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Journal Articles

ETS1 Recruits the Canonical Baf Complex to Reactivate the Hematopoietic Stem Cell MYB Enhancer in the T-Cell Leukemia Context

Carea Mullin, Karena Hsijan Lin, Anna McCarter, Elizabeth Choe, Shannon Liang, Qing Wang, Ashley Melnick, Zeel Shukla, Cher Sha, Ashwin Iyer, Rohan Kodgule, Yamei Deng, Felipe Leprevost, Kelly R. Barnett, Daniel Savic, Alexey Nesvizhskii, Russell J. H. Ryan, Mark Chiang
Journal: Blood
Blood (2024) 144 (Supplement 1): 203.
https://doi.org/10.1182/blood-2024-207624
Published: 2024
Journal Articles

Heterozygous ddx41 Mutation Drive Age-Dependent Hematopoietic Stem and Progenitor Cell Dysfunction

Maria Feliz Norberto, Yanhua Wang, Qing Wang, Anastasia Nizhnik, Bianca A Ulloa, Sofia De Oliveira, Teresa V. Bowman
Journal: Blood
Blood (2024) 144 (Supplement 1): 4576.
https://doi.org/10.1182/blood-2024-210172
Published: 2024
Journal Articles

Cdc73 protects Notch-induced T-cell leukemia cells from DNA damage and mitochondrial stress

Ashley F. Melnick, Carea Mullin, Karena Lin, Anna C. McCarter, Shannon Liang, Yiran E. Liu, Qing Wang, Nicole A. Jerome, Elizabeth Choe, Nicholas Kunnath, Geethika Bodanapu, Fatema Akter, Brian Magnuson, Surinder Kumar, David B. Lombard, Andrew G. Muntean, Mats Ljungman, JoAnn Sekiguchi, Russell J. H. Ryan, Mark Y. Chiang
Journal: Blood
Blood (2023) 142 (25): 2159–2174.
https://doi.org/10.1182/blood.2023020144
Published: 2023
Includes: Supplemental data
Journal Articles

Morphologic and Genetic Features of Unclassifiable Chronic Myeloid Neoplasms: Five-Year Experience of a Canadian Provincial Referral Center

Xiu Qing Wang, Monika Hudoba, Robert Guo, Eric McGinnis
Journal: Blood
Blood (2023) 142 (Supplement 1): 6432.
https://doi.org/10.1182/blood-2023-187775
Published: 2023
Journal Articles

Oncogenic JAK2/STAT Signaling Molecules Activation Is Associated with PD-L1 Upregulation in Acute Myeloid Leukemia

Jiani Chai, Jui Choudhuri, Qing Wang, Yanan Fang, Yang Shi, Wa Shen, Swati Goel, Ioannis Mantzaris, Aditi Shastri, R. Alejandro Sica, Nishi Shah, Kira Gritsman, Marina Konopleva, Noah Kornblum, Amit Verma, Mendel Goldfinger, Yanhua Wang, Xuejun Tian
Journal: Blood
Blood (2022) 140 (Supplement 1): 6256–6257.
https://doi.org/10.1182/blood-2022-162857
Published: 2022
Journal Articles

Resistance to the Non-Covalent BTK Inhibitor Pirtobrutinib

Aishath S Naeem, Filippo Utro, Qing Wang, Justin Cha, Mauno Vihinen, Stephen P. Martindale, Yinglu Zhou, Svitlana Tyekucheva, Annette S. Kim, Stacey M. Fernandes, Rayan Fardoun, Gordon Saksena, Kahn Rhrissorrakrai, Chaya Levovitz, Brian P Danysh, Kara Slowik, Raquel Jacobs, Matthew S. Davids, Rula Zain, Edvard CI Smith, Ignaty Leshchiner, Laxmi Parida, Gad Getz, Jennifer R. Brown
Journal: Blood
Blood (2022) 140 (Supplement 1): 6981–6982.
https://doi.org/10.1182/blood-2022-160279
Published: 2022
Journal Articles

Polymerase-Associated Factor Complex (PAFc) Protects Notch-Induced Leukemia Cells from DNA Damage and Mitochondrial Stress

Ashley Melnick, Anna McCarter, Shannon Liang, Nicole Dean, Elizabeth Choe, Nicholas Kunnath, Brian Magnuson, Karena Lin, Qing Wang, Surinder Kumar, David Lombard, Russell J.H. Ryan, Mats Ljungman, Mark Y Chiang
Journal: Blood
Blood (2022) 140 (Supplement 1): 1005–1006.
https://doi.org/10.1182/blood-2022-157573
Published: 2022
Journal Articles

Native Stem Cell Transcriptional Circuits in Normal and Malignant Early-Stage T Cells

Mark Y Chiang, Qing Wang, Carea Mullin, Elizabeth Choe, Nicole Dean, Fatema Akter, Siyi Chen, Ashley Melnick, Anna McCarter, Rohan Kodgule, Raghu Vannam, Christopher J. Ott, Russell J.H. Ryan
Journal: Blood
Blood (2022) 140 (Supplement 1): 1003–1004.
https://doi.org/10.1182/blood-2022-156266
Published: 2022
Journal Articles

Megakaryocytic emperipolesis as a dyshematopoietic feature in acute myeloid leukemia with inv(16)

Xiu Qing Wang, Eric McGinnis
Journal: Blood
Blood (2022) 139 (5): 798.
https://doi.org/10.1182/blood.2021014251
Published: 2022
Journal Articles

A Novel Risk Scoring System to Predict Survival in Soft Tissue-Related Extramedullary Multiple Myeloma

Beihui Huang, Qing Wang, Wuping Li, Ying Zhao, Juan Li
Journal: Blood
Blood (2021) 138 (Supplement 1): 4749.
https://doi.org/10.1182/blood-2021-144837
Published: 2021
Journal Articles

Examination of Clinically-Derived p210 BCR/ABL Rhogef Mutations in a Murine Bone Marrow Transplantation Model of CML

Bryan T. Ciccarelli, MD PhD, Tinghui Hu, PhD, Qing Wang, MD PhD, Julia J. Kim, MD, Ian P. Whitehead, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 24.
https://doi.org/10.1182/blood-2020-141685
Published: 2020
Journal Articles

Updated Results from the Phase II Study of Orelabrutinib Monotherapy in Chinese Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Cell Leukemia

Wei Xu, MD PhD, Yongping Song, MD, Tingyu Wang, Shenmiao Yang, Lihong Liu, MD, Yu Hu, MD, Wei Zhang, Jianfeng Zhou, MD PhD, Sujun Gao, Kaiyang Ding, Huilai Zhang, MD PhD, Zunmin Zhu, MD, Shun-Qing Wang, Bing Xu, MD PhD, Jianda Hu, Ting Liu, MD PhD, Chunyan Ji, MD, Zhongjun Xia, MDPhD, Yan Li, PhDMD, Xin Wang, MDPhD, Huaqiang Zhu, MD, Renbin Zhao, PhD, Bin Zhang, PhD, Zhixin Xu, MD PhD, Jianyong Li, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 26–27.
https://doi.org/10.1182/blood-2020-134531
Published: 2020
Journal Articles

Combination of Gatekeeper Mutations and Cysteine 481 Replacement Causes Super Resistance to the Irreversible BTK Inhibitors Ibrutinib, Acalabrutinib and Zanubrutinib

Hernando Yesid Estupiñan Velasquez, Yuye Shi, MD PhD, Dara K. Mohammad, PhD, Qing Wang, Mauno Vihinen, PhD, Rula Zain, PhD, Anna Berglöf, PhD VMD, Edvard CI Smith, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5759.
https://doi.org/10.1182/blood-2019-123398
Published: 2019
Journal Articles

Ets1 Enhances Context-Dependent Notch1 Activity in T-Cell Leukemia

Anna McCarter, BS, Ran Yan, Amparo Serna Alarcon, Catherine Chang, Erin Kim, Cher Sha, Yiran Liu, Qing Wang, PhD, Luke F. Peterson, PhD, Rork Kuick, Russell Ryan, MD, Moshe Talpaz, MD, Linda Samuelson, PhD, Michael Ostrowski, PhD, Mark Y Chiang, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2595.
https://doi.org/10.1182/blood-2018-99-111376
Published: 2018
Journal Articles

Donor NKG2C Copy Number: An Independent Predictor for CMV Reactivation after Double Cord Blood Transplantation

May Daher, Kai Cao, MS, MD, Rafet Basar, MD, David Marin, MD, Takuye Sekine, PhD, Gabriela Rondon, MD, Weicheng Zhao, MS, Nathaniel T Smith, MS, Qing Wang, BS, Li Li, MD, Rima M. Saliba, PhD, Sai Ravi Kiran Pingali, MD, Uday Popat, MD, Chitra Hosing, MD, Amanda L. Olson, MD, Betul Oran, MD MS, Rohtesh S. Mehta, MD MPH, MS, Richard E Champlin, MD, Elizabeth J. Shpall, MD, Katayoun Rezvani, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2077.
https://doi.org/10.1182/blood-2018-99-114407
Published: 2018
Journal Articles

Stage-specific roles for Zmiz1 in Notch-dependent steps of early T-cell development

Qing Wang, Ran Yan, Nancy Pinnell, Anna C. McCarter, Yeonjoo Oh, Yiran Liu, Cher Sha, Noah F. Garber, Yitong Chen, Qingqing Wu, Chia-Jui Ku, Ivy Tran, Amparo Serna Alarcon, Rork Kuick, James Douglas Engel, Ivan Maillard, Tomasz Cierpicki, Mark Y. Chiang
Journal: Blood
Blood (2018) 132 (12): 1279–1292.
https://doi.org/10.1182/blood-2018-02-835850
Published: 2018
Includes: Supplemental data
Journal Articles

Very Early Effects of Ibrutinib on Tumor and Immune Cells in Blood and Lymph Nodes in Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) Patients

Marzia Palma, MD PhD, Aleksandra Krstic, PhD, Anna Berglöf, PhD, Qing Wang, PhD, Emelie Blomberg, PhD, Stephan Meinke, PhD, Masood Kamali-Moghaddam, PhD, Qiujin Shen, PhD, Georg Jaremko, MD PhD, Jeanette Lundin, MD PhD, Eva Kimby, MD professor, Petter Höglund, MD PhD, Robert Månsson, PhD, Anders Österborg, MD PhD, Edvard Smith, PhD
Journal: Blood
Blood (2016) 128 (22): 3235.
https://doi.org/10.1182/blood.V128.22.3235.3235
Published: 2016
Journal Articles

The Direct Notch1 Cofactor Zmiz1 Differentially Regulates Notch1 Signals in a Stage-Specific Manner to Preserve Early T-Cell Precursors and Expand Committed T Cells

Qing Wang, Ran Yan, Nancy Pinnell, Yiran Liu, Amparo Serna Alarcon, Jason Qin, Yitong Chen, Erin Kim, Noah Garber, Ivan Maillard, MD PhD, Tomasz Cierpicki, PhD, Mark Chiang, MD PhD
Journal: Blood
Blood (2016) 128 (22): 426.
https://doi.org/10.1182/blood.V128.22.426.426
Published: 2016
Journal Articles

High selective pressure for Notch1 mutations that induce Myc in T-cell acute lymphoblastic leukemia

Mark Y. Chiang, Qing Wang, Anna C. Gormley, Sarah J. Stein, Lanwei Xu, Olga Shestova, Jon C. Aster, Warren S. Pear
Journal: Blood
Blood (2016) 128 (18): 2229–2240.
https://doi.org/10.1182/blood-2016-01-692855
Published: 2016
Includes: Supplemental data
Journal Articles

Interim Results of a Multi-Center Observational Study of Current Treatment Patterns for Patients with Severe Aplastic Anemia (SAA), Very Severe Aplastic Anemia (VSAA) and Transfusion-Dependent Non-Severe Aplastic Anemia (TD-NSAA) in China

Feng-Kui Zhang, Xiao-Fan Zhu, Hai-Long He, Shun-Qing Wang, Jing-Yan Tang, Dao-Bin Zhou, Dong-Hua Zhang, Yu-Hong Zhou, De-pei Wu, Wei Li, Ling-Hui Xia, Huan-Ling Zhu, Feng Liu, Hong-Xia Shi, Xi Zhang, Fang Zhou, Jian-Da Hu, Jian-Pei Fang, Xie-Qun Chen, Tie-Zhen Ye, Ying-Min Liang, Jie Jin
Journal: Blood
Blood (2015) 126 (23): 4505.
https://doi.org/10.1182/blood.V126.23.4505.4505
Published: 2015