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Journal Articles

HDAC11 deficiency disrupts oncogene-induced hematopoiesis in myeloproliferative neoplasms

Lanzhu Yue, Vasundhara Sharma, Nathan P. Horvat, Afua A. Akuffo, Matthew S. Beatty, Cem Murdun, Christelle Colin, Julia M. R. Billington, William E. Goodheart, Eva Sahakian, Ling Zhang, John J. Powers, Narmin E. Amin, Que T. Lambert-Showers, Lancia N. Darville, Javier Pinilla-Ibarz, Gary W. Reuther, Kenneth L. Wright, Chiara Conti, Jennifer Y. Lee, Xiaozhang Zheng, Pui Yee Ng, Matthew W. Martin, C. Gary Marshall, John M. Koomen, Ross L. Levine, Amit Verma, H. Leighton Grimes, Eduardo M. Sotomayor, Zonghong Shao, Pearlie K. Epling-Burnette
Journal: Blood
Blood (2020) 135 (3): 191–207.
https://doi.org/10.1182/blood.2019895326
Published: 2020
Includes: Supplemental data
Journal Articles

Selective Targeting of Histone Deacetylase 11 Disables Metabolism of Myeloproliferative Neoplasms

Vasundhara Sharma, PhD, Lanzhu Yue, MD, Nathan P. Horvat, MDCandidate, Agni Christodoulidou, PhD, Afua Adutwumwa Akuffo, PhDCandidate, Mathew Beatty, PhD, Cem Murdun, MS, Julia Billington, PhDCandidate, William E Goodheart, MS, PhDCandidate, Eva Sahakian, PhD, Ling Zhang, MD, John J. Powers, BS, Narmin E. Amin, Que T. Lambert-Showers, Lancia Darville, PhD, Javier Pinilla Ibarz, MD PhD, Gary W. Reuther, Jennifer Lee, PhD, Xiaozhang Zheng, PhD, Pui Yee Ng, PhD, Mathew W. Martin, PhD, Gary C. Marshall, PhD, John M. Koomen, PhD, Ross L. Levine, MD, Amit Verma, MBBS, H. Leighton Grimes, PhD, Eduardo Sotomayor, MD, Zonghong Shao, MD, Kenneth Wright, PhD, Pearlie K. Epling-Burnette
Journal: Blood
Blood (2019) 134 (Supplement_1): 474.
https://doi.org/10.1182/blood-2019-127235
Published: 2019
Journal Articles

Targeting Insulin-like Growth Factor/Insulin Receptor Signaling to Overcome JAK2 Inhibitor Persistence in Myeloproliferative Neoplasms

Lucia Mazzacurati, Que T. Lambert, Gary W. Reuther, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2935.
https://doi.org/10.1182/blood.V130.Suppl_1.2935.2935
Published: 2017
Journal Articles

The Pan-PIM Inhibitor INCB053914 Displays Potent Synergy at Low Doses in Combination with Ruxolitinib in Pre-Clinical Models of MPNs

Lucia Mazzacurati, Que T. Lambert, Robert J. Collins, Holly K. Koblish, PhD, Bruce Ruggeri, Matthew C. Stubbs, Gary W. Reuther, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1661.
https://doi.org/10.1182/blood.V130.Suppl_1.1661.1661
Published: 2017
Journal Articles

Single Molecule Dual JAK2-BET Inhibition As an MPN Therapeutic

Que T. Lambert, Stuart W. Ember, Muhammad Ayaz, Harshani R. Lawrence, Norbert Berndt, Steven Gunawan, Nicholas J. Lawrence, Ernst Schönbrunn, Gary W. Reuther
Journal: Blood
Blood (2015) 126 (23): 2826.
https://doi.org/10.1182/blood.V126.23.2826.2826
Published: 2015
Journal Articles

Pims: Potential Therapeutic Targets for Myeloproliferative Neoplasms

Que T. Lambert, Anuradha Pradhan, Gary W. Reuther
Journal: Blood
Blood (2014) 124 (21): 4575.
https://doi.org/10.1182/blood.V124.21.4575.4575
Published: 2014
Journal Articles

Activation of JAK2-V617F by Heterodimeric Receptor Components.

Anuradha R. Pradhan, PhD, Que T. Lambert, Lori N. Griner, Gary W. Reuther
Journal: Blood
Blood (2009) 114 (22): 2955.
https://doi.org/10.1182/blood.V114.22.2955.2955
Published: 2009
Journal Articles

Treatment with the Heat Shock Protein (hsp) 90 Inhibitor17-Dimethylaminoethylamino-17-Demethoxygeldanamycin (DMAG) Abrogates the Levels and Activity of the Receptor Tyrosine Kinase TrkA in Acute Leukemia Cells.

Sandhya Kumaraswamy, PhD, Que T. Lambert, MS, Kathy Rocha, BS, Purva Bali, MS, Warren Fiskus, PhD, Maria Balasis, BS, Michael Pranpat, MS, Sandhya Boyapalle, PhD, Alison Hannah, MD, Gary W. Reuther, PhD, Kapil Bhalla, MD
Journal: Blood
Blood (2005) 106 (11): 4401.
https://doi.org/10.1182/blood.V106.11.4401.4401
Published: 2005
Journal Articles

Incidence of immune responses following 102 infusions of autoplex in 18 hemophilic patients with antibody to factor VIII

Y Laurian, JP Girma, T Lambert, D Meyer, MJ Larrieu
Journal: Blood
Blood (1984) 63 (2): 457–462.
https://doi.org/10.1182/blood.V63.2.457.457
Published: 1984