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maria Teresa Bochicchio
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Journal Articles

Centralized MRD Assessment in Gimema AML1718 Trial, a Phase 2 Open-Label Study of Venetoclax Combined with Intensified FLAI Chemotherapy (V-FLAI) As Induction Therapy of Non Low-Risk AML

Paola Minetto, Fabio Guolo, Sara Rosellini, Alfonso Piciocchi, Giovanni Marconi, Ernesta Audisio, Giorgio Priolo, Cristina Papayannidis, Maurizio Martelli, Giovanni Marsili, Monica Bocchia, Francesco Lanza, Albana Lico, Fabio Ciceri, Matteo Giovanni Della Porta, Marco Frigeni, Luisa Giaccone, Germana Beltrami, Erika Borlenghi, Maria Chiara Di Chio, Carmine Selleri, Enrico Crea, Irene Urbino, Chiara Sartor, Clara Minotti, Valentina Arena, Jacopo Nanni, Giorgia Simonetti, Maria Teresa Bochicchio, Giuseppe Saglio, Adriano Venditti, Marco Vignetti, Paola Fazi, Elisabetta Tedone, Giovanni Martinelli, Roberto Massimo Lemoli
Journal: Blood
Blood (2024) 144 (Supplement 1): 1574.
https://doi.org/10.1182/blood-2024-198139
Published: 2024
Journal Articles

Survival Analysis of Gimema AML1718, a Safety Run-in and Phase 2 Open-Label Study of Venetoclax, Fludarabine, Idarubicin and Cytarabine (V-FLAI) in the Induction Therapy of Non Low-Risk Acute Myeloid Leukemia

Giovanni Marconi, Alfonso Piciocchi, Ernesta Audisio, Cristina Papayannidis, Fabio Guolo, Marco Cerrano, Valentina Arena, Saveria Capria, Michela Rondoni, Matteo Giovanni Della Porta, Germana Beltrami, Monica Bocchia, Albana Lico, Luisa Giaccone, Marianna Rossi, Catello Califano, Matteo Giovanni Carrabba, Chiara Cattaneo, Marco Frigeni, Maria Chiara Di Chio, Bianca Serio, Roberto Freilone, Antonio Curti, Paola Minetto, Giovanni Marsili, Clara Minotti, Beatrice Anna Zannetti, Francesca Cotugno, Jacopo Nanni, Giorgia Simonetti, Maria Teresa Bochicchio, Sara Rosellini, Elisabetta Tedone, Adriano Venditti, Roberto Massimo Lemoli, Marco Vignetti, Paola Fazi, Giovanni Martinelli
Journal: Blood
Blood (2024) 144 (Supplement 1): 2891.
https://doi.org/10.1182/blood-2024-207842
Published: 2024
Journal Articles

Centralized MRD Assessment at Early Timepoints in Gimema AML1718 Trial, a Phase 2 Open-Label Study of Venetoclax, Fludarabine, Idarubicin and Cytarabine (V-FLAI) in the Induction Therapy of Non Low-Risk AML

Paola Minetto, Fabio Guolo, Sara Rosellini, Alfonso Piciocchi, Giovanni Marconi, Ernesta Audisio, Giorgio Priolo, Cristina Papayannidis, Maurizio Martelli, Francesca Paola Paoloni, Monica Bocchia, Francesco Lanza, Albana Lico, Fabio Ciceri, Matteo Giovanni Della Porta, Marco Frigeni, Luisa Giaccone, Germana Beltrami, Erika Borlenghi, Maria Chiara Di Chio, Carmine Selleri, Enrico Crea, Irene Urbino, Chiara Sartor, Clara Minotti, Valentina Arena, Jacopo Nanni, Giorgia Simonetti, Maria Teresa Bochicchio, Giuseppe Saglio, Adriano Venditti, Marco Vignetti, Paola Fazi, Elisabetta Tedone, Giovanni Martinelli, Roberto M. Lemoli
Journal: Blood
Blood (2023) 142 (Supplement 1): 1567.
https://doi.org/10.1182/blood-2023-189777
Published: 2023
Journal Articles

Novel Mechanisms of Venetoclax Resistance in Acute Myeloid Leukemia Based on Genomic Rearrangements

Irene Zacheo, Anna Ferrari, Eugenio Fonzi, Maria Teresa Bochicchio, Giorgia Capirossi, Jacopo Nanni, Matteo Paganelli, Chiara Servilli, Lorenzo Ledda, Martina Ghetti, Mouna Jandoubi, Matteo Marchesini, Agnese Mattei, Giovanni Martinelli, Giovanni Marconi, Giorgia Simonetti
Journal: Blood
Blood (2023) 142 (Supplement 1): 4165.
https://doi.org/10.1182/blood-2023-189435
Published: 2023
Journal Articles

Final Analysis for the Primary End-Point of Gimema AML1718, a Safety Run-in and Phase 2 Open-Label Study of Venetoclax, Fludarabine, Idarubicin and Cytarabine (V-FLAI) in the Induction Therapy of Non Low-Risk Acute Myeloid Leukemia

Giovanni Marconi, Alfonso Piciocchi, Ernesta Audisio, Cristina Papayannidis, Fabio Guolo, Marco Cerrano, Valentina Arena, Capria Saveria, Michela Rondoni, Matteo Giovanni Della Porta, Geramana Beltrami, Monica Bocchia, Albana Lico, Luisa Giaccone, Marianna Rossi, Catello Califano, Matteo Giovanni Carrabba, Chiara Cattaneo, Marco Frigeni, Maria Chiara Di Chio, Bianca Serio, Roberto Freilone, Antonio Curti, Paola Minetto, Giovanni Marsili, Clara Minotti, Beatrice Zannetti, Francesca Cotugno, Jacopo Nanni, Giorgia Simonetti, Maria Teresa Bochicchio, Sara Rosellini, Elisabetta Tedone, Adriano Venditti, Roberto Massimo Lemoli, Marco Vignetti, Paola Fazi, Giovanni Martinelli
Journal: Blood
Blood (2023) 142 (Supplement 1): 1536.
https://doi.org/10.1182/blood-2023-184678
Published: 2023
Journal Articles

Pre-Existing Myeloid Subclones May Account for a Subset of Acute Myeloid Leukemias and Myelodysplastic Neoplasms in Patients with Pre-Existing or Contemporary Lymphoid Disorders

Agnese Mattei, Giovanni Marconi, Sonia Ronconi, Delia Cangini, Michela Ceccolini, Claudio Cerchione, Irene Zacheo, Maria Benedetta Giannini, Marianna Norata, Giovanni Martinelli, Anna Ferrari, Maria Teresa Bochicchio, Martina Ghetti, Matteo Marchesini, Giorgia Simonetti, Gerardo Musuraca, Davide Nappi
Journal: Blood
Blood (2023) 142 (Supplement 1): 1475.
https://doi.org/10.1182/blood-2023-186760
Published: 2023
Journal Articles

Preferential Use of Coagulation Pathways Differs between Classical Myeloproliferative Neoplasms: Results of Global Coagulation Assays with Respect to Clinical and Genetic Features

Alessandro Lucchesi, Roberta Napolitano, Maria Teresa Bochicchio, Giorgia Simonetti, Giorgia Micucci, Monica Poggiaspalla, Valeria Di Battista, Gerardo Musuraca, Giovanni Martinelli, Giulio Giordano, Flavia Foca, Lucia Catani, Mariasanta Napolitano
Journal: Blood
Blood (2022) 140 (Supplement 1): 12160–12161.
https://doi.org/10.1182/blood-2022-171095
Published: 2022
Journal Articles

Gimema ALL2418: Interim Analysis of a Phase Iia Study of Feasibility and Effectiveness of Inotuzumab Ozogamicin in Adult Patients with B-Cell Acute Lymphoblastic Leukemia with Positive Minimal Residual Disease before Any Hematopoietic Stem Cell Transplantation

Giovanni Marconi, Alfonso Piciocchi, Sabina Chiaretti, Cristina Papayannidis, Monia Lunghi, Prassede Salutari, Patrizia Zappasodi, Alessandro Rambaldi, Attilio Olivieri, Maurizio Cavallari, Stefano Soddu, Nicola S Fracchiolla, Federica Gigli, Chiara Cattaneo, Daniele Giovanni Mattei, Anna Candoni, Giovanni Grillo, Maria Chiara Abbenante, Ernesta Audisio, Massimiliano Bonifacio, Albana Lico, Roberto Massimo Lemoli, Paolo De Fabritiis, Felicetto Ferrara, Martina Rachele Marino, Monica Messina, Anna Ferrari, Valentina Robustelli, Jacopo Nanni, Irene Della Starza, Giorgia Simonetti, Maria Stefania De Propris, Maria Teresa Bochicchio, Marco Vignetti, Paola Fazi, Giovanni Martinelli
Journal: Blood
Blood (2022) 140 (Supplement 1): 6119–6121.
https://doi.org/10.1182/blood-2022-157937
Published: 2022
Journal Articles

Gimema AML1718 Part 1: Planned Interim Analysis of a Safety Run-in and Phase 2 Open-Label Study of Venetoclax, Fludarabine, Idarubicin and Cytarabine (V-FLAI) in the Induction Therapy of Non Low-Risk Acute Myeloid Leukemia

Giovanni Marconi, Alfonso Piciocchi, Ernesta Audisio, Giorgio Priolo, Cristina Papayannidis, Maurizio Martelli, Francesca Paoloni, Roberto Massimo Lemoli, Monica Bocchia, Francesco Lanza, Albana Lico, Fabio Ciceri, Matteo G. Della Porta, Marco Frigeni, Luisa Giaccone, Germana Beltrami, Erika Borlenghi, Maria Chiara Di Chio, Carmine Selleri, Enrico Crea, Irene Urbino, Chiara Sartor, Clara Minotti, Fabio Guolo, Edoardo La Sala, Jacopo Nanni, Giorgia Simonetti, Maria Teresa Bochicchio, Giuseppe Saglio, Adriano Venditti, Marco Vignetti, Paola Fazi, Giovanni Martinelli
Journal: Blood
Blood (2022) 140 (Supplement 1): 1705–1707.
https://doi.org/10.1182/blood-2022-157393
Published: 2022
Journal Articles

IDH1/2 Mutations Are Maintained in a Subset of Patients with Acute Myeloid Leukemia in Complete Remission and Do Not Correlate with Residual Disease

Giovanni Marconi, Lorenza Bandini, Agnese Patuelli, Chiara Sartor, Sarah Parisi, Jacopo Nanni, Gianluca Cristiano, Letizia Zannoni, Giorgia Simonetti, Maria Teresa Bochicchio, Emanuela Ottaviani, Giovanni Martinelli, Stefania Paolini, Cristina Papayannidis, Michele Cavo, Antonio Curti
Journal: Blood
Blood (2021) 138 (Supplement 1): 4446.
https://doi.org/10.1182/blood-2021-149450
Published: 2021
Journal Articles

The Prolonged Inhibition of Chk1/Chk2 Kinases Enhances Genetic Instability and Compromises the Efficacy of Chemotherapy Against Acute Lymphoblastic Leukemia Cells

Andrea Ghelli Luserna Di Rorà, PhD, Antonella Padella, PhD, Maria Chiara Fontana, PhD, Eugenio Fonzi, PhD, Anna Ferrari, PhD, Enrica Imbrogno, PhD, Martina Ghetti, PhD, Roberta Napolitano, PhD, Maria Teresa Bochicchio, Giovanni Martinelli, MD, Giorgia Simonetti, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5047.
https://doi.org/10.1182/blood-2019-129964
Published: 2019
Journal Articles

A Comparison of Droplet Digital PCR and RT-qPCR for BCR-ABL1 Monitoring in Chronic Myeloid Leukemia

Carmen Fava, Paola Berchialla, PhD, Jessica Petiti, PhD, Maria Teresa Bochicchio, Barbara Izzo, PhD, Emilia Giugliano, Emanuela Ottaviani, Santa Errichiello, PhD, Giovanna Rege Cambrin, MD PhD, Claudia Venturi, Luigiana Luciano, Filomena Daraio, Daniele Calistri, Alessandro Martino, Giuseppe Saglio, MD, Giovanni Martinelli, MD, Fabrizio Pane, MD, Daniela Cilloni, MD PhD, Enrico Marco Gottardi
Journal: Blood
Blood (2019) 134 (Supplement_1): 2092.
https://doi.org/10.1182/blood-2019-125614
Published: 2019
Journal Articles

Negative Prognostic Relevance of a Specific 3-Gene Cluster in Myelodysplastic Syndromes during Azacitidine and Lenalidomide Therapy

Matilde Y Follo, PhD, Andrea Pellagatti, PhD, Richard N Armstrong, PhD, Stefano Ratti, MD, Sara Mongiorgi, PhD, Annalisa Astolfi, PhD, Valentina Indio, PhD, Maria Teresa Bochicchio, Cristina Clissa, MD PhD, Domenico Russo, MD, Marco Gobbi, MD, Sarah Parisi, Miriam Fogli, PhD, Giovanni Martinelli, Andrea Pession, MD, Michele Cavo, MD, Lucia Manzoli, MD, Lucio Cocco, MD, Jacqueline Boultwood, PhD, Carlo Finelli, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4347.
https://doi.org/10.1182/blood-2018-99-112062
Published: 2018
Journal Articles

Mitoxantrone, Etoposide and Cytarabine (MEC) Can Induce Deep Complete Remission and Is an Effective Bridge Therapy to Allotransplantation (SCT) in Refractory/Relapsed Acute Myeloid Leukemia (AML) Patients

Giovanni Marconi, Annalisa Talami, Maria Chiara Abbenante, Stefania Paolini, MD PhD, Chiara Sartor, Sarah Parisi, Stefano de Polo, Jacopo Nanni, MD, Luca Bertamini, MD, Simone Ragaini, Matteo Olivi, Maria Chiara Fontana, MSc, Maria Teresa Bochicchio, Emanuela Ottaviani, Carmen Baldazzi, Nicoletta Testoni, BSc, Giovanni Martinelli, Michele Cavo, MD, Cristina Papayannidis, Antonio Curti
Journal: Blood
Blood (2018) 132 (Supplement 1): 4036.
https://doi.org/10.1182/blood-2018-99-113036
Published: 2018
Journal Articles

Biology of Acute Myeloid Leukemia (AML) with Monosomy of Chromosome 7 or Loss of 7q. a Study on 487 Patients Analyzed By Gene Expression Profile (GEP), Single Nucleotide Polymorphism (SNP) Arrays and Metabolomics

Maria Chiara Fontana, MSc, Matteo Olivi, Giovanni Marconi, Mariachiara Abbenante, MD, Eugenio Fonzi, PhD, Stefania Paolini, MD PhD, Chiara Sartor, Sarah Parisi, Samantha Bruno, Martina Pazzaglia, Stefano De Polo, Jacopo Nanni, MD, Luca Bertamini, MD, Simone Ragaini, Annalisa Talami, Maria Teresa Bochicchio, Emanuela Ottaviani, Anna Ferrari, PhD, Carmen Baldazzi, Nicoletta Testoni, BSc, Torsten Haferlach, MD, Robert Kralovics, PhD, Jelena D. Milosevic Feenstra, PhD, Simona Soverini, PhD, Giovanni Martinelli, Antonio Curti, Michele Cavo, MD, Cristina Papayannidis, Giorgia Simonetti, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2748.
https://doi.org/10.1182/blood-2018-99-118183
Published: 2018
Journal Articles

First-Line Dasatinib in BCR-ABL1+ Chronic Myeloid Leukemia in Early Chronic Phase: A Gimema Prospective Multicentric Observational Study

Fausto Castagnetti, MD PhD, Gabriele Gugliotta, MD PhD, Massimo Breccia, MD PhD, Federica Sorà, MD, Alessandra Iurlo, MD PhD, Antonella Gozzini, MD, Anna Rita Scortechini, MD, Luigia Luciano, MD, Fabio Stagno, MD PhD, Alessandra Malato, MD, Elisabetta Abruzzese, MD, Monica Crugnola, MD, Patrizia Pregno, MD, Giorgina Specchia, MD, Pellegrino Musto, MD, Nicola Cascavilla, MD, Mario Tiribelli, MD, Massimiliano Bonifacio, MD, Piero Galieni, MD, Fausto Palmieri, MD, Simona Soverini, PhD, Maria Teresa Bochicchio, Simona Sica, MD, Robin Foà, MD, Michele Cavo, MD, Giovanni Martinelli, MD, Giuseppe Saglio, MD PhD, Fabrizio Pane, MD, Michele Baccarani, MD, Gianantonio Rosti, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1604.
https://doi.org/10.1182/blood.V130.Suppl_1.1604.1604
Published: 2017
Journal Articles

An Italian Multicentre Study Using Different Digital PCR Instruments on BCR-ABL1 Positive Patients at Different Levels of CML Disease

Filomena Daraio, PhD, Emilia Giugliano, Carmen Fava, MD PhD, Roberta Lorenzatti, Dr., Marta Varotto, Dr., Davide Barberio, Dr., Simona Bernardi, PhD, Barbara Izzo, PhD, Santa Errichiello, PhD, Maria Teresa Bochicchio, Claudia Venturi, Dr., Francesco Albano, MD, Giuseppe Saglio, MD PhD, Fabrizio Pane, MD, Giovanni Martinelli, MD, Giorgina Specchia, MD, Domenico Russo, MD, Enrico Marco Gottardi, Dr.
Journal: Blood
Blood (2017) 130 (Supplement 1): 4176.
https://doi.org/10.1182/blood.V130.Suppl_1.4176.4176
Published: 2017
Journal Articles

Alterations in Pathways Regulating Phosphatidil Inositol 3 Phosphate (PI3P) Produce Both Cell Proliferation and Therapy Resistance, and Define a Group of Patients with Poor Prognosis in Acute Myeloid Leukemia (AML)

Giovanni Marconi, MD, Cristina Papayannidis, MD PhD, Maria Chiara Fontana, Antonella Padella, Giorgia Simonetti, PhD, Marco Manfrini, PhD, Anna Ferrari, PhD, Eugenia Franchini, Stefania Paolini, MD, Sarah Parisi, MD, Chiara Sartor, Maria Chiara Abbenante, MD, Silvia Lo Monaco, Francesca Volpato, MD, Elena Tenti, Viviana Guadagnuolo, PhD, Margherita Perricone, PhD, Maria Teresa Bochicchio, Dr., Andrea Ghelli Luserna Di Rora, Carmen Baldazzi, PhD, Valentina Robustelli, Nicoletta Testoni, Simona Soverini, Emanuela Ottaviani, Giovanni Martinelli, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1679.
https://doi.org/10.1182/blood.V128.22.1679.1679
Published: 2016
Journal Articles

Assessment of BCR-ABL1 Transcript Levels By Digital PCR (dPCR) in CML Patients who Achieved a Deep Molecular Response (DMR: MR 4.0 , MR 4.5 And MR 5.0 ) with Tkis May Improve the Detection of Minimal Residual Disease (MRD) and the Selection of Patients for Treatment Free Remission (TFR)

Bernardi Simona, Andrea Di Palma, Federica Cattina, MD PhD, Simone Perucca, PhD, Michele Malagola, MD PhD, Mario Tiribelli, MD, Erika Codarin, Maria Teresa Bochicchio, Dr., Giuseppina Ruggeri, Luca Franceschini, MD, Valeria Cancelli, MD, Fausto Castagnetti, MD, Simona Soverini, Miriam Fogli, Claudia Venturi, Dr., Serena Lavorgna, Chiara Pagani, MD, Cristina Skert, MD, Camilla Zanaglio, Alessandro Turra, Nicola Polverelli, Luigi Caimi, Giuseppe Rossi, MD, Maria Teresa Voso, MD, Gianantonio Rosti, MD, Giovanni Martinelli, MD Prof., Michele Baccarani, Domenico Russo, MD
Journal: Blood
Blood (2016) 128 (22): 3096.
https://doi.org/10.1182/blood.V128.22.3096.3096
Published: 2016
Journal Articles

One-Step Quantitative Molecular Approach for Detection of BCR/ABL1 Rearrangement and for Monitoring of Minimal Residual Disease in CML Patients: An Inter Laboratory Study

Filomena Daraio, PhD, Maria Teresa Bochicchio, Dr., Barbara Izzo, PhD Prof., Claudia Venturi, Dr., Santa Errichiello, PhD, Francesca Crasto, Dr., Giovanna Rege-Cambrin, MD, Roberta Lorenzatti, Dr., Carmen Fava, MD, Fausto Castagnetti, MD, Fabrizio Pane, MD Prof., Giovanni Martinelli, MD Prof., Giuseppe Saglio, MD Prof., Enrico Marco Gottardi, Dr.
Journal: Blood
Blood (2016) 128 (22): 5423.
https://doi.org/10.1182/blood.V128.22.5423.5423
Published: 2016