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Sebastien Jacquelin
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Journal Articles

Characterization of a Colony Stimulating Factor Receptor (CSF1R) Upstream Regulatory Element in Haematopoiesis

Sebastien Jacquelin, Emma Maxwell, Cameron Flegg, Yajun Liu, Isis Taylor, Ginell Ranpura, Fathima Nooru-Mohamed, Kamil A Sokolowski, Anthony Adamson, Katharine M Irvine, David A Hume
Journal: Blood
Blood (2024) 144 (Supplement 1): 4033.
https://doi.org/10.1182/blood-2024-204496
Published: 2024
Journal Articles

Genome-wide transcription factor–binding maps reveal cell-specific changes in the regulatory architecture of human HSPCs

Shruthi Subramanian, Julie A. I. Thoms, Yizhou Huang, Paola Cornejo-Páramo, Forrest C. Koch, Sebastien Jacquelin, Sylvie Shen, Emma Song, Swapna Joshi, Chris Brownlee, Petter S. Woll, Diego Chacon-Fajardo, Dominik Beck, David J. Curtis, Kenneth Yehson, Vicki Antonenas, Tracey O'Brien, Annette Trickett, Jason A. Powell, Ian D. Lewis, Stuart M. Pitson, Maher K. Gandhi, Steven W. Lane, Fatemeh Vafaee, Emily S. Wong, Berthold Göttgens, Hamid Alinejad-Rokny, Jason W. H. Wong, John E. Pimanda
Journal: Blood
Blood (2023) 142 (17): 1448–1462.
https://doi.org/10.1182/blood.2023021120
Published: 2023
Includes: Supplemental data
Journal Articles

Comparative Analysis of Genome-Scale Gene Regulatory Networks in Human Hematopoietic Stem and Myeloid Progenitor Fractions

Shruthi Subramanian, Julie A.I. Thoms, Yizhou Huang, Sebastien Jacquelin, Sylvie Shen, Emma Song, Swapna Joshi, Chris Brownlee, Petter S Woll, Diego Chacon Fajardo, Dominik Beck, David J. Curtis, Kenneth Yehson, Vicki Antonenas, Tracey O' Brien, Annette Trickett, Jason Powell, Stuart M Pitson, Maher K. Gandhi, Paola Cornejo, Emily Wong, Steven W Lane, Bertie Gottgens, Hamid Alinejad Rokny, Jason W.H Wong, John E. Pimanda
Journal: Blood
Blood (2022) 140 (Supplement 1): 2846–2848.
https://doi.org/10.1182/blood-2022-165620
Published: 2022
Journal Articles

Targeting Control of Cell Cycle Enhances the Activity of Conventional Chemotherapy in Chemotherapy-Resistant Acute Myeloid Leukemia

Victoria Y Ling, Sebastien Jacquelin, Jasmin Straube, Rohit Haldar, Yashaswini Janardhanan, Leanne T Cooper, Claudia Bruedigam, Emily Cooper, William Godfrey, Siok-Keen Tey, Lars Bullinger, Marco J Herold, Jonathan Baell, Megan Bywater, Steven W Lane
Journal: Blood
Blood (2021) 138 (Supplement 1): 2241.
https://doi.org/10.1182/blood-2021-148379
Published: 2021
Journal Articles

Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation

Sebastien Jacquelin, Jasmin Straube, Leanne Cooper, Therese Vu, Axia Song, Megan Bywater, Eva Baxter, Matthew Heidecker, Brad Wackrow, Amy Porter, Victoria Ling, Joanne Green, Rebecca Austin, Stephen Kazakoff, Nicola Waddell, Luke B. Hesson, John E. Pimanda, Frank Stegelmann, Lars Bullinger, Konstanze Döhner, Raajit K. Rampal, Dirk Heckl, Geoffrey R. Hill, Steven W. Lane
Journal: Blood
Blood (2018) 132 (26): 2707–2721.
https://doi.org/10.1182/blood-2018-04-846220
Published: 2018
Includes: Supplemental data
Journal Articles

Identification of Genetic Pathways Controlling Resistance to Standard Combination Chemotherapy in Acute Myeloid Leukemia

Victoria Y Ling, MBBS, William Godfrey, Sebastien Jacquelin, PhD, Jasmin Straube, PhD, Leanne T Cooper, Claudia Bruedigam, PhD, Siok-Keen Tey, MBBS PhDFRACP FRCPA, Lars Bullinger, MD, Marco J Herold, Megan Bywater, PhD, Steven W. Lane, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2771.
https://doi.org/10.1182/blood-2018-99-115729
Published: 2018
Journal Articles

Oncogenic-Drivers Dictate Immune Responses to Control Disease Progression in Acute Myeloid Leukaemia

Rebecca Austin, BSc, Megan Bywater, PhD, Jasmin Straube, PhD, Leanne T Cooper, Madeleine Headlam, PhD, Keyur Dave, PhD, Matthias Braun, PhD, Tobias Bald, PhD, Fernando Guimaraes, PhD, Sebastien Jacquelin, PhD, Matthew Witkowski, PhD, Iannis Aifantis, PhD, Geoffrey R Hill, MD PhD, Mark J Smyth, PhD, Steven W. Lane, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 904.
https://doi.org/10.1182/blood-2018-99-112009
Published: 2018
Journal Articles

Crispr-Cas9 Mediated Disruption of Dnmt3a in JakV617F Hematopoietic Stem Cells Accelerates Disease Phenotype and Induces Lethal Myelofibrosis

Sebastien Jacquelin, PhD, Emma Dishington, Therese Vu, Axia Song, Matthew Heidecker, Solene Guignes, Claudia Bruedigam, PhD, Joanne Sutton, Geoffrey R Hill, MD PhD, Nicole Cloonan, PhD, Dirk Heckl, PhD, Steven W Lane, PhD
Journal: Blood
Blood (2016) 128 (22): 794.
https://doi.org/10.1182/blood.V128.22.794.794
Published: 2016
Journal Articles

Cdx2 Cooperates with Flt3-ITD to Induce Acute Myeloid Leukaemia in Mice

Therese Vu, BSc, Claudia Bruedigam, Axia Song, Solene Guignes, Rebecca Austin, Sebastien Jacquelin, Alistair Chalk, Carl Walkley, PhD BPharm, Claudia Scholl, Stefan Fröhling, MD, Steven W. Lane, MD
Journal: Blood
Blood (2015) 126 (23): 557.
https://doi.org/10.1182/blood.V126.23.557.557
Published: 2015
Journal Articles

CX3CR1 reduces Ly6C high -monocyte motility within and release from the bone marrow after chemotherapy in mice

Sébastien Jacquelin, Fabrice Licata, Karim Dorgham, Patricia Hermand, Lucie Poupel, Elodie Guyon, Philippe Deterre, David A. Hume, Christophe Combadière, Alexandre Boissonnas
Journal: Blood
Blood (2013) 122 (5): 674–683.
https://doi.org/10.1182/blood-2013-01-480749
Published: 2013
Includes: Multimedia, Supplemental data
Journal Articles

Prognostic Significance of Complement System Activation After Allogeneic Hematopoietic Stem Cell Transplantation.

Marie T Rubio, Marie A Durey-Dragon, Yi Wang, Jacques Blouin, Sebastien Jacquelin, Pierre Milpied, Felipe Suarez, Richard Delarue, Agnès Buzyn, Bruno Varet, Wolf H Fridman, Véronique Fremeaux-Bacchi, Olivier Hermine
Journal: Blood
Blood (2009) 114 (22): 1166.
https://doi.org/10.1182/blood.V114.22.1166.1166
Published: 2009