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Journal Articles

The Aryl Hydrocarbon Receptor Defines a Unique Genomic and Immune Signature in AML Characterized By Monocytic Differentiation, Venetoclax Resistance and Is Targetable By Ahr Antagonist

Jennifer N. Saultz, Daniel Bottomly, Faith Burns, Kaelan Byrd, Yoko Kosaka, Shannon K. McWeeney, Stephen E. Kurtz, Guang Fan, Andy Kaempf, Karen McGovern, Lei Wang, Marta Sanchez-Martin, Dan S Kaufman, Evan F. Lind, Jeffrey W. Tyner
Journal: Blood
Blood (2022) 140 (Supplement 1): 3071–3072.
https://doi.org/10.1182/blood-2022-163166
Published: 2022
Journal Articles

Aryl Hydrocarbon Receptor (AHR) Gene Expression in AML Is Associated with FLT3-ITD+ AML and HLA-E Induced Immune Resistance Reversed By Ik-364

Jennifer N. Saultz, Evan F. Lind, Jeffrey W. Tyner, Kaelan Byrd, Shannon K. McWeeney, Yoko Kosaka, Karen McGovern, Lei Wang, Marta Sanchez-Martin
Journal: Blood
Blood (2021) 138 (Supplement 1): 1161.
https://doi.org/10.1182/blood-2021-147589
Published: 2021
Journal Articles

Clonal Evolution Mechanisms and Collateral Sensitivity to Impdh Inhibitor Therapy in Relapsed Lymphoblastic Leukemia

Chelsea Dieck, Gannie Tzoneva, PhD, Koichi Oshima, MD PhD, Alberto Ambesi-Impiombato, Marta Sanchez-Martin, PhD, Maria Luisa Sulis, MD, Motohiro Kato, MD PhD, Katsuyoshi Koh, MD, Maddalena Paganin, PhD, Giuseppe Basso, MD, Julie M. Gastier-Foster, PhD, Mignon L. Loh, MD, Renate Kirschner-Schwabe, PhD, Chioma Madubata, Raul Rabadan, Adolfo A. Ferrando, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2602.
https://doi.org/10.1182/blood.V130.Suppl_1.2602.2602
Published: 2017
Journal Articles

Mechanisms of NT5C2 mutations Driving Thiopurine Resistance in Acute Lymphoblastic Leukemia

Chelsea Dieck, Gannie Tzoneva, PhD, Farhad Forouhar, Zachary Carpenter, PhD, Alberto Ambesi-Impiombato, Marta Sanchez-Martin, PhD, Liang Tong, Adolfo A. Ferrando, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 715.
https://doi.org/10.1182/blood.V130.Suppl_1.715.715
Published: 2017
Journal Articles

The NOTCH1-MYC highway toward T-cell acute lymphoblastic leukemia

Marta Sanchez-Martin, Adolfo Ferrando
Journal: Blood
Blood (2017) 129 (9): 1124–1133.
https://doi.org/10.1182/blood-2016-09-692582
Published: 2017
Journal Articles

Leukemia-Specific Delivery of Mutant NOTCH1 Targeted Therapy

Giovanni Roti, MD PhD, Jun Qi, PhD, Samuel Kitara, Anthony C. Varca, Marta Sanchez-Martin, PhD, Andrew L. Kung, MD PhD, Adolfo A. Ferrando, MD PhD, James E. Bradner, MD, Kimberly Stegmaier, MD
Journal: Blood
Blood (2016) 128 (22): 889.
https://doi.org/10.1182/blood.V128.22.889.889
Published: 2016
Journal Articles

Mutational Landscape, Clonal Evolution Patterns and Role of RAS Mutations in Relapsed Acute Lymphoblastic Leukemia

Koichi Oshima, MD PhD, Hossein Khiabanian, PhD, Ana Carolina da Silva Almeida, PhD, Gannie Tzoneva, PhD, Francesco Abate, PhD, Alberto Ambesi-Impiombato, MD PhD, Marta Sanchez-Martin, PhD, Zachary Carpenter, PhD, Alexander Penson, PhD, Arianne Perez-Garcia, PhD, Cornelia Eckert, PhD, Concepción Nicolás, MD, Milagros Balbin, Maria Luisa Sulis, MD, Motohiro Kato, MD PhD, Katsuyoshi Koh, MD, Maddalena Paganin, Giuseppe Basso, MD, Julie M. Gastier-Foster, PhD, Meenakshi Devidas, PhD, Mignon L. Loh, MD, Renate Kirschner-Schwabe, PhD, Teresa Palomero, PhD, Raul Rabadan, PhD, Adolfo A. Ferrando, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4068.
https://doi.org/10.1182/blood.V128.22.4068.4068
Published: 2016
Journal Articles

Synergistic Targeting of Protein Translation and Inhibition of NOTCH Signaling in T-ALL

Marta Sanchez-Martin, PhD, Alberto Ambesi-Impiombato, MDPhD, Luyao Xu, Yue Qin, Daniel Herranz, PhD, Mukesh Bansal, PhD, Tiziana Girardi, Kim De Keersmaecker, Andrea Califano, PhD, Adolfo A. Ferrando, MD PhD
Journal: Blood
Blood (2015) 126 (23): 3719.
https://doi.org/10.1182/blood.V126.23.3719.3719
Published: 2015
Journal Articles

Tumor-specific HSP90 inhibition as a therapeutic approach in JAK-mutant acute lymphoblastic leukemias

Brief Report
Nicole Kucine, Sachie Marubayashi, Neha Bhagwat, Efthymia Papalexi, Priya Koppikar, Marta Sanchez Martin, Lauren Dong, Marty S. Tallman, Elisabeth Paietta, Kai Wang, Jie He, Doron Lipson, Phil Stephens, Vince Miller, Jacob M. Rowe, Julie Teruya-Feldstein, Charles G. Mullighan, Adolfo A. Ferrando, Andrei Krivtsov, Scott Armstrong, Laura Leung, Stefan O. Ochiana, Gabriela Chiosis, Ross L. Levine, Maria Kleppe
Journal: Blood
Blood (2015) 126 (22): 2479–2483.
https://doi.org/10.1182/blood-2015-03-635821
Published: 2015
Includes: Supplemental data
Journal Articles

Therapeutic targeting of HES1 transcriptional programs in T-ALL

Stephanie A. Schnell, Alberto Ambesi-Impiombato, Marta Sanchez-Martin, Laura Belver, Luyao Xu, Yue Qin, Ryoichiro Kageyama, Adolfo A. Ferrando
Journal: Blood
Blood (2015) 125 (18): 2806–2814.
https://doi.org/10.1182/blood-2014-10-608448
Published: 2015
Includes: Supplemental data
Journal Articles

Patient Derived Xenograft (PDX) Models Recapitulate the Genomic-Driver Composition of Acute Leukemia Samples

Andrei V. Krivtsov, PhD, Xujun Wang, MD, Noushin Rahnamay Farnoud, PhD, Michael Hadler, MSc, Marta Sanchez Martin, Kristina M. Knapp, BS, Eytan M. Stein, Doron Lipson, PhD, Michelle K. Nahas, PhD, Philip J. Stephens, PhD, Eric M Sanford, BS, Kai Wang, MDPhD, Garrett M Frampton, PhD, Tim Brennan, PhD, Geoff A. Otto, PhD, Roman Yelensky, PhD, Vincent Miller, MD, Ross L. Levine, MD, Adolfo A. Ferrando, MD PhD, Scott A. Armstrong, MD PhD
Journal: Blood
Blood (2014) 124 (21): 286.
https://doi.org/10.1182/blood.V124.21.286.286
Published: 2014