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Soheil Meshinchi, MD PhD
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Journal Articles

Novel CD33 Antibodies Unravel Localization, Biology, and Therapeutic Implications of CD33 Isoforms

Mohammed Gbadamosi, BS, Tiffany A. Hylkema, BS, Soheil Meshinchi, MD PhD, Jatinder K Lamba, M.Sc., PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 908.
https://doi.org/10.1182/blood-2019-122596
Published: 2019
Journal Articles

Discovery of Novel IL3RA (CD123) Isoforms By Long Read Transcriptomics, Heterogeneous Expression Among AML Patient Cohorts and the Implications for Anti-CD123 Therapeutics

Jason G Underwood, PhD BA, Jenny L. Smith, MSc, MD, Lindsey F. Call, B.A., Elizabeth Tseng, PhD, Tiffany A. Hylkema, BS, Rhonda E. Ries, MA, Amanda R. Leonti, MS, Jason E. Farrar, MD, Timothy Junius Triche, Jr., PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4658.
https://doi.org/10.1182/blood-2019-131508
Published: 2019
Journal Articles

Development and Performance of Risk Stratification Models for AML Patients Utilizing ELN-2017 Guidelines and Additional Prognostic Factors: A SWOG Report

Era L Pogosova-Agadjanyan, BS, Anna Moseley, M.S., Megan Othus, PhD, Frederick R. Appelbaum, MD, Thomas R. Chauncey, MD PhD, I-Ming L. Chen, DVM, MS, Harry P. Erba, MD PhD, John E. Godwin, MD, Isaac C. Jenkins, MS, Min Fang, MD PhD, Mike Huynh, Kenneth J Kopecky, Alan F. List, MD, Jasmine Naru, PhD, Jerald P. Radich, MD, Emily Stevens, MD PhD, Brooke E Willborg, BS, Cheryl L. Willman, MD, Brent L Wood, MD PhD, Qing Zhang, Soheil Meshinchi, MD PhD, Derek Stirewalt, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2691.
https://doi.org/10.1182/blood-2019-124529
Published: 2019
Journal Articles

CD117 Expression Is Associated with Cytogenetic and Molecular Profiles and Outcome in Pediatric Acute Myeloid Leukemia

Katherine Tarlock, MD, Lisa Eidenschink Brodersen, PhD, Todd A. Alonzo, PhD, Yi-Cheng Wang, Robert B. Gerbing, Laura Pardo, Fangyan Dai, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, Jessica A. Pollard, MD, Michael R. Loken, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2699.
https://doi.org/10.1182/blood-2019-127100
Published: 2019
Journal Articles

Structural Variants Involving MLLT10/AF10 Are Associated with Adverse Outcome in AML Regardless of the Partner Gene - a COG/Tpaml Study

Rhonda E. Ries, MA, Amanda R. Leonti, MS, Timothy Junius Triche, Jr., PhD, Robert B. Gerbing, Betsy A Hirsch, PhD, Susana C. Raimondi, PhD, Jenny L. Smith, MSc, MD, Todd M Cooper, DO, Jason E. Farrar, MD, Aniruddha J. Deshpande, E. Anders Kolb, MD, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, Todd A. Alonzo, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 461.
https://doi.org/10.1182/blood-2019-125943
Published: 2019
Journal Articles

Correlation of CD123 Expression Level with Disease Characteristics and Outcomes in Pediatric Acute Myeloid Leukemia: A Report from the Children's Oncology Group

Adam J. Lamble, MD, Lisa Eidenschink Brodersen, PhD, Todd A. Alonzo, PhD, Jim Wang, Robert B. Gerbing, Laura Pardo, Lillian Sung, MD PhD, Sarah K. Tasian, MD, Todd M Cooper, DO, E. Anders Kolb, MD, Richard Aplenc, MD PhD, Michael R. Loken, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 459.
https://doi.org/10.1182/blood-2019-124587
Published: 2019
Journal Articles

Myeloid-Lineage Enhancers Drive Oncogene Synergy and Represent a Novel Therapeutic Target in CSF3R-CEBPA Mutant AML

Theodore Braun, MD PhD, Cody Coblentz, Sarah A Carratt, PhD BS, Mariam Okhovat, PhD, Amy Foley, MEng., Zachary Schonrock, BS, Kimberly Nevonen, Rhonda E. Ries, MA, Shannon K. McWeeney, PhD, Claus Nerlov, PhD, Soheil Meshinchi, MD PhD, Lucia Carbone, PhD, Brian J. Druker, Julia E. Maxson, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 543.
https://doi.org/10.1182/blood-2019-124773
Published: 2019
Journal Articles

Sorafenib in Combination with Standard Chemotherapy for Children with High Allelic Ratio FLT3/ITD+ AML Improves Event-Free Survival and Reduces Relapse Risk: A Report from the Children's Oncology Group Protocol AAML1031

Jessica A. Pollard, MD, Todd A. Alonzo, PhD, Patrick A. Brown, MD, Robert B. Gerbing, Elizabeth Fox, MD, John Kim Choi, MD, Brian T. Fisher, DO, MSCE, Betsy A Hirsch, PhD, Samir Kahwash, MD, John E. Levine, MDMS, Michael R. Loken, PhD, Susana C. Raimondi, PhD, Katherine Tarlock, MD, Andrew C. Wood, MBCHB, Lillian Sung, MD PhD, Anders E. Kolb, MD, Alan S Gamis, MD MPH, Soheil Meshinchi, MD PhD, Richard Aplenc, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 292.
https://doi.org/10.1182/blood-2019-129557
Published: 2019
Journal Articles

Response to Sorafenib in FLT3 /ITD AML Is Depedent on Co-Occurring Mutational Profile

Katherine Tarlock, MD, Jessica A. Pollard, MD, Todd A. Alonzo, PhD, Robert B. Gerbing, Yi-Cheng Wang, Rhonda E. Ries, MA, Jenny L. Smith, MSc, MD, E. Anders Kolb, MD, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 119.
https://doi.org/10.1182/blood-2019-127569
Published: 2019
Journal Articles

Somatic Bzip Mutations of CEBPA Are Associated with Favorable Outcome Regardless of Presence As Single Vs. Double Mutation

Katherine Tarlock, MD, Todd A. Alonzo, PhD, Yi-Cheng Wang, Robert B. Gerbing, Rhonda E. Ries, MA, Tiffany A. Hylkema, BS, William G. Woods, MD, Todd M Cooper, DO, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 181.
https://doi.org/10.1182/blood-2019-126273
Published: 2019
Journal Articles

Mesothelin Targeting Bites for Pediatric AML: In Vivo Efficacy and Specificity

Anilkumar Gopalakrishnapillai, PhD, Colin Correnti, PhD, Anne Kisielewski, BS, Allison Kaeding, MD, Soheil Meshinchi, MD PhD, E. Anders Kolb, MD, Sonali Barwe, PhD MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 3925.
https://doi.org/10.1182/blood-2019-130941
Published: 2019
Journal Articles

A Distinct Oncofetal B-Cell Transcriptional Program Is Activated in Infant Acute Myeloid Leukemia and Reveals Novel Therapeutic Strategies

Hamid Bolouri, PhD, Benjamin K. Johnson, PhD, Rhonda E. Ries, MA, Laura Pardo, Tiffany A. Hylkema, BS, Wanding Zhou, PhD, Jenny L. Smith, MSc, MD, Amanda R. Leonti, MS, Allison Kaeding, MD, Michael R. Loken, PhD, Jason E. Farrar, MD, Soheil Meshinchi, MD PhD, Timothy Junius Triche, Jr., PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3768.
https://doi.org/10.1182/blood-2019-123487
Published: 2019
Journal Articles

Transcriptome Profiling of Glycosylation Genes Defines Correlation with E-Selectin Ligand Expression and Clinical Outcome in AML

Amanda R. Leonti, MS, Laura Pardo, Todd A. Alonzo, PhD, Robert B. Gerbing, Lisa Eidenschink Brodersen, PhD, Rhonda E. Ries, MA, Jenny L. Smith, MSc, MD, Quy Le, PhD, Richard Aplenc, MD PhD, E. Anders Kolb, MD, John L. Magnani, PhD, William E. Fogler, PhD, Michael R. Loken, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3772.
https://doi.org/10.1182/blood-2019-124525
Published: 2019
Journal Articles

Transcriptome Analysis of Pediatric AML Reveals Non Protein-Coding RNAs Associated with Poor Survival Outcome and Treatment Resistance

Lisa Wei, BS, Rhonda E. Ries, MA, Patrick Plettner, Karen Mungall, PhD, Andrew J. Mungall, PhD, Soheil Meshinchi, MD PhD, Marco A. Marra, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2675.
https://doi.org/10.1182/blood-2019-132008
Published: 2019
Journal Articles

Demonstration of the Safety of Post Induction Infusion of Ex-Vivo Expanded Cord Blood Progenitor Cells in Pediatric Patients with Relapsed/Refractory Acute Myelogenous Leukemia

Ann Dahlberg, MD, Muna Qayed, MDMSc, Katherine Tarlock, MD, Jessica A. Pollard, MD, Filippo Milano, MD PhD, Soheil Meshinchi, MD PhD, Colleen Delaney, MD MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 2614.
https://doi.org/10.1182/blood-2019-130979
Published: 2019
Journal Articles

Long Non-Coding RNAs (lncRNAs) Are Highly Associated with Disease Characteristics and Outcome in Pediatric Acute Myeloid Leukemia - a COG and Tpaml Study

Jenny L. Smith, MSc, MD, Rhonda E. Ries, MA, Jason E. Farrar, MD, Todd A. Alonzo, PhD, Robert B. Gerbing, Amanda R. Leonti, MS, Tiffany A. Hylkema, BS, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, Edward Anders Kolb, MD, Cu Nguyen, Daoud Meerzaman, Timothy Junius Triche, Jr., PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2741.
https://doi.org/10.1182/blood-2019-127318
Published: 2019
Journal Articles

Transcriptome Profiling of Pediatric Myeloproliferative Neoplasms Demonstrates Dysregulation of Platelet-Relevant Genes and Enrichment of Inflammatory and JAK2 Mediated Complement Pathways

Nicole Kucine, MD, Amanda R. Leonti, MS, Aishwarya Krishnan, Rhonda E. Ries, MA, Ross L. Levine, MD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4203.
https://doi.org/10.1182/blood-2019-125103
Published: 2019
Journal Articles

Preliminary Lasso Regression Analysis Identifies DNA-Damage Gene Expression Signature Predictive of Clinical Outcomes in Patients Using Gemtuzumab Ozogamicin

Mohammed Gbadamosi, BS, Abdelrahman H. Elsayed, MSc, Rhonda E. Ries, MA, Soheil Meshinchi, MD PhD, Jatinder K Lamba, M.Sc., PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1401.
https://doi.org/10.1182/blood-2019-131210
Published: 2019
Journal Articles

In Vivo Evaluation of Mesothelin As a Therapeutic Target in Pediatric Acute Myeloid Leukemia

Anilkumar Gopalakrishnapillai, PhD, Allison Kaeding, MD, Christoph Schatz, PhD, Anette Sommer, PhD, Soheil Meshinchi, MD PhD, E. Anders Kolb, MD, Sonali Barwe, PhD MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 1370.
https://doi.org/10.1182/blood-2019-123794
Published: 2019
Journal Articles

CBFA2T3-GLIS2 induces Malignant Transformation of Primitive CD34+ Cord Blood Cells and Recapitulates Infant Megakaryocytic Leukemia

Tiffany A. Hylkema, BS, Laura Pardo, Keith R. Loeb, MD, Quy Le, PhD, Suzan Imren, MD, Lisa Eidenschink Brodersen, PhD, Michael R. Loken, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1444.
https://doi.org/10.1182/blood-2019-126185
Published: 2019