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Journal Articles

A weekly low-dose regimen of decitabine and venetoclax is efficacious and less myelotoxic in a racially diverse cohort

Clinical Trials & Observations
Mendel Goldfinger, Ioannis Mantzaris, Aditi Shastri, Yogen Saunthararajah, Kira Gritsman, R. Alejandro Sica, Noah Kornblum, Nishi Shah, David Levitz, Bradley Rockwell, Lauren C. Shapiro, Ridhi Gupta, Kith Pradhan, Xiaonan Xue, Anne Munoz, Aradhika Dhawan, Karen Fehn, Monica Comas, Jhannine Alyssa Verceles, Brian A. Jonas, Suman Kambhampati, Yang Shi, Ira Braunschweig, Dennis L. Cooper, Marina Konopleva, Eric J. Feldman, Amit Verma
Journal: Blood
Blood (2024) 144 (22): 2360–2363.
https://doi.org/10.1182/blood.2024025834
Published: 2024
Includes: Supplemental data
Journal Articles

Efficacy of Cladribine, Low-Dose Cytarabine, and Venetoclax in Relapsed/Refractory Acute Myeloid Leukemia in a High-Risk Ethnically Diverse Cohort

John Yan, Josette Kamel, Amit Verma, Eric J. Feldman, Dennis L Cooper, Lauren Shapiro, Ridhi Gupta, Nishi Shah, Noah Kornblum, David Levitz, R. Alejandro Sica, Kira Gritsman, Aditi Shastri, Ioannis Mantzaris, Mendel Goldfinger, Marina Konopleva
Journal: Blood
Blood (2024) 144 (Supplement 1): 5966.
https://doi.org/10.1182/blood-2024-212222
Published: 2024
Journal Articles

Current Trends of Severe Renal Impairment in Newly Diagnosed Multiple Myeloma: A Single-Center Experience in a Low Socio-Economic Population

M Bakri Hammami, Jeevan Shivakumar, Nina Samuel, Rajvi Gor, Mendel Goldfinger, Noah Kornblum, Lauren Shapiro, Aditi Shastri, Ridhi Gupta, David Levitz, Marina Konopleva, Eric J. Feldman, Kira Gritsman, R. Alejandro Sica, Ioannis Mantzaris, Amit Verma, Dennis L Cooper, Nishi Shah
Journal: Blood
Blood (2024) 144 (Supplement 1): 6999.
https://doi.org/10.1182/blood-2024-208770
Published: 2024
Journal Articles

Neurotoxicity of Axicabtagene Ciloleucel in an Ethnically Diverse, Real-World Cohort

Elizabeth Zeldin, Samantha J Cheng, Ryann Quinn, Kith Pradhan, Mendel Goldfinger, Ioannis Mantzaris, Nishi Shah, Aditi Shastri, Noah Kornblum, Dennis L Cooper, Ridhi Gupta, Lauren Shapiro, Kira Gritsman, Ahmed Abbasi, Amit Verma, Ira Braunschweig, Katharine McNeill, Mark Milstein, R. Alejandro Sica
Journal: Blood
Blood (2024) 144 (Supplement 1): 7201.
https://doi.org/10.1182/blood-2024-201715
Published: 2024
Journal Articles

WU-CART-007 (WT-7) Is an Effective Treatment for Adolescent Patients with Relapsed or Refractory (R/R) T-Cell Acute Lymphoblastic Leukemia/ Lymphoblastic Lymphoma (T-ALL/LBL) - Subgroup Analysis of WU-CART-007 1001

Shannon L. Maude, Deepa Bhojwani, Alan S. Wayne, Friso G. J. Calkoen, André Baruchel, Christian Michel Zwaan, Michael P. Rettig, Ouiam Bakkacha, Justo L. Gonzalez, Deborah Masters, Maria del Rosario, Laura Simpson, Preeta Dasgupta, Tony Wu, Stephen Moran, Michael Munroe, Haley Irons, Eileen McNulty, Matthew L. Cooper, Alexander Hamil, John Muth, Brett Ramsey, Jan K Davidson-Moncada, John F. DiPersio
Journal: Blood
Blood (2024) 144 (Supplement 1): 3461.
https://doi.org/10.1182/blood-2024-201998
Published: 2024
Journal Articles

Impact of Age and Race on Survival in Adult T-Cell Leukemia/Lymphoma in the United States

Madeline G D'Agostino, B. Hilda Ye, Murali Janakiram, Dennis L Cooper, Ioannis Mantzaris, Aditi Shastri, Mendel Goldfinger, Noah Kornblum, Nishi Shah, Amit Verma, Lauren Shapiro, Ridhi Gupta, Yang Shi, Yanhua Wang, Alyssa De Castro, John X Wei, R. Alejandro Sica
Journal: Blood
Blood (2024) 144 (Supplement 1): 7732.
https://doi.org/10.1182/blood-2024-208561
Published: 2024
Journal Articles

Post-Transplantation Cyclophosphamide and Abatacept Graft-Versus-Host-Disease Prophylaxis Shows Improved Outcomes in North American Adult T-Cell Leukemia/Lymphoma

Julie Nguyen, Abdul-Hamid Bazarbachi, Kith Pradhan, John Yan, Emma Cordover, Daniel K Reef, Riya Patel, Rama Al Hamed, Astha Thakkar, Shafia Rahman, Diego Adrianzen Herrera, Ryann Quinn, Alyssa de Castro, Kailyn Gillick, Jennat Mustafa, Fariha Khatun, Amanda Lombardo, Latoya S Townsend, Michelly Abreu, Nicole Chambers, Richard Elkind, Yang Shi, Yanhua Wang, Olga Derman, Kira Gritsman, Ulrich Steidl, Mendel Goldfinger, Noah Kornblum, Aditi Shastri, Ioannis Mantzaris, Lizamarie Bachier Rodriguez, Brittany Moavero, Jhannine Verceles, Angela Czavar, Lauren Shapiro, Trent Wang, Juan Carlos Ramos, Nishi Shah, Ridhi Gupta, Marina Konopleva, Ira Braunschweig, Amit Verma, B. Hilda Ye, Murali Janakiram, Dennis L Cooper, R. Alejandro Sica
Journal: Blood
Blood (2024) 144 (Supplement 1): 7367.
https://doi.org/10.1182/blood-2024-207521
Published: 2024
Journal Articles

Mogamulizumab Shows Significant Activity with Tolerable Toxicity in a Real-World North American Adult T-Cell Leukemia/Lymphoma (ATLL) Cohort

Emma Cordover, Kith Pradhan, Latoya S. Townsend, Mendel Goldfinger, Ioannis Mantzaris, Nishi Shah, Aditi Shastri, Noah Kornblum, Dennis L Cooper, Ridhi Gupta, Lauren Shapiro, Kira Gritsman, Marina Konopleva, Alyssa de Castro, Roy Browne, Salvatore Lia, Amit Verma, Ali Bazarbachi, B. Hilda Ye, Murali Janakiram, R. Alejandro Sica
Journal: Blood
Blood (2024) 144 (Supplement 1): 6418.
https://doi.org/10.1182/blood-2024-210619
Published: 2024
Journal Articles

Metronomic Low-Dose Regimen of Decitabine and Venetoclax Is Safe and Efficacious for Chronic Myelomonocytic Leukemia

Bradley Rockwell, Ioannis Mantzaris, Aditi Shastri, Kira Gritsman, R. Alejandro Sica, Noah Kornblum, Nishi Shah, David Levitz, Lauren Shapiro, Ridhi Gupta, Annemarie Munoz, Aradhika Dhawan, Karen Fehn, Monica Comas, Jhannine Verceles, Dennis L Cooper, Marina Konopleva, Eric J. Feldman, Amit Verma, Mendel Goldfinger
Journal: Blood
Blood (2024) 144 (Supplement 1): 6723.
https://doi.org/10.1182/blood-2024-211307
Published: 2024
Journal Articles

Assessing the Utility of Interim Bone Marrow Results in Acute Myeloid Leukemia Induction

Mumtu Lalla, Matan Uriel, Mendel Goldfinger, Aditi Shastri, Kira Gritsman, Nishi Shah, Noah Kornblum, Lauren Shapiro, R. Alejandro Sica, Annemarie Munoz, Nicole Chambers, Aradhika Dhawan, Karen Fehn, Balda Tirone, Lamisha Shah, Shaunmonique Clark, Amit Verma, Mimi Kim, Dennis L Cooper, Eric J. Feldman, Marina Konopleva, Ioannis Mantzaris
Journal: Blood
Blood (2024) 144 (Supplement 1): 6175.
https://doi.org/10.1182/blood-2024-208911
Published: 2024
Journal Articles

A Phase 1 Study Investigating the Safety and Efficacy of Danvatirsen As Monotherapy Followed By Combination with Venetoclax in Patients with Relapsed/Refractory MDS and AML

Aditi Shastri, Mendel Goldfinger, Ioannis Mantzaris, Guillermo Garcia-Manero, Tapan M. Kadia, Jing Ning, Balda Tirone, Rikin Gandhi, Farhad Ravandi, Naveen Pemmaraju, Guillermo Montalban-Bravo, Annemarie Munoz, Michelle Golez, Lianchun Xiao, Kith Pradhan, Karen Fehn, Lamisha Shah, Hui Zhang, Samarpana Chakraborty, Eric J. Feldman, Nicholas J. Short, Jayastu Senapati, Dennis L Cooper, Alejandro Sica, Noah Kornblum, Lauren Shapiro, Nishi Shah, Susan MacIntyre, Ulrich Steidl, Amit Verma, Kira Gritsman, Andrew Denker, Marina Konopleva, Naval Daver
Journal: Blood
Blood (2024) 144 (Supplement 1): 4265.5.
https://doi.org/10.1182/blood-2024-208998
Published: 2024
Journal Articles

Impact of Patient and Donor Factors on Successful Hematopoietic Stem Cell Transplantation for Acute T-Cell Leukemia/Lymphoma Patients in an Underserved Minority Population

John Yan, Parth Patel, Simran Arjani, Eliot A Rapoport, Brittany Moavero, Jhannine Verceles, Angela Czavar, Emma Cordover, Julie Nguyen, Kira Gritsman, Noah Kornblum, Aditi Shastri, Ioannis Mantzaris, Nishi Shah, Ridhi Gupta, Marina Konopleva, Amit Verma, Eric J. Feldman, Dennis L Cooper, Mendel Goldfinger, R. Alejandro Sica, Lauren Shapiro
Journal: Blood
Blood (2024) 144 (Supplement 1): 4443.
https://doi.org/10.1182/blood-2024-211956
Published: 2024
Journal Articles

WU-CART-007 (WT-7), an Allogeneic CAR T-Cell Targeting CD7 in Relapsed/Refractory (R/R) T-Cell Acute Lymphoblastic Leukemia/Lymphoma (T-ALL/LBL): Phase 2 Results

Armin Ghobadi, Ibrahim Aldoss, Shannon L. Maude, Deepa Bhojwani, Rawan Faramand, Ashish Bajel, Friso G. J. Calkoen, Alan S. Wayne, Bhagirathbhai Dholaria, Ryan J Mattison, Anita W. Rijneveld, Christian Michel Zwaan, André Baruchel, Nicolas Boissel, Michael P. Rettig, Maria del Rosario, Stephen Moran, Alexander Hamil, Ouiam Bakkacha, Deborah Masters, Justo L. Gonzalez, Michael Munroe, Laura Simpson, Preeta Dasgupta, Tony Wu, John Muth, Haley Irons, Brett Ramsey, Eileen McNulty, Matthew L. Cooper, Jan K Davidson-Moncada, John F. DiPersio
Journal: Blood
Blood (2024) 144 (Supplement 1): 3450.
https://doi.org/10.1182/blood-2024-202005
Published: 2024
Journal Articles

Venetoclax Combined with “7+3” Induction Chemotherapy Induces High MRD-Negative Response Rates in Newly Diagnosed AML Patients Fit for Intensive Chemotherapy across Ages

Ioannis Mantzaris, Matan Uriel, Mendel Goldfinger, Aditi Shastri, Nishi Shah, Kira Gritsman, Noah Kornblum, Lauren Shapiro, R. Alejandro Sica, Annemarie Munoz, Nicole Chambers, Aradhika Dhawan, Karen Fehn, Balda Tirone, Lamisha Shah, Shaunmonique Clark, Mimi Kim, Chenxin Zhang, Dennis L Cooper, Amit Verma, Marina Konopleva, Eric J. Feldman
Journal: Blood
Blood (2024) 144 (Supplement 1): 57.
https://doi.org/10.1182/blood-2024-211685
Published: 2024
Journal Articles

Venetoclax Alone or in Combination Shows Promising Activity in Preclinical Models and Clinical Cases of Relapsed/Refractory North American Adult T-Cell Leukemia Lymphoma

Ankit Tanwar, Emma Cordover, Shikhar Sharma, Zixuan Tong, Kith Pradhan, Latoya S Townsend, Ioannis Mantzaris, Mendel Goldfinger, Nishi Shah, Aditi Shastri, Noah Kornblum, Dennis L Cooper, Ridhi Gupta, Simon Zhen, Nechama Dreyfus, Julie Nguyen, Lauren Shapiro, Eric J. Feldman, Ira Braunschweig, Beth McLellan, Alyssa de Castro, Xingxing Zang, Ali Bazarbachi, Murali Janakiram, Erik Guillen, Gregoire Lauvau, Eric Liu, Kira Gritsman, B. Hilda Ye, Amit Verma, Marina Konopleva, R. Alejandro Sica
Journal: Blood
Blood (2024) 144 (Supplement 1): 2791.
https://doi.org/10.1182/blood-2024-206160
Published: 2024
Journal Articles

WUC007-03: A Phase 2 Study of Anti-CD7 Allogenic CAR-T Cells (WT-7) in Patients with Relapsed/Refractory (R/R) T-Cell Acute Lymphoblastic Leukemia (T-ALL)/Lymphoblastic Lymphoma (LBL)

Armin Ghobadi, Shannon L. Maude, Ibrahim Aldoss, Ashish Bajel, Ryan J Mattison, Deepa Bhojwani, Alan S. Wayne, Rawan Faramand, Bhagirathbhai Dholaria, Seong Lin Khaw, Anita W. Rijneveld, Friso G. J. Calkoen, Christian Michel Zwaan, André Baruchel, Nicolas Boissel, Andrej Lissat, Stefan Schwartz, Peter Bader, Fabian Lang, Michael P. Rettig, Haley Irons, Brett Ramsey, John Muth, Laura Simpson, Preeta Dasgupta, Stephen Moran, Michael Munroe, Maria del Rosario, Tony Wu, Ouiam Bakkacha, Justo L. Gonzalez, Deborah Masters, Alexander Hamil, Eileen McNulty, Matthew L. Cooper, Jan K Davidson-Moncada, John F. DiPersio
Journal: Blood
Blood (2024) 144 (Supplement 1): 7225.
https://doi.org/10.1182/blood-2024-201825
Published: 2024
Journal Articles

Promising Safety and Efficacy Data for Peginterferon Alfa-2a (PEG-IFN) and Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy) in a North American Adult T-Cell Leukemia Lymphoma (NA-ATLL) Cohort of Patients

Nechama Dreyfus, Emma Cordover, Kith Pradhan, Latoya S Townsend, Mendel Goldfinger, Ioannis Mantzaris, Nishi Shah, Aditi Shastri, Noah Kornblum, Dennis L Cooper, Ridhi Gupta, Lauren Shapiro, Kira Gritsman, Marina Konopleva, Beth McLellan, Simon Zhen, Alyssa de Castro, Salvatore Lia, Virleny Garcia, Roy Browne, Eric Meyerowitz, Yoram Puius, Margaret McCort, Yang Shi, Yanhua Wang, Amit Verma, B. Hilda Ye, Murali Janakiram, Abdul-Hamid Bazarbachi, R. Alejandro Sica
Journal: Blood
Blood (2024) 144 (Supplement 1): 3067.
https://doi.org/10.1182/blood-2024-208199
Published: 2024
Journal Articles

Assessing the Performance of the Iceland Screens, Treats, or Prevents Multiple Myeloma (iStopMM) Model in a Multicultural Bronx Cohort: Implications for Monoclonal Gammopathy of Undetermined Significance (MGUS) Risk Stratification

Rajvi Gor, Jeevan Shivakumar, Pallavi Surana, John X Wei, Irina Murakhovskaya, Mendel Goldfinger, Noah Kornblum, Lauren Shapiro, Aditi Shastri, Ridhi Gupta, David Levitz, Marina Konopleva, Eric J. Feldman, Kira Gritsman, R. Alejandro Sica, Ioannis Mantzaris, Amit Verma, Dennis L Cooper, Murali Janakiram, Nishi Shah
Journal: Blood
Blood (2024) 144 (Supplement 1): 3307.
https://doi.org/10.1182/blood-2024-201590
Published: 2024
Journal Articles

Efficacy and Safety of Teclistamab in Relapsed Refractory Multiple Myeloma: Long-Term Follow-up from a Real World Multi-Institutional Cohort

Metodi Balev, Nishi Shah, Mansi R. Shah, Anannya Patwari, Aniko Szabo, Anita D'Souza, Asis Shrestha, Binod Dhakal, Danny Luan, Dennis L Cooper, Frits van Rhee, Heloise Cheruvalath, Jorge Monge, Mark Forsberg, Maurizio Zangari, Sharmilan Thanendrarajan, Vineel Bhatlapenumarthi, Samer Al-Hadidi, Suzanne Lentzsch, Divaya Bhutani, Rajshekhar Chakraborty, Carolina Schinke, Meera Mohan
Journal: Blood
Blood (2024) 144 (Supplement 1): 3781.
https://doi.org/10.1182/blood-2024-203609
Published: 2024
Journal Articles

Teclistamab in Relapsed Refractory Multiple Myeloma: Multi-Institutional Real-World Study

Meera Mohan, Nishi Shah, Danny Luan, Jorge Monge, Mark Forsberg, Vineel Bhatlapenumarthi, Metodi Balev, Anannya Patwari, Heloise Cheruvalath, Divaya Bhutani, Sharmilan Thanendrarajan, Binod Dhakal, Maurizio Zangari, Samer Al Hadidi, Dennis L Cooper, Suzanne Lentzsch, Frits van Rhee, Anita D'Souza, Aniko Szabo, Carolina Schinke, Rajshekhar Chakraborty
Journal: Blood
Blood (2023) 142 (Supplement 1): 545.
https://doi.org/10.1182/blood-2023-174875
Published: 2023