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Journal Articles

Synergistic Activation of p53 Family of Proteins by the Combination of Nutlin 3a and SAHA in Acute Myelogenous Leukemia.

Gautam Borthakur, MD, Seshagiri Duvvuri, Ismael J. Samudio, PhD, Kensuke Kojima, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD

Blood (2009) 114 (22): 1738.

https://doi.org/10.1182/blood.V114.22.1738.1738

Published: 2009

Journal Articles

Pharmacological Inhibition of Fatty Acid Oxidation as a Novel Therapeutic Concept for Acute Myeloid Leukemia.

Michael Andreeff, MD, PhD, Michael Fiegl, PhD, Marina Konopleva, MD, PhD, Borys Korchin, Kumar Kaluarachchi, PhD, William G. Bornmann, PhD, Patrick H. Guthrie, BS, Romain Harmancey, PhD, Heinrich Taegtmeyer, MD, PhD, Ismael J. Samudio, PhD

Blood (2009) 114 (22): 3779.

https://doi.org/10.1182/blood.V114.22.3779.3779

Published: 2009

Journal Articles

Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML

Zhihong Zeng, Yue Xi Shi, Ismael J. Samudio, Rui-Yu Wang, Xiaoyang Ling, Olga Frolova, Mark Levis, Joshua B. Rubin, Robert R. Negrin, Elihu H. Estey, Sergej Konoplev, Michael Andreeff, Marina Konopleva

Blood (2009) 113 (24): 6215–6224.

https://doi.org/10.1182/blood-2008-05-158311

Published: 2009

Includes: Supplemental data

Journal Articles

CXCR4 Expression and Biological Activity Is Dependent on Oxygen Partial Pressure in Acute Myeloid Leukemia.

Michael Fiegl, Ph.D., Ismael J. Samudio, Ph.D., Karen Clise Dwyer, Ph.D., Jared Burks, Ph.D., Herbert Fritsche, Ph.D., Zakar H. Mnjoyan, Ph.D., Michael Andreeff, M.D., Ph.D.

Blood (2008) 112 (11): 938.

https://doi.org/10.1182/blood.V112.11.938.938

Published: 2008

Journal Articles

Targeting Anaplerotic Pathways That Support Fatty Acid Metabolism as a Therapeutic Strategy for Hematological Malignancies: The Achilles’ Heel of the Warburg Effect.

Ismael J. Samudio, PhD, Michael Fiegl, PhD, Marina Konopleva, MD, PhD, Kumar Kaluarachchi, PhD, John S. McMurray, PhD, BS, Borys Korchin, Karen Clise Dwyer, PhD, Romain Harmancey, PhD, Patrick Guthrie, BS, Heinrich Taegtmeyer, MD, PhD, Michael Andreeff, MD, PhD

Blood (2008) 112 (11): 1631.

https://doi.org/10.1182/blood.V112.11.1631.1631

Published: 2008

Journal Articles

Targeting the Hypoxic Microenvironment by mTOR Inhibitors Sensitizes ALL Cells to Chemotherapy

Olga Frolova, MD, PhD, Ismael J. Samudio, PhD, Zakar H. Mnjoyan, PhD, Hongbo Lu, Sergej Konoplev, MD, PhD, Deborah A. Thomas, MD, Hagop M. Kantarjian, MD, Elizabeth J. Shpall, MD, Michael Andreeff, MD, PhD, Marina Konopleva, MD, PhD

Blood (2008) 112 (11): 18.

https://doi.org/10.1182/blood.V112.11.18.18

Published: 2008

Journal Articles

Apoptosis Inducing Factor Acts as a Survival Factor in Acute Myelogenous Leukemia through Mitochondrial Complex 1.

Rui-yu Wang, MD, PhD, Ismael J. Samudio, PhD, Teresa McQueen, BS, Wendy D. Schober, MLT, Vivian R. Ruvolo, Steven Kornblau, MD, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD

Blood (2007) 110 (11): 1812.

https://doi.org/10.1182/blood.V110.11.1812.1812

Published: 2007

Journal Articles

Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML

Zhihong Zeng, Dos D. Sarbassov, Ismael J. Samudio, Karen W. L. Yee, Mark F. Munsell, C. Ellen Jackson, Francis J. Giles, David M. Sabatini, Michael Andreeff, Marina Konopleva

Blood (2006) 109 (8): 3509–3512.

https://doi.org/10.1182/blood-2006-06-030833

Published: 2006

Includes: Supplemental data

Journal Articles

A Novel Peptide Containing a Nine Amino Acid Sequence from Nur77 Induces Bcl-2-Dependent Apoptosis in AML.

Michael Andreeff, MD, PhD, Marina Konopleva, M.D., Ph.D., Julie C. Watt, Ismael J. Samudio, Ph.D., Arnold C. Satterthwait, Ph.D., Shinichi Kitada, M.D., Ph.D., Xiao-kun Zhang, Ph.D., John C. Reed, M.D., Ph.D.

Blood (2006) 108 (11): 2607.

https://doi.org/10.1182/blood.V108.11.2607.2607

Published: 2006

Journal Articles

MDM2 Inhibitor Nutlin-3a Induces p53-Dependent Apoptosis Via Transcription-Dependent and -Independent Pathways and Overcomes Fludarabine-Resistance in CLL.

Kensuke Kojima, MD, PhD, Marina Konopleva, MD, PhD, Ismael J. Samudio, PhD, Teresa McQueen, BS, Twee Tsao, Zhihong Zeng, MD, William K. Plunkett, PhD, Michael Andreeff, MD, PhD

Blood (2005) 106 (11): 445.

https://doi.org/10.1182/blood.V106.11.445.445

Published: 2005

Journal Articles

MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy

Kensuke Kojima, Marina Konopleva, Ismael J. Samudio, Masato Shikami, Maria Cabreira-Hansen, Teresa McQueen, Vivian Ruvolo, Twee Tsao, Zhihong Zeng, Lyubomir T. Vassilev, Michael Andreeff

Blood (2005) 106 (9): 3150–3159.

https://doi.org/10.1182/blood-2005-02-0553

Published: 2005

Journal Articles

A Novel Ring-Substituted Diindolylmethane 1,1-bis [3′-(5-methoxyindolyl)]-1-(p-t-butylphenyl) Methane Abrogates ERK Activation and Induces Apoptosis in Acute Myeloid Leukemia (AML).

Rooha Contractor, Ismael J. Samudio, Ph.D., Zeev Estrov, M.D., David Harris, James A. McCubrey, Ph.D., Stephen H. Safe, Ph.D., Michael Andreeff, M.D., Ph.D., Marina Konopleva, M.D., Ph.D.

Blood (2004) 104 (11): 3399.

https://doi.org/10.1182/blood.V104.11.3399.3399

Published: 2004

NARROW

Synergistic Activation of p53 Family of Proteins by the Combination of Nutlin 3a and SAHA in Acute Myelogenous Leukemia.

Pharmacological Inhibition of Fatty Acid Oxidation as a Novel Therapeutic Concept for Acute Myeloid Leukemia.

Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML

CXCR4 Expression and Biological Activity Is Dependent on Oxygen Partial Pressure in Acute Myeloid Leukemia.

Targeting Anaplerotic Pathways That Support Fatty Acid Metabolism as a Therapeutic Strategy for Hematological Malignancies: The Achilles’ Heel of the Warburg Effect.

Targeting the Hypoxic Microenvironment by mTOR Inhibitors Sensitizes ALL Cells to Chemotherapy

Apoptosis Inducing Factor Acts as a Survival Factor in Acute Myelogenous Leukemia through Mitochondrial Complex 1.

Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML

A Novel Peptide Containing a Nine Amino Acid Sequence from Nur77 Induces Bcl-2-Dependent Apoptosis in AML.

MDM2 Inhibitor Nutlin-3a Induces p53-Dependent Apoptosis Via Transcription-Dependent and -Independent Pathways and Overcomes Fludarabine-Resistance in CLL.

MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy

A Novel Ring-Substituted Diindolylmethane 1,1-bis [3′-(5-methoxyindolyl)]-1-(p-t-butylphenyl) Methane Abrogates ERK Activation and Induces Apoptosis in Acute Myeloid Leukemia (AML).

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American Society of Hematology

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ASH Publications

American Society of Hematology

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