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Journal Articles

An Intravital Imaging Protocol to Visualize and Phenotype the Hematopoietic Niche of Clonal Hematopoiesis

Kevin Lee, Melissa MacLiesh, Cih-Li Hong, Wimeth Dissanayake, Yuko Kawano, Hiroki Kawano, Christina Kaszuba, Benjamin Rodems, Judith M. Runnels, Michael W. Becker, Jeevisha Bajaj, Charles Lin, Laura Calvi, Shu-Chi Yeh

Blood (2023) 142 (Supplement 1): 5023.

https://doi.org/10.1182/blood-2023-190674

Published: 2023

Journal Articles

Citron Rho Interacting Kinase (CRIK) Regulates Survival in IL-6 Dependent Multiple Myeloma Cells.

Hai T. Ngo, Alexey A. Leontovich, PhD, Aldo M. Roccaro, MD, PhD, Abdel Kareem Azab, Bpharm, PhD, Judith M. Runnels, PhD, Feda Azab, BPharm, Antonio Sacco, Phong Quang, Kenneth C. Anderson, MD, Irene M. Ghobrial, M.D.

Blood (2009) 114 (22): 1825.

https://doi.org/10.1182/blood.V114.22.1825.1825

Published: 2009

Journal Articles

The Effect of the CXCR4 Inhibitors, AMD3100 and AMD3465, in Multiple Myeloma Cell Homing and Its Interaction with the Bone Marrow Microenvironment.

Judith M. Runnels, PhD, Abdel Kareem Azab, Bpharm, PhD, Costas Pitsillides, PhD, Jonathan Farag, Juwell Wu, Aldo M. Roccaro, MD, PhD, Patricia Maiso, PhD, Charles P. Lin, PhD, Irene M. Ghobrial, M.D.

Blood (2009) 114 (22): 1826.

https://doi.org/10.1182/blood.V114.22.1826.1826

Published: 2009

Journal Articles

MicroRNA Changes Occur in Multiple Myeloma Cells in the Context of Bone Marrow Milieu.

Roccaro M. Roccaro, MD, PhD, Antonio Sacco, Abdel Kareem Azab, BPharm, PhD, Feda Azab, BPharm, Hai Ngo, Molly R Melhem, Phong Quong, Judith M. Runnels, PhD, Kenneth C. Anderson, MD, Irene Ghobrial, M.D.

Blood (2009) 114 (22): 1785.

https://doi.org/10.1182/blood.V114.22.1785.1785

Published: 2009

Journal Articles

RAD001 Exerts Anti-Tumor Activity in Waldenstrom Macroglobulinemia.

Steven Vesole, Xiaoying Jia, Aldo M. Roccaro, MD, PhD, Antonio Sacco, Hai T. Ngo, Feda Azab, BPharm, Abdel Kareem Azab, BPharm, PhD, Molly R Melhem, Judith M. Runnels, PhD, Phong Quang, Kenneth C. Anderson, MD, Irene M. Ghobrial, M.D.

Blood (2009) 114 (22): 3732.

https://doi.org/10.1182/blood.V114.22.3732.3732

Published: 2009

Journal Articles

The Role of FGFR in the Progression of Waldenstrom's Macroglubulinemia and the Effect of Its Inhibition by TKI-258.

Feda Azab, BPharm, Abdel Kareem Azab, Bpharm, PhD, Aldo M. Roccaro, MD, PhD, Antonio Sacco, Phong Quang, Hai T Ngo, Molly R Melhem, Judith M. Runnels, PhD, Patricia Maiso, PhD, Irene M Ghobrial, M.D.

Blood (2009) 114 (22): 3737.

https://doi.org/10.1182/blood.V114.22.3737.3737

Published: 2009

Journal Articles

Selective Inhibition of the Chymotrypsin-Like Activity of the Immunoproteasome and Constitutive Proteasome Represents a Valid Anti-Tumor Strategy in Waldenstrom Macroglobulinemia.

Aldo M. Roccaro, MD, PhD, Antonio Sacco, Monette Aujay, Hai Ngo, Feda Azab, BPharm, Abdel Kareem Azab, PhD, BPharm, Molly Melhem, Judith M. Runnels, PhD, Phong Quang, Susan Demo, PhD, Irene Ghobrial, M.D.

Blood (2009) 114 (22): 4911.

https://doi.org/10.1182/blood.V114.22.4911.4911

Published: 2009

Journal Articles

Carfilzomib Exerts Anti-Neoplastic Activity in Waldenstrom Macroglobulinemia.

Antonio Sacco, Aldo M. Roccaro, MD, PhD, Monette Aujay, PhD, Hai Ngo, Feda Azab, BPharm, Abdel Kareem Azab, Bpharm, PhD, Molly R Melhem, Judith M. Runnels, PhD, Phong Quang, Susan Demo, PhD, Irene Ghobrial, M.D.

Blood (2009) 114 (22): 4916.

https://doi.org/10.1182/blood.V114.22.4916.4916

Published: 2009

Journal Articles

Role of Hypoxia in the Progression and Dissemination of Multiple Myeloma.

Abdel Kareem Azab, Bpharm, PhD, Phong Quang, Feda Azab, BPharm, Aldo M. Roccaro, MD, PhD, Antonio Sacco, Judith M. Runnels, PhD, Hai T. Ngo, Molly R Melhem, Patricia Maiso, PhD, Kenneth C. Anderson, MD, Charles P. Lin, PhD, Irene M. Ghobrial, M.D.

Blood (2009) 114 (22): 421.

https://doi.org/10.1182/blood.V114.22.421.421

Published: 2009

Journal Articles

Primary Waldesntrom Macroglobulinemia Cells Harbor Constitutive Activation of Akt, mTOR, Rictor and Raptor: Rational for Testing a Dual Inhibitor of the PI3K/Akt and mTOR Pathways in This Disease.

Aldo M. Roccaro, MD, PhD, Antonio Sacco, Emanuel N. Husu, Costas M Pitsillides, PhD, Steven Vesole, Abdel Kareem Azab, BPharm, PhD, Feda Azab, BPharm, Molly Melhem, Hai Ngo, Phong Quang, Patricia Maiso, PhD, Judith M. Runnels, PhD, Charles P. Lin, PhD, Kenneth C. Anderson, MD, Irene Ghobrial, M.D.

Blood (2009) 114 (22): 3843.

https://doi.org/10.1182/blood.V114.22.3843.3843

Published: 2009

Journal Articles

Role of Selectins in the Pathogenesis of Multiple Myeloma.

Abdel Kareem Azab, Bpharm, PhD, Phong Quang, Feda Azab, BPharm, Costas M Pitsillides, John T Patton, Theodore Smith, Arun Sarkar, Judith M. Runnels, PhD, Aldo M. Roccaro, MD, PhD, Antonio Sacco, Hai T. Ngo, Molly R Melhem, Patricia Maiso, PhD, Kenneth C. Anderson, MD, Charles P. Lin, PhD, John L. Magnani, Irene M. Ghobrial, M.D.

Blood (2009) 114 (22): 951.

https://doi.org/10.1182/blood.V114.22.951.951

Published: 2009

Journal Articles

Eph-B2 Receptor Tyrosine Kinase Is Overexpressed in Waldenstrom's Macroglubulinemia and Plays a Major Role in Its Interaction with the Bone Marrow Microenvironment.

Abdel Kareem Azab, Bpharm, PhD, Feda Azab, BPharm, Aldo M. Roccaro, MD, PhD, Antonio Sacco, Phong Quang, Hai T. Ngo, Molly R Melhem, Judith M. Runnels, PhD, Patricia Maiso, PhD, Irene M. Ghobrial, M.D.

Blood (2009) 114 (22): 2935.

https://doi.org/10.1182/blood.V114.22.2935.2935

Published: 2009

Journal Articles

RhoA and Rac1 GTPases play major and differential roles in stromal cell–derived factor-1–induced cell adhesion and chemotaxis in multiple myeloma

Abdel Kareem Azab, Feda Azab, Simona Blotta, Costas M. Pitsillides, Brian Thompson, Judith M. Runnels, Aldo M. Roccaro, Hai T. Ngo, Molly R. Melhem, Antonio Sacco, Xiaoying Jia, Kenneth C. Anderson, Charles P. Lin, Barrett J. Rollins, Irene M. Ghobrial

Blood (2009) 114 (3): 619–629.

https://doi.org/10.1182/blood-2009-01-199281

Published: 2009

Includes: Multimedia, Supplemental data

Journal Articles

CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy

Blood (2009) 113 (18): 4341–4351.

https://doi.org/10.1182/blood-2008-10-186668

Published: 2009

Includes: Supplemental data

Journal Articles

In Vivo Mobilization of Multiple Myeloma Cells Out of the Bone Marrow Using the CXCR4 Inhibitor AMD3100 and Bortezomib: Implications for Sensitization of Myeloma Cells to Apoptosis.

Judith M. Runnels, Abdelkareem Azab, Costas Pitsillides, Anne-Sophie Moreau, Feda Azab, Joel A. Spencer, Xavier Leleu, Alicia L. Carlson, Beatriz E. Ospina, Renee Wright, Xiaoying Jia, Hai Ngo, Andrew L. Kung, Charles P. Lin, Irene M. Ghobrial

Blood (2007) 110 (11): 2501.

https://doi.org/10.1182/blood.V110.11.2501.2501

Published: 2007

Journal Articles

A Novel Real-Time In Vivo Homing Model of Multiple Myeloma.

Judith M. Runnels, PhD, Costas Pitsillides, PhD, Joel A. Spencer, Joji Fujisaki, PhD, Hai Ngo, Evdoxia Hatjiharissi, MD, Xavier Leleu, MD, Anne-Sophie Moreau, MD, Xiaoying Jia, Teru Hideshima, MD, Nikhil Munshi, MD, Kenneth C. Anderson, PhD, Charles P. Lin, PhD, Irene M. Ghobrial, MD

Blood (2006) 108 (11): 242.

https://doi.org/10.1182/blood.V108.11.242.242

Published: 2006

NARROW

An Intravital Imaging Protocol to Visualize and Phenotype the Hematopoietic Niche of Clonal Hematopoiesis

Citron Rho Interacting Kinase (CRIK) Regulates Survival in IL-6 Dependent Multiple Myeloma Cells.

The Effect of the CXCR4 Inhibitors, AMD3100 and AMD3465, in Multiple Myeloma Cell Homing and Its Interaction with the Bone Marrow Microenvironment.

MicroRNA Changes Occur in Multiple Myeloma Cells in the Context of Bone Marrow Milieu.

RAD001 Exerts Anti-Tumor Activity in Waldenstrom Macroglobulinemia.

The Role of FGFR in the Progression of Waldenstrom's Macroglubulinemia and the Effect of Its Inhibition by TKI-258.

Selective Inhibition of the Chymotrypsin-Like Activity of the Immunoproteasome and Constitutive Proteasome Represents a Valid Anti-Tumor Strategy in Waldenstrom Macroglobulinemia.

Carfilzomib Exerts Anti-Neoplastic Activity in Waldenstrom Macroglobulinemia.

Role of Hypoxia in the Progression and Dissemination of Multiple Myeloma.

Primary Waldesntrom Macroglobulinemia Cells Harbor Constitutive Activation of Akt, mTOR, Rictor and Raptor: Rational for Testing a Dual Inhibitor of the PI3K/Akt and mTOR Pathways in This Disease.

Role of Selectins in the Pathogenesis of Multiple Myeloma.

Eph-B2 Receptor Tyrosine Kinase Is Overexpressed in Waldenstrom's Macroglubulinemia and Plays a Major Role in Its Interaction with the Bone Marrow Microenvironment.

RhoA and Rac1 GTPases play major and differential roles in stromal cell–derived factor-1–induced cell adhesion and chemotaxis in multiple myeloma

CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy

In Vivo Mobilization of Multiple Myeloma Cells Out of the Bone Marrow Using the CXCR4 Inhibitor AMD3100 and Bortezomib: Implications for Sensitization of Myeloma Cells to Apoptosis.

A Novel Real-Time In Vivo Homing Model of Multiple Myeloma.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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