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Journal Articles

Mutations in the SRP54 gene cause severe congenital neutropenia as well as Shwachman-Diamond–like syndrome

Christine Bellanné-Chantelot, Barbara Schmaltz-Panneau, Caroline Marty, Odile Fenneteau, Isabelle Callebaut, Séverine Clauin, Aurélie Docet, Gandhi-Laurent Damaj, Thierry Leblanc, Isabelle Pellier, Cécile Stoven, Sylvie Souquere, Iléana Antony-Debré, Blandine Beaupain, Nathalie Aladjidi, Vincent Barlogis, Frédéric Bauduer, Philippe Bensaid, Odile Boespflug-Tanguy, Claire Berger, Yves Bertrand, Liana Carausu, Claire Fieschi, Claire Galambrun, Aline Schmidt, Hubert Journel, Françoise Mazingue, Brigitte Nelken, Thuan Chong Quah, Eric Oksenhendler, Marie Ouachée, Marlène Pasquet, Véronique Saada, Felipe Suarez, Gérard Pierron, William Vainchenker, Isabelle Plo, Jean Donadieu
Journal: Blood
Blood (2018) 132 (12): 1318–1331.
https://doi.org/10.1182/blood-2017-12-820308
Published: 2018
Includes: Supplemental data
Journal Articles

Fertility Status Among Long-Term Childhood Acute Lymphoblastic Leukemia Survivors Enrolled between 1971 and 1998 in the EORTC Children Leukemia Group Trials 58741, 58831/2 and 58881

Teresa De Rojas, MD, Michal Kicinski, Stefan Suciu, Yves Benoit, Françoise Mazingue, Els Vandecruys, Geneviève Plat, Anne Uyttebroeck, Patric Lutz, Marie-Françoise Dresse, Pauline Simon, Claire Pluchart, Odile Minckes, Alina Ferster, MD, Claire Freycon, Frédéric Millot, Jutte Van Der Werff, Christophe Chantrain, Robert Paulus, Pierre Rohrlich, Caroline Piette
Journal: Blood
Blood (2017) 130 (Supplement 1): 2563.
https://doi.org/10.1182/blood.V130.Suppl_1.2563.2563
Published: 2017
Journal Articles

Socioeconomic Outcomes Among Long-Term Childhood Acute Lymphoblastic Leukemia Survivors Enrolled between 1971 and 1998 in the EORTC Children Leukemia Group Trials 58741, 58831/2 and 58881

Melissa Barbati, Michal Kicinski, Stefan Suciu, Yves Benoit, Françoise Mazingue, Teresa De Rojas, MD, Els Vandecruys, Geneviève Plat, Anne Uyttebroeck, Patric Lutz, Marie-Françoise Dresse, Pauline Simon, Claire Pluchart, Odile Minckes, Alina Ferster, MD, Claire Freycon, Frédéric Millot, Jutte Van Der Werff, Christophe Chantrain, Robert Paulus, Pierre Rohrlich, Caroline Piette
Journal: Blood
Blood (2017) 130 (Supplement 1): 2191.
https://doi.org/10.1182/blood.V130.Suppl_1.2191.2191
Published: 2017
Journal Articles

Mutations in SRP54 Gene Cause Severe Primary Neutropenia As Well As Shwachman-Diamond-like Syndrome

Christine Bellanné-Chantelot, PharmD, PhD, Caroline Marty, PhD, Barbara Schmaltz-Panneau, PhD, Odile Fenneteau, MD, Isabelle Callebaut, PhD, Séverine Clauin, Aurélie Docet, Gandhi Damaj, MD, Thierry Leblanc, MD, Isabelle Pellier, MD, Cécile Stoven, MD, Sylvie Souquere, PhD, Iléana Antony-Debre, PhD, Blandine Beaupain, MsC, Nathalie Aladjidi, MD, Vincent Barlogis, MD, Frederic Bauduer, MD PhD, Philippe Bensaid, MD, Odile Boesflug-Tanguy, MDPhD, Claire Berger, MD, Yves Bertrand, MD, Liana Carausu, MD, Claire Fieschi, MD PhD, Claire Galambrun, MD, Aline Schmidt, MD, Hubert Journel, MD, Francoise Mazingue, MD, Brigitte Nelken, MD, Thuan Chong Quah, MD, Eric Oksenhendler, MD, Marie Ouachee, MD, Marlène Pasquet, MD, Felipe Suarez, MDPhD, Gérard Pierron, PhD, William Vainchenker, MD PhD, Isabelle Plo, PhD, Jean Donadieu, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): LBA-3.
https://doi.org/10.1182/blood.V130.Suppl_1.LBA-3.LBA-3
Published: 2017
Journal Articles

Prophylactic CNS Therapy (with or without Radiation Therapy) in Medium-High Risk Acute Lymphoblastic Leukemia (ALL) Children: Long-Term Outcome Evaluation of the Randomized BFM-Oriented Trial 58832 (period 1983-1989) of the EORTC Children Leukemia Group

Caroline Piette, Stefan Suciu, Yves Bertrand, Anne Uyttebroeck, Els Vandecruys, Geneviève Plat, Patrick Lutz, Claire Pluchart, Nicolas Sirvent, Maryline Poirée, Pauline Simon, Alina Ferster, Claire Hoyoux, Francoise Mazingue, Robert Paulus, Dominique Plantaz, Caroline Thomas, Caroline Gilotay, Jutte Van Der Werff Ten Bosch, Pierre Simon Rohrlich, Yves Benoit
Journal: Blood
Blood (2016) 128 (22): 2775.
https://doi.org/10.1182/blood.V128.22.2775.2775
Published: 2016
Journal Articles

Impact of Age and Treatment Group in Childhood High Hyperdiploid Low Risk B-Cell Acute Lymphoblastic Leukemia (ALL): Results of the CLG-EORTC 58951 Study

Laura Clement, Stefan Suciu, PhD, Isabelle Luquet, MD, Alina Ferster, MD PhD, Karima Yakouben, MD, Anne Uytterbroeck, Catherine Paillard, MD PhD, Nicolas Sirvent, Vitor Costa, Barbara De Moerloose, MD, Francoise Mazingue, Emmanuel Plouvier, MD, Martine Munzer, Maryline Poirée, Odile Minckes, MD, Frédéric Millot, MD, Dominique Plantaz, Caroline Piette, Frank Speleman, Prof, Hélène Cavé, Jutte VanderWerff-tenBossch, Pierre Simon Rohrlich, MDPhD, Yves Bertrand, Yves Benoit, Geneviève Plat
Journal: Blood
Blood (2016) 128 (22): 1743.
https://doi.org/10.1182/blood.V128.22.1743.1743
Published: 2016
Journal Articles

Pharmacokinetic and Pharmacodynamic Characterization of Graspa Versus Native L-Asparaginase in Combination with Cooprall Chemotherapy in a Phase 3 Randomized Trial for the Treatment of Patients with Relapsed Acute Lymphoblastic Leukemia (NCT01518517)

Xavier Thomas, MD PhD, Yves Bertrand, MDPhD, Andre Baruchel, MD PhD, Nicolas Blin, MD, Emmanuelle Tavernier, MD, Stephane Ducassou, MD, Norbert Vey, Virginie Gandemer, MD PhD, Victoria Cacheux, MD, Francoise Mazingue, MD, Emmanuel Raffoux, Genevieve Plat, MD, Jose Fernandes, MD, Maryline Poiree, MD, Luc Fornecker, MD, Jean-Louis Stephan, MD, Mathilde Hunault, MD PhD, Anne Auvrignon, MD, Thibault Leguay, MD, Stephane Lepretre, MD, Alina Ferster, MD PhD, Isabelle Pellier, MD, Emmanuel Plouvier, MD, Claudine Schmitt, Cecile Bonin, Pharm D, Yann Godfrin, PhD, Iman El Hariry, MDPhD
Journal: Blood
Blood (2015) 126 (23): 2492.
https://doi.org/10.1182/blood.V126.23.2492.2492
Published: 2015
Journal Articles

Updated Clinical Activity of Graspa Versus Native l-Asparaginase in Combination with Cooprall Regimen in Phase 3 Randomized Trial in Patients with Relapsed Acute Lymphoblastic Leukemia (NCT01518517)

Andre Baruchel, MD, Yves Bertrand, MD PhD, Xavier Thomas, MD PhD, Nicolas Blin, MD, Emmanuelle Tavernier, MD, Stephane Ducassou, MD, Norbert Vey, Virginie Gandemer, MD PhD, Victoria Cacheux, MD, Francoise Mazingue, MD, Emmanuel Raffoux, MDPhD, Genevieve PLAT, Jose Fernandes, MD, Poiree Maryline, MD, Luc Fornecker, MD, Jean-Louis Stephan, MD, Mathilde Hunault, MD PhD, Anne Auvrignon, MD, Thibault Leguay, MD, Dominique Plantaz, MDPhD, Stephane Lepretre, MD, Alina Ferster, Isabelle Pellier, MD, Emmanuel Plouvier, MD, Claudine Schmitt, MD, Cecile Bonin, Pharm D, Iman El Hariry, MDPhD
Journal: Blood
Blood (2015) 126 (23): 3723.
https://doi.org/10.1182/blood.V126.23.3723.3723
Published: 2015
Journal Articles

Evaluation of the Impact of the Presence of Neutralizing L-Asparaginase Antibodies on the Efficacy and Safety of Graspa in Phase 3 Randomized Trial Versus Native L-Asparaginase in Patients with Relapsed Acute Lymphoblastic Leukemia (NCT01518517)

Yves Bertrand, MDPhD, Andre Baruchel, MD, Xavier Thomas, MD PhD, Nicolas Blin, MD, Emmanuelle Tavernier, MD, Stephane Ducassou, MD, Norbert Vey, Virginie Gandemer, MD PhD, Victoria Cacheux, MD, Francoise Mazingue, MD, Emmanuel Raffoux, Genevieve Plat, MD, Jose Fernandes, MD, Maryline Poiree, MD, Luc Fornecker, MD, Jean-Louis Stephan, MD, Mathilde Hunault, MD PhD, Anne Auvrignon, MD, Thibault Leguay, MD, Dominique Plantaz, MDPhD, Stephane Lepretre, MD, Alina Ferster, MD PhD, Isabelle Pellier, MD, Emmanuel Plouvier, MD, Claudine Schmitt, Cecile Bonin, Pharm D, Yann Godfrin, PhD, Iman El Hariry, MDPhD
Journal: Blood
Blood (2015) 126 (23): 3734.
https://doi.org/10.1182/blood.V126.23.3734.3734
Published: 2015
Journal Articles

t(12;21)/ ETV6 - RUNX1 Confers a Specific Pattern of In Vivo Sensitivity to Treatments in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL): Results of the Randomized Trials 58881 and 58951 of the EORTC Children Leukemia Group

Caroline Piette, Stefan Suciu, Emmanuelle Clappier, Yves Bertrand, MDPhD, Genevieve Plat, MD, Christophe Chantrain, Vitor Costa, Nicole Dastugue, Alina Ferster, Caroline Gilotay, Sandrine Girard, Nathalie Grardel, Patrick Lutz, Francoise Mazingue, MD, Odile Minckes, Martine Munzer, Emmanuel Plouvier, MD, Nicolas Sirvent, Anne Uyttebroeck, Nadine van Roy, MD, Karima Yakouben, MD, Yves Benoit, Hélène Cavé
Journal: Blood
Blood (2015) 126 (23): 793.
https://doi.org/10.1182/blood.V126.23.793.793
Published: 2015
Journal Articles

Prognostic Relevance of CD200 /Btla Deletions in Pediatric Precursor-B Cell Acute Lymphoblastic Leukemia Treated According to the EORTC-CLG 58951 Protocol

Farzaneh Ghazavi, Tim Lammens, Emmanuelle Clappier, Stefan Suciu, Aurélie Caye, Samira Zegrari, Marleen Bakkus, Nathalie Grardel, Yves Benoit, Yves Bertrand, Odile Minckes, Vitor Costa, Alina Ferster, Françoise Mazingue, Geneviève Plat, Emmanuel Plouvier, Marilyne Poirée, Anne Uyttebroeck, Jutte Van der Werff Ten Bosch, Hetty Helsmoortel, Magali Meul, Nadine Van Roy, Jan Philippé, Frank Speleman, Hélène Cavé, Pieter Van Vlierberghe, Barbara De Moerloose
Journal: Blood
Blood (2014) 124 (21): 2394.
https://doi.org/10.1182/blood.V124.21.2394.2394
Published: 2014
Journal Articles

Impact of early molecular response in children with chronic myeloid leukemia treated in the French Glivec phase 4 study

Brief Report
Frédéric Millot, Joelle Guilhot, André Baruchel, Arnaud Petit, Yves Bertrand, Françoise Mazingue, Patrick Lutz, Cecile Vérité, Christian Berthou, Claire Galambrun, Nicolas Sirvent, Karima Yakouben, Claudine Schmitt, Virginie Gandemer, Yves Reguerre, Gérard Couillault, Françoise Mechinaud, Jean-Michel Cayuela
Journal: Blood
Blood (2014) 124 (15): 2408–2410.
https://doi.org/10.1182/blood-2014-05-578567
Published: 2014
Includes: Supplemental data
Journal Articles

Imatinib Has a Negative Impact On Growth In Children With Previously Untreated Chronic Myeloid Leukaemia (CML) In Early Chronic Phase (CP): Results Of The French National Study

Frédéric Millot, Joelle Guilhot, Ph.D., Andre Baruchel, MD, PhD, Arnaud Petit, MD, Thierry Leblanc, MD, Yves Bertrand, Françoise Mazingue, Patrick Lutz, Cécile Vérité, Christian Berthou, Claire Galambrun, Nicolas Sirvent, Karima Yacouben, Pascal Chastagner, Virginie Gandemer, MD, PhD, Yves Reguerre, Gérard Couillaud, Jean-Michel Cayuela
Journal: Blood
Blood (2013) 122 (21): 4001.
https://doi.org/10.1182/blood.V122.21.4001.4001
Published: 2013
Journal Articles

Molecular Responses At 3 Months Are Associated With a Better Subsequent Molecular response and Outcome In Children and Adolescents With CML In Chronic Phase: Results Of a Retrospective Analysis From The French Glivec Phase 4 Study

Frédéric Millot, Joelle Guilhot, PhD, André Baruchel, MD, Arnaud Petit, MD, Thierry Leblanc, MD, Yves Bertrand, Françoise Mazingue, Patrick Lutz, Cécile Vérité, MD, Christian Berthou, MD, Claire Galambrun, MD, Nicolas Sirvent, Karima Yacouben, Pascal Chastagner, Virginie Gandemer, MD, PhD, Yves Reguerre, MD, Gérard Couillaud, MD, Jean-Michel Cayuela
Journal: Blood
Blood (2013) 122 (21): 2730.
https://doi.org/10.1182/blood.V122.21.2730.2730
Published: 2013
Journal Articles

The Prognosis of Children Acute Lymphoblastic Leukemia (ALL) with Minimal Residual Disease (MRD) ≥10-2 After Induction (TP1) Depends on the Prephase Response and on the Level of the MRD After Consolidation (TP2): Results of the 58951EORTC Trial

Yves Bertrand, Stefan Suciu, Nathalie Grardel, Marleen Bakkus, PhD, Francoise Mazingue, MD, Karima Yacouben, Anne Uyttebroeck, Patrick Lutz, Dominique Plantaz, Sandrine Girard, Nicole Dastugue, Yves Benoit, MD, Hélène Cavé
Journal: Blood
Blood (2011) 118 (21): 2571.
https://doi.org/10.1182/blood.V118.21.2571.2571
Published: 2011
Journal Articles

In Childhood B-Lineage Acute Lymphoblastic Leukemia (B-ALL) with Hyperdiploidy >50 Chromosomes, Patients with 58 to 66 Chromosomes Have 99% EFS At 6-Year Follow-up: Results of the EORTC CLG 58951 Trial

Nicole Dastugue, Stefan Suciu, Geneviève Plat, Frank Speleman, PhD, Hélène Cavé, Sandrine Girard, Emmanuelle Delabesse, Marie Pierre Pagès, Karima Yakouben, Brigitte Nelken, Francoise Mazingue, MD, Anne Hagemeijer, Anne Uyttebroeck, Carine Gervais, MD, Patrick Lutz, Manuel Teixera, Lucilia Norton, Pierre Heimann, Alina Ferster, Ghislaine Plessis, Patrick Boutard, Marie Agnès Collonge, Pierre Rohrlich, MD, PhD, Isabelle Luquet, MD, PhD, Martine Munzer, Nicolas Sirvent, Dominique Plantaz, Christian Herens, Claire Hoyoux, Matthias Karrasch, Yves Bertrand, Yves Benoit, MD
Journal: Blood
Blood (2011) 118 (21): 565.
https://doi.org/10.1182/blood.V118.21.565.565
Published: 2011
Journal Articles

Improved outcome with pulses of vincristine and corticosteroids in continuation therapy of children with average risk acute lymphoblastic leukemia (ALL) and lymphoblastic non-Hodgkin lymphoma (NHL): report of the EORTC randomized phase 3 trial 58951

Clinical Trials & Observations
Barbara De Moerloose, Stefan Suciu, Yves Bertrand, Françoise Mazingue, Alain Robert, Anne Uyttebroeck, Karima Yakouben, Alice Ferster, Geneviève Margueritte, Patrick Lutz, Martine Munzer, Nicolas Sirvent, Lucilia Norton, Patrick Boutard, Dominique Plantaz, Frederic Millot, Pierre Philippet, Liliana Baila, Yves Benoit, Jacques Otten, for the Children's Leukemia Group (CLG) of the European Organisation for Research and Treatment of Cancer (EORTC)
Journal: Blood
Blood (2010) 116 (1): 36–44.
https://doi.org/10.1182/blood-2009-10-247965
Published: 2010
Includes: Supplemental data
Journal Articles

Improvement of Supportive Care in Patients Undergoing Myeloablative Allogeneic Stem Cell Transplantation Not Only Reduces Transplant-Related Mortality but Also Increases Long-Term Survival

Benedicte Bruno, MD, David Seguy, MD, Vincent Maunoury, MD, PhD, Valerie Coiteux, MD, Leonardo Magro, MD, Francis Bauters, MD, Francoise Mazingue, MD, Jean-Pierre Jouet, MD, Ibrahim Yakoub-Agha, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 4318.
https://doi.org/10.1182/blood.V112.11.4318.4318
Published: 2008
Journal Articles

Improved Outcome with Pulses of Vincristine and Steroids in Continuation Therapy of Children with Average Risk Acute Lymphoblastic Leukemia (ALL) and Non Hodgkin Lymphoma (NHL): Final Report of the EORTC Randomized Phase III Trial 58951

Barbara De Moerloose, Stefan Suciu, Yves Bertrand, Francoise Mazingue, Alain Robert, Anne Uyttebroeck, Karima Yacouben, Alina Ferster, Geneviève Margueritte, Patrick Lutz, Martine Munzer, Nicolas Sirvent, Lucilia Norton, Patrick Boutard, Dominique Plantaz, Frédéric Millot, Pierre Philippet, Liliana Baila, Yves Benoit, Jacques Otten
Journal: Blood
Blood (2008) 112 (11): 11.
https://doi.org/10.1182/blood.V112.11.11.11
Published: 2008
Journal Articles

Prognostic Significance of Blasts with/without Pleiocytosis in the Cerebro-Spinal Fluid (CSF) of Children with Acute Lymphoblastic Leukemia (ALL) Treated without Cranial Irradiation: Results of European Organization for Research and Treatment of Cancer (EORTC) Children Leukemia Group Study 58881.

Nicolas Sirvent, Stefan Suciu, Xavier Rialland, Alain Robert, Francoise Mazingue, Frederic Millot, Barbara De Moerloose, Alice Ferster, Pierre Rohrlich, Lucilia Norton, Brigitte Lescoeur, Marie-Francoiseçoise Dresse, Patrick Lutz, Liliana Baila, Catherine Behar, Yves Bertrand, Jacques Otten
Journal: Blood
Blood (2006) 108 (11): 149.
https://doi.org/10.1182/blood.V108.11.149.149
Published: 2006