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Journal Articles

Exome Sequencing Identifies Glycosylation Defects As a Probable Cause of Immune Thrombotic Thrombocytopenic Purpura

Felipe Massicano, PhD, Elizabeth M. Staley, MD, PhD, Konstantine Halkidis, MD PhD, Nicole K. Kocher, Lance A. Williams, III, MD, Marisa B. Marques, MD, Bryan K. Guillory, MD, Wenjing Cao, MD,PhD, Malay K. Basu, PhD, X. Long Zheng, MD, PhD

Blood (2019) 134 (Supplement_1): 217.

https://doi.org/10.1182/blood-2019-131511

Published: 2019

Journal Articles

Plasma Levels of Histone-DNA Complex and Cell-Free DNA Predict Mortality in Patients with Immune Thrombotic Thrombocytopenic Purpura

Jingrui (Jean) Sui, MD, Konstantine Halkidis, MD PhD, Nicole K. Kocher, Lance A. Williams, III, MD, Radhika Gangaraju, MD, Bryan K. Guillory, MD, Marisa B. Marques, MD, Wenjing Cao, MD,PhD, X. Long Zheng, MD, PhD

Blood (2019) 134 (Supplement_1): 1070.

https://doi.org/10.1182/blood-2019-131585

Published: 2019

Journal Articles

Differential Effect of Rituximab on Relapse-Free Survival in De Novo and Relapsed Immune Thrombotic Thrombocytopenic Purpura in African-American and Caucasian Populations

Blood (2019) 134 (Supplement_1): 90.

https://doi.org/10.1182/blood-2019-129383

Published: 2019

Journal Articles

Disruption of ADAMTS13-Autoantibody Complexes with an ADAMTS13 Spacer Domain As a Potential Therapeutic Strategy for Immune Thrombotic Thrombocytopenic Purpura

Konstantine Halkidis, MD PhD, X. Long Zheng, MD, PhD

Blood (2019) 134 (Supplement_1): 88.

https://doi.org/10.1182/blood-2019-125965

Published: 2019

Journal Articles

Binding of Factor VIII to D'D3 and A2 Domains of Von Willebrand Factor Facilitates Mechanical Unraveling of the A2 Domain

Wenjing Cao, MD,PhD, Wenpeng Cao, Wei Zhang, X. Long Zheng, MD, PhD, Xiaohui (Frank) Zhang, PhD

Blood (2019) 134 (Supplement_1): 95.

https://doi.org/10.1182/blood-2019-125115

Published: 2019

Journal Articles

Longitudinal Assessment of Plasma ADAMTS13 Biomarkers Helps Predict Recurrence of Immune Thrombotic Thrombocytopenic Purpura

Jingrui (Jean) Sui, MD, Wenjing Cao, MD,PhD, Mohammad S. Abdelgawwad, MD, Konstantine Halkidis, MD PhD, Nicole K. Kocher, Bryan K. Guillory, MD, Lance A. Williams, III, MD, Marisa B. Marques, MD, Radhika Gangaraju, MD, X. Long Zheng, MD, PhD

Blood (2019) 134 (Supplement_1): 2456.

https://doi.org/10.1182/blood-2019-126093

Published: 2019

Journal Articles

African American Race Is Associated with Decreased Relapse-Free Survival in Immune Thrombotic Thrombocytopenic Purpura

Blood (2019) 134 (Supplement_1): 1066.

https://doi.org/10.1182/blood-2019-131064

Published: 2019

Journal Articles

Lysine Histone-Induced Thrombocytopenia in Zebrafish Depends on Endothelial Von Willebrand Factor

Liang Zheng, PhD, X. Long Zheng, MD PhD

Blood (2018) 132 (Supplement 1): 3761.

https://doi.org/10.1182/blood-2018-99-117589

Published: 2018

Journal Articles

Active and Ultra-Large Von Willebrand Factor Is Significantly Elevated in Patients with Immune Thrombotic Thrombocytopenic Purpura

Wenjing Cao, PhD, Alicia Veninga, M.Sc., Elizabeth M. Staley, MD, PhD, Adam Miszta, PhD, Nicole Kocher, B.Sc., Lance Williams, III, MD, Marisa B. Marques, MD, Bas de Laat, MD, PhD, X. Long Zheng, MD PhD

Blood (2018) 132 (Supplement 1): 523.

https://doi.org/10.1182/blood-2018-99-117647

Published: 2018

Journal Articles

Evaluation of Pre-Collection Factors and Collection Efficiency Leads to Strong Correlation between Predicted and Actual Peripheral Blood Stem Cell Collection Yields in Multiple Myeloma Patients: A Single Institution Experience

FEI FEI, MD, Daniel Peavey, Mariam Youssef, MD, Sondra Dunn, RN, Terry Slover, RN, Nick Boshell, RN, Marisa B. Marques, MD, Luciano J Costa, MD PhD, X. Long Zheng, MD PhD, Lance Williams, MD

Blood (2018) 132 (Supplement 1): 3349.

https://doi.org/10.1182/blood-2018-99-117320

Published: 2018

Journal Articles

Apolipoprotein B-100 Binds Von Willebrand Factor and Accelerates Its Proteolysis By ADAMTS13 Under Fluidic Shear

Wenjing Cao, PhD, Jingzhi Li, PhD, X. Long Zheng, MD, PhD

Blood (2017) 130 (Supplement 1): 3653.

https://doi.org/10.1182/blood.V130.Suppl_1.3653.3653

Published: 2017

Journal Articles

Platelets Loaded with Recombinant ADAMTS13 Are Efficacious in Inhibiting Arterial Thrombosis Under Flow: A Potential Novel Therapeutic for Acquired TTP

Mohammad Abdelgawwad, MDMSc, Liang Zheng, PhD, X. Long Zheng, MD, PhD

Blood (2017) 130 (Supplement 1): 763.

https://doi.org/10.1182/blood.V130.Suppl_1.763.763

Published: 2017

Journal Articles

Lysine-Histone Triggers Thrombotic Thrombocytopenic Purpura in Zebrafish and Mice

Liang Zheng, PhD, X. Long Zheng, MD, PhD

Blood (2017) 130 (Supplement 1): 294.

https://doi.org/10.1182/blood.V130.Suppl_1.294.294

Published: 2017

Journal Articles

Hydrogen-Deuterium Exchange Plus Mass Spectrometry (HX-MS) Reveals a Novel Mechanism Underlying the pH-Dependent Regulation of ADAMTS13 Activity

Catherine B. Zander, PhD, Vikram G. Pillai, PhD, Leland Mayne, PhD, S. Walter Englander, PhD, X. Long Zheng, MD, PhD

Blood (2017) 130 (Supplement 1): 238.

https://doi.org/10.1182/blood.V130.Suppl_1.238.238

Published: 2017

Journal Articles

Platelet-Delivered Recombinant ADAMTS13 Inhibits Platelet Adhesion and Aggregation on Collagen Surface Under Flow in the Presence of Autoantibodies from Acquired Thrombotic Thrombocytopenic Purpura

Mohammad S. Abdelgawwad, MD, M.Sc., Jenny K. McDaniel, MD, Wenjing Cao, MD, PhD, Huy P. Pham, MD, M.P.H., Lance A. Williams, MD, X. Long Zheng, MD, PhD

Blood (2016) 128 (22): 1374.

https://doi.org/10.1182/blood.V128.22.1374.1374

Published: 2016

Journal Articles

Distal Carboxyl-Terminal Domains of ADAMTS13 Determine Its Substrate Specificity

Wenjing Cao, MD, PhD, Catherine B. Zander, PhD, X. Long Zheng, MD, PhD

Blood (2016) 128 (22): 1383.

https://doi.org/10.1182/blood.V128.22.1383.1383

Published: 2016

Journal Articles

Synthetic Partially Reduced Human Neutrophil Peptide (HNP)-1 Inhibits Platelet Adhesion and Aggregation on Von Willebrand Factor-Collagen Surfaces Under Arterial Shear Stress through a Disulfide Bond Reduction Mechanism

Jenny K. McDaniel, MD, Khalil Bdeir, PhD, Douglas B. Cines, MD, X. Long Zheng, MD, PhD

Blood (2016) 128 (22): 3722.

https://doi.org/10.1182/blood.V128.22.3722.3722

Published: 2016

Journal Articles

Predictors for in-Hospital Mortality in Patients with Autoimmune Thrombotic Thrombocytopenia Purpura (TTP): A Single Center Experience

Huy P. Pham, MD, M.P.H., Wenjing Cao, MD, PhD, Lance A. Williams, MD, Alexander Z. Feldman, MD, Rance C. Siniard, MD, Robin G. Lorenz, MD, PhD, Dheeraj Raju, PhD, Marisa B. Marques, MD, PhD, X. Long Zheng, MD, PhD

Blood (2016) 128 (22): 3853.

https://doi.org/10.1182/blood.V128.22.3853.3853

Published: 2016

Journal Articles

Plasma ADAMTS13 Activity Associates with Injury Severity in Pediatric Trauma Patients

Jenny K. McDaniel, MD, Ilan I Maizlin, MD, Michelle C. Shroyer, M.P.H., Morgan E. Banks, Jean-Francois Pittet, MD, X. Long Zheng, MD, PhD, Robert T. Russell, MD, M.P.H.

Blood (2016) 128 (22): 3777.

https://doi.org/10.1182/blood.V128.22.3777.3777

Published: 2016

Journal Articles

ADAMTS13 -/- zebrafish Model Created By Crispr/Cas Reveals a Novel Role of ADAMTS13 in Vascular Development and Prothrombotic Phenotype

Liang Zheng, PhD, X. Long Zheng, MD, PhD

Blood (2016) 128 (22): 1446.

https://doi.org/10.1182/blood.V128.22.1446.1446

Published: 2016

NARROW

Exome Sequencing Identifies Glycosylation Defects As a Probable Cause of Immune Thrombotic Thrombocytopenic Purpura

Plasma Levels of Histone-DNA Complex and Cell-Free DNA Predict Mortality in Patients with Immune Thrombotic Thrombocytopenic Purpura

Differential Effect of Rituximab on Relapse-Free Survival in De Novo and Relapsed Immune Thrombotic Thrombocytopenic Purpura in African-American and Caucasian Populations

Disruption of ADAMTS13-Autoantibody Complexes with an ADAMTS13 Spacer Domain As a Potential Therapeutic Strategy for Immune Thrombotic Thrombocytopenic Purpura

Binding of Factor VIII to D'D3 and A2 Domains of Von Willebrand Factor Facilitates Mechanical Unraveling of the A2 Domain

Longitudinal Assessment of Plasma ADAMTS13 Biomarkers Helps Predict Recurrence of Immune Thrombotic Thrombocytopenic Purpura

African American Race Is Associated with Decreased Relapse-Free Survival in Immune Thrombotic Thrombocytopenic Purpura

Lysine Histone-Induced Thrombocytopenia in Zebrafish Depends on Endothelial Von Willebrand Factor

Active and Ultra-Large Von Willebrand Factor Is Significantly Elevated in Patients with Immune Thrombotic Thrombocytopenic Purpura

Evaluation of Pre-Collection Factors and Collection Efficiency Leads to Strong Correlation between Predicted and Actual Peripheral Blood Stem Cell Collection Yields in Multiple Myeloma Patients: A Single Institution Experience

Apolipoprotein B-100 Binds Von Willebrand Factor and Accelerates Its Proteolysis By ADAMTS13 Under Fluidic Shear

Platelets Loaded with Recombinant ADAMTS13 Are Efficacious in Inhibiting Arterial Thrombosis Under Flow: A Potential Novel Therapeutic for Acquired TTP

Lysine-Histone Triggers Thrombotic Thrombocytopenic Purpura in Zebrafish and Mice

Hydrogen-Deuterium Exchange Plus Mass Spectrometry (HX-MS) Reveals a Novel Mechanism Underlying the pH-Dependent Regulation of ADAMTS13 Activity

Platelet-Delivered Recombinant ADAMTS13 Inhibits Platelet Adhesion and Aggregation on Collagen Surface Under Flow in the Presence of Autoantibodies from Acquired Thrombotic Thrombocytopenic Purpura

Distal Carboxyl-Terminal Domains of ADAMTS13 Determine Its Substrate Specificity

Synthetic Partially Reduced Human Neutrophil Peptide (HNP)-1 Inhibits Platelet Adhesion and Aggregation on Von Willebrand Factor-Collagen Surfaces Under Arterial Shear Stress through a Disulfide Bond Reduction Mechanism

Predictors for in-Hospital Mortality in Patients with Autoimmune Thrombotic Thrombocytopenia Purpura (TTP): A Single Center Experience

Plasma ADAMTS13 Activity Associates with Injury Severity in Pediatric Trauma Patients

ADAMTS13 -/- zebrafish Model Created By Crispr/Cas Reveals a Novel Role of ADAMTS13 in Vascular Development and Prothrombotic Phenotype

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American Society of Hematology

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ASH Publications

American Society of Hematology

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