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Joe R. Harman
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Journal Articles

Enhancer heterogeneity in acute lymphoblastic leukemia drives differential gene expression in patients

Open Access
Alastair L. Smith, Nicholas Denny, Catherine Chahrour, Kim Sharp, Marta Arachi, Ana M. Dopico-Fernandez, Natalina Elliott, Joe R. Harman, Thomas Jackson, Huimin Geng, Owen Smith, Jonathan Bond, Irene Roberts, Ronald W. Stam, Nicholas T. Crump, James O. J. Davies, Anindita Roy, Thomas A. Milne
Journal: Blood
Blood (2025) 146 (17): 2073–2087.
https://doi.org/10.1182/blood.2024028019
Published: 2025
Includes: Supplemental data
Journal Articles

The Fetal Specific Gene LIN28B Is Essential for Human Fetal B-Lymphopoiesis and Initiation of KMT2A-AFF1+ Infant Acute Lymphoblastic Leukemia

Free
Rebecca E Ling, Thomas Jackson, Natalina Elliott, Joe W Cross, Lucy Hamer, Arundhati S Wuppalapati, Alastair L Smith, Catherine M Chahrour, Okan Sevim, Deena Iskander, Guanlin Wang, Sorcha I O'Byrne, Siobhan Rice, Joe R Harman, Bethan Psaila, Rhys G Morgan, Irene Roberts, Thomas A Milne, Anindita Roy
Journal: Blood
Blood (2024) 144 (Supplement 1): 199.
https://doi.org/10.1182/blood-2024-198819
Published: 2024
Journal Articles

PPARG and ASS1: Targets of Metabolic Alteration in Venetoclax / Decitabine Resistant Acute Myeloid Leukemia

Free
Kotoko Yamatani, Tatsuro Watanabe, Kaori Saito, Abhishek Maiti, Satoshi Yamashita, Abdullah Khasawneh, Faith Jessica Paran, Kala Hayes, Gautam Borthakur, Joe R Harman, Shinya Kimura, Courtney D. DiNardo, Thomas A Milne, Michael Andreeff, Yoko Tabe, Marina Y. Konopleva
Journal: Blood
Blood (2023) 142 (Supplement 1): 4162.
https://doi.org/10.1182/blood-2023-178554
Published: 2023
Journal Articles

Sustained MYB Activity Is Necessary for Oncogenic Transcription in KMT2A -Rearranged Acute Lymphoblastic Leukemia through Enhancer-Promoter Interactions and Epigenetic Modifications at Enhancers

Free
I-Jun Lau, Joe R Harman, Nicole E Jackson, Nicholas Denny, Alastair L Smith, Paresh Vyas, James Oliver Davies, Jim Hughes, Nicholas Crump, Thomas Arthur Milne
Journal: Blood
Blood (2023) 142 (Supplement 1): 40.
https://doi.org/10.1182/blood-2023-185172
Published: 2023
Journal Articles

Molecular Profiling of Response and Resistance to Venetoclax-Decitabine Therapy in Acute Myeloid Leukemia

Free
Abdullah Khasawneh, Faith Jessica Paran, Rieko Oyama, Abhishek Maiti, Hussein A Abbas, Bofei Wang, Poonam N Desai, Kala Hayes, Joe R Harman, Xiaoping Su, Courtney D. DiNardo, Michael Andreeff, Thomas A Milne, Marina Y. Konopleva, Yoko Tabe
Journal: Blood
Blood (2023) 142 (Supplement 1): 4159.
https://doi.org/10.1182/blood-2023-180463
Published: 2023