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Journal Articles

Proteolytic Control and Therapeutic Targeting of Oncogenic Gene Expression in Acute Myeloid Leukemia

Masahiro Uni, Asher Preska Steinberg, Alicia Slavit, Sophia Rha, Shuyuan Cheng, Laura K. Schmalbrock, Jiayu Su, Jing Ma, Andrew McPherson, Charles G. Mullighan, Torsten Haferlach, Ilaria Iacobucci, Jeffery M Klco, Raul Rabadan, Alex Kentsis

Blood (2024) 144 (Supplement 1): 4149.

https://doi.org/10.1182/blood-2024-200137

Published: 2024

Journal Articles

A Niche Driven Mechanism Determines Response to ATRA and a Mutation-Independent Therapeutic Approach for MDS and AML

Ioanna Mosialou, Abdullah Mahmood Ali, Alvaro Cuesta-Dominguez, Rossella Labella, Voula Vgenopoulou, Brygida Bisikirska, Marta Galan-Diez, Anqi Wang, Jan Philipp Bewersdorf, Cui Liang, Mael Heiblig, Joseph G Jurcic, Ellin Berman, Raul Rabadan, Steven M. Kornblau, Guillermo Garcia-Manero, Azra Raza, Stavroula Kousteni

Blood (2024) 144 (Supplement 1): 5788.

https://doi.org/10.1182/blood-2024-212307

Published: 2024

Journal Articles

Integrated Omics to Dissect the Landscape in Chemosensitive and Refractory Extranodal Natural-Killer T-Cell Lymphoma (ENKTCL): A Global Study of the PETAL (PEripheral T-Cell Lymphoma) Consortium

Blood (2024) 144 (Supplement 1): 6207.

https://doi.org/10.1182/blood-2024-208838

Published: 2024

Journal Articles

Role of the S1P Signaling Pathway in the Pathogenesis of Angioimmunoblastic T-Cell Lymphoma

Wen-Hsuan Wendy Lin, Jose Rodriguez Cortes, Mick Aitken, Clara Reglero, Anouchka Laurent, Anisha Cooke, Laura Belver, Govind Bhagat, Raul Rabadan, Adolfo A. Ferrando, Teresa Palomero

Blood (2023) 142 (Supplement 1): 526.

https://doi.org/10.1182/blood-2023-174090

Published: 2023

Journal Articles

A Targetable Bone Marrow-Niche Axis for the Treatment of Acute Myeloid Leukemia

Marta Galan-Diez, Florence Borot, Abdullah M. Ali, Junfei Zhao, Eva Gil-Iturbe, Xiaochuan Shan, Xi-Ping Huang, Irwin Kurland, Bryan L. Roth, Matthias Quick, Siddhartha Mukherjee, Raul Rabadan, Martin P. Carroll, Azra Raza, Stavroula Kousteni

Blood (2021) 138 (Supplement 1): 4456.

https://doi.org/10.1182/blood-2021-147741

Published: 2021

Journal Articles

HHV-6 in the Lymphoma Microenvironment: Both Chicken and Egg?

Genevieve M Crane, Dmitry Tychinin, Anton Karelin, Aleksandr Cherdintsev, Olga Kudryashova, Evgeniy Egorov, Sandrine Degryse, Nikita Kotlov, Alexander Bagaev, Joseph Casano, Jonathan Reichel, Lisa Giulino Roth, Mikhail Roshal, Sakellarios Zairis, Raul Rabadan, Olivier Elemento, Giorgio Inghirami, Ethel Cesarman

Blood (2021) 138 (Supplement 1): 1377.

https://doi.org/10.1182/blood-2021-146336

Published: 2021

Journal Articles

Expression of Vav1-Myo1F Fusion Affects T-Cell Differentiation and Induces T-Cell Lymphoma

Jose Rodriguez Cortes, PhD, Robert Albero Gallego, PhD, Ioan Filip, PhD, Juan Angel Patino, PhD, Anisha Cooke, Wen-Hsuan Lin, Anouchka P Laurent, Bobby B Shih, Aidan Quinn, Raul Rabadan, PhD, Adolfo A. Ferrando, MD PhD, Teresa Palomero, PhD

Blood (2020) 136 (Supplement 1): 4.

https://doi.org/10.1182/blood-2020-136081

Published: 2020

Journal Articles

Transcriptional Control of HP1a By the RNA Binding Proteins Rbmx/L1 Maintain Chromatin State in Myeloid Leukemia

Diu T.T. Nguyen, DPhil, Camila Prieto, PhD, Zhaoqi Liu, PhD, Justin Wheat, Alexendar Perez, Saroj Gourkanti, BA, Timothy Chou, BS, Ersilia Barin, Arthur Chow, BS, James Taggart, BA, Katerina Hoskova, Meera Dhodapkar, Alexandra Schurer, BS, Trevor Stephen Barlowe, BA, Ly Vu, PhD, Christina Leslie, PhD, Ulrich G. Steidl, MDPhD, Raul Rabadan, PhD, Michael G. Kharas, PhD

Blood (2020) 136 (Supplement 1): 15.

https://doi.org/10.1182/blood-2020-142229

Published: 2020

Journal Articles

Mechanisms of Therapeutic Response to Tipifarnib in a Mouse Model of Angioimmunoblastic T-Cell Lymphoma

Jose Rodriguez Cortes, Anisha Cooke, Aidan Quinn, Bobby B Shih, Ioan Filip, PhD, Juan Angel Patino, PhD, Raul Rabadan, PhD, Adolfo Ferrando, MD, PhD, Teresa Palomero, PhD

Blood (2020) 136 (Supplement 1): 9.

https://doi.org/10.1182/blood-2020-135838

Published: 2020

Journal Articles

RNA Sequencing of Hodgkin Lymphoma Reed-Sternberg Cells Uncovers a Plasma Cell Signature and Escape from NK Cell Recognition

Ethel Cesarman, MD PhD, Mikhail Roshal, MD PhD, Jonathan Reichel, PhD, Wagner Florian, PhD, Bhavneet Binder, Sakellarios Zairis, Jouliana Sadek, PhD, Joshua Brody, MD, Raul Rabadan, PhD, Sandeep Dave, MD

Blood (2019) 134 (Supplement_1): 549.

https://doi.org/10.1182/blood-2019-131163

Published: 2019

Journal Articles

Role of Vav1 Genomic Alterations in T-Cell Differentiation and Transformation in Peripheral T-Cell Lymphoma

Jose Rodriguez Cortes, PhD, Anisha R. Cooke, Aidan Quinn, Ioan Filip, PhD, Juan Angel Patino, PhD, Raul Rabadan, PhD, Adolfo A. Ferrando, MD PhD, Teresa Palomero, PhD

Blood (2019) 134 (Supplement_1): 1482.

https://doi.org/10.1182/blood-2019-129438

Published: 2019

Journal Articles

Mutations in the RNA Splicing Factor SF3B1 Promote Transformation through MYC Stabilization

Akihide Yoshimi, MD, Zhaoqi Liu, PhD, Wang Jiguang, Hana Cho, MSc, Stanley C Lee, PhD, Michelle Ki, BSc, Lillian E Bitner, BSc, Timothy Chu, Anthony R Mato, MD, Peter P. Ruvolo, PhD, Giulia Fabbri, Laura Pasqualucci, MD, Raul Rabadan, PhD, Omar I Abdel-Wahab, MD

Blood (2018) 132 (Supplement 1): 882.

https://doi.org/10.1182/blood-2018-99-110328

Published: 2018

Journal Articles

Suppression of GATA3 Binding Drives Selective Abrogation of NOTCH1-MYC Enhancer Activity By Nucleosome Invasion in Thymocyte Development and Leukemia

Laura Belver, PhD, Alexander Y Yang, Daniel Herranz, PharmD, Aidan Quinn, Francesco G Brundu, PhD, Pablo Perez-Duran, PhD, Silvia Alvarez, PhD, Devya Gurung, Pedro P Rocha, PhD, Ramya Raviram, PhD, Marissa Rashkovan, PhD, Raul Rabadan, PhD, Adolfo A. Ferrando, MD PhD

Blood (2018) 132 (Supplement 1): 545.

https://doi.org/10.1182/blood-2018-99-119423

Published: 2018

Journal Articles

High Throughput Droplet Single-Cell Genotyping of Transcriptomes (GoT) Reveals the Cell Identity Dependency of the Transcriptional Output of Somatic Mutations

Anna S Nam, MD, Kyu-Tae Kim, PhD, Ronan Chaligne, PhD, Franco Izzo, PhD, Chelston Ang, MS, Nathaniel Omans, MS, Alessandro Pastore, Justin Taylor, MD, Alicia Alonso, Wayne Tam, MD PhD, Ronald Hoffman, MD, Joseph Scandura, MDPhD, Raul Rabadan, PhD, Omar I Abdel-Wahab, MD, Peter Smibert, PhD, Dan A. Landau, MD PhD

Blood (2018) 132 (Supplement 1): 541.

https://doi.org/10.1182/blood-2018-99-119236

Published: 2018

Journal Articles

Pervasive mutations of JAK-STAT pathway genes in classical Hodgkin lymphoma

Blood (2018) 131 (22): 2454–2465.

https://doi.org/10.1182/blood-2017-11-814913

Published: 2018

Includes: Supplemental data

Journal Articles

Clonal Evolution Mechanisms and Collateral Sensitivity to Impdh Inhibitor Therapy in Relapsed Lymphoblastic Leukemia

Chelsea Dieck, Gannie Tzoneva, PhD, Koichi Oshima, MD PhD, Alberto Ambesi-Impiombato, Marta Sanchez-Martin, PhD, Maria Luisa Sulis, MD, Motohiro Kato, MD PhD, Katsuyoshi Koh, MD, Maddalena Paganin, PhD, Giuseppe Basso, MD, Julie M. Gastier-Foster, PhD, Mignon L. Loh, MD, Renate Kirschner-Schwabe, PhD, Chioma Madubata, Raul Rabadan, Adolfo A. Ferrando, MD PhD

Blood (2017) 130 (Supplement 1): 2602.

https://doi.org/10.1182/blood.V130.Suppl_1.2602.2602

Published: 2017

Journal Articles

Repurposing Dasatinib for Ibrutinib-Resistant Diffuse Large B-Cell Lymphoma

Claudio Scuoppo, PhD, Wang Jiguang, Mirjana Persaud, Sandeep Mittan, Laura Pasqualucci, MD, Raul Rabadan, Carla Grandori, Riccardo Dalla-Favera, MD

Blood (2017) 130 (Supplement 1): 3843.

https://doi.org/10.1182/blood.V130.Suppl_1.3843.3843

Published: 2017

Journal Articles

New Recurrently Mutated Genes in Classical Hodgkin Lymphoma Revealed By Whole-Exome Sequencing of Microdissected Tumor Cells

Enrico Tiacci#, Alexander Penson#, Gianluca Schiavoni#, Erik Ladewig#, Elisabetta Fortini#, Yuchun Wang, Ariele Spanhol-Rosseto, Alessandra Venanzi, Alessandro M. Gianni, Simonetta Viviani, MD, Antonello Cabras, Barbara Crescenzi, Cristina Mecucci, MD PhD, Laura Pasqualucci°, Raul Rabadan°, Brunangelo Falini°

Blood (2016) 128 (22): 1088.

https://doi.org/10.1182/blood.V128.22.1088.1088

Published: 2016

Journal Articles

Mutational Landscape, Clonal Evolution Patterns and Role of RAS Mutations in Relapsed Acute Lymphoblastic Leukemia

Blood (2016) 128 (22): 4068.

https://doi.org/10.1182/blood.V128.22.4068.4068

Published: 2016

Journal Articles

VAV1 Activating Mutations and Translocations in Peripheral T-Cell Lymphomas

Blood (2016) 128 (22): 2741.

https://doi.org/10.1182/blood.V128.22.2741.2741

Published: 2016

NARROW

Proteolytic Control and Therapeutic Targeting of Oncogenic Gene Expression in Acute Myeloid Leukemia

A Niche Driven Mechanism Determines Response to ATRA and a Mutation-Independent Therapeutic Approach for MDS and AML

Integrated Omics to Dissect the Landscape in Chemosensitive and Refractory Extranodal Natural-Killer T-Cell Lymphoma (ENKTCL): A Global Study of the PETAL (PEripheral T-Cell Lymphoma) Consortium

Role of the S1P Signaling Pathway in the Pathogenesis of Angioimmunoblastic T-Cell Lymphoma

A Targetable Bone Marrow-Niche Axis for the Treatment of Acute Myeloid Leukemia

HHV-6 in the Lymphoma Microenvironment: Both Chicken and Egg?

Expression of Vav1-Myo1F Fusion Affects T-Cell Differentiation and Induces T-Cell Lymphoma

Transcriptional Control of HP1a By the RNA Binding Proteins Rbmx/L1 Maintain Chromatin State in Myeloid Leukemia

Mechanisms of Therapeutic Response to Tipifarnib in a Mouse Model of Angioimmunoblastic T-Cell Lymphoma

RNA Sequencing of Hodgkin Lymphoma Reed-Sternberg Cells Uncovers a Plasma Cell Signature and Escape from NK Cell Recognition

Role of Vav1 Genomic Alterations in T-Cell Differentiation and Transformation in Peripheral T-Cell Lymphoma

Mutations in the RNA Splicing Factor SF3B1 Promote Transformation through MYC Stabilization

Suppression of GATA3 Binding Drives Selective Abrogation of NOTCH1-MYC Enhancer Activity By Nucleosome Invasion in Thymocyte Development and Leukemia

High Throughput Droplet Single-Cell Genotyping of Transcriptomes (GoT) Reveals the Cell Identity Dependency of the Transcriptional Output of Somatic Mutations

Pervasive mutations of JAK-STAT pathway genes in classical Hodgkin lymphoma

Clonal Evolution Mechanisms and Collateral Sensitivity to Impdh Inhibitor Therapy in Relapsed Lymphoblastic Leukemia

Repurposing Dasatinib for Ibrutinib-Resistant Diffuse Large B-Cell Lymphoma

New Recurrently Mutated Genes in Classical Hodgkin Lymphoma Revealed By Whole-Exome Sequencing of Microdissected Tumor Cells

Mutational Landscape, Clonal Evolution Patterns and Role of RAS Mutations in Relapsed Acute Lymphoblastic Leukemia

VAV1 Activating Mutations and Translocations in Peripheral T-Cell Lymphomas

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American Society of Hematology

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ASH Publications

American Society of Hematology

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