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Journal Articles

MicroRNA Changes Occur in Multiple Myeloma Cells in the Context of Bone Marrow Milieu.

Roccaro M. Roccaro, MD, PhD, Antonio Sacco, Abdel Kareem Azab, BPharm, PhD, Feda Azab, BPharm, Hai Ngo, Molly R Melhem, Phong Quong, Judith M. Runnels, PhD, Kenneth C. Anderson, MD, Irene Ghobrial, M.D.

Blood (2009) 114 (22): 1785.

https://doi.org/10.1182/blood.V114.22.1785.1785

Published: 2009

Journal Articles

Eph-B2 Receptor Tyrosine Kinase Is Overexpressed in Waldenstrom's Macroglubulinemia and Plays a Major Role in Its Interaction with the Bone Marrow Microenvironment.

Abdel Kareem Azab, Bpharm, PhD, Feda Azab, BPharm, Aldo M. Roccaro, MD, PhD, Antonio Sacco, Phong Quang, Hai T. Ngo, Molly R Melhem, Judith M. Runnels, PhD, Patricia Maiso, PhD, Irene M. Ghobrial, M.D.

Blood (2009) 114 (22): 2935.

https://doi.org/10.1182/blood.V114.22.2935.2935

Published: 2009

Journal Articles

RAD001 Exerts Anti-Tumor Activity in Waldenstrom Macroglobulinemia.

Steven Vesole, Xiaoying Jia, Aldo M. Roccaro, MD, PhD, Antonio Sacco, Hai T. Ngo, Feda Azab, BPharm, Abdel Kareem Azab, BPharm, PhD, Molly R Melhem, Judith M. Runnels, PhD, Phong Quang, Kenneth C. Anderson, MD, Irene M. Ghobrial, M.D.

Blood (2009) 114 (22): 3732.

https://doi.org/10.1182/blood.V114.22.3732.3732

Published: 2009

Journal Articles

The Role of FGFR in the Progression of Waldenstrom's Macroglubulinemia and the Effect of Its Inhibition by TKI-258.

Feda Azab, BPharm, Abdel Kareem Azab, Bpharm, PhD, Aldo M. Roccaro, MD, PhD, Antonio Sacco, Phong Quang, Hai T Ngo, Molly R Melhem, Judith M. Runnels, PhD, Patricia Maiso, PhD, Irene M Ghobrial, M.D.

Blood (2009) 114 (22): 3737.

https://doi.org/10.1182/blood.V114.22.3737.3737

Published: 2009

Journal Articles

Role of Hypoxia in the Progression and Dissemination of Multiple Myeloma.

Abdel Kareem Azab, Bpharm, PhD, Phong Quang, Feda Azab, BPharm, Aldo M. Roccaro, MD, PhD, Antonio Sacco, Judith M. Runnels, PhD, Hai T. Ngo, Molly R Melhem, Patricia Maiso, PhD, Kenneth C. Anderson, MD, Charles P. Lin, PhD, Irene M. Ghobrial, M.D.

Blood (2009) 114 (22): 421.

https://doi.org/10.1182/blood.V114.22.421.421

Published: 2009

Journal Articles

Role of Selectins in the Pathogenesis of Multiple Myeloma.

Abdel Kareem Azab, Bpharm, PhD, Phong Quang, Feda Azab, BPharm, Costas M Pitsillides, John T Patton, Theodore Smith, Arun Sarkar, Judith M. Runnels, PhD, Aldo M. Roccaro, MD, PhD, Antonio Sacco, Hai T. Ngo, Molly R Melhem, Patricia Maiso, PhD, Kenneth C. Anderson, MD, Charles P. Lin, PhD, John L. Magnani, Irene M. Ghobrial, M.D.

Blood (2009) 114 (22): 951.

https://doi.org/10.1182/blood.V114.22.951.951

Published: 2009

Journal Articles

Carfilzomib Exerts Anti-Neoplastic Activity in Waldenstrom Macroglobulinemia.

Antonio Sacco, Aldo M. Roccaro, MD, PhD, Monette Aujay, PhD, Hai Ngo, Feda Azab, BPharm, Abdel Kareem Azab, Bpharm, PhD, Molly R Melhem, Judith M. Runnels, PhD, Phong Quang, Susan Demo, PhD, Irene Ghobrial, M.D.

Blood (2009) 114 (22): 4916.

https://doi.org/10.1182/blood.V114.22.4916.4916

Published: 2009

Journal Articles

RhoA and Rac1 GTPases play major and differential roles in stromal cell–derived factor-1–induced cell adhesion and chemotaxis in multiple myeloma

Abdel Kareem Azab, Feda Azab, Simona Blotta, Costas M. Pitsillides, Brian Thompson, Judith M. Runnels, Aldo M. Roccaro, Hai T. Ngo, Molly R. Melhem, Antonio Sacco, Xiaoying Jia, Kenneth C. Anderson, Charles P. Lin, Barrett J. Rollins, Irene M. Ghobrial

Blood (2009) 114 (3): 619–629.

https://doi.org/10.1182/blood-2009-01-199281

Published: 2009

Includes: Multimedia, Supplemental data

Journal Articles

MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma

Aldo M. Roccaro, Antonio Sacco, Brian Thompson, Xavier Leleu, Abdel Kareem Azab, Feda Azab, Judith Runnels, Xiaoying Jia, Hai T. Ngo, Molly R. Melhem, Charles P. Lin, Domenico Ribatti, Barrett J. Rollins, Thomas E. Witzig, Kenneth C. Anderson, Irene M. Ghobrial

Blood (2009) 113 (26): 6669–6680.

https://doi.org/10.1182/blood-2009-01-198408

Published: 2009

Includes: Supplemental data

Journal Articles

CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy

Blood (2009) 113 (18): 4341–4351.

https://doi.org/10.1182/blood-2008-10-186668

Published: 2009

Includes: Supplemental data

Journal Articles

microRNA expression in the biology, prognosis, and therapy of Waldenström macroglobulinemia

Aldo M. Roccaro, Antonio Sacco, Changzhong Chen, Judith Runnels, Xavier Leleu, Feda Azab, Abdel Kareem Azab, Xiaoying Jia, Hai T. Ngo, Molly R. Melhem, Nicholas Burwick, Lyuba Varticovski, Carl D. Novina, Barrett J. Rollins, Kenneth C. Anderson, Irene M. Ghobrial

Blood (2009) 113 (18): 4391–4402.

https://doi.org/10.1182/blood-2008-09-178228

Published: 2009

Includes: Supplemental data

Journal Articles

CXCR7 Regulates SDF-1 Induced Adhesion and Homing in Multiple Myeloma.

Nicholas Burwick, MD, Anne-Sophie Moreau, MD, Xiaoying Jia, Xavier Leleu, MD, PhD, Judith Runnels, Hai T. Ngo, Molly R. Melhem, Aldo M. Roccaro, MD, PhD, Abdel kareem Azab, PhD, Irene M. Ghobrial, M.D.

Blood (2008) 112 (11): 1674.

https://doi.org/10.1182/blood.V112.11.1674.1674

Published: 2008

Journal Articles

PKC412, a Small Molecule Tyrosine Kinase Inhibitor, Regulates Survival and Proliferation Pathways in Waldenström Macroglobulinemia

Molly R. Melhem, Aldo M. Roccaro, Abdelkareem Azab, Hai T. Ngo, Antonio Sacco, Xiaoying Jia, Feda Azab, Judith Runnels, Nicolas Burwick, Phong Quang, Emanuel N. Husu, Xavier Leleu, Kenneth C. Anderson, Irene M. Ghobrial

Blood (2008) 112 (11): 2614.

https://doi.org/10.1182/blood.V112.11.2614.2614

Published: 2008

Journal Articles

The Tyrosine Kinase Src Regulates Adhesion and Survival in Waldenström Macroglobulinemia

Hai T. Ngo, Mena Farag, Xiaoying Jia, Nicolas Burwick, MD, Molly R. Melhem, Xavier Leleu, MD, PhD, Judith Runnels, PhD, Abdel Kareem Azab, PhD, Aldo M. Roccaro, MD, PhD, Feda Azab, Antonio Sacco, Phong Quang, Yu-Tzu Tai, PhD, Kenneth C. Anderson, MD, Irene M. Ghobrial, MD

Blood (2008) 112 (11): 2615.

https://doi.org/10.1182/blood.V112.11.2615.2615

Published: 2008

Journal Articles

Dual PI3K and mTOR Inhibition in Waldenstrom Macroglobulinemia

Emanuel N. Husu, Aldo M. Roccaro, MD, PhD, Antonio Sacco, Molly R. Melhem, Abdel kareem Azab, PhD, Xiaoying Jia, Hai T. Ngo, Feda Azab, Judith Runnels, PhD, Phong Quang, Xavier Leleu, MD, PhD, Kenneth C. Anderson, MD, Irene M. Ghobrial, MD

Blood (2008) 112 (11): 4986.

https://doi.org/10.1182/blood.V112.11.4986.4986

Published: 2008

Journal Articles

The Effect of Insulin-Like Growth Factor 1 on Waldenstrom Macroglobulinemia

Molly R. Melhem, Aldo M. Roccaro, MD, PhD, Mena Farag, Abdel kareem Azab, PhD, Hai T. Ngo, Antonio Sacco, Xiaoying Jia, Feda Azab, Judith Runnels, PhD, Nicolas Burwick, MD, Phong Quang, Emanuel N. Husu, Hideshima Teru, MD, PhD, Kenneth C. Anderson, MD, Xavier Leleu, MD, PhD, Irene M. Ghobrial, M.D.

Blood (2008) 112 (11): 4994.

https://doi.org/10.1182/blood.V112.11.4994.4994

Published: 2008

Journal Articles

Regulation of Histone Deacetylase in Waldenström Macroglobulinemia

Xiaoying Jia, Aldo M. Roccaro, MD, PhD, Abdel Kareem Azab, PhD, Hai T. Ngo, Antonio Sacco, Molly R. Melhem, Feda Azab, Judith Runnels, PhD, Nicolas Burwick, MD, Phong Quang, Emanuel N. Husu, Xavier Leleu, MD, PhD, Kenneth C. Anderson, MD, James Bradner, MD, PhD, Irene M. Ghobrial, MD

Blood (2008) 112 (11): 2617.

https://doi.org/10.1182/blood.V112.11.2617.2617

Published: 2008

Journal Articles

Proteomic Analysis of Multiple Myeloma Identifies Upregulation of CRIK Protein, a Novel Protein Regulating Migration and Adhesion

Hai T. Ngo, Evdoxia Hatjiharissi, MD, Alexey A. Leontovich, PhD, Wee Chng, PhD, Mena Farag, Xavier Leleu, MD, PhD, Xiaoying Jia, Judith Runnels, PhD, Aldo Roccaro, MD, PhD, Abdel Kareem Azab, PhD, Feda Azab, Antonio Sacco, Nicholas Burwick, MD, Molly R. Melhem, Kenneth C. Anderson, MD, Rafael Fonseca, MD, Thomas E. Witzig, MD, Irene M. Ghobrial, MD

Blood (2008) 112 (11): 643.

https://doi.org/10.1182/blood.V112.11.643.643

Published: 2008

Journal Articles

Rho-a and Rac-1 GTPases Play Major and Differential Roles in SDF1α- Induced Cell Adhesion and Chemotaxis in Multiple Myeloma.

Abdel kareem Azab, Feda Azab, Costas M Pitsillides, Hai T. Ngo, Xiaoying Jia, Molly R. Melhem, Judith Runnels, Aldo M. Roccaro, MD, PhD, Antonio Sacco, Nicholas Burwick, Charles P Lin, Kenneth C Anderson, MD, Irene M. Ghobrial

Blood (2008) 112 (11): 1666.

https://doi.org/10.1182/blood.V112.11.1666.1666

Published: 2008

Journal Articles

MicroRNA Signature in Waldenstrom Macroglobulinemia

Aldo M Roccaro, Antonio Sacco, Changzhong Chen, Xavier Leleu, Judith Runnels, Feda Azab, Abdel Kareem Azab, Xiaoying Jia, Hai T Ngo, Molly R. Melhem, Nicholas Burwick, Phong Quang, Lyuba Varticovski, Carl D Novina, Barrett J. Rollins, Kenneth C. Anderson, Irene M. Ghobrial

Blood (2008) 112 (11): 630.

https://doi.org/10.1182/blood.V112.11.630.630

Published: 2008

NARROW

MicroRNA Changes Occur in Multiple Myeloma Cells in the Context of Bone Marrow Milieu.

Eph-B2 Receptor Tyrosine Kinase Is Overexpressed in Waldenstrom's Macroglubulinemia and Plays a Major Role in Its Interaction with the Bone Marrow Microenvironment.

RAD001 Exerts Anti-Tumor Activity in Waldenstrom Macroglobulinemia.

The Role of FGFR in the Progression of Waldenstrom's Macroglubulinemia and the Effect of Its Inhibition by TKI-258.

Role of Hypoxia in the Progression and Dissemination of Multiple Myeloma.

Role of Selectins in the Pathogenesis of Multiple Myeloma.

Carfilzomib Exerts Anti-Neoplastic Activity in Waldenstrom Macroglobulinemia.

RhoA and Rac1 GTPases play major and differential roles in stromal cell–derived factor-1–induced cell adhesion and chemotaxis in multiple myeloma

MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma

CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy

microRNA expression in the biology, prognosis, and therapy of Waldenström macroglobulinemia

CXCR7 Regulates SDF-1 Induced Adhesion and Homing in Multiple Myeloma.

PKC412, a Small Molecule Tyrosine Kinase Inhibitor, Regulates Survival and Proliferation Pathways in Waldenström Macroglobulinemia

The Tyrosine Kinase Src Regulates Adhesion and Survival in Waldenström Macroglobulinemia

Dual PI3K and mTOR Inhibition in Waldenstrom Macroglobulinemia

The Effect of Insulin-Like Growth Factor 1 on Waldenstrom Macroglobulinemia

Regulation of Histone Deacetylase in Waldenström Macroglobulinemia

Proteomic Analysis of Multiple Myeloma Identifies Upregulation of CRIK Protein, a Novel Protein Regulating Migration and Adhesion

Rho-a and Rac-1 GTPases Play Major and Differential Roles in SDF1α- Induced Cell Adhesion and Chemotaxis in Multiple Myeloma.

MicroRNA Signature in Waldenstrom Macroglobulinemia

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American Society of Hematology

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