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Journal Articles

Exploring Genetic and Non-Genetic Changes Driving Tumor Evolution in CK-AML at Single-Cell Resolution

Aino-Maija Leppä, Karen Grimes, Hyobin Jeong, Tobias Boch, Darja Karpova, Florian Grünschläger, Anna Jauch, Anna Dolnik, Bernardo Rodriguez-Martin, Lars Bullinger, Alwin Krämer, Ashley D Sanders, Jan O Korbel, Andreas Trumpp
Journal: Blood
Blood (2022) 140 (Supplement 1): 9170–9172.
https://doi.org/10.1182/blood-2022-166007
Published: 2022
Journal Articles

TP53 and KRAS Variants at Initial Diagnosis Identify an Ultra-High Risk Group of Pediatric T-Lymphoblastic Leukemia (T-ALL)

Tamara Kempter, Joachim B. Kunz, Paulina Richter-Pechanska, Katarzyna Tomska, Tobias Rausch, Busra Erarslan-Uysal, Cornelia Eckert, Martin Zimmermann, Martin Stanulla, Martin Schrappe, Gunnar Cario, Gabriele Escherich, Renate Kirschner-Schwabe, Martina U. Muckenthaler, Jan O. Korbel, Andreas E. Kulozik
Journal: Blood
Blood (2021) 138 (Supplement 1): 1315.
https://doi.org/10.1182/blood-2021-148420
Published: 2021
Journal Articles

Longitudinal Multilevel Omic Analysis of Pediatric T-ALL Reveals Distinct Mechanisms for Disease Progression in Type 1 and in Type 2 Relapses

Paulina Richter-Pechanska, PhD, Joachim B. Kunz, MD, Tobias Rausch, Busra Erarslan-Uysal, Beat Bornhauser, PhD, Viktoras Frismantas, PhD, Maria Pamela Dobay, PhD, Caroline Von Knebel Doeberitz, Martin Zimmermann, PhD, Stephan Fuhrmann, Martin Stanulla, MD PhD, Martin Schrappe, MD PhD, Gunnar Cario, MD, Gabriele Escherich, Kseniya Bakharevich, Renate Kirschner-Schwabe, PhD, Cornelia Eckert, PhD, Stefan Pfister, Martina U. Muckenthaler, PhD, Jean-Pierre Bourquin, MD PhD, Jan O. Korbel, PhD, Andreas E. Kulozik, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2826.
https://doi.org/10.1182/blood-2018-99-117978
Published: 2018
Journal Articles

Pediatric T-ALLs Developing into a Type 2 Relapse Originate from Cells That Carry the Potential of Variable Maturation into Subclones with Distinct Chromatin Landscapes

Büşra Erarslan-Uysal, Joachim B. Kunz, MD, Tobias Rausch, Paulina Richter-Pechanska, PhD, Sebastian Waszak, Viktoras Frismantas, PhD, Beat Bornhauser, PhD, Martin Zimmermann, PhD, Martin Stanulla, MD PhD, Martin Schrappe, MD PhD, Gunnar Cario, MD, Gabriele Escherich, Kseniya Bakharevich, Renate Kirschner-Schwabe, PhD, Cornelia Eckert, PhD, Tsvetomir Loukanov, Matthias Gorenflo, Martina U. Muckenthaler, PhD, Jean-Pierre Bourquin, MD PhD, Jan O. Korbel, PhD, Andreas E. Kulozik, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1545.
https://doi.org/10.1182/blood-2018-99-118255
Published: 2018
Journal Articles

PDX Models Recapitulate Genetics and Epigenetics of Pediatric T-Cell Leukemia

Caroline Von Knebel Doeberitz, Paulina Richter-Pechanska, PhD, Viktoras Frismantas, MSc, Joachim B. Kunz, MD, Tobias Rausch, Beat Bornhauser, PhD, Martin Zimmermann, PhD, Obul Reddy Bandapalli, PhD, Elena Orlova, Julia Seeman, Busra Erarslan, Yassen Assenov, Martin Stanulla, MD PhD, Martin Schrappe, MD PhD, Gunnar Cario, MD, Gabriele Escherich, MD, Kseniya Bakharevich, Renate Kirschner-Schwabe, PhD, Cornelia Eckert, PhD, Jan O. Korbel, PhD, Martina Muckenthaler, Jean-Pierre Bourquin, MD PhD, Andreas E. Kulozik, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2723.
https://doi.org/10.1182/blood.V130.Suppl_1.2723.2723
Published: 2017
Journal Articles

Relapsing Pediatric T-Cell Acute Lymphoblastic Leukemia Downregulates T-Cell Properties and Upregulates Cell Adhesion

Paulina Richter-Pechanska, PhD, Joachim B. Kunz, MD, Tobias Rausch, Caroline Von Knebel Doeberitz, Viktoras Frismantas, MSc, Maria Pamela Dobay, PhD, Beat Bornhauser, PhD, Martin Zimmermann, PhD, Obul Reddy Bandapalli, PhD, Stephan Fuhrmann, MD, Elena Orlova, Sebastian Uhrig, Gnana Prakash Balasubramanian, Martin Stanulla, MD PhD, Martin Schrappe, MD PhD, Gunnar Cario, MD, Gabriele Escherich, MD, Kseniya Bakharevich, Renate Kirschner-Schwabe, PhD, Cornelia Eckert, PhD, Stefan Pfister, Jan O. Korbel, PhD, Martina Muckenthaler, Jean-Pierre Bourquin, MD PhD, Andreas E. Kulozik, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2726.
https://doi.org/10.1182/blood.V130.Suppl_1.2726.2726
Published: 2017
Journal Articles

The Combination of MRD and Copy Number Alterations (CNAs) Defines an Ultra-High Risk Group of Children with Primary T-Lymphoblastic Leukemia (T-ALL)

Joachim B. Kunz, MD, Julia Seemann, Martin Zimmermann, PhD, Paulina Richter-Pechanska, Obul Reddy Bandapalli, PhD, Elena Orlova, Gunnar Cario, Martin Stanulla, MD, Martin Schrappe, MD PhD, Marketa Zaliova, Jan Trka, MD PhD, Renate Panzer-Grümayer, MD, Georg Mann, MD, Martina U. Muckenthaler, PhD, Jan O. Korbel, PhD, Andreas E Kulozik, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2911.
https://doi.org/10.1182/blood.V128.22.2911.2911
Published: 2016
Journal Articles

Identification of an Ultra High-Risk and Targetable Molecular Signature in Relapsed Pediatric T-ALL

Paulina Richter-Pechanska, PhD, Joachim B. Kunz, MD, Jana Hof, Martin Zimmermann, PhD, Tobias Rausch, PhD, Obul Reddy Bandapalli, PhD, Elena Orlova, Greta Scapinello, Judit Sagi, Martin Stanulla, MD, Martin Schrappe, MD PhD, Renate Kirschner-Schwabe, PhD, Cornelia Eckert, PhD, Vladimir Benes, PhD, Jan O. Korbel, PhD, Martina U. Muckenthaler, PhD, Andreas E Kulozik, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1084.
https://doi.org/10.1182/blood.V128.22.1084.1084
Published: 2016
Journal Articles

Gene Panel Sequencing of Primary and Relapsed Pediatric T-ALL Shows That Relapse-Specific Mutations Are Diverse and Mostly Non-Recurrent

Paulina Pechanska, Joachim Kunz, MD, Tobias Rausch, Obul Reddy Bandapalli, PhD, Elena Orlova, Judit Sagi, Martin Stanulla, MD, Martin Schrappe, MD PhD, Renate Kirschner-Schwabe, PhD, Jana Hof, Cornelia Eckert, Rolf Köhler, Martina U. Muckenthaler, PhD, Jan o. Korbel, Andreas E Kulozik, MDPhD
Journal: Blood
Blood (2015) 126 (23): 1428.
https://doi.org/10.1182/blood.V126.23.1428.1428
Published: 2015