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Journal Articles

HDAC8 regulates long-term hematopoietic stem-cell maintenance under stress by modulating p53 activity

Wei-Kai Hua, Jing Qi, Qi Cai, Emily Carnahan, Maria Ayala Ramirez, Ling Li, Guido Marcucci, Ya-Huei Kuo
Journal: Blood
Blood (2017) 130 (24): 2619–2630.
https://doi.org/10.1182/blood-2017-03-771386
Published: 2017
Includes: Supplemental data
Journal Articles

HDAC8 Regulates Long-Term Hematopoietic Stem Cell Maintenance Under Stress By Modulating p53 Activity

Wei-Kai Hua, PhD, Jing Qi, PhD, Qi Cai, PhD, Emily Carnahan, MS, Maria Ayala Ramirez, Ling Li, PhD, Guido Marcucci, MD, Ya-Huei Kuo, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1146.
https://doi.org/10.1182/blood.V130.Suppl_1.1146.1146
Published: 2017
Journal Articles

MiR-126 Promotes Leukemogenesis in Inv(16) Acute Myeloid Leukemia

Casey J Brewer, PhD, Guerry Jeanne Cook, PhD, Bin Zhang, PhD, Le Xuan Truong Nguyen, PhD, Jing Qi, PhD, Wei-Kai Hua, PhD, Qi Cai, PhD, Emily Carnahan, MS, Ayelet Marom, PhD, Ling Li, PhD, Marcin Kortylewski, PhD, Guido Marcucci, MD, Ya-Huei Kuo, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 301.
https://doi.org/10.1182/blood.V130.Suppl_1.301.301
Published: 2017
Journal Articles

HDAC8 Regulates Long-Term Hematopoietic Stem Cell Quiescence and Maintenance

Wei-Kai Hua, PhD, Jing Qi, PhD, Qi Cai, PhD, Emily Carnahan, Ling Li, PhD, Vu N. Ngo, PhD, Guido Marcucci, MD, Ya-Huei Kuo, PhD
Journal: Blood
Blood (2016) 128 (22): 1468.
https://doi.org/10.1182/blood.V128.22.1468.1468
Published: 2016
Journal Articles

CBFβ-SMMHC creates aberrant megakaryocyte-erythroid progenitors prone to leukemia initiation in mice

Qi Cai, Robin Jeannet, Wei-Kai Hua, Guerry J. Cook, Bin Zhang, Jing Qi, Hongjun Liu, Ling Li, Ching-Cheng Chen, Guido Marcucci, Ya-Huei Kuo
Journal: Blood
Blood (2016) 128 (11): 1503–1515.
https://doi.org/10.1182/blood-2016-01-693119
Published: 2016
Includes: Supplemental data
Journal Articles

Serum-resistant CpG-STAT3 decoy for targeting survival and immune checkpoint signaling in acute myeloid leukemia

Qifang Zhang, Dewan Md Sakib Hossain, Priyanka Duttagupta, Dayson Moreira, Xingli Zhao, Haejung Won, Ralf Buettner, Sergey Nechaev, Marcin Majka, Bin Zhang, Qi Cai, Piotr Swiderski, Ya-Huei Kuo, Stephen Forman, Guido Marcucci, Marcin Kortylewski
Journal: Blood
Blood (2016) 127 (13): 1687–1700.
https://doi.org/10.1182/blood-2015-08-665604
Published: 2016
Includes: Supplemental data
Journal Articles

Inhibition of HDAC8 Reactivates p53 and Abrogates Leukemia Stem Cell Activity in CBFβ-SMMHC Associated Acute Myeloid Leukemia

Jing Qi, PhD, Qi Cai, PhD, Sandeep Singh, Ling Li, PhD, Hongjun Liu, Tinisha McDonald, B.S., Allen Lin, Ravi Bhatia, MD, wei-Jan Huang, PhD, chung-I Chang, ya-Huei Kuo, PhD
Journal: Blood
Blood (2014) 124 (21): 363.
https://doi.org/10.1182/blood.V124.21.363.363
Published: 2014
Journal Articles

CBFβ-SMMHC Impairs Erythroid Differentiation and Induces Expansion of Aberrant Megakaryocytic/Erythroid Progenitors Capable of Leukemia Initiation

Qi Cai, PhD, Robin Jeannet, PhD, Hongjun Liu, ya-Huei Kuo, PhD
Journal: Blood
Blood (2014) 124 (21): 2149.
https://doi.org/10.1182/blood.V124.21.2149.2149
Published: 2014
Journal Articles

Aberrant Megakaryocytic/Erythroid Progenitors Contributes To Transformation Of Cbfb-SMMHC Induced Acute Myeloid Leukemia

Qi Cai, PhD, Robin Jeannet, PhD, Hongjun Liu, Ya-Huei Kuo, PhD
Journal: Blood
Blood (2013) 122 (21): 1652.
https://doi.org/10.1182/blood.V122.21.1652.1652
Published: 2013
Journal Articles

Selective Targeting Of Inv(16)+ AML Stem Progenitor Cells By Inhibiting HDAC8

Jing Qi, PhD, Sandeep Singh, Qi Cai, PhD, Ling Li, PhD, Hongjun Liu, Hieu Vu, wei-Jan Huang, PhD, Tinisha McDonald, Allen Lin, chung-I Chang, Ravi Bhatia, MD, Ya-Huei Kuo, PhD
Journal: Blood
Blood (2013) 122 (21): 224.
https://doi.org/10.1182/blood.V122.21.224.224
Published: 2013
Journal Articles

CBFβ-SMMHC Inactivates p53 Tumor Suppressor Through Aberrant Protein Interaction and Recruitment of HDAC8

Jing Qi, Sandeep Singh, Qi Cai, PhD, Hongjun Liu, Hieu Vu, Sriram Balasubramanian, Ya-Huei Kuo, PhD
Journal: Blood
Blood (2012) 120 (21): 772.
https://doi.org/10.1182/blood.V120.21.772.772
Published: 2012
Journal Articles

Alcam Mediated Interaction Regulates Normal Hematopoietic Stem Cell Function and Cbfβ-SMMHC Induced Leukemogenesis

Robin Jeannet, PhD, Qi Cai, PhD, Hongjun Liu, Hieu Vu, Ya-Huei Kuo, PhD
Journal: Blood
Blood (2012) 120 (21): 4091.
https://doi.org/10.1182/blood.V120.21.4091.4091
Published: 2012
Journal Articles

Alcam Mediated Cellular Interaction Regulates Hematopoietic Stem Cell Repopulation and Self-Renewal

Robin Jeannet, PhD, Qi Cai, PhD, Hongjun Liu, Hieu Vu, Ya-Huei Kuo, PhD
Journal: Blood
Blood (2011) 118 (21): 1291.
https://doi.org/10.1182/blood.V118.21.1291.1291
Published: 2011
Journal Articles

Treatment of Hematological Malignancies in Central Nervous System with Idarubicin and Teniposide Containing Regimens.

Chun Wang, MD, PhD, Xiaojun He, MD, Qi Cai, MD, Jun Zhu, MD, Haitao Bai, MD
Journal: Blood
Blood (2005) 106 (11): 4731.
https://doi.org/10.1182/blood.V106.11.4731.4731
Published: 2005