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Journal Articles

Ribavirin-Induced Intracellular GTP Depletion Upregulates Factor VII Expression

Atsuo Suzuki, Yuhri Miyawaki, Eriko Okuyama, Moe Murata, Ando Yumi, Io Kato, Yuki Takagi, Akira Takagi, PhD, Takashi Murate, MD, PhD, Hidehiko Saito, MD, PhD, Tetsuhito Kojima, MD, PhD

Blood (2012) 120 (21): 1113.

https://doi.org/10.1182/blood.V120.21.1113.1113

Published: 2012

Journal Articles

Heterozygous ITGA2B R995W mutation inducing constitutive activation of the αIIbβ3 receptor affects proplatelet formation and causes congenital macrothrombocytopenia

Shinji Kunishima, Hirokazu Kashiwagi, Makoto Otsu, Naoya Takayama, Koji Eto, Masafumi Onodera, Yuji Miyajima, Yasushi Takamatsu, Junji Suzumiya, Kousaku Matsubara, Yoshiaki Tomiyama, Hidehiko Saito

Blood (2011) 117 (20): 5479–5484.

https://doi.org/10.1182/blood-2010-12-323691

Published: 2011

Includes: Supplemental data

Journal Articles

R702C Mutation of the MYH9 Gene Provokes Impaired Platelet Formation, Renal Focal Segmental Glomerulosclerosis, and Hearing Disability In the Mice Model

Nobuaki Suzuki, Shinji Kunishima, PhD, Makoto Ikejiri, Shoichi Maruyama, MD, PhD, Michihiko Sone, MD, PhD, Akira Takagi, Kanji Hirashima, Masahito Ikawa, Masaru Okabe, Tetsuhito Kojima, MD, PhD, Hidehiko Saito, MD, Tomoki Naoe, MD, PhD, Tadashi Matsushita, MD, PhD

Blood (2010) 116 (21): 482.

https://doi.org/10.1182/blood.V116.21.482.482

Published: 2010

Journal Articles

Response:W318 β1-tubulin and macrothrombocytopenia

Shinji Kunishima, Hidehiko Saito

Blood (2009) 114 (2): 492–493.

https://doi.org/10.1182/blood-2009-05-218495

Published: 2009

Journal Articles

Mutation of the β1-tubulin gene associated with congenital macrothrombocytopenia affecting microtubule assembly

Shinji Kunishima, Ryoji Kobayashi, Tomohiko J. Itoh, Motohiro Hamaguchi, Hidehiko Saito

Blood (2009) 113 (2): 458–461.

https://doi.org/10.1182/blood-2008-06-162610

Published: 2009

Includes: Supplemental data

Journal Articles

Differential expression of wild-type and mutant NMMHC-IIA polypeptides in blood cells suggests cell-specific regulation mechanisms in MYH9 disorders

Shinji Kunishima, Motohiro Hamaguchi, Hidehiko Saito

Blood (2008) 111 (6): 3015–3023.

https://doi.org/10.1182/blood-2007-10-116194

Published: 2008

Journal Articles

Efficacy and Safety of Recombinant Human Soluble Thrombomodulin (ART-123) in Disseminated Intravascular Coagulation (DIC): Results of Phase III Randomized, Double-Blind, Clinical Trial.

Hidehiko Saito, MD, Ikuro Maruyama, MD, Shuji Shimazaki, MD, Yasuhiro Yamamoto, MD, Naoki Aikawa, MD, FACS, Ryuzo Ohno, MD, Akio Hirayama, MD, Tamotsu Matsuda, MD, Hidesaku Asakura, MD, Mitsuyoshi Nakashima, MD, Nobuo Aoki, MD

Blood (2006) 108 (11): 576.

https://doi.org/10.1182/blood.V108.11.576.576

Published: 2006

Journal Articles

The Stress-Induced PAI-1 Expression Is Enhanced in Obese Mice: A Possible Mechanism of Stress-Associated Thrombosis in Obese Subjects.

Koji Yamamoto, MD, PhD, Tetsuhito Kojima, MD, Tatsuya Adachi, MD, Mutsuharu Hayashi, MD, Tadashi Matsushita, MD, Junki Takamatsu, MD, David J. Loskutoff, PhD, Hidehiko Saito, MD

Blood (2004) 104 (11): 2984.

https://doi.org/10.1182/blood.V104.11.2984.2984

Published: 2004

Journal Articles

Different antiapoptotic pathways between wild-type and mutated FLT3: insights into therapeutic targets in leukemia

Yosuke Minami, Kazuhito Yamamoto, Hitoshi Kiyoi, Ryuzo Ueda, Hidehiko Saito, Tomoki Naoe

Blood (2003) 102 (8): 2969–2975.

https://doi.org/10.1182/blood-2002-12-3813

Published: 2003

Journal Articles

Aging and obesity augment the stress-induced expression of tissue factor gene in the mouse

Koji Yamamoto, Takayoshi Shimokawa, Hong Yi, Ken-ichi Isobe, Tetsuhito Kojima, David J. Loskutoff, Hidehiko Saito

Blood (2002) 100 (12): 4011–4018.

https://doi.org/10.1182/blood-2002-03-0945

Published: 2002

Journal Articles

Aberrant DNA methylation of p57 KIP2 gene in the promoter region in lymphoid malignancies of B-cell phenotype

Yinghua Li, Hirokazu Nagai, Toshihito Ohno, Masaaki Yuge, Sonoko Hatano, Etsuro Ito, Naoyoshi Mori, Hidehiko Saito, Tomohiro Kinoshita

Blood (2002) 100 (7): 2572–2577.

https://doi.org/10.1182/blood-2001-11-0026

Published: 2002

Journal Articles

Impact of antithrombin deficiency in thrombogenesis: lipopolysaccharide and stress-induced thrombus formation in heterozygous antithrombin-deficient mice

Masamitsu Yanada, Tetsuhito Kojima, Kazuhiro Ishiguro, Yukiko Nakayama, Koji Yamamoto, Tadashi Matsushita, Kenji Kadomatsu, Masahiko Nishimura, Takashi Muramatsu, Hidehiko Saito

Blood (2002) 99 (7): 2455–2458.

https://doi.org/10.1182/blood.V99.7.2455

Published: 2002

Journal Articles

Histone deacetylase 3 associates with and represses the transcription factor GATA-2

Yukiyasu Ozawa, Masayuki Towatari, Shinobu Tsuzuki, Fumihiko Hayakawa, Takahiro Maeda, Yasuhiko Miyata, Mitsune Tanimoto, Hidehiko Saito

Blood (2001) 98 (7): 2116–2123.

https://doi.org/10.1182/blood.V98.7.2116

Published: 2001

Journal Articles

Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies

Blood (2001) 97 (8): 2434–2439.

https://doi.org/10.1182/blood.V97.8.2434

Published: 2001

Journal Articles

Constitutive kinase activation of the TEL-Syk fusion gene in myelodysplastic syndrome with t(9;12)(q22;p12)

Yoshie Kuno, Akihiro Abe, Nobuhiko Emi, Minako Iida, Toshiya Yokozawa, Masayuki Towatari, Mitsune Tanimoto, Hidehiko Saito

Blood (2001) 97 (4): 1050–1055.

https://doi.org/10.1182/blood.V97.4.1050

Published: 2001

Journal Articles

Mutations in the NMMHC-A gene cause autosomal dominant macrothrombocytopenia with leukocyte inclusions (May-Hegglin anomaly/Sebastian syndrome)

Shinji Kunishima, Tetsuhito Kojima, Tadashi Matsushita, Toshihiro Tanaka, Masahito Tsurusawa, Yoshio Furukawa, Yukitsugu Nakamura, Takashi Okamura, Norihiko Amemiya, Takayuki Nakayama, Tadashi Kamiya, Hidehiko Saito

Blood (2001) 97 (4): 1147–1149.

https://doi.org/10.1182/blood.V97.4.1147

Published: 2001

Journal Articles

Up-regulation of costimulatory/adhesion molecules by histone deacetylase inhibitors in acute myeloid leukemia cells

Takahiro Maeda, Masayuki Towatari, Hiroshi Kosugi, Hidehiko Saito

Blood (2000) 96 (12): 3847–3856.

https://doi.org/10.1182/blood.V96.12.3847

Published: 2000

Journal Articles

Prognostic Implication of FLT3 and N- RAS Gene Mutations in Acute Myeloid Leukemia

Hitoshi Kiyoi, Tomoki Naoe, Yasuyuki Nakano, Shohei Yokota, Saburo Minami, Shuichi Miyawaki, Norio Asou, Kazutaka Kuriyama, Itsuro Jinnai, Chihiro Shimazaki, Hideki Akiyama, Kenji Saito, Hakumei Oh, Toshiko Motoji, Eijiro Omoto, Hidehiko Saito, Ryuzo Ohno, Ryuzo Ueda

Blood (1999) 93 (9): 3074–3080.

https://doi.org/10.1182/blood.V93.9.3074

Published: 1999

Journal Articles

ERGIC-53 Gene Structure and Mutation Analysis in 19 Combined Factors V and VIII Deficiency Families

Blood (1999) 93 (7): 2261–2266.

https://doi.org/10.1182/blood.V93.7.2261

Published: 1999

Journal Articles

Hypermethylation of p15 INK4B Gene in a Patient With Acute Myelogenous Leukemia Evolved From Paroxysmal Nocturnal Hemoglobinuria

Toshiki Uchida, Haruhiko Ohashi, Tomohiro Kinoshita, Hidehiko Saito, Ryo Taguchi, Tomomitsu Hotta, Takashi Murate

Blood (1998) 92 (8): 2981–2983.

https://doi.org/10.1182/blood.V92.8.2981

Published: 1998

NARROW

Ribavirin-Induced Intracellular GTP Depletion Upregulates Factor VII Expression

Heterozygous ITGA2B R995W mutation inducing constitutive activation of the αIIbβ3 receptor affects proplatelet formation and causes congenital macrothrombocytopenia

R702C Mutation of the MYH9 Gene Provokes Impaired Platelet Formation, Renal Focal Segmental Glomerulosclerosis, and Hearing Disability In the Mice Model

Response:W318 β1-tubulin and macrothrombocytopenia

Mutation of the β1-tubulin gene associated with congenital macrothrombocytopenia affecting microtubule assembly

Differential expression of wild-type and mutant NMMHC-IIA polypeptides in blood cells suggests cell-specific regulation mechanisms in MYH9 disorders

Efficacy and Safety of Recombinant Human Soluble Thrombomodulin (ART-123) in Disseminated Intravascular Coagulation (DIC): Results of Phase III Randomized, Double-Blind, Clinical Trial.

The Stress-Induced PAI-1 Expression Is Enhanced in Obese Mice: A Possible Mechanism of Stress-Associated Thrombosis in Obese Subjects.

Different antiapoptotic pathways between wild-type and mutated FLT3: insights into therapeutic targets in leukemia

Aging and obesity augment the stress-induced expression of tissue factor gene in the mouse

Aberrant DNA methylation of p57 KIP2 gene in the promoter region in lymphoid malignancies of B-cell phenotype

Impact of antithrombin deficiency in thrombogenesis: lipopolysaccharide and stress-induced thrombus formation in heterozygous antithrombin-deficient mice

Histone deacetylase 3 associates with and represses the transcription factor GATA-2

Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies

Constitutive kinase activation of the TEL-Syk fusion gene in myelodysplastic syndrome with t(9;12)(q22;p12)

Mutations in the NMMHC-A gene cause autosomal dominant macrothrombocytopenia with leukocyte inclusions (May-Hegglin anomaly/Sebastian syndrome)

Up-regulation of costimulatory/adhesion molecules by histone deacetylase inhibitors in acute myeloid leukemia cells

Prognostic Implication of FLT3 and N- RAS Gene Mutations in Acute Myeloid Leukemia

ERGIC-53 Gene Structure and Mutation Analysis in 19 Combined Factors V and VIII Deficiency Families

Hypermethylation of p15 INK4B Gene in a Patient With Acute Myelogenous Leukemia Evolved From Paroxysmal Nocturnal Hemoglobinuria

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American Society of Hematology

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ASH Publications

American Society of Hematology

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