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Journal Articles

Safety and Efficacy of FT522, a First-in-Class, Multi-Antigen Targeted, Off-the-Shelf, iPSC-Derived CD19 CAR NK Cell Therapy with Alloimmune Defense Receptor (ADR) in Relapsed/Refractory B-Cell Lymphoma

Veronika Bachanova, Abhinav Deol, Taha Mahdi Salih Al-Juhaishi, Premal D. Lulla, Michael T. Byrne, Carol Wong, Cara Bickers, Trever Greene, Lilly Wong, Bertha Villa, Deepa Patel, Bahram Bob Valamehr, Rebecca Elstrom, Matthew Lunning
Journal: Blood
Blood (2024) 144 (Supplement 1): 6543.
https://doi.org/10.1182/blood-2024-198684
Published: 2024
Journal Articles

Next-Generation Off-the-Shelf CAR T-Cell Therapy Developed to Eliminate a Broad Spectrum of Pathogenic Cells in Hematological Diseases in the Absence of Conditioning Chemotherapy

John Goulding, Mark Jelcic, Daniel Morales-Mantilla, John Reiser, Alison O'Connor, Rina Mbofung, Alan Williams, Dan Lu, Bi-Huei Yang, Alma Gutierrez, Miguel Meza, Yijia Pan, Jonatan Tuncel, Bryan Hancock, Sean Sherman, Alec Witty, Eigen Peralta, Martin Hosking, Lilly Wong, Tom Lee, Jode Goodridge, Bahram Valamehr
Journal: Blood
Blood (2024) 144 (Supplement 1): 4801.
https://doi.org/10.1182/blood-2024-209465
Published: 2024
Journal Articles

FT538, iPSC-Derived NK Cells Are Potent Inducers of Apoptosis in AML Cells and Their Effect Is Synergistic in Combination with Approved Therapeutic Strategies

Amanda Eckstrom, Anudishi Tyagi, Maryam Siddiqui, Sajid Mahmood, Lilly Wong, Bahram Bob Valamehr, Naval Daver, Venkata Lokesh Battula
Journal: Blood
Blood (2023) 142 (Supplement 1): 4817.
https://doi.org/10.1182/blood-2023-187192
Published: 2023
Journal Articles

Interim Phase I Clinical Data of FT819-101, a Study of the First-Ever, Off-the-Shelf, iPSC-Derived TCR-Less CD19 CAR T-Cell Therapy for Patients with Relapsed/Refractory B-Cell Malignancies

Amitkumar Mehta, Umar Farooq, Andy Chen, Joseph P. McGuirk, Thomas Ly, Lilly Wong, Sarah Cooley, Bahram Valamehr, Rebecca Elstrom, Yu-Waye Chu, Jae H. Park
Journal: Blood
Blood (2022) 140 (Supplement 1): 4577–4578.
https://doi.org/10.1182/blood-2022-167194
Published: 2022
Journal Articles

Interim Phase I Clinical Data of FT576 As Monotherapy and in Combination with Daratumumab in Subjects with Relapsed/Refractory Multiple Myeloma

Binod Dhakal, Jesus G. Berdeja, Tara Gregory, Thomas Ly, Cara Bickers, Xingyue Zong, Lilly Wong, Jode P. Goodridge, Sarah Cooley, Bahram Valamehr, Yu-Waye Chu, John Byon, Rafat Abonour
Journal: Blood
Blood (2022) 140 (Supplement 1): 4586–4587.
https://doi.org/10.1182/blood-2022-166994
Published: 2022
Journal Articles

iPSC-Derived CD38-Null NK Cells in Combination with CD38-Targeted Antibody: A Dual Therapeutic Strategy to Enable ADCC and Eliminate Host Immune Cells in Multiple Myeloma

Rina M Mbofung, Xingyue Zong, Erika Varady, Alan M Williams, Ken L Hayama, Yijia Pan, Sushil Devkota, Brian Groff, Miguel Meza, Thomas Dailey, Tom Lee, Lilly Wong, Sarah Cooley, Ryan Bjordahl, Jode P Goodridge, Bahram Valamehr
Journal: Blood
Blood (2022) 140 (Supplement 1): 7388–7389.
https://doi.org/10.1182/blood-2022-169817
Published: 2022
Journal Articles

Mezigdomide (CC-92480), a Novel Cereblon E3 Ligase Modulator, Induces Vulnerability of Multiple Myeloma Cells to T-Cell-Mediated Killing

Bonny Gaffney, Yu Shi, Petrus de Jong, Manuel Sanchez, Celia Fontanillo, Antonia Lopez-Girona, Isaac W. Boss, Antonina Kurtova, Soraya Carrancio, Lilly Wong, Daniel W. Pierce
Journal: Blood
Blood (2022) 140 (Supplement 1): 7108–7109.
https://doi.org/10.1182/blood-2022-157939
Published: 2022
Journal Articles

A Phase I Study of FT538, an Off-the-Shelf, Multiplexed-Engineered, iPSC-Derived NK Cell Therapy in Combination with Daratumumab in Relapsed/Refractory Multiple Myeloma

Mark Juckett, Sham Mailankody, Alireza Eghtedar, Cara Bickers, Xingyue Zong, Lilly Wong, Thomas Ly, John Byon, Sarah Cooley, Bahram Valamehr, Yu-Waye Chu, Ravi Vij
Journal: Blood
Blood (2022) 140 (Supplement 1): 10327–10328.
https://doi.org/10.1182/blood-2022-166728
Published: 2022
Journal Articles

Phase I Study of FT516, an Off-the-Shelf iPSC-Derived NK Cell Therapy, in Combination with Rituximab in Patients with Relapsed/Refractory B-Cell Lymphoma

Krish Patel, Veronika Bachanova, Aaron M Goodman, John M. Pagel, Kelly Griffis, Marlisa Anderson, Siminder Atwal, Cara Bickers, Peter Szabo, Lilly Wong, Yu-Waye Chu, Rebecca Elstrom, Paolo Strati
Journal: Blood
Blood (2021) 138 (Supplement 1): 3873.
https://doi.org/10.1182/blood-2021-151520
Published: 2021
Journal Articles

Safety and Efficacy of FT596, a First-in-Class, Multi-Antigen Targeted, Off-the-Shelf, iPSC-Derived CD19 CAR NK Cell Therapy in Relapsed/Refractory B-Cell Lymphoma

Veronika Bachanova, Armin Ghobadi, Krish Patel, Jae H Park, Ian W. Flinn, Prutha Shah, Carol Wong, Cara Bickers, Peter Szabo, Lilly Wong, Bahram Valamehr, Siminder Atwal, Yu-Waye Chu, Rebecca Elstrom, Paolo Strati
Journal: Blood
Blood (2021) 138 (Supplement 1): 823.
https://doi.org/10.1182/blood-2021-151185
Published: 2021
Journal Articles

Off-the-Shelf, Multiplexed-Engineered iPSC-Derived NK Cells Mediate Potent Multi-Antigen Targeting of B-Cell Malignancies with Reduced Cytotoxicity Against Healthy B Cells

Frank Cichocki, Jode P Goodridge, Ryan Bjordahl, Svetlana Gaidarova, Sajid Mahmood, Ramzey Abujarour, Zachary Davis, Hongbo Wang, Katie Tuininga, Behiye Kodal, Martin Felices, Paul Rogers, Greg Bonello, Janel Huffman, Thomas Dailey, Tom Lee, Peter Szabo, Lilly Wong, Sarah Cooley, Bahram Valamehr, Jeffrey S. Miller
Journal: Blood
Blood (2021) 138 (Supplement 1): 407.
https://doi.org/10.1182/blood-2021-148654
Published: 2021
Journal Articles

Dose- and Schedule-Dependent Immunomodulatory Effects of the Novel Celmod Agent CC-92480 in Patients with Relapsed/Refractory Multiple Myeloma

Lilly Wong, Manisha Lamba, María Dolores Jiménez Nuñez, Daniel Bauer, Paul G. Richardson, MD, Nizar J. Bahlis, MD, Annette J. Vangsted, Karthik Ramasamy, Suzanne Trudel, Joaquín Martínez-Lopez, María-Victoria Mateos, Paula Rodriguez-Otero, MD PhD, Sagar Lonial, MD FACP, Rakesh Popat, Albert Oriol, Chatchada Karanes, Robert Z. Orlowski, MDPhD, Jesus G. Berdeja, MD, Michael Pourdehnad, Daniel W. Pierce
Journal: Blood
Blood (2020) 136 (Supplement 1): 47–48.
https://doi.org/10.1182/blood-2020-137161
Published: 2020
Journal Articles

Preclinical and Translational Support for Clinical Development of Iberdomide in Combination with Proteasome Inhibitors: Mechanism of Synergy in Clinical Trial CC-220-MM-001

Michael Amatangelo, Chad Bjorklund, Jian Kang, Archana Mukhopadhyay, María Dolores Jiménez Nuñez, Lilly Wong, William Pierceall, Sagar Lonial, MD FACP, Niels W.C.J. van de Donk, Rakesh Popat, Sundar Jagannath, MD, Jeffrey Zonder, Monique C. Minnema, Albert Oriol, Jeremy Larsen, Ashraf Z. Badros, MD, Paula Rodriguez-Otero, MD PhD, Pieter Sonneveld, MD PhD, Tuong Vi Nguyen, Kevin Hong, April Sorrell, Anjan Thakurta
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
https://doi.org/10.1182/blood-2020-137710
Published: 2020
Journal Articles

CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immunomodulatory Activity Against Sensitive and Resistant Multiple Myeloma Cells

Antonia Lopez-Girona, Courtney G. Havens, Gang Lu, Emily Rychak, Derek Mendy, Bonny Gaffney, Christine Surka, Chin-Chun Lu, Mary Matyskiela, Gody Khambatta, Lilly Wong, Joshua Hansen, Daniel W. Pierce, Brian E. Cathers, James Carmichael
Journal: Blood
Blood (2019) 134 (Supplement_1): 1812.
https://doi.org/10.1182/blood-2019-124338
Published: 2019
Journal Articles

CC-92480, a Novel Cereblon E3 Ligase Modulator, Is Synergistic with Dexamethasone, Bortezomib, and Daratumumab in Multiple Myeloma

Lilly Wong, Rama Krishna Narla, Jim Leisten, Daniel Bauer, Matthew Groza, Bonny Gaffney, Courtney G. Havens, Justin Choi, Jack Houston, Antonia Lopez-Girona, Joshua Hansen, Brian E. Cathers, James Carmichael, Daniel W. Pierce
Journal: Blood
Blood (2019) 134 (Supplement_1): 1815.
https://doi.org/10.1182/blood-2019-124345
Published: 2019