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Kimberly Straley
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Journal Articles

IDH2 mutation-induced histone and DNA hypermethylation is progressively reversed by small-molecule inhibition

Andrew Kernytsky, Fang Wang, Erica Hansen, Stefanie Schalm, Kimberly Straley, Camelia Gliser, Hua Yang, Jeremy Travins, Stuart Murray, Marion Dorsch, Sam Agresta, David P. Schenkein, Scott A. Biller, Shinsan M. Su, Wei Liu, Katharine E. Yen
Journal: Blood
Blood (2015) 125 (2): 296–303.
https://doi.org/10.1182/blood-2013-10-533604
Published: 2015
Includes: Supplemental data
Journal Articles

Diagnostic Features and 2-Hydroxyglutarate (2-HG) Levels Among Acute Myeloid Leukemia (AML) Patients with and without Isocitrate Dehydrogenase (IDH) Mutations

Andrew M. Brunner, MD, Seth A. Wander, MD PhD, Donna Neuberg, ScD, Hossein Sadrzadeh, Karen K. Ballen, MD, Philip C. Amrein, MD, Eyal C. Attar, MD, Yi-Bin Chen, MD, Ashley M. Perry, Meghan Burke, Regina Silver, Sophia Adamia, Katharine Yen, Hua Yang, Kimberly Straley, Sam Agresta, Darrell R. Borger, PhD, Anthony J. Iafrate, MD PhD, Richard M. Stone, MD, Amir T. Fathi, MD
Journal: Blood
Blood (2014) 124 (21): 1045.
https://doi.org/10.1182/blood.V124.21.1045.1045
Published: 2014
Journal Articles

Serum 2-Hydroxyglutarate Levels Predict Isocitrate Dehydrogenase Mutations and Clinical Outcome in Acute Myeloid Leukemia.

Courtney D. DiNardo, MD, Ross L. Levine, Kathleen J Propert, ScD, Alison W. Loren, MD, Elisabeth Paietta, PhD, Zhouxin Sun, PhD, Kimberly Straley, BS, Katharine Yen, Jay P. Patel, Samuel Agresta, MD, Omar Abdel-Wahab, Alexander E Perl, MD, Hugo F Fernandez, MD, David Margolis, MD, MSCE, Martin S. Tallman, MD, Selina M. Luger, MD, Martin Carroll, MD
Journal: Blood
Blood (2012) 120 (21): 2481.
https://doi.org/10.1182/blood.V120.21.2481.2481
Published: 2012
Journal Articles

Mutation Selective IDH Inhibitors Mediate Histone and DNA Methylation Changes

Katharine Yen, Fang Wang, Stefanie Schalm, Erica Hansen, Kimberly Straley, BS, Andrew Kernytsky, Sung Choe, Wei Liu, Janeta Popovici-Muller, Jeremy Travins, Hua Yang, Lee Silverman, Julie Losman Aurore, William G. Kaelin, Jr., MD, Stefan Gross, Lenny Dang, Frank Salituro, Jeffrey Saunders, Marion Dorsch, Samuel Agresta, MD, David P. Schenkein, MD, Michael Su, Scott Biller
Journal: Blood
Blood (2012) 120 (21): 3509.
https://doi.org/10.1182/blood.V120.21.3509.3509
Published: 2012
Journal Articles

2-Hydroxyglutarate in IDH mutant AML: Predicting Patient Responses, Minimal Residual Disease and Correlations with Methylcytosine and Hydroxymethylcytosine Levels

Daniel A Pollyea, MD, MS, Holbrook E Kohrt, MD, Bing Zhang, MD, MS, James L. Zehnder, MD, David P. Schenkein, MD, Valeria Fantin, PhD, Kimberly Straley, BS, Aparna Vasanthakumar, BSc, MSc, PhD, Omar Abdel-Wahab, MD, Ross L Levine, MD, Lucy Godley, MD, PhD, Bruno C. Medeiros, MD
Journal: Blood
Blood (2011) 118 (21): 2509.
https://doi.org/10.1182/blood.V118.21.2509.2509
Published: 2011