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Journal Articles

Deficit of Circulating CD19 + CD24 hi CD38 hi Regulatory B Cells in Severe Aplastic Anemia

Yoshitaka Zaimoku, MD PhD, Bhavisha A Patel, MD, Sachiko Kajigaya, PhD, Xingmin Feng, PhD, Lemlem Alemu, BS, Diego Quinones Raffo, MSc, Emma M. Groarke, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 1219.

https://doi.org/10.1182/blood-2019-127053

Published: 2019

Journal Articles

A Common HLA Allelic Mutation of exon1 in Leukocytes Defines Class I Alleles Responsible for Autoantigen Presentation of Acquired Aplastic Anemia

Hiroki Mizumaki, MD, Kazuyoshi Hosomichi, PhD, Tatsuya Imi, MD PhD, Noriaki Tsuji, MD, Tanabe Mikoto, MD, Dung Cao Tran, MD, Kohei Thi Hosokawa, MD PhD, Yoshitaka Zaimoku, MD PhD, Kohei Hosokawa, MD PhD, Takamasa Katagiri, PhD, Fumihiro Azuma, Atsushi Tajima, PhD, Shinji Nakao, MD PhD

Blood (2019) 134 (Supplement_1): 1215.

https://doi.org/10.1182/blood-2019-123266

Published: 2019

Journal Articles

Spectrum and Clinical Significance of HLA Class I Alleles and Their Somatic Mutations in Immune Aplastic Anemia

Yoshitaka Zaimoku, MD PhD, Sharon D. Adams, MT, CHS (ABHI), Bhavisha A Patel, MD, Audrey Ai Chin Lee, MS, CHT (ABHI), Sachiko Kajigaya, PhD, Xingmin Feng, PhD, Olga Rios, RN, Holly DiFebo, RN, Lemlem Alemu, BS, Diego Quinones Raffo, MSc, Emma M. Groarke, MD, Willy A. Flegel, MD, Neal S. Young, MD

Blood (2019) 134 (Supplement_1): 3738.

https://doi.org/10.1182/blood-2019-127359

Published: 2019

Journal Articles

Escape Hematopoiesis By HLA-B5401-Lacking Hematopoietic Stem Progenitor Cells in Male Patients with Acquired Aplastic Anemia

Kohei Hosokawa, MD PhD, Mahmoud Ibrahim Elbadry, MD, Hiroki Mizumaki, MD, Luis Espinoza, MD PhD, Noriharu Nakagawa, MD, Kazuhisa Chonabayashi, MD PhD, Yoshinori Yoshida, MD PhD, Takamasa Katagiri, PhD, Yoshitaka Zaimoku, MD PhD, Tatsuya Imi, MD, Nguyen Thi Mai Anh, MD, Yoichi Fujii, MD, Seishi Ogawa, MD PhD, Katsuto Takenaka, MD PhD, Koichi Akashi, MD PhD, Shinji Nakao, MD PhD

Blood (2018) 132 (Supplement 1): 3855.

https://doi.org/10.1182/blood-2018-99-113756

Published: 2018

Journal Articles

Novel Human Anti-HLA-Bw4 and B61 Monoclonal Antibodies Kill Malignant B Cells Via CDC/ADCC While Sparing Normal Peripheral Blood Cells

Hiroyuki Takamatsu, MD PhD, Tatsuhiko Ozawa, PhD, Yoshitaka Zaimoku, MD, Akinori Tsuji, MD, Ichiro Hanamura, MD PhD, Junya Kuroda, MD PhD, Hidenori Tanaka, BS, Shintaro Kawai, PhD, Hiroyuki Kishi, PhD, Shinji Nakao, MD PhD

Blood (2017) 130 (Supplement 1): 2069.

https://doi.org/10.1182/blood.V130.Suppl_1.2069.2069

Published: 2017

Journal Articles

Chromosome 6 Loss-of-Heterozygosity in Pre-Transplant Blood Samples of Patients with Severe Aplastic Anemia Is Associated with Lower Risk of Acute Graft- Versus -Host Disease

Shahinaz M Gadalla, MD PhD, Weiyin Zhou, MS, Tao Wang, PhD, Yoshitaka Zaimoku, MD, Shinji Nakao, MD PhD, Laurie Burdette, PhD, Amanda Willis, BS, Medhat Askar, MD PhD, Michael Haagenson, MS, Meredith Yeager, PhD, Youjin Wang, Stephen R. Spellman, Stephen J Chanock, MD, Stephanie J. Lee, MD PhD, Sharon A Savage, MD

Blood (2017) 130 (Supplement 1): 4479.

https://doi.org/10.1182/blood.V130.Suppl_1.4479.4479

Published: 2017

Journal Articles

Identification of T Cell Receptors Specific to Antigens Presented By HLA-B5401 on IPS Cell-Derived Hematopoietic Stem Cells in a Patient with Acquired Aplastic Anemia Carrying B5401-Lacking Leukocytes

Noriharu Nakagawa, MD, Mahmoud Ibrahim Elbadry, MD, Yoshiki Akatsuka, MD, Hiroshi Hamana, Kiyomi Shitaoka, Yoshinori Yoshida, MD PhD, Kazuhisa Chonabayashi, MD PhD, Tatsuya Imi, MD, Yoshitaka Zaimoku, MD, Katsuto Takenaka, Hiroshi Fujiwara, MD PhD, Hiroyuki Kishi, PhD, Shinji Nakao, MD PhD

Blood (2017) 130 (Supplement 1): 2458.

https://doi.org/10.1182/blood.V130.Suppl_1.2458.2458

Published: 2017

Journal Articles

Development of Novel Human Anti-HLA-Monoclonal Antibodies for Clinical Applications Using Peripheral Blood B Cells Derived from Anti-HLA Antibody-Positive Donors

Hiroyuki Takamatsu, MD PhD, Yoshitaka Zaimoku, MD, Tatsuhiko Ozawa, PhD, Shintaro Kawai, PhD, Hidenori Tanaka, Phar.B., Hiroyuki Kishi, PhD, Atsushi Muraguchi, MD PhD, Shinji Nakao, MD PhD

Blood (2016) 128 (22): 4723.

https://doi.org/10.1182/blood.V128.22.4723.4723

Published: 2016

Journal Articles

HLA Class I Allele-Lacking Hematopoietic Stem/Progenitor Cells Support Long-Term Clonal Hematopoiesis without Oncogenic Driver Mutations in Acquired Aplastic Anemia

Tatsuya Imi, MD, Takamasa Katagiri, Kazuyoshi Hosomichi, PhD, Noriharu Nakagawa, Yoshitaka Zaimoku, MD, Ken Ishiyama, MD PhD, Atsushi Tajima, PhD, Shinji Nakao, MD PhD

Blood (2016) 128 (22): 3894.

https://doi.org/10.1182/blood.V128.22.3894.3894

Published: 2016

Journal Articles

Identification of an HLA Class I Allele Closely Involved in the Pathogenesis of Acquired Aplastic Anemia

Yoshitaka Zaimoku, MD, Hiroyuki Takamatsu, MD PhD, Kazuyoshi Hosomichi, PhD, Tatsuhiko Ozawa, PhD, Noriharu Nakagawa, Tatsuya Imi, MD, Hiroyuki Kishi, PhD, Koichi Kashiwase, MD PhD, Shinji Nakao, MD PhD

Blood (2016) 128 (22): 729.

https://doi.org/10.1182/blood.V128.22.729.729

Published: 2016

Journal Articles

Evidence That T Cells Specific for Non-Hematopoietic Cells Trigger the Development of Acquired Aplastic Anemia

Tatsuya Imi, Hiroyuki Maruyama, MD, Takamasa Katagiri, PhD, Yoshitaka Zaimoku, MD, Kana Maruyama, MD, Noriharu Nakagawa, MD, Kohei Hosokawa, MDPhD, Ken Ishiyama, Hirohito Yamazaki, MD PhD, Koichi Kashiwase, MD PhD, Shinji Nakao, MD PhD

Blood (2015) 126 (23): 1168.

https://doi.org/10.1182/blood.V126.23.1168.1168

Published: 2015

Journal Articles

Auto-Reactive Glycosyl-Phosphatidyl-Inositol (GPI) Specific T Cells Are Present in Most Patients with Idiopathic Aplastic Anemia (IAA)

Lucia Gargiulo, PhD, Yoshitaka Zaimoku, MD, Barbara Scappini, MD, Hiroyuki Maruyama, MD, Rie Ohumi, Lucio Luzzatto, MD, Shinji Nakao, MD PhD, Rosario Notaro, MD

Blood (2015) 126 (23): 2409.

https://doi.org/10.1182/blood.V126.23.2409.2409

Published: 2015

Journal Articles

Generation of Ips Cell-Derived Hematopoietic Progenitor Cells from Patients with Acquired Aplastic Anemia Harboring Copy Number Neutral Loss of Heterozygosity of the Short Arm of Chromosome 6

Luis Espinoza, MD PhD, Yoshinori Yoshida, MD PhD, Kazuhisa Chonabayashi, MD PhD, Takamasa Katagiri, PhD, Yoshitaka Zaimoku, MD, Shinji Nakao, MD PhD

Blood (2015) 126 (23): 2415.

https://doi.org/10.1182/blood.V126.23.2415.2415

Published: 2015

Journal Articles

Evidence for a Common Immune Pathophysiology in Acquired Aplastic Anemia and Ulcerative Colitis

Noriharu Nakagawa, MD, Hiroyuki Maruyama, MD, Yoshitaka Zaimoku, MD, Kana Maruyama, MD, Chizuru Saito, MD, Takamasa Katagiri, PhD, Kohei Hosokawa, MD PhD, Ken Ishiyama, MD PhD, Hirohito Yamazaki, MD PhD, Shinji Nakao, MD PhD

Blood (2015) 126 (23): 2418.

https://doi.org/10.1182/blood.V126.23.2418.2418

Published: 2015

Journal Articles

Hematopoiesis in Patients with Acquired Aplastic Anemia Is Supported By a Limited Number of CXCR4(-) Cells at the Common Myeloid Progenitor Level

Takamasa Katagiri, PhD, Atsuo Kasada, MD, Kana Motomiya, MD, Yoshitaka Zaimoku, MD, An T. T. Dao, MD, Hiroyuki Maruyama, MD, Ken Ishiyama, MD, PhD, Shigeki Ohtake, MD PhD, Atsushi Hirao, MD, Shinji Nakao, MD PhD

Blood (2014) 124 (21): 4392.

https://doi.org/10.1182/blood.V124.21.4392.4392

Published: 2014

Journal Articles

Resistance of Hematopoietic Stem Cells Lacking the KIR Ligand to Autologous NK Cell Attacks in Patients with Acquired Aplastic Anemia

Hiroyuki Maruyama, MD, Luis J. Espinoza, MD PhD, Takamasa Katagiri, PhD, Yoshitaka Zaimoku, MD, Koichi Kashiwase, Hiroo Saji, Seishi Ogawa, MD PhD, Shinji Nakao, MD PhD

Blood (2014) 124 (21): 2939.

https://doi.org/10.1182/blood.V124.21.2939.2939

Published: 2014

Journal Articles

Evidence That HLA-B40:02 and HLA-Α31:01 Are Strongly Involved in the Presentation of Autoantigens to CTLs Responsible for the Development of Acquired Aplastic Anemia

Yoshitaka Zaimoku, MD, Hiroyuki Maruyama, MD, Kana Maruyama, MD, Takamasa Katagiri, PhD, An T. T. Dao, MD, Hiroyuki Takamatsu, MD PhD, Hirohito Yamazaki, MD PhD, Koichi Kashiwase, Shinji Nakao, MD PhD

Blood (2014) 124 (21): 2948.

https://doi.org/10.1182/blood.V124.21.2948.2948

Published: 2014

Journal Articles

A Profound Decrease in FoxP3 + Helios + CD4 + T Cells in a Subset of Patients with Acquired Aplastic Anemia and Pure Red Cell Aplasia: A Common Mechanism Underlying a Dependency on Cyclosporine

An T. T. Dao, MD, Kohei Hosokawa, MDPhD, Chiharu Sugimori, MD PhD, Luis J. Espinoza, MD PhD, Kana Maruyama, MD, Yoshitaka Zaimoku, MD, Hiroyuki Maruyama, MD, Takamasa Katagiri, PhD, Hirohito Yamazaki, MD PhD, Hiroyuki Takamatsu, MD PhD, Chizuru Saito, MD, Noriko Iwaki, MD, Shinji Nakao, MD PhD

Blood (2014) 124 (21): 4384.

https://doi.org/10.1182/blood.V124.21.4384.4384

Published: 2014

Journal Articles

Donor-Type Aplastic Anemia after Allogeneic Hematopoietic Stem Cell Transplantation: A Common Cause of Late Graft Failure in Patients with Complete Donor Chimerism

Kana Maruyama, MD, Hiroyuki Maruyama, MD, Yoshitaka Zaimoku, MD, An T. T. Dao, MD, Takamasa Katagiri, PhD, Hirohito Yamazaki, MD PhD, Shinji Nakao, MD PhD

Blood (2014) 124 (21): 2411.

https://doi.org/10.1182/blood.V124.21.2411.2411

Published: 2014

Journal Articles

Prevalence, Clone Size and Lineage Diversity Of HLA-A Allele-Lacking Leukocytes In Patients With Acquired Aplastic Anemia

Hiroyuki Maruyama, MD, Takamasa Katagiri, Ph.D., Yoshitaka Zaimoku, MD, Chizuru Saito, MD, Kohei Hosokawa, MD, PhD, Hirohito Yamazaki, MD, PhD, Seishi Ogawa, MD, PhD, Shinji Nakao, MD, PhD

Blood (2013) 122 (21): 2475.

https://doi.org/10.1182/blood.V122.21.2475.2475

Published: 2013

NARROW

Deficit of Circulating CD19 + CD24 hi CD38 hi Regulatory B Cells in Severe Aplastic Anemia

A Common HLA Allelic Mutation of exon1 in Leukocytes Defines Class I Alleles Responsible for Autoantigen Presentation of Acquired Aplastic Anemia

Spectrum and Clinical Significance of HLA Class I Alleles and Their Somatic Mutations in Immune Aplastic Anemia

Escape Hematopoiesis By HLA-B5401-Lacking Hematopoietic Stem Progenitor Cells in Male Patients with Acquired Aplastic Anemia

Novel Human Anti-HLA-Bw4 and B61 Monoclonal Antibodies Kill Malignant B Cells Via CDC/ADCC While Sparing Normal Peripheral Blood Cells

Chromosome 6 Loss-of-Heterozygosity in Pre-Transplant Blood Samples of Patients with Severe Aplastic Anemia Is Associated with Lower Risk of Acute Graft- Versus -Host Disease

Identification of T Cell Receptors Specific to Antigens Presented By HLA-B5401 on IPS Cell-Derived Hematopoietic Stem Cells in a Patient with Acquired Aplastic Anemia Carrying B5401-Lacking Leukocytes

Development of Novel Human Anti-HLA-Monoclonal Antibodies for Clinical Applications Using Peripheral Blood B Cells Derived from Anti-HLA Antibody-Positive Donors

HLA Class I Allele-Lacking Hematopoietic Stem/Progenitor Cells Support Long-Term Clonal Hematopoiesis without Oncogenic Driver Mutations in Acquired Aplastic Anemia

Identification of an HLA Class I Allele Closely Involved in the Pathogenesis of Acquired Aplastic Anemia

Evidence That T Cells Specific for Non-Hematopoietic Cells Trigger the Development of Acquired Aplastic Anemia

Auto-Reactive Glycosyl-Phosphatidyl-Inositol (GPI) Specific T Cells Are Present in Most Patients with Idiopathic Aplastic Anemia (IAA)

Generation of Ips Cell-Derived Hematopoietic Progenitor Cells from Patients with Acquired Aplastic Anemia Harboring Copy Number Neutral Loss of Heterozygosity of the Short Arm of Chromosome 6

Evidence for a Common Immune Pathophysiology in Acquired Aplastic Anemia and Ulcerative Colitis

Hematopoiesis in Patients with Acquired Aplastic Anemia Is Supported By a Limited Number of CXCR4(-) Cells at the Common Myeloid Progenitor Level

Resistance of Hematopoietic Stem Cells Lacking the KIR Ligand to Autologous NK Cell Attacks in Patients with Acquired Aplastic Anemia

Evidence That HLA-B40:02 and HLA-Α31:01 Are Strongly Involved in the Presentation of Autoantigens to CTLs Responsible for the Development of Acquired Aplastic Anemia

A Profound Decrease in FoxP3 + Helios + CD4 + T Cells in a Subset of Patients with Acquired Aplastic Anemia and Pure Red Cell Aplasia: A Common Mechanism Underlying a Dependency on Cyclosporine

Donor-Type Aplastic Anemia after Allogeneic Hematopoietic Stem Cell Transplantation: A Common Cause of Late Graft Failure in Patients with Complete Donor Chimerism

Prevalence, Clone Size and Lineage Diversity Of HLA-A Allele-Lacking Leukocytes In Patients With Acquired Aplastic Anemia

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American Society of Hematology

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American Society of Hematology

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