tausch, Stephan Stilgenbauer, MD, Felix Seyfried, MD, Klaus-Michael Debatin, MD, Lüder Hinrich Meyer, MD

Blood (2019) 134 (Supplement_1): 3954.

https://doi.org/10.1182/blood-2019-126582

Published: 2019

Journal Articles

Genome-Wide CRISPR Library Screening Identifies CDK6 As Genetic Vulnerability in Adult T-Cell Leukemia/Lymphoma

Takashi Ishio, Joji Shimono, Sarvesh Kumar, Yuquan Lin, Emmanuel Bachy, Michael N. Petrus, Yandan Yang, Michiyuki Maeda, Hideki Goto, Satoshi Hashino, Takanori Teshima, MD, Thomas A. Waldmann, MD, Louis Staudt, MD, Masao Nakagawa

Blood (2019) 134 (Supplement_1): 3781.

https://doi.org/10.1182/blood-2019-124670

Published: 2019

Journal Articles

The DIAL Study (Dual Immunomodulation in Aggressive Lymphoma): A Randomized Phase 2 Study of CDX-1127 (Varlilumab) in Combination with Nivolumab in Patients with Relapsed or Refractory Aggressive B-Cell Lymphomas (NCI 10089 / NCT03038672)

Jose C Villasboas, MD, Craig B. Reeder, MD, Han W. Tun, MD, Nancy L Bartlett, MD, Elad Sharon, MD MPH, Betsy Laplant, MS, Alex A Adjei, MD PhD, Justin Kline, MD, Francisco J. Hernandez-Ilizaliturri, MD, Farrukh T. Awan, MD, Sumana Devata, MD, Aleksandr Lazaryan, MDPhDMPH, Lawrence E Morris, MD, Stephen M Ansell, MD PhD, Catherine Diefenbach, MD

Blood (2019) 134 (Supplement_1): 1591.

https://doi.org/10.1182/blood-2019-130449

Published: 2019

Journal Articles

PD-L1 Expression in Patients with Primary Central Nervous System Diffuse Large B-Cell Lymphoma: Its Correlation with Serum Levels of Soluble Programmed Death-Ligand 1 (sPD-L1)

Inju Cho, MD PhD, Seok Jin Kim, MD PhD, Hansang Lee, MD, Young Hyeh Ko, MD

Blood (2019) 134 (Supplement_1): 1601.

https://doi.org/10.1182/blood-2019-123311

Published: 2019

Journal Articles

CD34+ Derived Microparticles Regulate Apoptosis in Normal and Acute Myeloid Leukemia Cells

Angeliki Xagorari, PhD, Sarantis Tsetsakos, Bsc, Zoi Katana, Konstantinos Krikonis, undergraduate student, Anastasia Kouvatsi, Katerina Chlichlia, Assistant Professor, Achilles Anagnostopoulos, Damianos Sotiropoulos, MD

Blood (2018) 132 (Supplement 1): 5090.

https://doi.org/10.1182/blood-2018-99-114425

Published: 2018

Journal Articles

Tislelizumab (BGB-A317) for Relapsed/Refractory Classical Hodgkin Lymphoma: Preliminary Efficacy and Safety Results from a Phase 2 Study

Yuqin Song, MD PhD, Quanli Gao, MD, Huilai Zhang, PhD, Lei Fan, MD PhD, Jianfeng Zhou, PhD, Dehui Zou, MD, Wei Li, MD, Haiyan Yang, PhD, Ting Liu, MD, Quanshun Wang, MD PhD, Fangfang Lv, MD, Yu Yang, MD, Haiyi Guo, MD, Liudi Yang, MD, Rebecca Elstrom, MD, Jane Huang, MD, William Novotny, MD, Vivian Wei, PhD, Jun Zhu, MD PhD

Blood (2018) 132 (Supplement 1): 682.

https://doi.org/10.1182/blood-2018-99-117848

Published: 2018

Journal Articles

Oncolytics Virus Replication Using Pelareorep (Reolysin) and Carfilzomib in Relapsed Myeloma Patients Increases PD-L1 Expression with Clinical Responses

Craig C Hofmeister, MDMPH, Douglas W. Sborov, MD MS, Domenico Viola, Ada Dona, Gerald J Nuovo, PhD, Don M. Benson, Jr., MD PhD, Sagar Lonial, MD, Jonathan L Kaufman, MD, Ajay K Nooka, MD MPH, Leonard Heffner, MD, Madhav V Dhodapkar, MD, Flavia Pichiorri, PhD

Blood (2018) 132 (Supplement 1): 2655.

https://doi.org/10.1182/blood-2018-99-113500

Published: 2018

Journal Articles

Expression of PD-L1 in Leukemic Progenitor Cells Defines NPM1 Mutated AML As a Potential Subgroup for PD1/PD-L1 Directed Immunotherapy

Jochen Greiner, Vanessa Schneider, Dr. rer. nat., Hubert Schrezenmeier, MD, Markus Wiesneth, MD, Lars Bullinger, MD, Hartmut Döhner, MD, Susanne Hofmann, MD, Marlies Götz

Blood (2018) 132 (Supplement 1): 2734.

https://doi.org/10.1182/blood-2018-99-111458

Published: 2018

Journal Articles

Voice of Cancer Patients (VoCP): Analysis of Patient Experiences and Use of Burton's Tyrosine Kinase (BTK) Inhibitors and Venetoclax in Hematological Malignancies

Sangeeta Aggarwal, MD, Alok Aggarwal, PhD, Jyoti Bhowmick, M.B.A., Rishi Sharma, B.Tech, Rahul Gond, Siddhant Kapoor, B.Tech, Sujeet Kumar, B.Tech

Blood (2018) 132 (Supplement 1): 3582.

https://doi.org/10.1182/blood-2018-99-119727

Published: 2018

Journal Articles

A Novel PU.1 - Caspase 8/cFLIP Axis in Neutrophil and Macrophage Differentiation of AML Cells

Magali Humbert, PhD, Mario P. Tschan, PhD, Aladin Haimovici, Bruce E. Torbett, PhD, Nicolas Niklaus, MSc, BSc

Blood (2018) 132 (Supplement 1): 1347.

https://doi.org/10.1182/blood-2018-99-112797

Published: 2018

Journal Articles

Measurement of Serum microRNAs in US Veterans with Monoclonal Gammopathy of Undetermined Significance

Weixin Wang, PhD, Youn K Shim, PhD, Joel E Michalek, PhD, Emily Barber, BS, Layla M Saleh, MD PhD, Byeong Yeob Choi, PhD, Chen-Pin Wang, PhD, Norma Ketchum, MS, Rene Costello, MT, Gerald E Marti, MD PhD, Robert Vogt, PhD, Ola Landgren, MD PhD, Katherine R. Calvo, MD PhD

Blood (2018) 132 (Supplement 1): 5576.

https://doi.org/10.1182/blood-2018-99-114821

Published: 2018

Journal Articles

Relationship between Bone Marrow PD-1 and PD-L1 Expression and the Presence of Osteolytic Bone Disease in Multiple Myeloma Patients

Federica Costa, MS, Marina Bolzoni, PhD, Rosanna Vescovini, PhD, Fabrizio Accardi, MD, Anna Benedetta Dalla Palma, MD, Federica De Luca, PhD, Valentina Marchica, MS, Denise Toscani, PhD, Emanuela Vicario, MS, Paola Storti, PhD, Franco Aversa, MD, Nicola Giuliani, MD PhD

Blood (2018) 132 (Supplement 1): 3183.

https://doi.org/10.1182/blood-2018-99-118200

Published: 2018

Journal Articles

Thrombocytopenia Is a Biomarker for Response in Patients Treated with Anti PD-1/Pdl-1 Therapy

Hussein Assi, MD, Sami Ibrahimi, MD, Michael Machiorlatti, Sara K. Vesely, PhD MPH, Adam S. Asch, MD

Blood (2018) 132 (Supplement 1): 1138.

https://doi.org/10.1182/blood-2018-99-117764

Published: 2018

Journal Articles

Lymphopenia As an Early Predictor of Immune Related Adverse Events

Amir Kamran, MD, Zach Otaibi, DO, Rupin Arun Shah, MBBS, Gene Finley, MD

Blood (2018) 132 (Supplement 1): 4958.

https://doi.org/10.1182/blood-2018-99-119918

Published: 2018

Journal Articles

Donor T Cells Maintain Myeloma-Immune Equilibrium after Autologous Stem Cell Transplantation and Concurrent Immunotherapy Promotes Cure

Simone A Minnie, David Smith, Kate H Gartlan, PhD, Thomas S Watkins, Kate A Markey, PhD MBBS, Camille Guillerey, PhD, Rachel D Kuns, BSc, Kelly R Locke, Antiopi Varelias, PhD, Ping Zhang, Nicholas Huntington, PhD, Marta Chesi, PhD, John J Miles, PhD, Mark J Smyth, PhD, Slavica Vuckovic, PhD, Geoffrey R Hill, MD PhD

Blood (2018) 132 (Supplement 1): 2031.

https://doi.org/10.1182/blood-2018-99-118058

Published: 2018

Journal Articles

TIGIT immune checkpoint blockade restores CD8 + T-cell immunity against multiple myeloma

Camille Guillerey, Heidi Harjunpää, Nadège Carrié, Sahar Kassem, Tricia Teo, Kim Miles, Sophie Krumeich, Marianne Weulersse, Marine Cuisinier, Kimberley Stannard, Yuan Yu, Simone A. Minnie, Geoffrey R. Hill, William C. Dougall, Hervé Avet-Loiseau, Michele W. L. Teng, Kyohei Nakamura, Ludovic Martinet, Mark J. Smyth

Blood (2018) 132 (16): 1689–1694.

https://doi.org/10.1182/blood-2018-01-825265

Published: 2018

Journal Articles

Immune Checkpoint Inhibitors Restore Function of Lesion Infiltrating T Lymphocytes in Langerhans Cell Histiocytosis

Rikhia Chakraborty, PhD BSc, MSc, Carl E. Allen, MD PhD, Amel Sengal, BS, Amos S. Gaikwad, PhD, Harshal Abhyankar, MS, Brooks Scull, Olive S. Eckstein, MD, Miriam Merad, MD, Kenneth L. McClain, MD PhD

Blood (2017) 130 (Supplement 1): 2280.

https://doi.org/10.1182/blood.V130.Suppl_1.2280.2280

Published: 2017

NARROW

Genomic analyses of PMBL reveal new drivers and mechanisms of sensitivity to PD-1 blockade

Transcriptional Regulation of Hematopoietic Stem Cells in Aging and Myelodysplastic Syndrome Reveals DDIT3 As a Potential Driver of Transformation

CD20-TCB, a Novel T-Cell-Engaging Bispecific Antibody, Can be Safely Combined with the Anti-PD-L1 Antibody Atezolizumab in Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Characterization of Mechanisms of Acquired Venetoclax-Insensitivity in B-Cell Precursor Acute Lymphoblastic Leukemia

Genome-Wide CRISPR Library Screening Identifies CDK6 As Genetic Vulnerability in Adult T-Cell Leukemia/Lymphoma

The DIAL Study (Dual Immunomodulation in Aggressive Lymphoma): A Randomized Phase 2 Study of CDX-1127 (Varlilumab) in Combination with Nivolumab in Patients with Relapsed or Refractory Aggressive B-Cell Lymphomas (NCI 10089 / NCT03038672)

PD-L1 Expression in Patients with Primary Central Nervous System Diffuse Large B-Cell Lymphoma: Its Correlation with Serum Levels of Soluble Programmed Death-Ligand 1 (sPD-L1)

CD34+ Derived Microparticles Regulate Apoptosis in Normal and Acute Myeloid Leukemia Cells

Tislelizumab (BGB-A317) for Relapsed/Refractory Classical Hodgkin Lymphoma: Preliminary Efficacy and Safety Results from a Phase 2 Study

Oncolytics Virus Replication Using Pelareorep (Reolysin) and Carfilzomib in Relapsed Myeloma Patients Increases PD-L1 Expression with Clinical Responses

Expression of PD-L1 in Leukemic Progenitor Cells Defines NPM1 Mutated AML As a Potential Subgroup for PD1/PD-L1 Directed Immunotherapy

Voice of Cancer Patients (VoCP): Analysis of Patient Experiences and Use of Burton's Tyrosine Kinase (BTK) Inhibitors and Venetoclax in Hematological Malignancies

A Novel PU.1 - Caspase 8/cFLIP Axis in Neutrophil and Macrophage Differentiation of AML Cells

Measurement of Serum microRNAs in US Veterans with Monoclonal Gammopathy of Undetermined Significance

Relationship between Bone Marrow PD-1 and PD-L1 Expression and the Presence of Osteolytic Bone Disease in Multiple Myeloma Patients

Thrombocytopenia Is a Biomarker for Response in Patients Treated with Anti PD-1/Pdl-1 Therapy

Lymphopenia As an Early Predictor of Immune Related Adverse Events

Donor T Cells Maintain Myeloma-Immune Equilibrium after Autologous Stem Cell Transplantation and Concurrent Immunotherapy Promotes Cure

TIGIT immune checkpoint blockade restores CD8 + T-cell immunity against multiple myeloma

Immune Checkpoint Inhibitors Restore Function of Lesion Infiltrating T Lymphocytes in Langerhans Cell Histiocytosis

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American Society of Hematology

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American Society of Hematology

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