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Journal Articles

IL3R Directed Agents, SL-401 and SL-501, Inhibit the Growth of Leukemia Stem Cells In CML.

Olga Frolova, MD, PhD, Arthur E Frankel, MD, Borys Korchin, MD, PhD, Jorge Cortes, MD, Hagop M. Kantarjian, MD, Michael Andreeff, MD, Ph.D., Marina Konopleva, MD, PhD

Blood (2010) 116 (21): 3403.

https://doi.org/10.1182/blood.V116.21.3403.3403

Published: 2010

Journal Articles

Role of Hypoxia and Hypoxia-Inducible-Factor 1α (HIF1A) In the BM Microenvironment-Mediated Protection of Leukemic Cells.

Rodrigo Jacamo, Juliana Benito, Ph.D., Olga Frolova, MD, PhD, Ye Chen, Hongbo Lu, MMSC, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD

Blood (2010) 116 (21): 2586.

https://doi.org/10.1182/blood.V116.21.2586.2586

Published: 2010

Journal Articles

Therapeutic Targeting of the Hypoxic Microenvironment in Acute Lymphocytic Leukemia.

Marina Konopleva, MD, PhD, Juliana Benito, PhD, Yue-Xi Shi, Sergej Konoplev, MD, PhD, Steven M. Kornblau, MD, Olga Frolova, MD, PhD, Patrick A. Zweidler-McKay, MD, PhD, YiHua Qiu, MD, MS, William R. Wilson, PhD, Dario Campana, MD, PhD, Rodrigo Jacamo, PhD, Hongbo Lu, MMSC, Wendy Fang, MD, Gautam Borthakur, MD, Carlos E. Bueso-Ramos, MD, Hagop M. Kantarjian, MD, Deborah A. Thomas, MD, Michael Andreeff, MD, PhD

Blood (2009) 114 (22): 2040.

https://doi.org/10.1182/blood.V114.22.2040.2040

Published: 2009

Journal Articles

Targeting IL3 Receptor in Chronic Myeloid Leukemia.

Olga Frolova, MD, PhD, Rui-Yu Wang, MD, PhD, Borys Korchin, Julie C. Watt, Jorge Cortes, MD, Arthur E. Frankel, MD, Hagop M. Kantarjian, MD, Michael Andreeff, MD, PhD, Marina Konopleva, MD, PhD

Blood (2009) 114 (22): 2172.

https://doi.org/10.1182/blood.V114.22.2172.2172

Published: 2009

Journal Articles

Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML

Zhihong Zeng, Yue Xi Shi, Ismael J. Samudio, Rui-Yu Wang, Xiaoyang Ling, Olga Frolova, Mark Levis, Joshua B. Rubin, Robert R. Negrin, Elihu H. Estey, Sergej Konoplev, Michael Andreeff, Marina Konopleva

Blood (2009) 113 (24): 6215–6224.

https://doi.org/10.1182/blood-2008-05-158311

Published: 2009

Includes: Supplemental data

Journal Articles

Targeting the Hypoxic Microenvironment by mTOR Inhibitors Sensitizes ALL Cells to Chemotherapy

Olga Frolova, MD, PhD, Ismael J. Samudio, PhD, Zakar H. Mnjoyan, PhD, Hongbo Lu, Sergej Konoplev, MD, PhD, Deborah A. Thomas, MD, Hagop M. Kantarjian, MD, Elizabeth J. Shpall, MD, Michael Andreeff, MD, PhD, Marina Konopleva, MD, PhD

Blood (2008) 112 (11): 18.

https://doi.org/10.1182/blood.V112.11.18.18

Published: 2008

Journal Articles

Relationship between mTOR-Mediated Upregulation of Glycolysis and Chemosensitivity of ALL Blasts.

Olga Frolova, MD, PhD, Daniela Buglio, Ph.D., Ismael Samudio, Ph.D., Teresa McQueen, Hagop Kantarjian, M.D., Mary A. Weiser, M.D., Ph.D., Michael Andreeff, M.D., Ph.D., Marina Konopleva, M.D., Ph.D.

Blood (2006) 108 (11): 1833.

https://doi.org/10.1182/blood.V108.11.1833.1833

Published: 2006

Journal Articles

Immunomodulatory Effects of the Triterpenoid CDDO after Allogeneic Bone Marrow Transplantation in Mice: Reduction of Acute Graft-Versus-Host Disease Lethality.

William J. Murphy, PhD, Olga Frolova, MD, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD, Weihong Ma, MD, Danice Wilkins, Lisbeth A. Welniak, PhD, Kai Sun, MD, PhD

Blood (2005) 106 (11): 1316.

https://doi.org/10.1182/blood.V106.11.1316.1316

Published: 2005

Journal Articles

A Novel Mechanism of Action of Methyl-2-cyano-3,12 dioxoolean-1,9 diene-28-oate (CDDO-Me): Direct Permeabilization of the Inner Mitochondrial Membrane To Inhibit Electron Transport and Induce Apoptosis.

Ismael Samudio, PhD, Marina Konopleva, MD, PhD, Helene Pelicano, PhD, Peng Huang, MD, PhD, Olga Frolova, PhD, William Bornmann, PhD, Yun-ming Ying, Randall Evans, PhD, Michael Andreeff, MD, PhD

Blood (2005) 106 (11): 4462.

https://doi.org/10.1182/blood.V106.11.4462.4462

Published: 2005

NARROW

IL3R Directed Agents, SL-401 and SL-501, Inhibit the Growth of Leukemia Stem Cells In CML.

Role of Hypoxia and Hypoxia-Inducible-Factor 1α (HIF1A) In the BM Microenvironment-Mediated Protection of Leukemic Cells.

Therapeutic Targeting of the Hypoxic Microenvironment in Acute Lymphocytic Leukemia.

Targeting IL3 Receptor in Chronic Myeloid Leukemia.

Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML

Targeting the Hypoxic Microenvironment by mTOR Inhibitors Sensitizes ALL Cells to Chemotherapy

Relationship between mTOR-Mediated Upregulation of Glycolysis and Chemosensitivity of ALL Blasts.

Immunomodulatory Effects of the Triterpenoid CDDO after Allogeneic Bone Marrow Transplantation in Mice: Reduction of Acute Graft-Versus-Host Disease Lethality.

A Novel Mechanism of Action of Methyl-2-cyano-3,12 dioxoolean-1,9 diene-28-oate (CDDO-Me): Direct Permeabilization of the Inner Mitochondrial Membrane To Inhibit Electron Transport and Induce Apoptosis.

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American Society of Hematology

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American Society of Hematology

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